ATE489626T1 - Verfahren zum screenen von mhc- rezeptorantagonisten oder -agonisten - Google Patents
Verfahren zum screenen von mhc- rezeptorantagonisten oder -agonistenInfo
- Publication number
- ATE489626T1 ATE489626T1 AT01947822T AT01947822T ATE489626T1 AT E489626 T1 ATE489626 T1 AT E489626T1 AT 01947822 T AT01947822 T AT 01947822T AT 01947822 T AT01947822 T AT 01947822T AT E489626 T1 ATE489626 T1 AT E489626T1
- Authority
- AT
- Austria
- Prior art keywords
- salt
- slt
- agonists
- screening
- receptor antagonists
- Prior art date
Links
- 238000012216 screening Methods 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000000018 receptor agonist Substances 0.000 title 1
- 229940044601 receptor agonist Drugs 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 7
- 150000001408 amides Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000036528 appetite Effects 0.000 abstract 1
- 235000019789 appetite Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000208254 | 2000-07-05 | ||
| PCT/JP2001/005809 WO2002003070A1 (en) | 2000-07-05 | 2001-07-04 | Method for screening mch receptor antagonist/agonist |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489626T1 true ATE489626T1 (de) | 2010-12-15 |
Family
ID=18704874
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01947822T ATE489626T1 (de) | 2000-07-05 | 2001-07-04 | Verfahren zum screenen von mhc- rezeptorantagonisten oder -agonisten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7273710B2 (de) |
| EP (1) | EP1298439B1 (de) |
| AT (1) | ATE489626T1 (de) |
| AU (1) | AU2001269440A1 (de) |
| DE (1) | DE60143525D1 (de) |
| WO (1) | WO2002003070A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221613B1 (en) | 1998-12-31 | 2001-04-24 | Synaptic Pharmaceutical Corporation | DNA encoding a human melanin concentrating hormone receptor (MCH1) and uses thereof |
| US7078484B2 (en) | 2001-04-19 | 2006-07-18 | Neurogen Corporation | Melanin concentrating hormone receptors |
| US7078187B2 (en) | 2001-04-19 | 2006-07-18 | Neurogen Corporation | Melanin concentrating hormone receptors |
| WO2002089729A2 (en) | 2001-05-04 | 2002-11-14 | Tularik Inc. | Fused heterocyclic compounds |
| US6809104B2 (en) | 2001-05-04 | 2004-10-26 | Tularik Inc. | Fused heterocyclic compounds |
| WO2003007887A2 (en) | 2001-07-20 | 2003-01-30 | Merck & Co., Inc. | Substituted imidazoles as cannabinoid receptor modulators |
| US7141391B2 (en) | 2001-11-13 | 2006-11-28 | Neurogen Corporation | Monkey and canine melanin concentrating hormone receptors |
| WO2004043958A1 (en) | 2002-11-06 | 2004-05-27 | Amgen Inc. | Fused heterocyclic compounds |
| JP4593639B2 (ja) * | 2008-03-04 | 2010-12-08 | 株式会社マルハニチロ食品 | ペプチド含有摂食調節剤 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999028492A1 (en) | 1997-12-03 | 1999-06-10 | Smithkline Beecham Corporation | A method of finding agonist and antagonist to human 11cb splice variant |
| CN1344321A (zh) | 1998-12-28 | 2002-04-10 | 武田药品工业株式会社 | 筛选方法 |
| EP1153932A1 (de) | 1999-02-19 | 2001-11-14 | Takeda Chemical Industries, Ltd. | G-Protein gekoppeltes Rezeptorprotein und DNA |
| WO2001007606A1 (en) | 1999-07-27 | 2001-02-01 | Smithkline Beecham Plc | Axor21, a g-protein coupled receptor |
| JP2003514549A (ja) | 1999-11-16 | 2003-04-22 | メルク エンド カムパニー インコーポレーテッド | Ｇタンパク質共役受容体 |
| EP1255770A4 (de) | 2000-02-03 | 2004-12-08 | Merck & Co Inc | Analoge des melanin konzentrierenden hormons |
| JP2005229804A (ja) | 2000-03-24 | 2005-09-02 | Astellas Pharma Inc | 新規なメラニンコンセントレーティングホルモン受容体 |
-
2001
- 2001-07-04 AT AT01947822T patent/ATE489626T1/de not_active IP Right Cessation
- 2001-07-04 DE DE60143525T patent/DE60143525D1/de not_active Expired - Lifetime
- 2001-07-04 EP EP01947822A patent/EP1298439B1/de not_active Expired - Lifetime
- 2001-07-04 US US10/332,082 patent/US7273710B2/en not_active Expired - Fee Related
- 2001-07-04 AU AU2001269440A patent/AU2001269440A1/en not_active Abandoned
- 2001-07-04 WO PCT/JP2001/005809 patent/WO2002003070A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20040086941A1 (en) | 2004-05-06 |
| DE60143525D1 (de) | 2011-01-05 |
| EP1298439A1 (de) | 2003-04-02 |
| AU2001269440A1 (en) | 2002-01-14 |
| EP1298439B1 (de) | 2010-11-24 |
| US7273710B2 (en) | 2007-09-25 |
| EP1298439A4 (de) | 2005-11-23 |
| WO2002003070A1 (en) | 2002-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |