ATE493421T1 - Neue inhibitoren von chymase - Google Patents

Neue inhibitoren von chymase

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Publication number
ATE493421T1
ATE493421T1 AT05711644T AT05711644T ATE493421T1 AT E493421 T1 ATE493421 T1 AT E493421T1 AT 05711644 T AT05711644 T AT 05711644T AT 05711644 T AT05711644 T AT 05711644T AT E493421 T1 ATE493421 T1 AT E493421T1
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Austria
Prior art keywords
chymase
new inhibitors
inhibitors
new
Prior art date
Application number
AT05711644T
Other languages
English (en)
Inventor
Michael Hawkins
Michael Greco
Eugene Powell
Garavilla Lawrence De
Bruce Maryanoff
Original Assignee
Janssen Pharmaceutica Nv
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Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
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Publication of ATE493421T1 publication Critical patent/ATE493421T1/de

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    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
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AT05711644T 2004-01-23 2005-01-18 Neue inhibitoren von chymase ATE493421T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53866304P 2004-01-23 2004-01-23
PCT/US2005/001659 WO2005073214A2 (en) 2004-01-23 2005-01-18 Novel inhibitors of chymase

Publications (1)

Publication Number Publication Date
ATE493421T1 true ATE493421T1 (de) 2011-01-15

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AT05711644T ATE493421T1 (de) 2004-01-23 2005-01-18 Neue inhibitoren von chymase

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US (2) US7459444B2 (de)
EP (1) EP1716160B1 (de)
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JP5404388B2 (ja) * 2006-05-10 2014-01-29 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 冷メントール受容体−１拮抗薬
US8629281B2 (en) 2011-01-14 2014-01-14 Janssen Pharmaceutica, Nv Cold menthol receptor-1 antagonists
JP5117382B2 (ja) 2006-05-31 2013-01-16 第一三共株式会社 ７員環化合物の製造方法
JP4986249B2 (ja) * 2006-10-06 2012-07-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング チマーゼ阻害剤
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FR2934267B1 (fr) * 2008-07-23 2010-08-13 Pharmaleads Derives aminophosphiniques utiles dans le traitement de la douleur
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CN106467515B (zh) * 2015-08-18 2019-09-24 宁波洞密生物科技有限公司 一类6-吡啶苯并咪唑吲哚衍生物及其制备方法与医药领域的应用
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CN108383875B (zh) * 2018-03-22 2020-04-28 昆明学院 一种银催化的3-膦酰甲基吲哚啉及制备方法
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IL177037A (en) 2013-05-30
AR047448A1 (es) 2006-01-18
DE602005025600D1 (de) 2011-02-10
ECSP066721A (es) 2006-10-31
WO2005073214A3 (en) 2005-10-20
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JP2007518807A (ja) 2007-07-12
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CR8563A (es) 2009-01-14
US20050176769A1 (en) 2005-08-11
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KR101182143B1 (ko) 2012-09-13
CN1934120A (zh) 2007-03-21
NO20063647L (no) 2006-10-19
HK1148753A1 (en) 2011-09-16
NZ548684A (en) 2009-04-30
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ES2357013T3 (es) 2011-04-15
EP1716160A2 (de) 2006-11-02
IL177037A0 (en) 2006-12-10
CN1934120B (zh) 2010-05-26
US7459444B2 (en) 2008-12-02
US20090036409A1 (en) 2009-02-05
EA200601358A1 (ru) 2007-02-27
EP1716160B1 (de) 2010-12-29
CA2554205A1 (en) 2005-08-11
CN101863923A (zh) 2010-10-20
AU2005207856A1 (en) 2005-08-11
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AU2005207856B2 (en) 2011-07-14

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