ES557196A0 - Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral - Google Patents

Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral

Info

Publication number
ES557196A0
ES557196A0 ES557196A ES557196A ES557196A0 ES 557196 A0 ES557196 A0 ES 557196A0 ES 557196 A ES557196 A ES 557196A ES 557196 A ES557196 A ES 557196A ES 557196 A0 ES557196 A0 ES 557196A0
Authority
ES
Spain
Prior art keywords
amino acid
acid amides
procedure
preparation
antitumoral activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES557196A
Other languages
English (en)
Other versions
ES8801185A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES8801185A1 publication Critical patent/ES8801185A1/es
Publication of ES557196A0 publication Critical patent/ES557196A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
ES557196A 1984-07-13 1986-11-13 Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral Expired ES8801185A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59145731A JPH0662529B2 (ja) 1984-07-13 1984-07-13 アミノ酸誘導体

Publications (2)

Publication Number Publication Date
ES8801185A1 ES8801185A1 (es) 1988-01-01
ES557196A0 true ES557196A0 (es) 1988-01-01

Family

ID=15391835

Family Applications (3)

Application Number Title Priority Date Filing Date
ES545170A Expired ES8703830A1 (es) 1984-07-13 1985-07-12 Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral.
ES557197A Expired ES8801186A1 (es) 1984-07-13 1986-11-13 Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral
ES557196A Expired ES8801185A1 (es) 1984-07-13 1986-11-13 Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES545170A Expired ES8703830A1 (es) 1984-07-13 1985-07-12 Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral.
ES557197A Expired ES8801186A1 (es) 1984-07-13 1986-11-13 Un procedimiento para la preparacion de amidas de aminoacido con actividad antitumoral

Country Status (7)

Country Link
US (1) US4904680A (es)
EP (1) EP0173441B1 (es)
JP (1) JPH0662529B2 (es)
AT (1) ATE49749T1 (es)
CA (1) CA1283917C (es)
DE (1) DE3575554D1 (es)
ES (3) ES8703830A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01250370A (ja) * 1987-12-23 1989-10-05 Zeria Pharmaceut Co Ltd 新規アミノ酸イミド誘導体、製法ならびに用途
FR2646847B1 (fr) * 1989-05-12 1991-07-12 Rhone Poulenc Sante N-phenyl amides, leurs procedes de preparation et les medicaments les contenant
JPH0524090U (ja) * 1991-09-20 1993-03-30 仲秋 張 ジグソーパズル
HU211995B (en) * 1992-06-30 1996-01-29 Gyogyszerkutato Intezet Process to prepare novel benzoyl amino acid derivs. and pharmaceutical compns. contg.them
US5854250A (en) * 1995-10-11 1998-12-29 Gyogyszerkutato Intezet Kft N-benzoylamino acid derivatives, pharmaceutical compositions containing them and process of preparing same
WO1998050351A1 (en) * 1997-05-07 1998-11-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., Berlin New cysteine derivatives, processes for their production, and pharmaceuticals containing them
WO1999031066A1 (en) * 1997-12-18 1999-06-24 Boehringer Ingelheim Pharmaceuticals, Inc. Pyridones as src family sh2 domain inhibitors
US7427496B2 (en) * 1999-06-25 2008-09-23 The Regents Of The University Of Colorado Anti-cancer compounds
DE60124080T2 (de) 2000-03-23 2007-03-01 Elan Pharmaceuticals, Inc., San Francisco Verbindungen und verfahren zur behandlung der alzheimerschen krankheit
JP2004502664A (ja) 2000-06-30 2004-01-29 イーラン　ファーマスーティカルズ、インコーポレイテッド アルツハイマー病処置用化合物
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
PE20020276A1 (es) 2000-06-30 2002-04-06 Elan Pharm Inc COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
BR0210721A (pt) 2001-06-27 2004-07-20 Elan Pharm Inc Composto, sal ou éster farmaceuticamente aceitável, método para fabricar um composto, e, método para tratar um paciente que tem, ou para evitar que o paciente adquira uma doença ou condição
DE60335175D1 (de) * 2002-03-28 2011-01-13 Merck Serono Sa Thiazolidin-carbonsäureamid-derivate als modulatoren des prostaglandin-f-rezeptors
DE102005028492A1 (de) * 2005-06-20 2006-12-28 Basf Ag Verfahren zur Herstellung von optisch aktiven Aminoalkylphenolen
PE20200924A1 (es) 2017-09-13 2020-09-14 Amgen Inc Compuestos de bisamida sustituida que activan el sarcomero cardiaco
CN117945945A (zh) * 2022-10-28 2024-04-30 浙江友宁生物医药科技有限公司 一种gpr139受体激动剂、其制备方法及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE213641C (es) *
DE363467C (de) 1917-11-21 1922-11-09 Physikalisch Chemische Werke A Trockenelement, bei dem zwei verdickte Elektrolyte, von denen jeder eine Elektrode enthaelt, durch ein Kohlediaphragma voneinander getrennt sind
DE1236519B (de) * 1959-09-19 1967-03-16 Nippon Shinyaku Co Ltd Verfahren zum Herstellen eines analgetisch wirksamen Salicylsaeure-Derivates
DE1793613A1 (de) * 1966-05-13 1971-09-02 Francia Farma gamma-Orthohydroxybenzamidbutyramid
CH513123A (de) * 1967-09-25 1971-09-30 Bayer Ag Verfahren zur Herstellung von N-Acyl-a-aminosäureamiden bzw. -peptiden
IE33790B1 (en) * 1968-06-04 1974-10-30 Beecham Group Ltd Derivatives of n-acylaminoacid amides
DE2139641A1 (de) * 1971-08-07 1973-02-15 Bayer Ag 2-(p-chlorbenzoylamino)-carbonsaeureamide, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
AU518147B2 (en) * 1976-12-03 1981-09-17 E.R. Squibb & Sons, Inc. Derivatives of thiazolidine, thiazine and morpholine carboxylic acids
DE3276110D1 (en) * 1981-03-04 1987-05-27 Ici Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them

Also Published As

Publication number Publication date
ATE49749T1 (de) 1990-02-15
ES8703830A1 (es) 1987-03-01
CA1283917C (en) 1991-05-07
DE3575554D1 (de) 1990-03-01
US4904680A (en) 1990-02-27
ES557197A0 (es) 1988-01-01
ES8801186A1 (es) 1988-01-01
JPS6124550A (ja) 1986-02-03
ES8801185A1 (es) 1988-01-01
JPH0662529B2 (ja) 1994-08-17
EP0173441A1 (en) 1986-03-05
EP0173441B1 (en) 1990-01-24
ES545170A0 (es) 1987-03-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519