ATE495196T1 - Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizität - Google Patents

Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizität

Info

Publication number
ATE495196T1
ATE495196T1 AT04820430T AT04820430T ATE495196T1 AT E495196 T1 ATE495196 T1 AT E495196T1 AT 04820430 T AT04820430 T AT 04820430T AT 04820430 T AT04820430 T AT 04820430T AT E495196 T1 ATE495196 T1 AT E495196T1
Authority
AT
Austria
Prior art keywords
peptide
carrier conjugate
producing
peptide carrier
high immunogenicity
Prior art date
Application number
AT04820430T
Other languages
English (en)
Inventor
Elisabetta Bianchi
Marco Finotto
Paolo Ingallinella
Antonello Pessi
Original Assignee
Angeletti P Ist Richerche Bio
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeletti P Ist Richerche Bio filed Critical Angeletti P Ist Richerche Bio
Application granted granted Critical
Publication of ATE495196T1 publication Critical patent/ATE495196T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04820430T 2003-12-18 2004-12-10 Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizität ATE495196T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53086703P 2003-12-18 2003-12-18
PCT/EP2004/014160 WO2005058968A1 (en) 2003-12-18 2004-12-10 A method to make a peptide-carrier conjugate with a high immunogenicity

Publications (1)

Publication Number Publication Date
ATE495196T1 true ATE495196T1 (de) 2011-01-15

Family

ID=34700173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04820430T ATE495196T1 (de) 2003-12-18 2004-12-10 Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizität

Country Status (5)

Country Link
US (1) US20090104220A1 (de)
EP (1) EP1704167B1 (de)
AT (1) ATE495196T1 (de)
DE (1) DE602004031051D1 (de)
WO (1) WO2005058968A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5069558B2 (ja) 2004-06-01 2012-11-07 メルク・シャープ・エンド・ドーム・コーポレイション ＨＩＶｇｐ４１融合中間物質の安定したペプチド模倣薬
WO2009111865A1 (en) * 2008-03-12 2009-09-17 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Health Reagents and methods for detecting influenza virus proteins
WO2013050048A2 (en) 2011-10-07 2013-04-11 Skau Aps Identification and attenuation of the immunosuppressive domains in fusion proteins of enveloped rna viruses
CN102964432B (zh) * 2012-11-22 2014-02-05 中国科学院微生物研究所 抑制a型流感病毒m1蛋白发生磷酸化的方法及其应用
PL2983706T3 (pl) * 2013-04-10 2021-11-02 Isd Immunotech Aps Zastosowanie domen tłumiących układ immunologiczny jako leków
WO2015168380A1 (en) * 2014-04-30 2015-11-05 Massachusetts Institute Of Technology Siderophore-based immunization against gram-negative bacteria
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98845A0 (en) * 1990-07-19 1992-07-15 Merck & Co Inc Coconjugate vaccines comprising immunogenic protein,hiv related peptides,and anionic moieties,their preparation and pharmaceutical compositions containing them
EP0519554A1 (de) * 1991-06-19 1992-12-23 Merck & Co. Inc. Konjugate des Klasse-II-Proteins der äusseren Membran von Neisseria Meningitidis mit HIV-1-verwandten Peptiden
US5274122A (en) * 1992-10-15 1993-12-28 Merck & Co., Inc. Acidic derivatives of homocysteine thiolactone
GB2271995A (en) * 1992-10-15 1994-05-04 Merck & Co Inc HIV peptide conjugated via anionic spacer to protein
GB2294047A (en) * 1994-10-14 1996-04-17 Merck & Co Inc Synthetic peptides for use as epitopes specific for HIV
JP2004509846A (ja) * 2000-06-02 2004-04-02 メルク　エンド　カムパニー　インコーポレーテッド 肝炎ｃ型ウイルスコンジュゲート

Also Published As

Publication number Publication date
DE602004031051D1 (de) 2011-02-24
EP1704167B1 (de) 2011-01-12
WO2005058968A1 (en) 2005-06-30
EP1704167A1 (de) 2006-09-27
US20090104220A1 (en) 2009-04-23

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Legal Events

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