ATE498135T1 - Homogener doppelrezeptor-agglutinationstest für immunsuppressiva - Google Patents
Homogener doppelrezeptor-agglutinationstest für immunsuppressivaInfo
- Publication number
- ATE498135T1 ATE498135T1 AT07786032T AT07786032T ATE498135T1 AT E498135 T1 ATE498135 T1 AT E498135T1 AT 07786032 T AT07786032 T AT 07786032T AT 07786032 T AT07786032 T AT 07786032T AT E498135 T1 ATE498135 T1 AT E498135T1
- Authority
- AT
- Austria
- Prior art keywords
- immunosupressives
- agglutination test
- receptor
- homogeneous
- dual receptor
- Prior art date
Links
- 230000004520 agglutination Effects 0.000 title abstract 2
- 230000009977 dual effect Effects 0.000 title 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 238000007818 agglutination assay Methods 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000002596 correlated effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 230000001861 immunosuppressant effect Effects 0.000 abstract 1
- 230000036963 noncompetitive effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80724506P | 2006-07-13 | 2006-07-13 | |
| US11/772,886 US20080081379A1 (en) | 2006-07-13 | 2007-07-03 | Homogeneous double receptor agglutination assay for immunosuppressant drugs |
| PCT/EP2007/006200 WO2008006588A1 (en) | 2006-07-13 | 2007-07-12 | Homogeneous double receptor agglutination assay for immunosuppressant drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE498135T1 true ATE498135T1 (de) | 2011-02-15 |
Family
ID=38535540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07786032T ATE498135T1 (de) | 2006-07-13 | 2007-07-12 | Homogener doppelrezeptor-agglutinationstest für immunsuppressiva |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080081379A1 (de) |
| EP (1) | EP2041580B1 (de) |
| JP (1) | JP2009543084A (de) |
| AT (1) | ATE498135T1 (de) |
| CA (1) | CA2657588A1 (de) |
| DE (1) | DE602007012439D1 (de) |
| WO (1) | WO2008006588A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5364096B2 (ja) * | 2007-08-17 | 2013-12-11 | コリア アドバンスド インスティチュート オブ サイエンス アンド テクノロジィ | 物質の相互作用検出方法 |
| SG190572A1 (en) | 2008-04-29 | 2013-06-28 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| CA2726087A1 (en) | 2008-06-03 | 2009-12-10 | Tariq Ghayur | Dual variable domain immunoglobulins and uses thereof |
| WO2010123993A1 (en) * | 2009-04-21 | 2010-10-28 | Tuan Vo-Dinh | Non-invasive energy upconversion methods and systems for in-situ photobiomodulation |
| UY33492A (es) | 2010-07-09 | 2012-01-31 | Abbott Lab | Inmunoglobulinas con dominio variable dual y usos de las mismas |
| EP3252072A3 (de) | 2010-08-03 | 2018-03-14 | AbbVie Inc. | Immunglobuline mit zweifacher variabler domäne und verwendungen davon |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| CA2815085C (en) | 2010-10-22 | 2022-06-21 | T2 Biosystems, Inc. | Nmr systems and methods for the rapid detection of analytes |
| US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| EP2839038B1 (de) | 2012-04-20 | 2019-01-16 | T2 Biosystems, Inc. | Zusammensetzungen und verfahren für den nachweis einer candida-spezies |
| CN107110853A (zh) | 2015-01-09 | 2017-08-29 | 阿通诺米斯公司 | 确定TNFα抑制药及其相应抗药抗体的量的通用测定法 |
| JP7523776B2 (ja) | 2016-01-21 | 2024-07-29 | ティー2 バイオシステムズ,インコーポレーテッド | 細菌を迅速に検出するnmr法及びシステム |
| WO2018007327A1 (en) * | 2016-07-08 | 2018-01-11 | Atonomics A/S | A universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples |
| CN110191955B (zh) | 2016-12-13 | 2024-05-31 | 西雅图儿童医院(Dba西雅图儿童研究所) | 在体外和体内对工程化的细胞中表达的化学物质诱导的信号传导复合物进行外源性药物激活的方法 |
| WO2019210057A1 (en) | 2018-04-27 | 2019-10-31 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Rapamycin resistant cells |
| US20220229049A1 (en) * | 2019-06-28 | 2022-07-21 | Siemens Healthcare Diagnostics Inc. | Reagents for sandwich immunoassays using particle enhanced agglutination detection and methods of production and use thereof |
| JP2024113375A (ja) * | 2023-02-09 | 2024-08-22 | 日本光電工業株式会社 | 試料中の測定対象物を検出する免疫測定方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH032565A (ja) * | 1989-05-30 | 1991-01-08 | Olympus Optical Co Ltd | 免疫学的分析方法 |
| DE69133095T2 (de) * | 1990-11-20 | 2003-03-27 | Dade Behring Marburg Gmbh | Cyclosporin-Immunoassay |
| GB9307491D0 (en) * | 1993-04-08 | 1993-06-02 | Sandoz Ltd | Organic compounds |
| US5874239A (en) * | 1993-07-30 | 1999-02-23 | Affymax Technologies N.V. | Biotinylation of proteins |
| US6187547B1 (en) | 1993-09-08 | 2001-02-13 | Novartis Ag | Assay kit |
| JP3292766B2 (ja) * | 1993-09-20 | 2002-06-17 | 積水化学工業株式会社 | 糖化蛋白の測定方法 |
| MX9603838A (es) | 1994-03-10 | 1997-03-29 | Fujisawa Pharmaceutical Co | Metodo para ensayar inmunosupresores. |
| US6150137A (en) * | 1994-05-27 | 2000-11-21 | Ariad Pharmaceuticals, Inc. | Immunosuppressant target proteins |
| US5922551A (en) * | 1997-03-20 | 1999-07-13 | Accumetrics, Inc. | Agglutrimetric platelet binding assays in blood |
| US6709873B1 (en) * | 1997-04-09 | 2004-03-23 | Isodiagnostika Inc. | Method for production of antibodies to specific sites of rapamycin |
| JP3513075B2 (ja) * | 2000-04-05 | 2004-03-31 | デンカ生研株式会社 | 免疫測定法及びそのための試薬 |
| EP1239285A1 (de) | 2001-03-07 | 2002-09-11 | Roche Diagnostics GmbH | Verbesserte Methode für ein homogenes Immunotestverfahren |
| US20030003503A1 (en) * | 2001-06-29 | 2003-01-02 | Tsai Tenlin S. | Enhancing sensitivity and equimolar detection through modifications of the reaction environment |
| EP1699415A4 (de) | 2003-12-29 | 2008-01-09 | Univ Ramot | Assay zum nachweis von rapamycin und rapamycin-analoga |
| WO2005088307A1 (en) | 2004-03-10 | 2005-09-22 | Seradyn Inc. | Immunoassays for everolimus |
| US8021849B2 (en) * | 2004-11-05 | 2011-09-20 | Siemens Healthcare Diagnostics Inc. | Methods and kits for the determination of sirolimus in a sample |
| EP2180323B1 (de) * | 2005-04-06 | 2012-02-01 | Abbott Laboratories | Verfahren zur Messung immunsuppressiver Tacrolimus-, Sirolimus- und Cyclosporin-A-Komplexe in einer Blutprobe |
| US7611908B2 (en) * | 2005-05-02 | 2009-11-03 | Bioscale, Inc. | Method and apparatus for therapeutic drug monitoring using an acoustic device |
| US7642059B2 (en) * | 2005-09-07 | 2010-01-05 | Roche Diagnostics Operations, Inc. | Single receptor assays for immunosuppressive drugs |
-
2007
- 2007-07-03 US US11/772,886 patent/US20080081379A1/en not_active Abandoned
- 2007-07-12 AT AT07786032T patent/ATE498135T1/de active
- 2007-07-12 JP JP2009518797A patent/JP2009543084A/ja active Pending
- 2007-07-12 CA CA002657588A patent/CA2657588A1/en not_active Abandoned
- 2007-07-12 DE DE602007012439T patent/DE602007012439D1/de active Active
- 2007-07-12 WO PCT/EP2007/006200 patent/WO2008006588A1/en not_active Ceased
- 2007-07-12 EP EP07786032A patent/EP2041580B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| DE602007012439D1 (de) | 2011-03-24 |
| CA2657588A1 (en) | 2008-01-17 |
| EP2041580A1 (de) | 2009-04-01 |
| WO2008006588A1 (en) | 2008-01-17 |
| JP2009543084A (ja) | 2009-12-03 |
| EP2041580B1 (de) | 2011-02-09 |
| US20080081379A1 (en) | 2008-04-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE498135T1 (de) | Homogener doppelrezeptor-agglutinationstest für immunsuppressiva | |
| BR112012009846A2 (pt) | ensaios para detecção de anticorpos específicos para anticorpos anti-ige terapêuticos e seu uso em anafilaxia | |
| EP2438442A4 (de) | Verfahren und tests zur messung von p95 und/oder p95 in einer probe und für p95 spezifische antikörper | |
| BRPI1007867B8 (pt) | anticorpo recombinante ou fragmento de ligação ao antígeno do mesmo, composição farmacêutica e kit compreendendo o referido anticorpo, métodos de detecção de antígeno de troponina i em uma amostra de teste e métodos in vitro de diagnóstico de síndrome coronariana aguda ou infarto do miocárdio em um paciente | |
| BRPI0915619A2 (pt) | métodos para determinar uma probabilidade de que um sujeito tenha contribuído com material genético para amostra de teste de material genético, para caracterizar amostra de teste de material genético e para determinar se uma pessoa de interesse contribuiu com material genético para uma amostra de teste de material genético, kit para análise de amostra de teste de material genético e sistema para determinar se um sujeito contribuiu com material genético para uma amostra | |
| WO2010046443A3 (en) | Methods for detection and diagnosis of a bone or cartilage disorder | |
| JP2011524537A5 (de) | ||
| WO2009079156A3 (en) | Detection devices and methods | |
| ATE485514T1 (de) | Immunoassay mit mehreren analyten | |
| BRPI0923199B8 (pt) | método para determinar a presença de anticorpos de fixação de complemento | |
| BR112012031071A2 (pt) | 8-proteínas de ligação à il-1 | |
| BRPI0720707A2 (pt) | Sistema de teste para uso com um tampão para testar a presença de moléculas alvo de um ou mais tipos de alvo em uma amostra de teste biológico; sistema de teste para testar a presença de moléculas alvo de um ou mais tipos de alvo em uma amostra de teste biológico; e método de focalização de moléculas para facilitar um teste da presença de moléculas alvo de um ou mais tipos de alvo de uma amostra de teste biológico. | |
| ATE547705T1 (de) | Kohlenhydratnachweissensor | |
| BR112016010106A2 (pt) | ensaios para igfbp7 com melhor desempenho em amostras biológicas | |
| ATE412179T1 (de) | Nachweis von arzneistoffen der methamphetamingruppe | |
| BR112012019475A8 (pt) | uso de um anticorpo monoclonal anti-cd44, anticorpo monoclonal anti-cd44, anticorpo anti-cd44 humanizado e kit para a detecção da presença de hnscc em uma amostra | |
| BR112012029769A2 (pt) | processo para a detecção eletroquímica de reações de ligação | |
| ATE514081T1 (de) | T-zellen-testverfahren | |
| TR201909273T4 (tr) | Bir pegile analit spesifik bağlanma ajanının kullanıldığı partikül bazlı immünolojik test. | |
| BRPI0818529A2 (pt) | uso do ensaio sorológico da citocina estimuladora de linfócito b (blys) para um teste prognóstico e de monitoramento de reações à transfusões imune-relacionadas | |
| JP2010526995A5 (de) | ||
| WO2013169931A3 (en) | Assays and cell-based tests using a receptor na/k-atpase/src complex and uses thereof | |
| JP2009507234A5 (de) | ||
| EP2444812A3 (de) | Verbesserte Immunoassayverfahren | |
| TR201820490T4 (tr) | Çözünür fibroblast büyüme faktörü reseptörleri için hassas multipleks immunoeseyleri. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 2041580 Country of ref document: EP |