ATE496533T1 - Medizinische verwendung von agonisten des mu- opioid rezeptors - Google Patents

Medizinische verwendung von agonisten des mu- opioid rezeptors

Info

Publication number
ATE496533T1
ATE496533T1 AT01955855T AT01955855T ATE496533T1 AT E496533 T1 ATE496533 T1 AT E496533T1 AT 01955855 T AT01955855 T AT 01955855T AT 01955855 T AT01955855 T AT 01955855T AT E496533 T1 ATE496533 T1 AT E496533T1
Authority
AT
Austria
Prior art keywords
amino acid
mammal
opioid receptor
receptor agonists
medical use
Prior art date
Application number
AT01955855T
Other languages
English (en)
Inventor
Hazel Szeto
Peter W Schiller
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Application granted granted Critical
Publication of ATE496533T1 publication Critical patent/ATE496533T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01955855T 2000-07-18 2001-07-18 Medizinische verwendung von agonisten des mu- opioid rezeptors ATE496533T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21904600P 2000-07-18 2000-07-18
PCT/US2001/022563 WO2002005748A2 (en) 2000-07-18 2001-07-18 Medicinal uses of mu-opioid receptor agonists

Publications (1)

Publication Number Publication Date
ATE496533T1 true ATE496533T1 (de) 2011-02-15

Family

ID=22817610

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01955855T ATE496533T1 (de) 2000-07-18 2001-07-18 Medizinische verwendung von agonisten des mu- opioid rezeptors

Country Status (7)

Country Link
US (2) US7498297B2 (de)
EP (1) EP1303186B1 (de)
AT (1) ATE496533T1 (de)
AU (1) AU2001277908A1 (de)
CA (1) CA2416475C (de)
DE (1) DE60143945D1 (de)
WO (1) WO2002005748A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1939529A (zh) * 2002-01-29 2007-04-04 Wyeth公司 用于调节连接蛋白半通道的组合物和方法
SI2656854T1 (sl) * 2003-02-04 2015-09-30 Cornell Research Foundation, Inc. Uporabe aromatsko-kationskega peptida
EP3167935B1 (de) * 2003-05-01 2018-07-18 Cornell Research Foundation, Inc. Verfahren und trägerkomplexe zur abgabe von molekülen an zellen
WO2005015203A2 (en) * 2003-08-06 2005-02-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor mu 1 (oprm1)
CA3024434A1 (en) 2004-01-23 2005-08-11 Cornell Research Foundation, Inc. Methods for reducing oxidative damage
US20050282756A1 (en) * 2004-06-18 2005-12-22 Mehta Nozer M Oral delivery of peptide pharmaceutical compositions
ATE456829T1 (de) * 2004-09-22 2010-02-15 Koninkl Philips Electronics Nv Datenverarbeitungsschaltung mit funktionseinheiten mit gemeinsamen leseports
EP3725324A1 (de) 2005-09-16 2020-10-21 Cornell Research Foundation, Inc. Aromatisch-kationisches peptid zur verwendung in einem verfahren zur reduzierung der cd36-expression
US8093207B2 (en) 2005-12-09 2012-01-10 Unigene Laboratories, Inc. Fast-acting oral peptide pharmaceutical products
EP2712620A1 (de) 2008-02-07 2014-04-02 Cornell University Verfahren zur Vorbeugung oder Behandlung von Insulinresistenz
CN107802821A (zh) 2008-02-26 2018-03-16 康奈尔大学 用于防止和治疗急性肾损伤的方法
EP3563862B1 (de) 2009-03-20 2021-05-05 The General Hospital Corporation d/b/a Massachusetts General Hospital D-arg-2'6'-dimethyltyrosin-lys-phe-nh2 zur verhinderung von sekundären komplikationen von brandverletzungen
CA2770688C (en) * 2009-08-12 2018-06-05 Cornell University Methods for preventing or treating metabolic syndrome
SI3708178T1 (sl) 2009-08-24 2024-01-31 Stealth Biotherapeutics Inc. Peptid za uporabo pri preprečevanju ali zdravljenju degeneracije makule
EP3603658B1 (de) 2009-10-05 2025-01-08 Cornell University Peptide zur verwendung in der behandlung von herzinsuffizienz verursacht durch hypertrophe cardiomyopathy
US20160176930A1 (en) 2010-07-09 2016-06-23 The Administrators Of The Tulane Educational Fund Mu opioid receptor agonist analogs of the endomorphins
US20120083452A1 (en) 2010-09-30 2012-04-05 Perricone Nicholas V Topical Anesthetic Uses of Szeto-Schiller Peptides
CA2916492A1 (en) 2013-06-27 2014-12-31 Stealth Biotherapeutics Corp Peptide therapeutics and methods for using same
WO2015183963A2 (en) * 2014-05-28 2015-12-03 Stealth Peptides International, Inc. Therapeutic compositions including redox-active parabenzoquinones and uses thereof
WO2016011318A1 (en) * 2014-07-17 2016-01-21 Cardimetrix Llc Device for monitoring for effectiveness of heart failure therapy
US11034724B2 (en) 2017-04-05 2021-06-15 Stealth Biotherapeutics Corp. Crystalline salt forms of Boc-D-Arg-DMT-Lys-(Boc)-Phe-NH2
US10676506B2 (en) 2018-01-26 2020-06-09 Stealth Biotherapeutics Corp. Crystalline bis- and tris-hydrochloride salt of elamipretide
US11389431B2 (en) 2020-09-09 2022-07-19 Social Profit Network Methods and compositions for delivery of biotin to mitochondria

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG64368A1 (en) 1988-06-30 1999-04-27 Astra Ab Dermorphin analogs their methods of preparation pharmaceutical compositions and methods of therapeutic treatment using the same
US5602100A (en) 1988-06-30 1997-02-11 Astra Ab Dermorphin analogs having pharmacological activity
SE9503924D0 (sv) 1995-08-18 1995-11-07 Astra Ab Novel opioid peptides
IS4261A (is) * 1994-02-21 1995-08-22 Astra Aktiebolag Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra
EP0747092B1 (de) 1995-06-09 2003-12-03 Hisamitsu Pharmaceutical Co., Inc. Matrix für Iontophorese
SE9900961D0 (sv) 1999-03-16 1999-03-16 Astra Ab Novel compounds
US6900178B2 (en) * 2000-09-12 2005-05-31 University Of Kentucky Research Foundation Protection against ischemia and reperfusion injury

Also Published As

Publication number Publication date
WO2002005748A3 (en) 2002-03-28
CA2416475C (en) 2011-10-11
EP1303186A4 (de) 2007-02-07
US7732398B2 (en) 2010-06-08
US20040029796A1 (en) 2004-02-12
AU2001277908A1 (en) 2002-01-30
EP1303186A2 (de) 2003-04-23
DE60143945D1 (de) 2011-03-10
EP1303186B1 (de) 2011-01-26
US7498297B2 (en) 2009-03-03
US20070027070A1 (en) 2007-02-01
CA2416475A1 (en) 2002-01-24
WO2002005748A2 (en) 2002-01-24

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