ATE49217T1 - Verfahren zur herstellung von steroidderivaten mit verringerter teilchengroesse. - Google Patents

Verfahren zur herstellung von steroidderivaten mit verringerter teilchengroesse.

Info

Publication number
ATE49217T1
ATE49217T1 AT84307432T AT84307432T ATE49217T1 AT E49217 T1 ATE49217 T1 AT E49217T1 AT 84307432 T AT84307432 T AT 84307432T AT 84307432 T AT84307432 T AT 84307432T AT E49217 T1 ATE49217 T1 AT E49217T1
Authority
AT
Austria
Prior art keywords
particle size
compound
reduced particle
preparation
steroid derivatives
Prior art date
Application number
AT84307432T
Other languages
English (en)
Inventor
Derek Charles Riley
David Johnston
Original Assignee
Sterwin Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterwin Ag filed Critical Sterwin Ag
Application granted granted Critical
Publication of ATE49217T1 publication Critical patent/ATE49217T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0036—Nitrogen-containing hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
AT84307432T 1983-10-29 1984-10-29 Verfahren zur herstellung von steroidderivaten mit verringerter teilchengroesse. ATE49217T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB838328929A GB8328929D0 (en) 1983-10-29 1983-10-29 Steroid compounds
EP84307432A EP0142309B1 (de) 1983-10-29 1984-10-29 Verfahren zur Herstellung von Steroidderivaten mit verringerter Teilchengrösse

Publications (1)

Publication Number Publication Date
ATE49217T1 true ATE49217T1 (de) 1990-01-15

Family

ID=10550923

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84307432T ATE49217T1 (de) 1983-10-29 1984-10-29 Verfahren zur herstellung von steroidderivaten mit verringerter teilchengroesse.

Country Status (11)

Country Link
US (1) US4605517A (de)
EP (1) EP0142309B1 (de)
AT (1) ATE49217T1 (de)
DE (1) DE3480929D1 (de)
DK (1) DK511184A (de)
ES (1) ES537181A0 (de)
FI (1) FI81362C (de)
GB (2) GB8328929D0 (de)
GR (1) GR80795B (de)
NO (1) NO159385C (de)
PT (1) PT79423B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5995300A (ja) 1982-11-02 1984-06-01 スタ−リング・ドラッグ・インコ−ポレ−テッド コントロ−ルされた粒度の２−シアノ−４，５−エポキシ−３−オキソ−ステロイド類およびそれらの組成物
US6458811B1 (en) * 1996-03-26 2002-10-01 Eli Lilly And Company Benzothiophenes formulations containing same and methods
ATE399554T1 (de) 1999-08-03 2008-07-15 Lilly Icos Llc Pharmazeutische zusammensetzung enthaltend tadalafil
GB2375958B (en) * 2001-04-09 2005-03-02 George Margetts The use of steroids to lower the levels of cortisol
CN100404545C (zh) * 2003-03-27 2008-07-23 尼科梅德有限责任公司 具有规定粒径的结晶环缩松的制备方法
MY143936A (en) * 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
GB2400554B (en) * 2003-04-16 2007-04-18 George Margetts Treatment of angiotensin II-induced cardiovascular disease
GB2414238B (en) * 2004-05-22 2006-12-13 Stegram Pharmaceuticals Ltd Method for the preparation of trilostane
JP5508003B2 (ja) 2006-06-30 2014-05-28 アイスイティカ ピーティーワイ リミテッド ナノ粒子状の形態における生物学的に活性な化合物の調製のための方法
CN111684129A (zh) 2017-12-04 2020-09-18 纳诺洛斯有限公司 由微生物纤维素生产粘胶原液的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB911814A (en) * 1958-03-24 1962-11-28 Sterling Drug Inc Steroid compounds and preparation thereof
NL241544A (de) * 1958-07-23
NO122525B (de) * 1960-11-23 1971-07-12 Merck & Co Inc
GB1123770A (en) * 1966-11-15 1968-08-14 Sterling Drug Inc 2-cyano-3-oxo-steroids
US4277409A (en) * 1977-03-18 1981-07-07 Roussel Uclaf Preparation of 9α-fluoro-16α-methyl-21-acetoxy-Δ1,4 -pregnadiene-11β-ol-3,20-dione
US4160027A (en) * 1977-12-20 1979-07-03 Sterling Drug Inc. Steroid cyanoketones and intermediates
US4391755A (en) * 1982-01-18 1983-07-05 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method
JPS5995300A (ja) * 1982-11-02 1984-06-01 スタ−リング・ドラッグ・インコ−ポレ−テッド コントロ−ルされた粒度の２−シアノ−４，５−エポキシ−３−オキソ−ステロイド類およびそれらの組成物
US4459235A (en) * 1983-03-03 1984-07-10 G. D. Searle & Co. 2-Cyanosteroids

Also Published As

Publication number Publication date
FI844238A0 (fi) 1984-10-29
EP0142309A3 (en) 1986-02-12
PT79423A (en) 1984-11-01
GB8328929D0 (en) 1983-11-30
DE3480929D1 (de) 1990-02-08
DK511184D0 (da) 1984-10-26
GB2148899B (en) 1987-07-22
ES8603509A1 (es) 1985-12-16
EP0142309B1 (de) 1990-01-03
FI81362C (fi) 1990-10-10
ES537181A0 (es) 1985-12-16
GR80795B (en) 1985-03-01
FI81362B (fi) 1990-06-29
US4605517A (en) 1986-08-12
GB8427300D0 (en) 1984-12-05
PT79423B (en) 1986-11-13
NO159385C (no) 1988-12-21
EP0142309A2 (de) 1985-05-22
FI844238L (fi) 1985-04-30
GB2148899A (en) 1985-06-05
NO159385B (no) 1988-09-12
DK511184A (da) 1985-04-30
NO844300L (no) 1985-04-30

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