ATE489630T1 - Verfahren zur bestimmung von konformationsänderungen und selbstzusammenbau von proteinen - Google Patents
Verfahren zur bestimmung von konformationsänderungen und selbstzusammenbau von proteinenInfo
- Publication number
- ATE489630T1 ATE489630T1 AT05711108T AT05711108T ATE489630T1 AT E489630 T1 ATE489630 T1 AT E489630T1 AT 05711108 T AT05711108 T AT 05711108T AT 05711108 T AT05711108 T AT 05711108T AT E489630 T1 ATE489630 T1 AT E489630T1
- Authority
- AT
- Austria
- Prior art keywords
- conformational changes
- proteins
- protein
- self
- assembly
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 6
- 108090000623 proteins and genes Proteins 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 2
- 238000001338 self-assembly Methods 0.000 title abstract 2
- 229920000867 polyelectrolyte Polymers 0.000 abstract 4
- 230000003941 amyloidogenesis Effects 0.000 abstract 2
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0401219A SE0401219D0 (sv) | 2004-05-10 | 2004-05-10 | Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter |
| PCT/SE2005/000248 WO2005109005A1 (en) | 2004-05-10 | 2005-02-22 | Methods for determining conformational changes and self-assembly of proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489630T1 true ATE489630T1 (de) | 2010-12-15 |
Family
ID=32390923
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05711108T ATE489630T1 (de) | 2004-05-10 | 2005-02-22 | Verfahren zur bestimmung von konformationsänderungen und selbstzusammenbau von proteinen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7867718B2 (de) |
| EP (1) | EP1766410B1 (de) |
| JP (1) | JP4777979B2 (de) |
| AT (1) | ATE489630T1 (de) |
| AU (1) | AU2005241371B2 (de) |
| CA (1) | CA2608177C (de) |
| DE (1) | DE602005024962D1 (de) |
| NZ (1) | NZ551781A (de) |
| SE (1) | SE0401219D0 (de) |
| WO (1) | WO2005109005A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9371559B2 (en) | 2002-06-20 | 2016-06-21 | The Regents Of The University Of California | Compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
| US7144950B2 (en) | 2003-09-17 | 2006-12-05 | The Regents Of The University Of California | Conformationally flexible cationic conjugated polymers |
| US10001475B2 (en) | 2002-06-20 | 2018-06-19 | The Regents Of The University Of California | Light harvesting multichromophore compositions and methods of using the same |
| CA2497152C (en) * | 2002-08-26 | 2016-06-07 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
| CN1771335A (zh) * | 2003-02-13 | 2006-05-10 | 加州大学评议会 | 使用集光多生色团检测和分析多核苷酸-结合蛋白相互作用的方法和组合物 |
| SE0400783D0 (sv) * | 2004-03-24 | 2004-03-24 | Peter Aasberg | Mönstringsmetod för biosensorapplikationer |
| WO2006074471A2 (en) | 2005-01-10 | 2006-07-13 | The Regents Of The University Of California | Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays |
| WO2006074482A2 (en) * | 2005-01-10 | 2006-07-13 | The Regents Of The University Of California | Methods and kits for strand-specific polynucleotide detection with cationic multichromophores |
| US7666594B2 (en) * | 2005-01-31 | 2010-02-23 | The Regents Of The University Of California | Methods for assaying a sample for an aggregant |
| EP1996951A1 (de) * | 2006-02-09 | 2008-12-03 | BioChromix AB | Verfahren zum nachweis krankheitserregender prionproteine in verbindung mit prionenkrankheiten unter verwendung konjugierter polyelektrolyte |
| JP5420414B2 (ja) | 2006-10-06 | 2014-02-19 | シリゲン グループ リミテッド | 指向性バイオマーカシグナル増幅用の蛍光方法および材料 |
| CN101578520B (zh) | 2006-10-18 | 2015-09-16 | 哈佛学院院长等 | 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法 |
| CA2721770A1 (en) | 2007-04-18 | 2008-10-30 | Biochromix Ab | Medical use of conjugated polyelectrolytes |
| US20100310462A1 (en) * | 2007-04-18 | 2010-12-09 | Biochromix Ab | Binding of pathological forms of proteins using conjugated polyelectrolytes |
| US20100310461A1 (en) * | 2007-04-18 | 2010-12-09 | Biochromix Pharma Ab | Binding of pathological forms of proteins using conjugated polyelectrolytes |
| CN106443002A (zh) * | 2007-10-22 | 2017-02-22 | 贝克顿·迪金森公司 | 评价在含有机基聚硅氧烷的悬浮液中蛋白质聚集的方法 |
| KR20100128340A (ko) | 2008-03-27 | 2010-12-07 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 종이 기반 마이크로유체 시스템 |
| KR101510785B1 (ko) | 2008-03-27 | 2015-04-10 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 저렴한 멀티 검사 진단 플랫폼으로서의 무명실 |
| US8628729B2 (en) | 2008-03-27 | 2014-01-14 | President And Fellows Of Harvard College | Three-dimensional microfluidic devices |
| WO2010044744A1 (en) * | 2008-10-17 | 2010-04-22 | Biochromix Ab | Novel thiophene compounds for in vivo imaging |
| ES2612507T3 (es) | 2009-03-06 | 2017-05-17 | President And Fellows Of Harvard College | Dispositivos microfluídicos y electroquímicos |
| SG177355A1 (en) | 2009-06-26 | 2012-02-28 | Sirigen Inc | Signal amplified biological detection with conjugated polymers |
| ES2977359T3 (es) | 2010-01-19 | 2024-08-22 | Sirigen Ii Ltd | Nuevos reactivos para la amplificación dirigida de la señal de un biomarcador |
| CN102821861B (zh) | 2010-02-03 | 2015-03-25 | 哈佛大学校长及研究员协会 | 用于多重测定的装置和方法 |
| DK2536712T3 (da) * | 2010-02-16 | 2015-06-15 | Celluminova Ab | Oligothiophenderivat som molekulære sonder |
| WO2012017739A1 (ja) * | 2010-07-31 | 2012-02-09 | エレコン科学株式会社 | アミロイドアッセイ装置およびアミロイドアッセイ方法 |
| US9001319B2 (en) | 2012-05-04 | 2015-04-07 | Ecolab Usa Inc. | Self-cleaning optical sensor |
| US9140648B2 (en) | 2013-03-12 | 2015-09-22 | Ecolab Usa Inc. | Fluorometer with multiple detection channels |
| CN107063940B (zh) | 2016-02-10 | 2019-10-18 | 贝克顿迪金森法国公司 | 用于评价基于蛋白质的制剂的稳定性的方法 |
| WO2019217603A1 (en) * | 2018-05-08 | 2019-11-14 | Shanghaitech University | An amyloid-based fundamental building material with integrated genetically programmable functionality |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545531A (en) * | 1995-06-07 | 1996-08-13 | Affymax Technologies N.V. | Methods for making a device for concurrently processing multiple biological chip assays |
| US5985242A (en) * | 1995-10-27 | 1999-11-16 | Praecis Pharmaceuticals, Inc. | Modulators of β-amyloid peptide aggregation comprising D-amino acids |
| EP1112377A4 (de) * | 1998-06-22 | 2004-11-10 | Univ California | Nukleinsäure-gekoppelte kolorimetrische analytdetektoren |
| JP2000344685A (ja) * | 1999-03-26 | 2000-12-12 | Bf Kenkyusho:Kk | アズールa類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| US6399314B1 (en) * | 1999-12-29 | 2002-06-04 | American Cyanamid Company | Methods of detection of amyloidogenic proteins |
| CA2409512A1 (en) * | 2000-05-08 | 2001-11-15 | Qtl Biosystems Llc | Improvements to the fluorescent polymer-qtl approach to biosensing |
| JP2002275099A (ja) * | 2001-03-16 | 2002-09-25 | Bf Kenkyusho:Kk | ベンゾシアゾリン環またはベンゾオキサゾリン環を含む化合物による、アミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物 |
| WO2002081735A2 (en) | 2001-04-05 | 2002-10-17 | Infectio Diagnostic (I.D.I.), Inc. | Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives |
| SE0201468D0 (sv) * | 2002-05-13 | 2002-05-13 | Peter Aasberg | Metod att använda luminescenta polymerer för detektion av biospecifik växelverkan |
-
2004
- 2004-05-10 SE SE0401219A patent/SE0401219D0/xx unknown
-
2005
- 2005-02-22 WO PCT/SE2005/000248 patent/WO2005109005A1/en not_active Ceased
- 2005-02-22 NZ NZ551781A patent/NZ551781A/en not_active IP Right Cessation
- 2005-02-22 EP EP05711108A patent/EP1766410B1/de not_active Expired - Lifetime
- 2005-02-22 CA CA2608177A patent/CA2608177C/en not_active Expired - Fee Related
- 2005-02-22 AU AU2005241371A patent/AU2005241371B2/en not_active Ceased
- 2005-02-22 AT AT05711108T patent/ATE489630T1/de not_active IP Right Cessation
- 2005-02-22 JP JP2007513098A patent/JP4777979B2/ja not_active Expired - Fee Related
- 2005-02-22 DE DE602005024962T patent/DE602005024962D1/de not_active Expired - Lifetime
- 2005-02-22 US US11/579,741 patent/US7867718B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1766410A1 (de) | 2007-03-28 |
| AU2005241371B2 (en) | 2010-09-09 |
| DE602005024962D1 (de) | 2011-01-05 |
| NZ551781A (en) | 2010-07-30 |
| US20080038751A1 (en) | 2008-02-14 |
| WO2005109005A1 (en) | 2005-11-17 |
| CA2608177A1 (en) | 2005-11-17 |
| JP4777979B2 (ja) | 2011-09-21 |
| SE0401219D0 (sv) | 2004-05-10 |
| AU2005241371A1 (en) | 2005-11-17 |
| EP1766410B1 (de) | 2010-11-24 |
| JP2007536555A (ja) | 2007-12-13 |
| US7867718B2 (en) | 2011-01-11 |
| CA2608177C (en) | 2013-06-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |