ATE491022T1 - Konditionell immortalisierte adulte langzeit- stammzellen und verfahren zur herstellung und verwendung von solchen zellen - Google Patents

Konditionell immortalisierte adulte langzeit- stammzellen und verfahren zur herstellung und verwendung von solchen zellen

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Publication number
ATE491022T1
ATE491022T1 AT06826025T AT06826025T ATE491022T1 AT E491022 T1 ATE491022 T1 AT E491022T1 AT 06826025 T AT06826025 T AT 06826025T AT 06826025 T AT06826025 T AT 06826025T AT E491022 T1 ATE491022 T1 AT E491022T1
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Austria
Prior art keywords
cells
methods
stem cells
production
conditionally immortalized
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AT06826025T
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English (en)
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John Cambier
Yosef Refaeli
Sara Johnson
Brian Curtis Turner
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Nat Jewish Health
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Publication of ATE491022T1 publication Critical patent/ATE491022T1/de

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0635—B lymphocytes
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
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    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C12N15/09—Recombinant DNA-technology
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
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  • Toxicology (AREA)
  • Virology (AREA)
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  • Diabetes (AREA)
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AT06826025T 2005-10-18 2006-10-18 Konditionell immortalisierte adulte langzeit- stammzellen und verfahren zur herstellung und verwendung von solchen zellen ATE491022T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72813105P 2005-10-18 2005-10-18
US76599306P 2006-02-06 2006-02-06
PCT/US2006/040379 WO2007047583A2 (en) 2005-10-18 2006-10-18 Conditionally immortalized long-term stem cells and methods of making and using such cells

Publications (1)

Publication Number Publication Date
ATE491022T1 true ATE491022T1 (de) 2010-12-15

Family

ID=37963171

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06826025T ATE491022T1 (de) 2005-10-18 2006-10-18 Konditionell immortalisierte adulte langzeit- stammzellen und verfahren zur herstellung und verwendung von solchen zellen

Country Status (12)

Country Link
US (7) US8883507B2 (de)
EP (1) EP1942739B1 (de)
JP (8) JP2009511081A (de)
KR (2) KR101441843B1 (de)
CN (2) CN105483088B (de)
AT (1) ATE491022T1 (de)
AU (1) AU2006304392B2 (de)
CA (2) CA2626525C (de)
DE (1) DE602006018768D1 (de)
IL (7) IL296832A (de)
IN (1) IN2014DN06624A (de)
WO (1) WO2007047583A2 (de)

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EP3978928A1 (de) 2008-11-14 2022-04-06 The Brigham and Women's Hospital, Inc. Therapeutische und diagnostische verfahren im zusammenhang mit krebsstammzellen
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WO2014130518A1 (en) 2013-02-19 2014-08-28 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
US10272115B2 (en) * 2013-03-11 2019-04-30 Taiga Biotechnologies, Inc. Production and use of red blood cells
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WO2015020993A2 (en) * 2013-08-05 2015-02-12 The Trustees Of The University Of Pennsylvania RNAi COMPOSITIONS AND METHODS FOR TREATMENT OF FRIEDREICH'S ATAXIA
CN103509101B (zh) * 2013-08-12 2016-11-02 中国科学院广州生物医药与健康研究院 一种扩增脐带血造血干细胞的细胞因子及其培养基
WO2016149672A1 (en) 2015-03-18 2016-09-22 The Regents Of The University Of California Methods of preventing and reversing stem cell aging
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US20150240205A1 (en) 2015-08-27
KR20130131488A (ko) 2013-12-03
KR101441843B1 (ko) 2014-09-17
IL278426B (en) 2021-09-30
AU2006304392A1 (en) 2007-04-26
JP6302356B2 (ja) 2018-03-28
US10760055B2 (en) 2020-09-01
HK1222890A1 (zh) 2017-07-14
US20200308545A1 (en) 2020-10-01
CN105483088A (zh) 2016-04-13
EP1942739A2 (de) 2008-07-16
AU2006304392B2 (en) 2014-05-01
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US20220145253A1 (en) 2022-05-12
AU2006304392A8 (en) 2008-05-29
HK1126623A1 (zh) 2009-09-11
US9150831B2 (en) 2015-10-06
JP2009511081A (ja) 2009-03-19
KR20080070005A (ko) 2008-07-29
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IL190946A (en) 2016-09-29
IL286053A (en) 2021-10-31
US20100297763A1 (en) 2010-11-25
IL266009B (en) 2021-06-30
JP2016129515A (ja) 2016-07-21
IL296832A (en) 2022-11-01
KR101441693B1 (ko) 2014-09-25
CN101330830B (zh) 2016-01-20
JP2013017486A (ja) 2013-01-31
WO2007047583A2 (en) 2007-04-26
CN105483088B (zh) 2021-05-28
JP2017221219A (ja) 2017-12-21
IL256512B (en) 2019-05-30
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