ATE49749T1 - Aminosaeurederivate mit antitumoraktivitaet sowie diese derivate enthaltende zusammensetzungen. - Google Patents

Aminosaeurederivate mit antitumoraktivitaet sowie diese derivate enthaltende zusammensetzungen.

Info

Publication number
ATE49749T1
ATE49749T1 AT85305052T AT85305052T ATE49749T1 AT E49749 T1 ATE49749 T1 AT E49749T1 AT 85305052 T AT85305052 T AT 85305052T AT 85305052 T AT85305052 T AT 85305052T AT E49749 T1 ATE49749 T1 AT E49749T1
Authority
AT
Austria
Prior art keywords
derivatives
amino acid
antitumoric
activity
compositions containing
Prior art date
Application number
AT85305052T
Other languages
English (en)
Inventor
Takashi Matsui
Mitsuo Nagano
Koichi Kitamura
Fusaaki Shimizu
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE49749T1 publication Critical patent/ATE49749T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT85305052T 1984-07-13 1985-07-15 Aminosaeurederivate mit antitumoraktivitaet sowie diese derivate enthaltende zusammensetzungen. ATE49749T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59145731A JPH0662529B2 (ja) 1984-07-13 1984-07-13 アミノ酸誘導体
EP85305052A EP0173441B1 (de) 1984-07-13 1985-07-15 Aminosäurederivate mit Antitumoraktivität sowie diese Derivate enthaltende Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE49749T1 true ATE49749T1 (de) 1990-02-15

Family

ID=15391835

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85305052T ATE49749T1 (de) 1984-07-13 1985-07-15 Aminosaeurederivate mit antitumoraktivitaet sowie diese derivate enthaltende zusammensetzungen.

Country Status (7)

Country Link
US (1) US4904680A (de)
EP (1) EP0173441B1 (de)
JP (1) JPH0662529B2 (de)
AT (1) ATE49749T1 (de)
CA (1) CA1283917C (de)
DE (1) DE3575554D1 (de)
ES (3) ES8703830A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01250370A (ja) * 1987-12-23 1989-10-05 Zeria Pharmaceut Co Ltd 新規アミノ酸イミド誘導体、製法ならびに用途
FR2646847B1 (fr) * 1989-05-12 1991-07-12 Rhone Poulenc Sante N-phenyl amides, leurs procedes de preparation et les medicaments les contenant
JPH0524090U (ja) * 1991-09-20 1993-03-30 仲秋 張 ジグソーパズル
HU211995B (en) * 1992-06-30 1996-01-29 Gyogyszerkutato Intezet Process to prepare novel benzoyl amino acid derivs. and pharmaceutical compns. contg.them
US5854250A (en) * 1995-10-11 1998-12-29 Gyogyszerkutato Intezet Kft N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same
TR199903120T2 (xx) * 1997-05-07 2000-05-22 Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften Yeni sistein türevleri, bunların üretimi için işlemler ve bunları ihtiva eden farmasötik maddeler.
ES2302363T3 (es) * 1997-12-18 2008-07-01 Boehringer Ingelheim Pharmaceuticals Inc. Piridonas como inhibidores del dominia sh2 del grupo src.
US7427496B2 (en) * 1999-06-25 2008-09-23 The Regents Of The University Of Colorado Anti-cancer compounds
JP2003528071A (ja) 2000-03-23 2003-09-24 エラン ファーマスーティカルズ インコーポレイテッド アルツハイマー病治療用組成物および方法
JP2004502665A (ja) 2000-06-30 2004-01-29 イーラン　ファーマスーティカルズ、インコーポレイテッド アルツハイマー病を治療する化合物
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
WO2003002122A1 (en) 2001-06-27 2003-01-09 Elan Pharmaceuticals, Inc. Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
ES2360882T3 (es) * 2002-03-28 2011-06-10 Merck Serono Sa Derivados de tiazolidina carboxamida como moduladores del receptor de prostaglandina f.
DE102005028492A1 (de) * 2005-06-20 2006-12-28 Basf Ag Verfahren zur Herstellung von optisch aktiven Aminoalkylphenolen
UY37879A (es) 2017-09-13 2019-03-29 Amgen Inc Compuestos de bisamida que activan el sarcómero y sus usos
CN117945945A (zh) * 2022-10-28 2024-04-30 浙江友宁生物医药科技有限公司 一种gpr139受体激动剂、其制备方法及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE213641C (de) *
DE363467C (de) 1917-11-21 1922-11-09 Physikalisch Chemische Werke A Trockenelement, bei dem zwei verdickte Elektrolyte, von denen jeder eine Elektrode enthaelt, durch ein Kohlediaphragma voneinander getrennt sind
DE1236519B (de) * 1959-09-19 1967-03-16 Nippon Shinyaku Co Ltd Verfahren zum Herstellen eines analgetisch wirksamen Salicylsaeure-Derivates
DE1793613A1 (de) * 1966-05-13 1971-09-02 Francia Farma gamma-Orthohydroxybenzamidbutyramid
CH513123A (de) * 1967-09-25 1971-09-30 Bayer Ag Verfahren zur Herstellung von N-Acyl-a-aminosäureamiden bzw. -peptiden
IE33790B1 (en) * 1968-06-04 1974-10-30 Beecham Group Ltd Derivatives of n-acylaminoacid amides
DE2139641A1 (de) * 1971-08-07 1973-02-15 Bayer Ag 2-(p-chlorbenzoylamino)-carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
AU518147B2 (en) * 1976-12-03 1981-09-17 E.R. Squibb & Sons, Inc. Derivatives of thiazolidine, thiazine and morpholine carboxylic acids
DE3276110D1 (en) * 1981-03-04 1987-05-27 Ici Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them

Also Published As

Publication number Publication date
ES8801185A1 (es) 1988-01-01
JPH0662529B2 (ja) 1994-08-17
EP0173441B1 (de) 1990-01-24
ES8801186A1 (es) 1988-01-01
JPS6124550A (ja) 1986-02-03
CA1283917C (en) 1991-05-07
DE3575554D1 (de) 1990-03-01
EP0173441A1 (de) 1986-03-05
ES557196A0 (es) 1988-01-01
ES557197A0 (es) 1988-01-01
ES8703830A1 (es) 1987-03-01
US4904680A (en) 1990-02-27
ES545170A0 (es) 1987-03-01

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee