ATE488767T1 - Verfahren zum nachweis der aktivierung von t- zellen durch mhc-bindende peptide - Google Patents

Verfahren zum nachweis der aktivierung von t- zellen durch mhc-bindende peptide

Info

Publication number
ATE488767T1
ATE488767T1 AT04779108T AT04779108T ATE488767T1 AT E488767 T1 ATE488767 T1 AT E488767T1 AT 04779108 T AT04779108 T AT 04779108T AT 04779108 T AT04779108 T AT 04779108T AT E488767 T1 ATE488767 T1 AT E488767T1
Authority
AT
Austria
Prior art keywords
mhc
detecting
cell activation
methods
binding peptides
Prior art date
Application number
AT04779108T
Other languages
English (en)
Inventor
Jennie Chyan Chuu Chang
Suha Kasey
Veronique Trigueros Crebassa
Felix A Montero-Julian
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Application granted granted Critical
Publication of ATE488767T1 publication Critical patent/ATE488767T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT04779108T 2003-07-22 2004-07-22 Verfahren zum nachweis der aktivierung von t- zellen durch mhc-bindende peptide ATE488767T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48935903P 2003-07-22 2003-07-22
PCT/US2004/023898 WO2005010026A2 (en) 2003-07-22 2004-07-22 Methods for detecting activation of t-cells by mhc binding peptides

Publications (1)

Publication Number Publication Date
ATE488767T1 true ATE488767T1 (de) 2010-12-15

Family

ID=34102856

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04779108T ATE488767T1 (de) 2003-07-22 2004-07-22 Verfahren zum nachweis der aktivierung von t- zellen durch mhc-bindende peptide

Country Status (4)

Country Link
EP (1) EP1648919B1 (de)
AT (1) ATE488767T1 (de)
DE (1) DE602004030125D1 (de)
WO (1) WO2005010026A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040072262A1 (en) 2002-10-11 2004-04-15 Montero-Julian Felix A. Methods and systems for detecting MHC class I binding peptides
CN101529251B (zh) 2006-11-01 2014-04-02 贝克曼考尔特公司 用于亲合分析的结合性表面
FR2992427A1 (fr) * 2012-06-20 2013-12-27 Assist Publ Hopitaux De Paris Methode de pronostic d'un lymphome et kit pour sa mise en oeuvre
EP3182125A1 (de) * 2015-12-16 2017-06-21 Ab Tcer T-zellreaktivitätsplattform
CN113552343A (zh) * 2015-12-16 2021-10-26 Neogap治疗学公司 T细胞反应性平台
EP3455630A4 (de) * 2016-05-13 2020-01-08 MBL International Corp. Peptidaustauschsystem und -verfahren
EP3509629A1 (de) 2016-09-06 2019-07-17 H. Hoffnabb-La Roche Ag Mhc-gebundene peptid-arrays und verfahren zur verwendung davon
WO2021083807A1 (en) * 2019-10-29 2021-05-06 Universitaet Heidelberg Artificial antigen presenting molecules and their uses
WO2025125528A1 (en) 2023-12-14 2025-06-19 Miltenyi Biotec B.V. & Co. KG Multiplex mhc peptide binding and t cell detection method / quantifiable multiplex mhc binding assay

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635363A (en) 1995-02-28 1997-06-03 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for the detection, quantitation and purification of antigen-specific T cells
EP1287363A2 (de) * 2000-05-25 2003-03-05 Sunol Molecular Corporation Modulation von wechselwirkungen in t-zellrezeptoren
US7094555B2 (en) * 2001-04-05 2006-08-22 Benaroya Research Institute At Virginia Mason Methods of MHC class II epitope mapping, detection of autoimmune T cells and antigens, and autoimmune treatment
JP2005514617A (ja) * 2001-07-02 2005-05-19 ザ、ボード、オブ、トラスティーズ、オブ、ザ、リーランド、スタンフォード、ジュニア、ユニバーシティ 細胞の表現型決定および操作のためのマイクロアレイ
US20040248205A1 (en) * 2003-04-16 2004-12-09 Stern Lawrence J. Major histocompatibility complex (MHC)-peptide arrays

Also Published As

Publication number Publication date
WO2005010026A2 (en) 2005-02-03
EP1648919B1 (de) 2010-11-17
DE602004030125D1 (de) 2010-12-30
EP1648919A2 (de) 2006-04-26
EP1648919A4 (de) 2007-08-01
WO2005010026A3 (en) 2005-06-02

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