ATE495187T1 - Dalda-analoge und ihre verwendung - Google Patents

Dalda-analoge und ihre verwendung

Info

Publication number
ATE495187T1
ATE495187T1 AT00917550T AT00917550T ATE495187T1 AT E495187 T1 ATE495187 T1 AT E495187T1 AT 00917550 T AT00917550 T AT 00917550T AT 00917550 T AT00917550 T AT 00917550T AT E495187 T1 ATE495187 T1 AT E495187T1
Authority
AT
Austria
Prior art keywords
dalda
analogues
management
pain
compounds
Prior art date
Application number
AT00917550T
Other languages
English (en)
Inventor
Peter Schiller
Szeto Hazel
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Application granted granted Critical
Publication of ATE495187T1 publication Critical patent/ATE495187T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Treating Waste Gases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT00917550T 1999-03-16 2000-03-08 Dalda-analoge und ihre verwendung ATE495187T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900961A SE9900961D0 (sv) 1999-03-16 1999-03-16 Novel compounds
PCT/SE2000/000462 WO2000055189A1 (en) 1999-03-16 2000-03-08 Dalda analogs and their use

Publications (1)

Publication Number Publication Date
ATE495187T1 true ATE495187T1 (de) 2011-01-15

Family

ID=20414882

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00917550T ATE495187T1 (de) 1999-03-16 2000-03-08 Dalda-analoge und ihre verwendung

Country Status (8)

Country Link
US (2) US6703483B1 (de)
EP (1) EP1163263B1 (de)
AT (1) ATE495187T1 (de)
AU (1) AU3850600A (de)
CA (1) CA2361364C (de)
DE (1) DE60045508D1 (de)
SE (1) SE9900961D0 (de)
WO (1) WO2000055189A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6541021B1 (en) * 1999-03-18 2003-04-01 Durect Corporation Devices and methods for pain management
US7074803B2 (en) * 2001-03-02 2006-07-11 Durect Corporation Opioid formulations
ATE496533T1 (de) * 2000-07-18 2011-02-15 Cornell Res Foundation Inc Medizinische verwendung von agonisten des mu- opioid rezeptors
US20040102476A1 (en) * 2002-11-25 2004-05-27 Chan Tai Wah High concentration formulations of opioids and opioid derivatives
SI2656854T1 (sl) * 2003-02-04 2015-09-30 Cornell Research Foundation, Inc. Uporabe aromatsko-kationskega peptida
EP3167935B1 (de) 2003-05-01 2018-07-18 Cornell Research Foundation, Inc. Verfahren und trägerkomplexe zur abgabe von molekülen an zellen
CA3024434A1 (en) 2004-01-23 2005-08-11 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
US20050282756A1 (en) * 2004-06-18 2005-12-22 Mehta Nozer M Oral delivery of peptide pharmaceutical compositions
EP3725324A1 (de) * 2005-09-16 2020-10-21 Cornell Research Foundation, Inc. Aromatisch-kationisches peptid zur verwendung in einem verfahren zur reduzierung der cd36-expression
US8093207B2 (en) * 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
EP2712620A1 (de) 2008-02-07 2014-04-02 Cornell University Verfahren zur Vorbeugung oder Behandlung von Insulinresistenz
CN107802821A (zh) 2008-02-26 2018-03-16 康奈尔大学 用于防止和治疗急性肾损伤的方法
EP3563862B1 (de) 2009-03-20 2021-05-05 The General Hospital Corporation d/b/a Massachusetts General Hospital D-arg-2'6'-dimethyltyrosin-lys-phe-nh2 zur verhinderung von sekundären komplikationen von brandverletzungen
CA2770688C (en) * 2009-08-12 2018-06-05 Cornell University Methods for preventing or treating metabolic syndrome
SI3708178T1 (sl) 2009-08-24 2024-01-31 Stealth Biotherapeutics Inc. Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule
EP3603658B1 (de) 2009-10-05 2025-01-08 Cornell University Peptide zur verwendung in der behandlung von herzinsuffizienz verursacht durch hypertrophe cardiomyopathy
EP2808029A3 (de) * 2010-03-15 2015-04-01 Stealth Peptides International, Inc. Kombinationstherapien mit Cyclosporin und aromatischen kationischen Peptiden
US20110245182A1 (en) 2010-04-06 2011-10-06 Perricone Nicholas V Topical Uses of Szeto-Schiller Peptides
US20110245183A1 (en) 2010-04-06 2011-10-06 Perricone Nicholas V Topical Uses of Szeto-Schiller Peptides
US20120083452A1 (en) * 2010-09-30 2012-04-05 Perricone Nicholas V Topical Anesthetic Uses of Szeto-Schiller Peptides
HUE054626T2 (hu) 2014-06-25 2021-09-28 Flamma Spa Eljárás D-arginil-2,6-dimetil-L-tirozil-L-lizil-L-fenilalaninamid elõállítására
PL3160985T3 (pl) 2014-06-30 2021-12-27 Flamma S.P.A. Sposób wytwarzania d-arginylo-2,6-dimetylo-l-tyrozylo-l-lizylo-l-fenyloalaninoamidu
JP6854771B2 (ja) * 2015-03-06 2021-04-07 ステルス バイオセラピューティックス コープ 薬学的に適切なペプチドを調製するための方法
US11034724B2 (en) 2017-04-05 2021-06-15 Stealth Biotherapeutics Corp. Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
US11389431B2 (en) 2020-09-09 2022-07-19 Social Profit Network Methods and compositions for delivery of biotin to mitochondria
CN117881411A (zh) 2021-06-01 2024-04-12 艾迪雅生物有限责任公司 用于眼部药物的延长释放药物递送系统和使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG64368A1 (en) * 1988-06-30 1999-04-27 Astra Ab Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same
US5602100A (en) * 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
IS4261A (is) * 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US5788307A (en) * 1996-08-23 1998-08-04 Gilbert; Louis A. Pickup body protection apparatus
US5885958A (en) * 1997-03-25 1999-03-23 Administrators Of The Tulane Educational Fund Mu-opiate receptor peptides

Also Published As

Publication number Publication date
SE9900961D0 (sv) 1999-03-16
WO2000055189A1 (en) 2000-09-21
DE60045508D1 (de) 2011-02-24
US20040176305A1 (en) 2004-09-09
CA2361364A1 (en) 2000-09-21
US6703483B1 (en) 2004-03-09
CA2361364C (en) 2011-02-15
EP1163263B1 (de) 2011-01-12
EP1163263A1 (de) 2001-12-19
AU3850600A (en) 2000-10-04

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties