ATE491938T1 - Substrat für maldi-tof-ms und massenspektrometrisches verfahren unter verwendung davon - Google Patents

Substrat für maldi-tof-ms und massenspektrometrisches verfahren unter verwendung davon

Info

Publication number
ATE491938T1
ATE491938T1 AT05805348T AT05805348T ATE491938T1 AT E491938 T1 ATE491938 T1 AT E491938T1 AT 05805348 T AT05805348 T AT 05805348T AT 05805348 T AT05805348 T AT 05805348T AT E491938 T1 ATE491938 T1 AT E491938T1
Authority
AT
Austria
Prior art keywords
tof
maldi
plate
substrate
protein
Prior art date
Application number
AT05805348T
Other languages
English (en)
Inventor
Aki Iwasaki
Koji Suzuki
Original Assignee
Japan Science & Tech Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Science & Tech Agency filed Critical Japan Science & Tech Agency
Application granted granted Critical
Publication of ATE491938T1 publication Critical patent/ATE491938T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • G01N33/6851Methods of protein analysis involving laser desorption ionisation mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/02Details
    • H01J49/04Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • H01J49/0409Sample holders or containers
    • H01J49/0418Sample holders or containers for laser desorption, e.g. matrix-assisted laser desorption/ionisation [MALDI] plates or surface enhanced laser desorption/ionisation [SELDI] plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/02Devices for withdrawing samples
    • G01N1/22Devices for withdrawing samples in the gaseous state

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
AT05805348T 2004-10-29 2005-10-28 Substrat für maldi-tof-ms und massenspektrometrisches verfahren unter verwendung davon ATE491938T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004315699 2004-10-29
PCT/JP2005/019900 WO2006046697A1 (ja) 2004-10-29 2005-10-28 Maldi-tof ms用基板及びそれを用いた質量分析方法

Publications (1)

Publication Number Publication Date
ATE491938T1 true ATE491938T1 (de) 2011-01-15

Family

ID=36227937

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05805348T ATE491938T1 (de) 2004-10-29 2005-10-28 Substrat für maldi-tof-ms und massenspektrometrisches verfahren unter verwendung davon

Country Status (6)

Country Link
US (1) US8294090B1 (de)
EP (1) EP1830184B1 (de)
JP (1) JP4649416B2 (de)
AT (1) ATE491938T1 (de)
DE (1) DE602005025401D1 (de)
WO (1) WO2006046697A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4761144B2 (ja) * 2005-04-28 2011-08-31 独立行政法人産業技術総合研究所 質量分析用イオン化基板及び質量分析装置
JP5147307B2 (ja) * 2006-07-11 2013-02-20 キヤノン株式会社 質量分析用基板及び質量分析用基板の製造方法
JP4911704B2 (ja) * 2007-02-16 2012-04-04 学校法人 関西大学 Ldiプレート製造方法
WO2008136058A1 (ja) * 2007-04-25 2008-11-13 Shimadzu Corporation レーザ脱離イオン化用サンプルプレート及び該サンプルプレートを用いた質量分析装置
GB0712795D0 (en) * 2007-07-02 2007-08-08 Ecole Polytechnique Federale De Solid phase extraction and ionization device
US7888127B2 (en) 2008-01-15 2011-02-15 Sequenom, Inc. Methods for reducing adduct formation for mass spectrometry analysis
EP2106858B1 (de) * 2008-03-31 2011-11-02 Sony DADC Austria AG Substrat und Zielplatte
EP2389614A1 (de) * 2009-01-26 2011-11-30 Nanoink, Inc. Herstellung einer homogenen grossflächigen anordnung mit homogenen substraten
US9355826B2 (en) * 2012-02-17 2016-05-31 A School Corporation Kansai University Method for imaging mass analysis using physical vapor deposition of platinum nanoparticles
DE102012011647B4 (de) * 2012-06-08 2020-07-02 Bruker Daltonik Gmbh Analyse von Mikroben aus Mikrokolonien mittels MALDI-Massenspektrometrie
US9305756B2 (en) * 2013-03-13 2016-04-05 Agena Bioscience, Inc. Preparation enhancements and methods of use for MALDI mass spectrometry
WO2018151556A1 (ko) * 2017-02-17 2018-08-23 (주)바이오니아 Maldi 질량분석용 시료 플레이트 및 이의 제조 방법
KR101980863B1 (ko) 2017-02-17 2019-05-23 (주)바이오니아 Maldi 질량분석용 시료 플레이트 및 이의 제조 방법
WO2023234372A1 (ja) * 2022-05-31 2023-12-07 株式会社島津製作所 核酸の質量分析方法
US20250250627A1 (en) * 2022-05-31 2025-08-07 Shimadzu Corporation Method for Nucleic Acid Structure Analysis

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4422049C2 (de) * 1994-06-27 1997-12-11 Meinhard Prof Dr Knoll Ultramikroelektroden- oder Nanoden-Array für chemische und biochemische Analysen sowie Verfahren zu dessen Herstellung
US6123819A (en) * 1997-11-12 2000-09-26 Protiveris, Inc. Nanoelectrode arrays
WO2000070060A1 (en) 1999-05-18 2000-11-23 University Of Iowa Research Foundation Production of complex carbohydrates
JP3548769B2 (ja) 1999-06-29 2004-07-28 旭テクネイオン株式会社 微細で均一な結晶を形成するためのカーボン製支持板及びその応用
US7122790B2 (en) * 2000-05-30 2006-10-17 The Penn State Research Foundation Matrix-free desorption ionization mass spectrometry using tailored morphology layer devices
CA2314398A1 (en) * 2000-08-10 2002-02-10 Edward Shipwash Microarrays and microsystems for amino acid analysis and protein sequencing
JP4361271B2 (ja) * 2000-10-10 2009-11-11 バイオトローブ・インコーポレイテツド アッセイ、合成、および保存用の器具、ならびに、その作製、使用、および操作の方法
US6693187B1 (en) 2000-10-17 2004-02-17 Lievre Cornu Llc Phosphinoamidite carboxlates and analogs thereof in the synthesis of oligonucleotides having reduced internucleotide charge
US6825477B2 (en) * 2001-02-28 2004-11-30 Jan Sunner Method and apparatus to produce gas phase analyte ions
DE10112387B4 (de) * 2001-03-15 2004-03-25 Bruker Daltonik Gmbh Massenspektrometrische Genotypisierung
DE10144250A1 (de) * 2001-08-31 2003-04-03 Fraunhofer Ges Forschung Verbesserte massenspektrometrische Analyse unter Verwendung von Nanopartikeln
WO2003038401A2 (en) * 2001-10-31 2003-05-08 The Regents Of The University Of California Semiconductor nanocrystal-based cellular imaging
SE0202398D0 (sv) * 2001-12-11 2002-08-13 Thomas Laurell Target plate and use thereof for improved analysis
DE10164309A1 (de) * 2001-12-28 2003-07-10 Fraunhofer Ges Forschung Verbesserte strukturiert-funktionale Bindematrices für Biomoleküle
JP2003247983A (ja) * 2002-02-25 2003-09-05 Nippon Laser & Electronics Lab 標的物質質量分析システム
US20030220254A1 (en) 2002-03-29 2003-11-27 Texas Tech University System Composition and method for preparation of an oral dual controlled release formulation of a protein and inhibitor
US6900061B2 (en) * 2002-08-23 2005-05-31 Perseptive Biosystems, Inc. MALDI plate and process for making a MALDI plate
JP2004125785A (ja) * 2002-09-02 2004-04-22 National Food Research Institute ビオチン化タンパク質を用いる受容体チップおよびその作製方法
US20040209294A1 (en) 2002-09-02 2004-10-21 National Food Research Institute Method to produce a receptor chip using biotinylated protein
JP4052094B2 (ja) * 2002-11-11 2008-02-27 株式会社島津製作所 レーザー脱離イオン化質量分析における試料作成方法とそれに用いるサンプルプレート
US7105809B2 (en) * 2002-11-18 2006-09-12 3M Innovative Properties Company Microstructured polymeric substrate
JP3915677B2 (ja) * 2002-11-29 2007-05-16 日本電気株式会社 質量分析用チップおよびこれを用いたレーザー脱離イオン化飛行時間型質量分析装置、質量分析システム
JP3975273B2 (ja) 2003-02-28 2007-09-12 国立大学法人 奈良先端科学技術大学院大学 共有結合により固定化されたポルフィリン多量体を基板上に積層させた光機能分子素子及びその製造方法
JP2006521567A (ja) * 2003-03-26 2006-09-21 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 質量分析法を用いる、タンパク質および/または他の分子の測定
WO2005005679A2 (en) * 2003-04-28 2005-01-20 Nanosys, Inc. Super-hydrophobic surfaces, methods of their construction and uses therefor
WO2005027731A2 (en) * 2003-09-19 2005-03-31 University Of Rochester Biagnostic system for otolaryngologic pathogens and use thereof
US7598033B2 (en) * 2003-12-15 2009-10-06 University Of Pennsylvania Method and devices for running reactions on a target plate for MALDI mass spectrometry
RU2361193C2 (ru) * 2004-05-19 2009-07-10 Вп Холдинг, Ллс Оптический датчик с многослойной плазмонной структурой для усовершенствованного обнаружения химических групп посредством sers
EP1804958A4 (de) * 2004-09-17 2010-11-17 Nanosys Inc Nanostrukturierte dünnfilme und ihre verwendung
JP4761144B2 (ja) * 2005-04-28 2011-08-31 独立行政法人産業技術総合研究所 質量分析用イオン化基板及び質量分析装置

Also Published As

Publication number Publication date
WO2006046697A1 (ja) 2006-05-04
DE602005025401D1 (de) 2011-01-27
US8294090B1 (en) 2012-10-23
EP1830184B1 (de) 2010-12-15
JP4649416B2 (ja) 2011-03-09
EP1830184A4 (de) 2008-09-24
EP1830184A1 (de) 2007-09-05
JPWO2006046697A1 (ja) 2008-08-07

Similar Documents

Publication Publication Date Title
ATE491938T1 (de) Substrat für maldi-tof-ms und massenspektrometrisches verfahren unter verwendung davon
WO2004072228A3 (en) Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
DK2253718T3 (da) Fast overflade til biomolekylafgivelse og analyse med høj omsætning
WO2006078289A3 (en) Bio-barcode based detection of target analytes
WO2005003394A3 (en) Bio-barcode based detection of target analytes
ATE417273T1 (de) Proteinphosphorylierung bei grosszellig- anaplastischem lymphom
DE602005023260D1 (de) Markierungsreagentien, markierte analyten, einschliesslich mischungen davon, und davon abgeleitete fragmentionen und verfahren zu deren analyse
ATE335836T1 (de) Verfahren und kit zum nachweis von betalactam enthaltenden verbindungen
WO2006078660A3 (en) Nucleic acid enzyme ligation sensor
WO2007133704A3 (en) A non-nucleic acid based biobarcode assay for detection of biological materials
DE60230660D1 (de) Verfahren zur kontrolle von polypeptidproduktion udesorption/ionisations massenspektrometrie
WO2009094784A8 (en) High-throughput screening of metabolic disorders using a laser desorption ion source coupled to a mass analyzer
WO2006000576A3 (en) Methods and compositions to promote bone homeostasis
ATE519116T1 (de) Verfahren zur normierung der konzentration von analyten in einer urinprobe
WO2004088325A3 (en) Determination of proteins and/or other molecules using mass spectroscopy
AU2003296424A1 (en) Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders
EP1891433A4 (de) Verfahren zur klassifizierung chemisch quervernetzter zellulärer proben unter verwendung von massenspektren
WO2009011426A1 (ja) γ-セクレターゼの新規基質c-Metを利用したスクリーニング方法
EA202190693A1 (ru) Способы анализа масс-спектрометрии композиций модифицированных клеток
WO2009064006A1 (ja) γ-セクレターゼの新規基質EphA7を利用したスクリーニング方法
DE60236530D1 (de) Verfahren zur vorbehandlung von proben zur bestimmung von verzuckerten aminen, sowie verfahren zur bestimmung von verzuckerten aminen
WO2012097276A3 (en) Bcl-2-like protein 11 srm/mrm assay
Leite et al. Removal of sodium and potassium adducts using a matrix additive during matrix‐associated laser desorption/ionization time‐of‐flight mass spectrometric analysis of peptides
WO2006132797A3 (en) Preparation of small liquid samples for automated analysis
Arsene et al. High sensitivity mass spectrometric quantification of serum growth hormone by amphiphilic peptide conjugation

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties