ATE493505T1 - Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien - Google Patents

Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien

Info

Publication number
ATE493505T1
ATE493505T1 AT07819552T AT07819552T ATE493505T1 AT E493505 T1 ATE493505 T1 AT E493505T1 AT 07819552 T AT07819552 T AT 07819552T AT 07819552 T AT07819552 T AT 07819552T AT E493505 T1 ATE493505 T1 AT E493505T1
Authority
AT
Austria
Prior art keywords
concentration
measuring
media containing
proteolytic activity
containing cells
Prior art date
Application number
AT07819552T
Other languages
English (en)
Inventor
Peter L Giesen
Kerry Tappenden
Wynne Jones
Original Assignee
Thrombinoscope B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thrombinoscope B V filed Critical Thrombinoscope B V
Application granted granted Critical
Publication of ATE493505T1 publication Critical patent/ATE493505T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT07819552T 2006-11-02 2007-11-02 Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien ATE493505T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06022813 2006-11-02
PCT/EP2007/009528 WO2008052795A1 (en) 2006-11-02 2007-11-02 Method for measuring the concentration of transient proteolytic activity in composite biological media containing cells

Publications (1)

Publication Number Publication Date
ATE493505T1 true ATE493505T1 (de) 2011-01-15

Family

ID=37763889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07819552T ATE493505T1 (de) 2006-11-02 2007-11-02 Verfahren zur messung der konzentration transienter proteolytischer aktivität in zellen enthaltenden zusammengesetzten biologischen medien

Country Status (10)

Country Link
US (1) US8343730B2 (de)
EP (1) EP2087131B1 (de)
JP (1) JP2010508036A (de)
KR (1) KR20090085666A (de)
CN (1) CN101548019A (de)
AT (1) ATE493505T1 (de)
AU (1) AU2007315210A1 (de)
CA (1) CA2668356A1 (de)
DE (1) DE602007011661D1 (de)
WO (1) WO2008052795A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2029768B1 (de) * 2006-06-06 2013-02-13 Thrombinoscope B.V. Verfahren zur bestimmung der thrombinaktivität in plasma
US8343730B2 (en) 2006-11-02 2013-01-01 Thrombinoscope B.V. Method for determining the course of proteolytic activity
ATE516504T1 (de) * 2008-02-07 2011-07-15 Synapse Bv Um den einfluss von störfaktoren korrigierte messung des zeitlichen verlaufs einer enzymatischen aktivität bei der reaktion eines enzyms mit einem substrat
JP5385686B2 (ja) * 2009-06-05 2014-01-08 サントリーホールディングス株式会社 血小板凝集抑制剤
US8293493B2 (en) * 2010-01-27 2012-10-23 Adventist Health System/Sunbelt, Inc. Thrombin generation determination method
US9989532B2 (en) * 2013-07-26 2018-06-05 The University Of North Carolina At Chapel Hill Methods and compositions for detecting coagulation inhibitors
CN104965017B (zh) * 2015-06-17 2017-06-16 广西师范学院 水蛭素抗凝血酶活性的测定方法
EP3388838B1 (de) * 2016-01-29 2022-02-16 Sony Group Corporation Blutgerinnungsanalyse
EP4269605A4 (de) * 2020-12-28 2024-11-20 Fujimori Kogyo Co., Ltd. Blutgerinnungsinspektionsverfahren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052199A1 (en) * 1999-03-04 2000-09-08 Synapse B.V. Determination of biologically active forms of proteolytic enzymes
US6740096B2 (en) * 2002-01-16 2004-05-25 Scimed Life Systems, Inc. Treatment and removal of objects in anatomical lumens
ATE368229T1 (de) * 2002-05-01 2007-08-15 Synapse Bv Diagnostischer test zur bestimmung der konzentration einer transienten proteolytischen aktivität in zusammengesetzten biologischen medien
EP1717588A1 (de) * 2005-04-29 2006-11-02 Synapse B.V. Bestimmung der Thrombinaktivität in Vollblut
EP2029768B1 (de) * 2006-06-06 2013-02-13 Thrombinoscope B.V. Verfahren zur bestimmung der thrombinaktivität in plasma
US8343730B2 (en) 2006-11-02 2013-01-01 Thrombinoscope B.V. Method for determining the course of proteolytic activity

Also Published As

Publication number Publication date
CA2668356A1 (en) 2008-05-08
EP2087131B1 (de) 2010-12-29
CN101548019A (zh) 2009-09-30
EP2087131A1 (de) 2009-08-12
KR20090085666A (ko) 2009-08-07
US8343730B2 (en) 2013-01-01
WO2008052795A1 (en) 2008-05-08
DE602007011661D1 (de) 2011-02-10
US20100105091A1 (en) 2010-04-29
JP2010508036A (ja) 2010-03-18
AU2007315210A1 (en) 2008-05-08

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