CR8563A - Inhibidores de la quimasa novedosos - Google Patents

Inhibidores de la quimasa novedosos

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Publication number
CR8563A
CR8563A CR8563A CR8563A CR8563A CR 8563 A CR8563 A CR 8563A CR 8563 A CR8563 A CR 8563A CR 8563 A CR8563 A CR 8563A CR 8563 A CR8563 A CR 8563A
Authority
CR
Costa Rica
Prior art keywords
novel
chimase
inhibitors
chimase inhibitors
methods
Prior art date
Application number
CR8563A
Other languages
English (en)
Inventor
J Hawkins Michael
N Greco Michael
Powell Eugene
De Garavilla Lawrence
E Maryanoff Bruce
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CR8563A publication Critical patent/CR8563A/es

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
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    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
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    • C07F9/28—Phosphorus compounds with one or more P—C bonds
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Abstract

La presente invencion esta dirigida a un compuesto de la formula (I) metodos para preparar estos compuestos, composiciones, intermediarios y derivados de los mismos, y metodos para tratar trastornos inflamatorios y mediados por serina proteasa.
CR8563A 2004-01-23 2006-08-14 Inhibidores de la quimasa novedosos CR8563A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53866304P 2004-01-23 2004-01-23

Publications (1)

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CR8563A true CR8563A (es) 2009-01-14

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CR8563A CR8563A (es) 2004-01-23 2006-08-14 Inhibidores de la quimasa novedosos

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US (2) US7459444B2 (es)
EP (1) EP1716160B1 (es)
JP (1) JP5022711B2 (es)
KR (1) KR101182143B1 (es)
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BRPI0718167A2 (pt) * 2006-10-18 2013-11-26 Janssen Pharmaceutica Nv Inibidores de quimase
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CN107573263B (zh) * 2017-08-14 2020-04-07 大连理工大学 一种ω-取代缩二脲类化合物的合成方法
CN108383875B (zh) * 2018-03-22 2020-04-28 昆明学院 一种银催化的3-膦酰甲基吲哚啉及制备方法
CN115873037A (zh) * 2022-11-30 2023-03-31 南通大学 一种膦化氮杂吲哚啉的合成方法

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HK1148753A1 (en) 2011-09-16
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ECSP066721A (es) 2006-10-31
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CA2554205A1 (en) 2005-08-11
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NZ548684A (en) 2009-04-30
CN1934120A (zh) 2007-03-21
EA200601358A1 (ru) 2007-02-27
EP1716160A2 (en) 2006-11-02
JP5022711B2 (ja) 2012-09-12
WO2005073214A3 (en) 2005-10-20
US20050176769A1 (en) 2005-08-11
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MXPA06008375A (es) 2007-03-21
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AR047448A1 (es) 2006-01-18
WO2005073214A2 (en) 2005-08-11
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