ATE491026T1 - Ply-gbs-lysinmutanten - Google Patents

Ply-gbs-lysinmutanten

Info

Publication number
ATE491026T1
ATE491026T1 AT06813511T AT06813511T ATE491026T1 AT E491026 T1 ATE491026 T1 AT E491026T1 AT 06813511 T AT06813511 T AT 06813511T AT 06813511 T AT06813511 T AT 06813511T AT E491026 T1 ATE491026 T1 AT E491026T1
Authority
AT
Austria
Prior art keywords
gbs
plygbs
streptococci
lysins
bacteria
Prior art date
Application number
AT06813511T
Other languages
English (en)
Inventor
Vincent Fischetti
Qi Cheng
Original Assignee
Univ Rockefeller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rockefeller filed Critical Univ Rockefeller
Application granted granted Critical
Publication of ATE491026T1 publication Critical patent/ATE491026T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT06813511T 2005-08-24 2006-08-17 Ply-gbs-lysinmutanten ATE491026T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71093605P 2005-08-24 2005-08-24
PCT/US2006/032176 WO2007024628A2 (en) 2005-08-24 2006-08-17 Ply-gbs mutant lysins

Publications (1)

Publication Number Publication Date
ATE491026T1 true ATE491026T1 (de) 2010-12-15

Family

ID=37772174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06813511T ATE491026T1 (de) 2005-08-24 2006-08-17 Ply-gbs-lysinmutanten

Country Status (9)

Country Link
US (1) US8105585B2 (de)
EP (2) EP2360248A1 (de)
JP (1) JP2009506033A (de)
CN (1) CN101297034A (de)
AT (1) ATE491026T1 (de)
CA (1) CA2620903A1 (de)
DE (1) DE602006018746D1 (de)
ES (1) ES2357626T3 (de)
WO (1) WO2007024628A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8389469B2 (en) * 2005-06-06 2013-03-05 The Rockefeller University Bacteriophage lysins for Bacillus anthracis
ES2357626T3 (es) 2005-08-24 2011-04-28 The Rockefeller University Lisinas mutantes de ply-gbs.
CA2984933C (en) * 2008-07-03 2020-07-07 The Rockefeller University A chimeric bacteriophage lysin with activity against staphylococci bacteria
CN115887627A (zh) 2011-04-21 2023-04-04 洛克菲勒大学 用于革兰氏阳性菌检测和治疗的链球菌属细菌噬菌体溶素
DK2764093T3 (en) 2011-10-05 2018-07-30 Univ Rockefeller DIMER BACTERYPHAGE LYSINES
CN102516398B (zh) * 2011-12-27 2014-07-16 中国科学院遗传与发育生物学研究所 抗乳房炎转基因小鼠模型的构建方法及其专用载体
HK1211484A1 (en) 2012-05-09 2016-05-27 Contrafect Corporation Bacteriophage lysin and antibiotic combinations against gram positive bacteria
KR20200023521A (ko) 2012-05-09 2020-03-04 콘트라펙트 코포레이션 박테리오파지 리신을 이용한 생물막의 예방, 붕괴 및 치료
DE102013106455A1 (de) 2013-06-20 2014-12-24 Airbus Defence and Space GmbH Verfahren zur Dekontamination von bakteriologischen Verunreinigungen
WO2017197227A1 (en) 2016-05-12 2017-11-16 Contrafect Corporation Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides
CN107083434B (zh) * 2017-06-05 2020-09-08 武汉赛思锐微生物技术有限公司 一种非诊断目的的荧光pcr定量检测b族链球菌的样本前处理方法
US20210361696A1 (en) * 2017-06-16 2021-11-25 Boris Farber Biologically active combinatorial polysaccharide derivatives
EP3771463A1 (de) * 2019-07-29 2021-02-03 Ludwig-Maximilians-Universität München Stabilisierung therapeutischer proteine mit piperazin- oder morpholinhaltigen zwitterionischen puffersubstanzen
CN112501189A (zh) * 2020-12-30 2021-03-16 吉林大学 一种能杀死马链球菌马亚种的裂解酶及其医用用途
KR102713606B1 (ko) * 2022-07-26 2024-10-10 주식회사 인트론바이오테크놀로지 젖소유방염 치료용 항균단백질 조성물

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US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
EP0163696B1 (de) 1983-11-14 1992-11-25 Columbia Laboratories, Inc. Verwendung eines bioadhesives
US4496689A (en) 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
DE3590766T (de) 1985-03-30 1987-04-23
EP0206448B1 (de) 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hämoglobin, das an ein Poly(alkenylenoxid) gebunden ist
US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
JPS63502716A (ja) 1986-03-07 1988-10-13 マサチューセッツ・インステチュート・オブ・テクノロジー 糖タンパク安定性の強化方法
US4791192A (en) 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US4948580A (en) 1988-12-08 1990-08-14 E. R. Squibb & Sons, Inc. Muco-bioadhesive composition
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
JPH02258718A (ja) 1989-03-31 1990-10-19 Nippon Kayaku Co Ltd ペースト状基剤及び製剤
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DK0674506T3 (da) 1992-12-02 2001-01-08 Alkermes Inc Væksthormonholdige mikrosfærer med styret frigivelse
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US5554380A (en) 1994-08-04 1996-09-10 Kv Pharmaceutical Company Bioadhesive pharmaceutical delivery system
AU695323B2 (en) 1994-09-09 1998-08-13 Takeda Chemical Industries Ltd. Sustained release preparation containing metal salt of a peptide
PT831787E (pt) 1995-06-07 2002-02-28 Alkermes Inc Composicao para libertacao sustentada da hormona de crescimento humano
ZA965368B (en) 1995-07-14 1997-01-14 Novo Nordisk As A pharmaceutical formulation
US5863560A (en) 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
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US6056954A (en) 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US6056955A (en) 1999-09-14 2000-05-02 Fischetti; Vincent Topical treatment of streptococcal infections
EP1501925A4 (de) 2002-05-17 2006-10-25 New Horizons Diagnostics Corp Identifizierung eines phagenassoziierten lytischen enzyms zum schnellen und spezifischen nachweisen und abtöten von bacillus anthracis
AU2003273257A1 (en) * 2002-08-29 2004-03-19 The Uab Research Foundation Group b streptococcal phage lysin
US7569223B2 (en) 2004-03-22 2009-08-04 The Rockefeller University Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
WO2005089527A2 (en) 2004-03-24 2005-09-29 The Rockefeller University Lytic enzymes and spore surface antigen for detection and treatment of bacillus anthracis bacteria and spores
US7582291B2 (en) 2005-06-30 2009-09-01 The Rockefeller University Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
ES2357626T3 (es) 2005-08-24 2011-04-28 The Rockefeller University Lisinas mutantes de ply-gbs.
CA2984933C (en) 2008-07-03 2020-07-07 The Rockefeller University A chimeric bacteriophage lysin with activity against staphylococci bacteria

Also Published As

Publication number Publication date
CA2620903A1 (en) 2007-03-01
JP2009506033A (ja) 2009-02-12
DE602006018746D1 (de) 2011-01-20
EP1917355B1 (de) 2010-12-08
EP1917355A4 (de) 2009-05-27
ES2357626T3 (es) 2011-04-28
WO2007024628A3 (en) 2007-06-14
CN101297034A (zh) 2008-10-29
EP1917355A2 (de) 2008-05-07
WO2007024628A2 (en) 2007-03-01
EP2360248A1 (de) 2011-08-24
US20080221035A1 (en) 2008-09-11
US8105585B2 (en) 2012-01-31

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Legal Events

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