ATE488514T1 - Piperidinverbindungen und anwendungen davon - Google Patents

Piperidinverbindungen und anwendungen davon

Info

Publication number
ATE488514T1
ATE488514T1 AT08762541T AT08762541T ATE488514T1 AT E488514 T1 ATE488514 T1 AT E488514T1 AT 08762541 T AT08762541 T AT 08762541T AT 08762541 T AT08762541 T AT 08762541T AT E488514 T1 ATE488514 T1 AT E488514T1
Authority
AT
Austria
Prior art keywords
piperidine compounds
piperidine
compounds
Prior art date
Application number
AT08762541T
Other languages
English (en)
Inventor
Gregory Basarab
Pamela Hill
Fei Zhou
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE488514T1 publication Critical patent/ATE488514T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT08762541T 2007-06-12 2008-06-11 Piperidinverbindungen und anwendungen davon ATE488514T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94344007P 2007-06-12 2007-06-12
PCT/GB2008/050431 WO2008152418A1 (en) 2007-06-12 2008-06-11 Piperidine compounds and uses thereof

Publications (1)

Publication Number Publication Date
ATE488514T1 true ATE488514T1 (de) 2010-12-15

Family

ID=39673349

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08762541T ATE488514T1 (de) 2007-06-12 2008-06-11 Piperidinverbindungen und anwendungen davon

Country Status (29)

Country Link
US (1) US20080312255A1 (de)
EP (1) EP2158199B1 (de)
JP (1) JP2010529184A (de)
KR (1) KR20100038095A (de)
CN (1) CN102648199A (de)
AR (1) AR066977A1 (de)
AT (1) ATE488514T1 (de)
AU (1) AU2008263580A1 (de)
BR (1) BRPI0812473A2 (de)
CA (1) CA2689076A1 (de)
CL (1) CL2008001740A1 (de)
CO (1) CO6311102A2 (de)
CY (1) CY1111442T1 (de)
DE (1) DE602008003575D1 (de)
DK (1) DK2158199T3 (de)
ES (1) ES2354647T3 (de)
HR (1) HRP20110048T1 (de)
IL (1) IL202367A0 (de)
MX (1) MX2009013501A (de)
NZ (1) NZ582516A (de)
PE (1) PE20090555A1 (de)
PL (1) PL2158199T3 (de)
PT (1) PT2158199E (de)
RU (1) RU2010100352A (de)
SA (1) SA08290357B1 (de)
SI (1) SI2158199T1 (de)
TW (1) TW200906412A (de)
UY (1) UY31141A1 (de)
WO (1) WO2008152418A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1853586B1 (de) 2005-02-18 2013-07-24 AstraZeneca AB Antibakterielle piperidinderivate
US8071605B2 (en) 2008-12-12 2011-12-06 Astrazeneca Ab Piperidine compounds for use in the treatment of bacterial infections
TW201026694A (en) * 2008-12-12 2010-07-16 Astrazeneca Ab Compound 468
AR077971A1 (es) 2009-08-26 2011-10-05 Astrazeneca Ab Derivados heterociclicos de urea y metodos de uso de los mismos
WO2014164195A1 (en) * 2013-03-13 2014-10-09 Avon Products, Inc Tyrosinase inhibitors
US20150174034A1 (en) 2013-03-13 2015-06-25 Avon Products, Inc. Tyrosinase inhibitors
CN108137574B (zh) 2015-09-30 2021-12-28 第一三共株式会社 羟烷基噻二唑衍生物
EP3596071A1 (de) 2017-03-14 2020-01-22 Daiichi Sankyo Company, Limited N-phosphonoxymethyl-prodrugs von hydroxyalkylthiadiazolderivaten
CN110446699A (zh) 2017-03-24 2019-11-12 大正制药株式会社 2（1h）-喹啉酮衍生物
WO2020048949A1 (en) 2018-09-03 2020-03-12 Univerza V Ljubljani New class of dna gyrase and/or topoisomerase iv inhibitors with activity against gram-positive and gram-negative bacteria
CN110172435B (zh) * 2019-06-06 2020-12-29 江南大学 一种催化合成2,5-二甲基吡嗪的重组菌
EP4263503A1 (de) 2020-12-17 2023-10-25 Univerza V Ljubljani Neue n-phenylpyrrolamid-inhibitoren der dna-gyrase und topoisomerase iv mit antibakterieller wirkung
CN115466246B (zh) * 2021-06-11 2024-02-06 中国医学科学院药物研究所 吡咯酰哌啶胺类化合物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3963480A (en) * 1973-04-11 1976-06-15 Sterling Drug Inc. Herbicidal pyrrole-2-carboxamides
US4046775A (en) * 1973-04-11 1977-09-06 Sterling Drug Inc. 4,5-Dihalopyrrole-2-carboxamides
US4791112A (en) * 1987-02-02 1988-12-13 The Boc Group, Inc. N-heterocyclic-N-(4-piperidyl)amides and pharmaceutical compositions and methods employing such compounds
US4912109A (en) * 1987-02-02 1990-03-27 Boc, Inc. N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compositions and methods employing such compounds
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
NZ520628A (en) * 2000-01-18 2004-05-28 Vertex Pharma thiazole, oxazole, imdazole or pyrazole substituted pyrazole derivatives useful as treating bacterial infections
CA2489128C (en) * 2002-06-13 2012-01-03 Vertex Pharmaceuticals Incorporated 2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives and related compounds as gyrase and/or topoisomerase iv inhibitors for the treatment of bacterial infections
TW200526626A (en) * 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
GB0321509D0 (en) * 2003-09-13 2003-10-15 Astrazeneca Ab Chemical compounds
US20050197336A1 (en) * 2004-03-08 2005-09-08 Miikana Therapeutics Corporation Inhibitors of histone deacetylase
US7345043B2 (en) * 2004-04-01 2008-03-18 Miikana Therapeutics Inhibitors of histone deacetylase
EP1853586B1 (de) * 2005-02-18 2013-07-24 AstraZeneca AB Antibakterielle piperidinderivate
TW200819437A (en) * 2006-08-17 2008-05-01 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
IL202367A0 (en) 2010-06-30
CO6311102A2 (es) 2011-08-22
NZ582516A (en) 2012-03-30
US20080312255A1 (en) 2008-12-18
PL2158199T3 (pl) 2011-04-29
ES2354647T3 (es) 2011-03-16
BRPI0812473A2 (pt) 2014-12-02
CL2008001740A1 (es) 2009-07-17
TW200906412A (en) 2009-02-16
WO2008152418A1 (en) 2008-12-18
AU2008263580A1 (en) 2008-12-18
EP2158199B1 (de) 2010-11-17
PT2158199E (pt) 2011-01-19
PE20090555A1 (es) 2009-06-04
UY31141A1 (es) 2009-01-30
EP2158199A1 (de) 2010-03-03
MX2009013501A (es) 2010-01-18
CY1111442T1 (el) 2015-08-05
KR20100038095A (ko) 2010-04-12
HK1140198A1 (en) 2010-10-08
DE602008003575D1 (de) 2010-12-30
JP2010529184A (ja) 2010-08-26
DK2158199T3 (da) 2011-02-07
CA2689076A1 (en) 2008-12-18
SI2158199T1 (sl) 2011-02-28
AR066977A1 (es) 2009-09-23
SA08290357B1 (ar) 2011-06-22
HRP20110048T1 (hr) 2011-03-31
RU2010100352A (ru) 2011-07-20
CN102648199A (zh) 2012-08-22

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