ATE493127T1 - Verwendung von levo-ornidazol zur herstellung eines antiparasitären infektionswirkstoffs - Google Patents
Verwendung von levo-ornidazol zur herstellung eines antiparasitären infektionswirkstoffsInfo
- Publication number
- ATE493127T1 ATE493127T1 AT06742090T AT06742090T ATE493127T1 AT E493127 T1 ATE493127 T1 AT E493127T1 AT 06742090 T AT06742090 T AT 06742090T AT 06742090 T AT06742090 T AT 06742090T AT E493127 T1 ATE493127 T1 AT E493127T1
- Authority
- AT
- Austria
- Prior art keywords
- ornidazole
- levo
- preparation
- antiparasic
- producing
- Prior art date
Links
- IPWKIXLWTCNBKN-ZCFIWIBFSA-N (2s)-1-chloro-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol Chemical compound CC1=NC=C([N+]([O-])=O)N1C[C@H](O)CCl IPWKIXLWTCNBKN-ZCFIWIBFSA-N 0.000 title abstract 2
- 239000012678 infectious agent Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 abstract 5
- 229940079593 drug Drugs 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 229960002313 ornidazole Drugs 0.000 abstract 3
- 208000030852 Parasitic disease Diseases 0.000 abstract 2
- 230000002141 anti-parasite Effects 0.000 abstract 2
- 239000003096 antiparasitic agent Substances 0.000 abstract 2
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 241000224489 Amoeba Species 0.000 abstract 1
- 241000224527 Trichomonas vaginalis Species 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100835172A CN1305469C (zh) | 2005-07-08 | 2005-07-08 | 左旋奥硝唑在制备抗寄生虫感染的药物中的应用 |
| PCT/CN2006/001204 WO2007006197A1 (fr) | 2005-07-08 | 2006-06-05 | Utilisation de lévo-ornidazole pour la préparation de médicaments contre les infections parasitaires |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE493127T1 true ATE493127T1 (de) | 2011-01-15 |
Family
ID=35705578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06742090T ATE493127T1 (de) | 2005-07-08 | 2006-06-05 | Verwendung von levo-ornidazol zur herstellung eines antiparasitären infektionswirkstoffs |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080177083A1 (de) |
| EP (1) | EP1902712B1 (de) |
| CN (1) | CN1305469C (de) |
| AT (1) | ATE493127T1 (de) |
| DE (1) | DE602006019250D1 (de) |
| ES (1) | ES2358441T3 (de) |
| WO (1) | WO2007006197A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100451023C (zh) * | 2006-01-06 | 2009-01-14 | 陕西新安医药科技有限公司 | 左旋奥硝唑磷酸酯及其制备方法和用途 |
| CN1329379C (zh) * | 2006-01-06 | 2007-08-01 | 沈阳中海生物技术开发有限公司 | 抗厌氧菌化合物 |
| CN100534429C (zh) * | 2006-05-12 | 2009-09-02 | 南京圣和药业有限公司 | 左旋奥硝唑阴道给药制剂及其制备方法和制药用途 |
| CN100503606C (zh) * | 2006-05-24 | 2009-06-24 | 沈阳中海生物技术开发有限公司 | 噻二唑取代的咪唑类抗厌氧菌化合物 |
| CN100387233C (zh) * | 2006-06-09 | 2008-05-14 | 南京圣和药业有限公司 | 左旋吗啉硝唑在制备抗寄生虫感染药物中的用途 |
| CN102813622B (zh) * | 2012-08-09 | 2013-06-26 | 西安万隆制药股份有限公司 | 一种奥硝唑氯化钠注射液组合物 |
| EP3244890B1 (de) | 2014-12-20 | 2025-05-21 | Gregg, John Malcolm Hall | Ornidazol zur behandlung von infektionen verursacht durch burkholderia mallei oder burkholderia pseudomallei |
| US20210369675A1 (en) * | 2016-08-20 | 2021-12-02 | John Malcolm Hall Gregg | Antimicrobial drug methods of use & therapeutic compositions |
| CN114478392B (zh) * | 2020-10-26 | 2023-09-29 | 南京锐志生物医药有限公司 | 一种抗厌氧菌化合物的酯类前药、药物组合物及其制备方法和应用 |
| CN114452315B (zh) * | 2022-03-16 | 2023-04-07 | 郑州大学第一附属医院 | 一种阴道泡腾栓及其制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3435049A (en) * | 1965-05-19 | 1969-03-25 | Hoffmann La Roche | Nitroimidazole derivatives |
| US4289751A (en) * | 1979-06-29 | 1981-09-15 | Merck & Co., Inc. | Effervescent enteric-coated formulation of soluble form of erythromycin and therapeutic use thereof |
| CS237849B1 (sk) * | 1984-01-09 | 1985-10-16 | Marian Simko | Dopravné zariadenie, najma pre dopravu foriem vo vypeňovacej linke |
| MX9304399A (es) * | 1992-07-31 | 1994-02-28 | Warner Lambert Co | Proceso novedoso para preparar [[2-bromoetil)-amino]metil]-2-nitro-1h-imidazol-1-etanol quiral y compuestos relacionados. |
| US6576250B1 (en) * | 1998-03-27 | 2003-06-10 | Cima Labs Inc. | Pharmaceutical compositions for rectal and vaginal administration |
| CN1179951C (zh) * | 2002-07-19 | 2004-12-15 | 中国科学院上海有机化学研究所 | 噻克硝唑的光学对映体、制备方法及其用途 |
| CN1212405C (zh) * | 2002-08-23 | 2005-07-27 | 中国科学院上海有机化学研究所 | 外消旋奥硝唑的酶法拆分方法 |
| CN1332662C (zh) * | 2005-04-29 | 2007-08-22 | 南京圣和药业有限公司 | 左旋奥硝唑的静脉给药制剂及其制备方法 |
-
2005
- 2005-07-08 CN CNB2005100835172A patent/CN1305469C/zh not_active Expired - Lifetime
-
2006
- 2006-06-05 US US11/909,623 patent/US20080177083A1/en not_active Abandoned
- 2006-06-05 ES ES06742090T patent/ES2358441T3/es active Active
- 2006-06-05 EP EP06742090A patent/EP1902712B1/de not_active Not-in-force
- 2006-06-05 AT AT06742090T patent/ATE493127T1/de not_active IP Right Cessation
- 2006-06-05 DE DE602006019250T patent/DE602006019250D1/de active Active
- 2006-06-05 WO PCT/CN2006/001204 patent/WO2007006197A1/zh not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1902712B1 (de) | 2010-12-29 |
| CN1709245A (zh) | 2005-12-21 |
| WO2007006197A1 (fr) | 2007-01-18 |
| EP1902712A1 (de) | 2008-03-26 |
| US20080177083A1 (en) | 2008-07-24 |
| CN1305469C (zh) | 2007-03-21 |
| DE602006019250D1 (de) | 2011-02-10 |
| EP1902712A4 (de) | 2008-09-10 |
| ES2358441T3 (es) | 2011-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |