SE0401219D0 - Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter - Google Patents

Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter

Info

Publication number
SE0401219D0
SE0401219D0 SE0401219A SE0401219A SE0401219D0 SE 0401219 D0 SE0401219 D0 SE 0401219D0 SE 0401219 A SE0401219 A SE 0401219A SE 0401219 A SE0401219 A SE 0401219A SE 0401219 D0 SE0401219 D0 SE 0401219D0
Authority
SE
Sweden
Prior art keywords
conformational changes
aggregation
proteins
methods
protein
Prior art date
Application number
SE0401219A
Other languages
English (en)
Swedish (sv)
Inventor
Peter Nilsson
Anna Herland
Per Hammarstroem
Peter Aasberg
Olle Inganaes
Original Assignee
Biochromix Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochromix Ab filed Critical Biochromix Ab
Priority to SE0401219A priority Critical patent/SE0401219D0/xx
Publication of SE0401219D0 publication Critical patent/SE0401219D0/xx
Priority to EP05711108A priority patent/EP1766410B1/de
Priority to US11/579,741 priority patent/US7867718B2/en
Priority to CA2608177A priority patent/CA2608177C/en
Priority to DE602005024962T priority patent/DE602005024962D1/de
Priority to JP2007513098A priority patent/JP4777979B2/ja
Priority to AU2005241371A priority patent/AU2005241371B2/en
Priority to NZ551781A priority patent/NZ551781A/en
Priority to PCT/SE2005/000248 priority patent/WO2005109005A1/en
Priority to AT05711108T priority patent/ATE489630T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
SE0401219A 2004-05-10 2004-05-10 Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter SE0401219D0 (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE0401219A SE0401219D0 (sv) 2004-05-10 2004-05-10 Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter
EP05711108A EP1766410B1 (de) 2004-05-10 2005-02-22 Verfahren zur bestimmung von konformationsänderungen und selbstzusammenbau von proteinen
US11/579,741 US7867718B2 (en) 2004-05-10 2005-02-22 Methods for determining conformational changes and self-assembly of proteins
CA2608177A CA2608177C (en) 2004-05-10 2005-02-22 Methods for determining conformational changes and self-assembly of proteins
DE602005024962T DE602005024962D1 (de) 2004-05-10 2005-02-22 Verfahren zur bestimmung von konformationsänderungen und selbstzusammenbau von proteinen
JP2007513098A JP4777979B2 (ja) 2004-05-10 2005-02-22 タンパク質のコンホメーション変化及び自己集合を決定するための方法
AU2005241371A AU2005241371B2 (en) 2004-05-10 2005-02-22 Methods for determining conformational changes and self-assembly of proteins
NZ551781A NZ551781A (en) 2004-05-10 2005-02-22 Methods for determining conformational changes and self-assembly of proteins
PCT/SE2005/000248 WO2005109005A1 (en) 2004-05-10 2005-02-22 Methods for determining conformational changes and self-assembly of proteins
AT05711108T ATE489630T1 (de) 2004-05-10 2005-02-22 Verfahren zur bestimmung von konformationsänderungen und selbstzusammenbau von proteinen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0401219A SE0401219D0 (sv) 2004-05-10 2004-05-10 Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter

Publications (1)

Publication Number Publication Date
SE0401219D0 true SE0401219D0 (sv) 2004-05-10

Family

ID=32390923

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0401219A SE0401219D0 (sv) 2004-05-10 2004-05-10 Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter

Country Status (10)

Country Link
US (1) US7867718B2 (de)
EP (1) EP1766410B1 (de)
JP (1) JP4777979B2 (de)
AT (1) ATE489630T1 (de)
AU (1) AU2005241371B2 (de)
CA (1) CA2608177C (de)
DE (1) DE602005024962D1 (de)
NZ (1) NZ551781A (de)
SE (1) SE0401219D0 (de)
WO (1) WO2005109005A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7144950B2 (en) * 2003-09-17 2006-12-05 The Regents Of The University Of California Conformationally flexible cationic conjugated polymers
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
US9371559B2 (en) 2002-06-20 2016-06-21 The Regents Of The University Of California Compositions for detection and analysis of polynucleotides using light harvesting multichromophores
KR20050055717A (ko) 2002-08-26 2005-06-13 더 리전츠 오브 더 유니버시티 오브 캘리포니아 집광 다발색단을 사용하여 폴리뉴클레오티드를 검출 및 분석하기 위한 방법 및 조성물
ES2440920T3 (es) * 2003-02-13 2014-01-31 The Regents Of The University Of California Métodos y composiciones para la detección y análisis de interacciones de proteínas que se unen a polinucleótidos utilizando multicromóforos captadores de luz
SE0400783D0 (sv) * 2004-03-24 2004-03-24 Peter Aasberg Mönstringsmetod för biosensorapplikationer
WO2006074482A2 (en) * 2005-01-10 2006-07-13 The Regents Of The University Of California Methods and kits for strand-specific polynucleotide detection with cationic multichromophores
US7897684B2 (en) 2005-01-10 2011-03-01 The Regents Of The University Of California Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
US7666594B2 (en) * 2005-01-31 2010-02-23 The Regents Of The University Of California Methods for assaying a sample for an aggregant
WO2007091973A1 (en) * 2006-02-09 2007-08-16 Biochromix Ab Methods for detection of pathogenic prion proteins associated with prion diseases, using conjugated polyelectrolytes
US8158444B2 (en) 2006-10-06 2012-04-17 Sirigen, Inc. Fluorescent methods and materials for directed biomarker signal amplification
CN101578520B (zh) 2006-10-18 2015-09-16 哈佛学院院长等 基于形成图案的多孔介质的横向流动和穿过生物测定装置、及其制备方法和使用方法
CA2721770A1 (en) * 2007-04-18 2008-10-30 Biochromix Ab Medical use of conjugated polyelectrolytes
US20100310461A1 (en) * 2007-04-18 2010-12-09 Biochromix Pharma Ab Binding of pathological forms of proteins using conjugated polyelectrolytes
US20100310462A1 (en) * 2007-04-18 2010-12-09 Biochromix Ab Binding of pathological forms of proteins using conjugated polyelectrolytes
EP2237038B1 (de) 2007-10-22 2015-04-29 Becton Dickinson and Company Medizinische Artikel mit Beschichtung aus Ogranopolysiloxan mit einer Proteinlösung und nichtionisches Tensid
US8628729B2 (en) 2008-03-27 2014-01-14 President And Fellows Of Harvard College Three-dimensional microfluidic devices
WO2009121043A2 (en) 2008-03-27 2009-10-01 President And Fellows Of Harvard College Cotton thread as a low-cost multi-assay diagnostic platform
WO2009121041A2 (en) 2008-03-27 2009-10-01 President And Fellows Of Harvard College Paper-based microfluidic systems
EP2350042B1 (de) 2008-10-17 2015-07-29 Cpl Bcx Pharma Ab Neue thiophenverbindungen für therapeutische zwecke
PL2403645T3 (pl) 2009-03-06 2017-05-31 President And Fellows Of Harvard College Mikroprzepływowe, elektrochemiczne urządzenia
SG177355A1 (en) 2009-06-26 2012-02-28 Sirigen Inc Signal amplified biological detection with conjugated polymers
CA2786713C (en) 2010-01-19 2018-03-06 Sirigen Group Limited Novel reagents for directed biomarker signal amplification
AU2011212916B2 (en) 2010-02-03 2015-07-02 President And Fellows Of Harvard College Devices and methods for multiplexed assays
ES2539475T3 (es) * 2010-02-16 2015-07-01 Celluminova Ab Derivados de oligotiofeno como sondas moleculares
JP5841945B2 (ja) * 2010-07-31 2016-01-13 祐児 後藤 アミロイドアッセイ装置およびアミロイドアッセイ方法
US9001319B2 (en) 2012-05-04 2015-04-07 Ecolab Usa Inc. Self-cleaning optical sensor
US9140648B2 (en) 2013-03-12 2015-09-22 Ecolab Usa Inc. Fluorometer with multiple detection channels
CN107063940B (zh) 2016-02-10 2019-10-18 贝克顿迪金森法国公司 用于评价基于蛋白质的制剂的稳定性的方法
WO2019217603A1 (en) * 2018-05-08 2019-11-14 Shanghaitech University An amyloid-based fundamental building material with integrated genetically programmable functionality

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545531A (en) * 1995-06-07 1996-08-13 Affymax Technologies N.V. Methods for making a device for concurrently processing multiple biological chip assays
US5985242A (en) * 1995-10-27 1999-11-16 Praecis Pharmaceuticals, Inc. Modulators of β-amyloid peptide aggregation comprising D-amino acids
EP1112377A4 (de) * 1998-06-22 2004-11-10 Univ California Nukleinsäure-gekoppelte kolorimetrische analytdetektoren
JP2000344685A (ja) * 1999-03-26 2000-12-12 Bf Kenkyusho:Kk アズールa類似化合物によるアミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物
US6399314B1 (en) * 1999-12-29 2002-06-04 American Cyanamid Company Methods of detection of amyloidogenic proteins
AU6299401A (en) * 2000-05-08 2001-11-20 Qtl Biosystems Llc Improvements to the fluorescent polymer-qtl approach to biosensing
JP2002275099A (ja) * 2001-03-16 2002-09-25 Bf Kenkyusho:Kk ベンゾシアゾリン環またはベンゾオキサゾリン環を含む化合物による、アミロイドが蓄積する疾患の画像診断プローブおよびそれを含む画像診断用組成物
US7083928B2 (en) 2001-04-05 2006-08-01 Infectio Diagnostic (I.D.I.), Inc. Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
SE0201468D0 (sv) * 2002-05-13 2002-05-13 Peter Aasberg Metod att använda luminescenta polymerer för detektion av biospecifik växelverkan

Also Published As

Publication number Publication date
CA2608177A1 (en) 2005-11-17
JP4777979B2 (ja) 2011-09-21
AU2005241371A1 (en) 2005-11-17
JP2007536555A (ja) 2007-12-13
US20080038751A1 (en) 2008-02-14
EP1766410A1 (de) 2007-03-28
EP1766410B1 (de) 2010-11-24
WO2005109005A1 (en) 2005-11-17
DE602005024962D1 (de) 2011-01-05
AU2005241371B2 (en) 2010-09-09
ATE489630T1 (de) 2010-12-15
CA2608177C (en) 2013-06-25
US7867718B2 (en) 2011-01-11
NZ551781A (en) 2010-07-30

Similar Documents

Publication Publication Date Title
SE0401219D0 (sv) Metoder för detektera konformationsförändringar eller aggregering hos proteiner med hjälp av konjugerade polyelektrolyter
WO2008030973A3 (en) Methods and compositions for the detection of protein folding disorders
FR2889416B1 (fr) Composition de proteines de pois
WO2009126380A3 (en) Methods and compositions for highly sensitive detection of molecules
DE502004002427D1 (de) Messeinrichtung zur Messung von Inhaltsstoffen in Erntegut
EP1700912A4 (de) Verfahren zum nachweis eines zielmoleküls unter verwendung eines aptamers
EP2211889A4 (de) Antikörpervermittelte unterbrechung von quorum sensing bei bakterien
ATE468755T1 (de) Verfahren und zusammensetzungen mit molkeproteinisolaten
ATE366321T1 (de) Nachweis von sondenmolekülen, die auf einen aktiven bereich eines sensors gebunden sind
WO2014207049A3 (de) Verfahren zur bestimmung von proteinaggregaten unter verwendung von oberflächen-fida
DE602007012439D1 (de) Homogener doppelrezeptor-agglutinationstest für immunsuppressiva
EP1728079A4 (de) Verfahren und biochips zum nachweis kleiner molekülverbindungen
BR112013032803A8 (pt) "derivados de n-[(1h-pirazol-1-il)aril]-1h-indol ou 1h-indazol-3-carboxamida, sua preparação e aplicação dos mesmos em terapêuticos"
GB201106065D0 (en) Sensor readout with redundancy-checking
FR2900734B1 (fr) Detection des maladies veineuses thromboemboliques par le dosage des d-dimeres et de la fibrine soluble
ATE471512T1 (de) Verwendung des proteins s100a 12 als marker für kolorektalkarzinom
DE602006004034D1 (de) Einrichtung zur kraftmessung durch resistive detektion mit doppelter wheatstonebrücke
EP1853915A4 (de) Verfahren zum nachweis falsch gefalteter proteine und prionen
WO2007011746A3 (en) Highly sensitive immunoassays and antibodies for detection of blood factor viii
EP2046998A4 (de) Molekulare biosensoren zum nachweis von makromolekülen und anderen analyten
WO2011109112A3 (en) Method of detecting tau protein and tau fragments in serum
FR2869323B1 (fr) Utilisation du gene codant la chaine beta de la proteine c4bp dans la production de proteines dimeriques recombinantes
DE602004017317D1 (de) Verwendung der proteine proteinase 3 (prn3) und leukozyten elastatse inhibitor (ileu) als marker für kolorektale karzinome
ATE353544T1 (de) Verwendung des proteins masp als marker für kolorektale karzinome
WO2008120263A3 (en) Prokineticins receptors antagonists, derivatives and uses thereof