ATE499366T1 - 1-ä(6-substituiertes alkoxychinoxalinyl) - Google Patents

1-ä(6-substituiertes alkoxychinoxalinyl)

Info

Publication number: ATE499366T1
Authority: AT; Austria
Prior art keywords: substituted; alkoxychinoxalinyl; compounds; piperazine compounds; quioxaline
Prior art date: 2004-11-17

Application number

AT05809031T

Other languages

English (en)

Inventor

Young-Dae Gong

Moon-Kook Jeon

Dong-Su Kim

Jae Yang Kong

Gun-Do Kim

Chang-Ho Ahn

Young Bok Lee

Original Assignee

Rexahn Pharmaceuticals Inc

Korea Res Inst Chem Tech

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-11-17

Filing date

2005-10-18

Publication date

2011-03-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36407350&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE499366(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-11-17 Priority claimed from KR1020040094233A external-priority patent/KR100739233B1/ko

2004-11-17 Priority claimed from KR1020040094232A external-priority patent/KR20060053788A/ko

2005-10-18 Application filed by Rexahn Pharmaceuticals Inc, Korea Res Inst Chem Tech filed Critical Rexahn Pharmaceuticals Inc

2011-03-15 Application granted granted Critical

2011-03-15 Publication of ATE499366T1 publication Critical patent/ATE499366T1/de

Links

206010028980 Neoplasm Diseases 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000003463 hyperproliferative effect Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT05809031T 2004-11-17 2005-10-18 1-ä(6-substituiertes alkoxychinoxalinyl) ATE499366T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
KR1020040094233A KR100739233B1 (ko)	2004-11-17	2004-11-17	1-[(3-알콕시-6-치환-퀴녹살린-2-일)아미노카르보닐]-4-(헤테로)아릴피페라진 유도체
KR1020040094232A KR20060053788A (ko)	2004-11-17	2004-11-17	1-[(2-알콕시-6-치환-퀴녹살린-3-일)아미노카르보닐]-4-(헤테로)아릴피페라진 유도체
PCT/KR2005/003463 WO2006054830A1 (en)	2004-11-17	2005-10-18	1-[(6,7-substituted alkoxyquinoxalinyl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives

Publications (1)

Publication Number	Publication Date
ATE499366T1 true ATE499366T1 (de)	2011-03-15

Family

ID=36407350

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05809031T ATE499366T1 (de)	2004-11-17	2005-10-18	1-ä(6-substituiertes alkoxychinoxalinyl)

Country Status (12)

Country	Link
US (2)	US8314100B2 (de)
EP (1)	EP1819698B1 (de)
JP (1)	JP6097946B2 (de)
CN (1)	CN103524436B (de)
AT (1)	ATE499366T1 (de)
AU (1)	AU2005307209B2 (de)
BR (1)	BRPI0517734A (de)
CA (1)	CA2587891C (de)
DE (1)	DE602005026557D1 (de)
MX (1)	MX2007005863A (de)
PL (1)	PL1819698T3 (de)
WO (1)	WO2006054830A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX2007005863A (es)	2004-11-17	2007-10-19	Rexahn Pharmaceuticals Inc	Derivados de 1-[(6,7-alcoxiquinoxalinil 6,7-sustituido) aminocarbonil]-4-(hetero)arilpiperazina.
KR101140133B1 (ko)	2010-02-17	2012-05-02	한국화학연구원	1-(6,7-다이플루오르-3-메톡시퀴녹살린-2-일)-3-［1-(헤테로아릴메틸)피페리딘-4-일］ 우레아 유도체, 그 제조방법 및 그의 용도
JP6063090B2 (ja) *	2013-06-28	2017-01-18	レクサンファーマシューティカルズインコーポレイテッド	ナノ粒子状組成物およびピペラジン化合物の製剤
PL3231800T3 (pl) *	2014-12-08	2020-04-30	Lsk Nrdo Co., Ltd.	Nowa pochodna 4-(arylo) -n-(2-alkoksytieno[3,2-b]pirazyn-3-ylo)-piperazyno-1-karboksyamidu oraz jej działanie antyproliferacyjne
WO2017040980A2 (en)	2015-09-04	2017-03-09	Rexahn Pharmaceuticals, Inc.	Quinoxalinyl-piperazinamide methods of use
KR101872645B1 (ko) *	2016-06-09	2018-08-03	동국대학교 산학협력단	신규한 4-(아릴)-N-(3-알콕시퓨로[2,3-b]피라진-2-일)-피페라진-1-카복스아미드 유도체 및 이의 항증식 효과
WO2017213452A1 (ko) *	2016-06-09	2017-12-14	동국대학교 산학협력단	신규한 4-(아릴)-n-(3-알콕시퓨로[2,3-b]피라진-2-일)-피페라진-1-카복스아미드 유도체 및 이의 항증식 효과

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2448541A1 (fr)	1979-02-09	1980-09-05	Roussel Uclaf	Nouveaux derives de l'oxoimidazoquinoxaline et leurs sels, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
SE441449B (sv) *	1979-02-09	1985-10-07	Roussel Uclaf	Heterocykliska derivat och farmaceutiska kompositioner innehallande dessa derivat
US6028184A (en) *	1996-12-31	2000-02-22	Max-Plank-Gesellschaft Zur Forderung Der Wissenschaften E.V.	Pax6 and Pax4 nucleic acid mixtures
SK27598A3 (en)	1996-06-29	1998-11-04	Samjin Pharm Co Ltd	Piperazine derivatives and process for the preparation thereof
EP1424072A1 (de) *	1999-03-03	2004-06-02	Samjin Pharmaceutical Co., Ltd.	N'-(Pyridin-3-yl)-(4-Phenylpiperazin-1-yl)-Carboxyimidamid und -Iminothiolat Derivate zur Behandlung vom Tumoren
WO2001095856A2 (en) *	2000-06-15	2001-12-20	Chaconne Nsi Co., Ltd.	Urea derivative useful as an anti-cancer agent and process for preparing same
AR043059A1 (es) *	2002-11-12	2005-07-13	Bayer Pharmaceuticals Corp	Derivados de indolil pirazinona utiles para el tratamiento de trastornos hiper-proliferativos
KR20060003351A (ko)	2003-04-16	2006-01-10	아스트라제네카 아베	화합물
MX2007005863A (es)	2004-11-17	2007-10-19	Rexahn Pharmaceuticals Inc	Derivados de 1-[(6,7-alcoxiquinoxalinil 6,7-sustituido) aminocarbonil]-4-(hetero)arilpiperazina.

2005
- 2005-10-18 MX MX2007005863A patent/MX2007005863A/es active IP Right Grant
- 2005-10-18 WO PCT/KR2005/003463 patent/WO2006054830A1/en not_active Ceased
- 2005-10-18 AU AU2005307209A patent/AU2005307209B2/en not_active Ceased
- 2005-10-18 PL PL05809031T patent/PL1819698T3/pl unknown
- 2005-10-18 US US11/667,923 patent/US8314100B2/en not_active Expired - Fee Related
- 2005-10-18 CN CN201310540633.7A patent/CN103524436B/zh not_active Expired - Fee Related
- 2005-10-18 DE DE602005026557T patent/DE602005026557D1/de not_active Expired - Lifetime
- 2005-10-18 EP EP05809031A patent/EP1819698B1/de not_active Expired - Lifetime
- 2005-10-18 AT AT05809031T patent/ATE499366T1/de active
- 2005-10-18 JP JP2007542886A patent/JP6097946B2/ja not_active Expired - Fee Related
- 2005-10-18 BR BRPI0517734-0A patent/BRPI0517734A/pt not_active Application Discontinuation
- 2005-10-18 CA CA2587891A patent/CA2587891C/en not_active Expired - Fee Related
2012
- 2012-10-26 US US13/661,975 patent/US8598173B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2587891C (en)	2010-08-31
US8598173B2 (en)	2013-12-03
JP6097946B2 (ja)	2017-03-22
US8314100B2 (en)	2012-11-20
BRPI0517734A (pt)	2008-10-21
AU2005307209B2 (en)	2009-11-19
CA2587891A1 (en)	2006-05-26
EP1819698B1 (de)	2011-02-23
WO2006054830A1 (en)	2006-05-26
AU2005307209A1 (en)	2006-05-26
CN103524436A (zh)	2014-01-22
US20080318963A1 (en)	2008-12-25
JP2008520653A (ja)	2008-06-19
US20130053390A1 (en)	2013-02-28
MX2007005863A (es)	2007-10-19
CN103524436B (zh)	2015-09-23
DE602005026557D1 (de)	2011-04-07
PL1819698T3 (pl)	2011-08-31
EP1819698A1 (de)	2007-08-22

Legal Events

Date

Code

Title

Description

2011-07-15

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