ATE500344T1 - Einfach-primernukleinsäuren-erweiterungsverfahr n - Google Patents

Einfach-primernukleinsäuren-erweiterungsverfahr n

Info

Publication number
ATE500344T1
ATE500344T1 AT08005147T AT08005147T ATE500344T1 AT E500344 T1 ATE500344 T1 AT E500344T1 AT 08005147 T AT08005147 T AT 08005147T AT 08005147 T AT08005147 T AT 08005147T AT E500344 T1 ATE500344 T1 AT E500344T1
Authority
AT
Austria
Prior art keywords
primer extension
target sequence
extension product
dna primer
oligonucleotide
Prior art date
Application number
AT08005147T
Other languages
English (en)
Inventor
Michael M Becker
Wai-Chung Lam
Kristin W Livezey
Steven T Brentano
Daniel P Kolk
Astrid R W Schroder
Original Assignee
Gen Probe Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Probe Inc filed Critical Gen Probe Inc
Application granted granted Critical
Publication of ATE500344T1 publication Critical patent/ATE500344T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6865—Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Manufacture Of Electron Tubes, Discharge Lamp Vessels, Lead-In Wires, And The Like (AREA)
AT08005147T 2004-08-27 2005-08-26 Einfach-primernukleinsäuren-erweiterungsverfahr n ATE500344T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60483004P 2004-08-27 2004-08-27
US63911004P 2004-12-23 2004-12-23

Publications (1)

Publication Number Publication Date
ATE500344T1 true ATE500344T1 (de) 2011-03-15

Family

ID=36000589

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08005147T ATE500344T1 (de) 2004-08-27 2005-08-26 Einfach-primernukleinsäuren-erweiterungsverfahr n

Country Status (8)

Country Link
US (3) US7374885B2 (de)
EP (4) EP1970454B1 (de)
JP (1) JP4861324B2 (de)
AT (1) ATE500344T1 (de)
AU (1) AU2005280162B2 (de)
CA (4) CA2577122C (de)
DE (1) DE602005026730D1 (de)
WO (1) WO2006026388A2 (de)

Families Citing this family (167)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7311794B2 (en) 2004-05-28 2007-12-25 Wafergen, Inc. Methods of sealing micro wells
US7713697B2 (en) * 2004-08-27 2010-05-11 Gen-Probe Incorporated Methods and kits for amplifying DNA
US7374885B2 (en) * 2004-08-27 2008-05-20 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
WO2006099255A2 (en) 2005-03-10 2006-09-21 Gen-Probe Incorporated Systems and methods to perform assays for detecting or quantifying analytes within samples
EP2348320B1 (de) 2005-03-10 2024-05-01 Gen-Probe Incorporated Verfahren und Systeme zur Erkennung mehrerer Fluoreszenzemissionssignale
AU2006254891B2 (en) 2005-06-06 2011-04-14 Gen-Probe Incorporated Compositions, methods and kits for determining the presence of Chlamydophila pneumoniae in a test sample
ATE550441T1 (de) * 2005-09-06 2012-04-15 Gen Probe Inc Verfahren, zusammensetzungen und kits zur isothermischen amplifikation von nukleinsäuren
US9957569B2 (en) * 2005-09-12 2018-05-01 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
US7718369B2 (en) * 2005-09-12 2010-05-18 The Regents Of The University Of Michigan Recurrent gene fusions in prostate cancer
EP2400037A1 (de) 2005-10-17 2011-12-28 Gen-Probe Incorporated Zusammensetzungen und Verfahren zum Nachweisen von Legionella-pneumophila-Nukleinsäure
WO2007120843A2 (en) * 2006-04-12 2007-10-25 Siemens Healthcare Diagnostics Inc. Single nucleotide polymorphism detection from unamplified genomic dna
US20070243534A1 (en) * 2006-04-12 2007-10-18 Michael Seul Probe density considerations and elongation of self-complementary looped probes where probes are attached to a solid phase
CA2651946A1 (en) * 2006-05-12 2007-11-22 Gen-Probe Incorporated Compositions and methods to detect enterococci nucleic acid
PL2017356T3 (pl) * 2006-06-06 2012-03-30 Gen Probe Inc Znakowane oligonukleotydy i ich zastosowanie w sposobach amplifikacji kwasu nukleinowego
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
US7501254B2 (en) 2006-07-20 2009-03-10 Ghc Technologies, Inc. Methods and compositions for amplification and capture of nucleic acid sequences
EP1921156A1 (de) * 2006-11-10 2008-05-14 bioMerieux B.V. Verbesserte multiplexe Nukleinsäureamplifikation mittels blockierter Primer
US8198027B2 (en) 2006-12-21 2012-06-12 Gen-Probe Incorporated Methods and compositions for nucleic acid amplification
CN101605911A (zh) * 2007-01-17 2009-12-16 梅里第安生物科学公司 有效用于核酸的环-介导的等温扩增(lamp)的稳定试剂和试剂盒
US8183359B2 (en) 2007-03-01 2012-05-22 Gen-Probe Incorporated Kits for amplifying DNA
CA2678799A1 (en) * 2007-03-01 2008-09-12 Gen-Probe Incorporated Methods and kits for amplifying dna
EP1978111B1 (de) 2007-04-02 2013-03-27 Gen-Probe Incorporated Zusammensetzungen, Kits und zugehörige Verfahren zur Erkennung und/oder Überwachung von Pseudomonas aeruginosa
CA2691197C (en) 2007-06-21 2013-03-12 Gen-Probe Incorporated Instrument and receptacles for use in performing processes
WO2009009431A2 (en) 2007-07-06 2009-01-15 The Regents Of The University Of Michigan Mipol1-etv1 gene rearrangements
EP2167689B1 (de) 2007-07-06 2012-10-31 The Regents Of The University Of Michigan Wiederkehrende genfusionen bei prostatakrebs
AU2008275978B9 (en) * 2007-07-18 2014-11-20 Gen-Probe Incorporated Compositions and methods to detect TMPRSS2/ERG transcript variants in prostate cancer
CA2709519A1 (en) 2007-12-21 2009-07-09 Gen-Probe Incorporated Detection of antibiotic-resistant microorganisms
EP2235214B1 (de) * 2007-12-26 2014-07-09 Gen Probe Inc Zusammensetzungen und verfahren für den nachweis von candida albicans-nukleinsäure
US20090269764A1 (en) * 2008-02-19 2009-10-29 Gen-Probe Incorporated Compositions and methods for detection of propionibacterium acnes nucleic acid
CA2719247C (en) * 2008-03-25 2017-03-21 The Regents Of The University Of Michigan Ikki inhibitor therapies and screening methods, and related ikki diagnostics
EP2806037B1 (de) 2008-05-13 2016-09-21 Gen-Probe Incorporated Inaktivierbare Target-Capture-Oligomere zur Verwendung bei der selektiven Hybridisierung und beim Fangen von Zielnukleinsäuresequenzen
EP2806054A1 (de) 2008-05-28 2014-11-26 Genomedx Biosciences Inc. Systeme und Verfahren zur expressionsbasierten Unterscheidung verschiedener klinischer Krankheitszustände bei Prostatakrebs
WO2009158119A2 (en) * 2008-05-30 2009-12-30 Gen-Probe Incorporated Compositions, kits and related methods for the detection and/or monitoring of salmonella
WO2010030461A2 (en) * 2008-09-12 2010-03-18 Promega Corporation Assessing expression of endogenous and exogenous genes
US8258283B2 (en) * 2008-12-29 2012-09-04 Lg Life Sciences Ltd. Method for detection of HCV at the real time PCR with intercalating dye
JP5793085B2 (ja) 2008-12-30 2015-10-14 ジェン−プローブ・インコーポレーテッド Ｌｉｓｔｅｒｉａを検出およびモニターするための組成物、キットおよび関連する方法
JP2012514475A (ja) 2009-01-09 2012-06-28 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 癌における再現性の遺伝子融合物
EP2391452B1 (de) 2009-01-30 2015-06-17 Gen-Probe Incorporated Systeme und verfahren zur erfassung eines signals und beaufschlagung des signalübertragungselements mit wärmeenergie
WO2010114842A1 (en) 2009-03-30 2010-10-07 Ibis Biosciences, Inc. Bioagent detection systems, devices, and methods
WO2010126913A1 (en) 2009-04-27 2010-11-04 Gen-Probe Incorporated Methods and kits for use in the selective amplification of target sequences
CA2768768C (en) 2009-06-23 2021-08-24 Gen-Probe Incorporated Compositions and methods for detecting nucleic acid from mollicutes
EP2449132B1 (de) 2009-07-01 2015-05-13 Gen-Probe Incorporated Verfahren und zusammensetzungen zur erweiterung von nukleinsäuren
US8628924B2 (en) 2009-07-21 2014-01-14 Gen-Probe Incorporated Methods and compositions for quantitative amplification and detection over a wide dynamic range
US8999675B2 (en) 2009-08-31 2015-04-07 Gen-Probe Incorporated Dengue virus assay
JP5800817B2 (ja) 2009-09-17 2015-10-28 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン 前立腺癌における再発性遺伝子融合
JP2011118905A (ja) 2009-12-07 2011-06-16 Samsung Electronics Co Ltd メモリカード及び電子機器
WO2011091393A1 (en) 2010-01-25 2011-07-28 Rd Biosciences, Inc. Self-folding amplification of target nucleic acid
WO2011103274A1 (en) 2010-02-17 2011-08-25 Gen-Probe Incorporated Compositions and methods to detect atopobium vaginae nucleic acid
EP3037555B1 (de) 2010-04-21 2019-07-24 Gen-Probe Incorporated Zusammensetzungen, verfahren und kits für den nachweis von herpes-simplex-virusnukleinsäuren
CN102985566B (zh) 2010-06-30 2015-06-17 简.探针公司 使用分析物和过程控制信号的单次读取确定而鉴定含分析物的样品的方法和设备
EP3306321A1 (de) 2010-07-07 2018-04-11 The Regents of The University of Michigan Diagnose und behandlung von brustkrebs
EP2611932A2 (de) 2010-08-30 2013-07-10 Gen-Probe Incorporated Zusammensetzungen, verfahren und reaktionsmischungen für den nachweis von xenotropic murine leukemia virus-related virus (xmrv)
CA2811333C (en) 2010-09-16 2020-05-12 Gen-Probe Incorporated Capture probes immobilizable via l-nucleotide tail
EP2625297B1 (de) 2010-10-04 2018-10-10 Gen-Probe Prodesse, Inc. Zusammensetzungen, verfahren und kits für den nachweis von adenovirus-nukleinsäuren
US20150225792A1 (en) 2014-01-17 2015-08-13 Northwestern University Compositions and methods for identifying depressive disorders
US10233501B2 (en) 2010-10-19 2019-03-19 Northwestern University Biomarkers predictive of predisposition to depression and response to treatment
US10093981B2 (en) 2010-10-19 2018-10-09 Northwestern University Compositions and methods for identifying depressive disorders
US20150218639A1 (en) 2014-01-17 2015-08-06 Northwestern University Biomarkers predictive of predisposition to depression and response to treatment
CN103403181B (zh) 2010-11-19 2016-09-07 密执安大学评议会 ncRNA及其用途
US20130267443A1 (en) 2010-11-19 2013-10-10 The Regents Of The University Of Michigan ncRNA AND USES THEREOF
US8945556B2 (en) 2010-11-19 2015-02-03 The Regents Of The University Of Michigan RAF gene fusions
EP2675275B1 (de) 2011-02-14 2017-12-20 The Regents Of The University Of Michigan Zusammensetzungen und verfahren zur behandlung von adipositas und damit zusammenhängenden erkrankungen
CN103403533B (zh) 2011-02-24 2017-02-15 简.探针公司 用于分辨光信号检测器中不同调制频率的光信号的系统和方法
WO2012122571A1 (en) 2011-03-10 2012-09-13 Gen-Probe Incorporated Methods and compositions for the selection and optimization of oligonucleotide tag sequences
US9657352B2 (en) 2011-04-25 2017-05-23 Gen-Probe Incorporated Compositions and methods for detecting BV-associated bacterial nucleic acid
US9512493B2 (en) * 2011-08-24 2016-12-06 Grifols Therapeutics Inc. Compositions, methods, and kits for nucleic acid hybridization
EP2753712B1 (de) * 2011-09-06 2017-03-22 Gen-Probe Incorporated Geschlossene nukleinsäurestrukturen
WO2013036668A1 (en) 2011-09-06 2013-03-14 Gen-Probe Incorporated Circularized templates for sequencing
WO2013036928A1 (en) * 2011-09-08 2013-03-14 Gen-Probe Incorporated Compositions and methods for detecting bv-associated bacterial nucleic acid
WO2013044097A1 (en) 2011-09-21 2013-03-28 Gen-Probe Incorporated Methods for amplifying nucleic acid using tag-mediated displacement
EP2773772A1 (de) 2011-11-04 2014-09-10 Oslo Universitetssykehus HF Verfahren und biomarker zur analyse von kolorektalkarzinomen
EP3848474A1 (de) 2011-11-04 2021-07-14 Gen-Probe Incorporated Molekulartestreagenzien und -verfahren
DE102011120550B4 (de) 2011-12-05 2013-11-07 Gen-Probe Prodesse, Inc. Zusammensetzungen, Verfahren und Kits zur Detektion von Adenovirusnukleinsäuren
WO2013096460A1 (en) 2011-12-20 2013-06-27 The Regents Of The University Of Michigan Pseudogenes and uses thereof
WO2013096838A2 (en) 2011-12-22 2013-06-27 Ibis Biosciences, Inc. Systems and methods for isolating nucleic acids
WO2013096799A1 (en) 2011-12-22 2013-06-27 Ibis Biosciences, Inc. Systems and methods for isolating nucleic acids from cellular samples
US9970061B2 (en) 2011-12-27 2018-05-15 Ibis Biosciences, Inc. Bioagent detection oligonucleotides
WO2013104990A1 (en) 2012-01-09 2013-07-18 Oslo Universitetssykehus Hf Methods and biomarkers for analysis of colorectal cancer
EP3511426B1 (de) 2012-02-01 2022-08-17 Gen-Probe Incorporated Asymmetrische hairpin-target-capture-oligomere
WO2013124738A2 (en) 2012-02-21 2013-08-29 Oslo Universitetssykehus Hf Methods and biomarkers for detection and prognosis of cervical cancer
CA3138799C (en) 2012-02-24 2024-01-02 Gen-Probe Prodesse, Inc. Detection of shiga toxin genes in bacteria
US20150111758A1 (en) 2012-03-06 2015-04-23 Oslo Universitetssykehus Hf Gene signatures associated with efficacy of postmastectomy radiotherapy in breast cancer
WO2013152114A1 (en) 2012-04-03 2013-10-10 The Regents Of The University Of Michigan Biomarker associated with irritable bowel syndrome and crohn's disease
AU2013205110B2 (en) 2012-04-24 2016-10-13 Gen-Probe Incorporated Compositions, Methods and Kits to Detect Herpes Simplex Virus Nucleic Acids
AU2013205064B2 (en) 2012-06-04 2015-07-30 Gen-Probe Incorporated Compositions and Methods for Amplifying and Characterizing HCV Nucleic Acid
AU2013202804A1 (en) 2012-06-14 2014-01-16 Gen-Probe Incorporated Use of a fluorescent material to detect failure or deteriorated performance of a fluorometer
WO2014005076A2 (en) 2012-06-29 2014-01-03 The Regents Of The University Of Michigan Methods and biomarkers for detection of kidney disorders
AU2013205087B2 (en) 2012-07-13 2016-03-03 Gen-Probe Incorporated Method for detecting a minority genotype
AU2013202793B2 (en) 2012-07-31 2014-09-18 Gen-Probe Incorporated System, method and apparatus for automated incubation
AU2013202808B2 (en) 2012-07-31 2014-11-13 Gen-Probe Incorporated System and method for performing multiplex thermal melt analysis
ES2945036T3 (es) 2012-08-16 2023-06-28 Veracyte Sd Inc Pronóstico del cáncer de próstata mediante biomarcadores
US9139870B2 (en) 2012-08-30 2015-09-22 Gen-Probe Incorporated Multiphase nucleic acid amplification
AU2013205122B2 (en) 2012-10-11 2016-11-10 Gen-Probe Incorporated Compositions and Methods for Detecting Human Papillomavirus Nucleic Acid
US20160046997A1 (en) 2012-10-18 2016-02-18 Oslo Universitetssykehus Hf Biomarkers for cervical cancer
AU2013205090B2 (en) 2012-12-07 2016-07-28 Gen-Probe Incorporated Compositions and Methods for Detecting Gastrointestinal Pathogen Nucleic Acid
US10077475B2 (en) 2013-01-24 2018-09-18 California Institute Of Technology FRET-based analytes detection and related methods and systems
EP4570924A3 (de) 2013-01-24 2025-09-03 California Institute of Technology Chromophorbasierte charakterisierungs- und nachweisverfahren
CN105378108A (zh) 2013-03-13 2016-03-02 雅培分子公司 用于分离核酸的系统和方法
EP2971175B1 (de) 2013-03-14 2019-04-17 Abbott Molecular Inc. Fehlerminimierung mittels uracil-dna-n-glycosylase
CN105209639B (zh) 2013-03-14 2020-04-17 莱尔·J·阿诺德 在固相载体扩增核酸的方法
EP2971171A4 (de) 2013-03-14 2016-11-02 Abbott Molecular Inc Multiplex-methylierungs-spezifische verstärkersysteme und -verfahren
CA2905410A1 (en) 2013-03-15 2014-09-25 Abbott Molecular Inc. Systems and methods for detection of genomic copy number changes
ES2716094T3 (es) 2013-03-15 2019-06-10 Ibis Biosciences Inc Métodos para analizar la contaminación en la secuenciación del ADN
JP2016517687A (ja) 2013-03-27 2016-06-20 サンプル テクノロジーズ，インコーポレイティド 組換えファージ及び細菌検出方法
EP2992331A4 (de) 2013-04-30 2017-03-29 Université de Montréal Neuartige biomarker für akute myeloische leukämie
US8946424B2 (en) 2013-05-02 2015-02-03 The Regents Of The University Of Michigan Deuterated amlexanox
CA2915820A1 (en) 2013-06-19 2014-12-24 Michael Sandor Koeris Phage-based bacterial detection assay
CA2920672C (en) 2013-08-14 2022-12-13 Gen-Probe Incorporated Compositions and methods for detecting hev nucleic acid
US9909181B2 (en) 2013-12-13 2018-03-06 Northwestern University Biomarkers for post-traumatic stress states
WO2015188178A1 (en) 2014-06-06 2015-12-10 The Regents Of The University Of Michigan Compositions and methods for characterizing and diagnosing periodontal disease
EP3218482A4 (de) 2014-11-11 2018-05-09 Abbott Molecular Inc. Hybridisierungssonden und verfahren
EP3242956B1 (de) 2015-01-09 2020-06-17 Gen-Probe Incorporated Verfahren und zusammensetzungen zur diagnose von bakterieller vaginose
US10208339B2 (en) 2015-02-19 2019-02-19 Takara Bio Usa, Inc. Systems and methods for whole genome amplification
DK3259602T3 (da) 2015-02-20 2021-02-15 Takara Bio Usa Inc Fremgangsmåde til hurtig nøjagtig dispensering, visualisering og analyse af enkeltceller
AU2016233298B2 (en) 2015-03-16 2021-09-02 Gen-Probe Incorporated Methods and compositions for detecting bacterial nucleic acid and diagnosing bacterial vaginosis
PL3311158T3 (pl) 2015-06-19 2023-11-27 Sera Prognostics, Inc. Pary biomarkerów do przewidywania przedwczesnego porodu
CA3008891C (en) 2015-12-31 2024-02-20 Gen-Probe Incorporated Systems and methods for analyzing a sample and for monitoring the performance of an optical signal detector
EP4249610A3 (de) 2016-01-04 2023-12-20 Gen-Probe Incorporated Verfahren und zusammensetzungen zum nachweis von candida-spezies
EP3407974A4 (de) 2016-01-29 2019-08-28 The Regents Of The University Of Michigan Amlexanox-analoga
EP3469103B1 (de) 2016-06-10 2021-10-06 Gen-Probe Incorporated Zusammensetzungen und verfahren für den nachweis von zikavirus-nukleinsäure
WO2018013509A1 (en) 2016-07-11 2018-01-18 Arizona Board Of Regents On Behalf Of The University Of Arizona Compositions and methods for diagnosing and treating arrhythmias
CA3020629A1 (en) 2016-07-21 2018-01-25 Takara Bio Usa, Inc. Multi-z imaging and dispensing with multi-well devices
AU2017315425B2 (en) 2016-08-24 2023-11-09 The Regents Of The University Of Michigan Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy
CN110736695A (zh) 2016-09-30 2020-01-31 多伦多大学管理委员会 用于鉴定和靶向异质群体中的个体细胞以选择性提取细胞内容物的系统
JP7167013B2 (ja) 2016-10-19 2022-11-08 ジェン－プローブ・インコーポレーテッド Ｃ型肝炎ウイルスを検出または定量するための組成物および方法
US10508313B2 (en) 2016-11-21 2019-12-17 Gen-Probe Incorporated Compositions and methods for detecting or quantifying Hepatitis B virus
WO2018127786A1 (en) 2017-01-06 2018-07-12 Oslo Universitetssykehus Hf Compositions and methods for determining a treatment course of action
EP3571322B9 (de) 2017-01-20 2023-10-04 VERACYTE SD, Inc. Molekulare untertypisierung, prognose und behandlung von blasenkrebs
CA3055925A1 (en) 2017-03-09 2018-09-13 Decipher Biosciences, Inc. Subtyping prostate cancer to predict response to hormone therapy
US11078542B2 (en) 2017-05-12 2021-08-03 Decipher Biosciences, Inc. Genetic signatures to predict prostate cancer metastasis and identify tumor aggressiveness
WO2018226798A1 (en) 2017-06-07 2018-12-13 Gen-Probe Incorporated Detecting babesia species nucleic acid in a sample
US12497660B2 (en) 2017-08-04 2025-12-16 Veracyte SD, Inc. Use of immune cell-specific gene expression for prognosis of prostate cancer and prediction of responsiveness to radiation therapy
EP3668996A4 (de) 2017-08-18 2021-04-21 Sera Prognostics, Inc. Clock-schwangerschaftsprotein zur vorhersage des entbindungstermins und der zeit bis zur entbindung
CN111601899A (zh) * 2017-11-13 2020-08-28 株式会社理光 孔中具有特定细胞和核酸数量的装置以及使用该装置的测试/校准方法
WO2019099629A1 (en) 2017-11-17 2019-05-23 Gen-Probe Incorporated COMPOSITIONS AND METHODS FOR DETECTING C1orf43 NUCLEIC ACID
EP3486330A1 (de) 2017-11-21 2019-05-22 Ricoh Company, Ltd. Vorrichtung
JP6447765B1 (ja) * 2017-11-21 2019-01-09 株式会社リコー 検査デバイス及びデバイス
JP6454434B1 (ja) * 2017-11-24 2019-01-16 株式会社リコー 検査装置の性能評価用検査デバイス、検査装置の性能評価プログラム、検査装置の性能評価方法、及び検査装置の性能評価装置
JP7259279B2 (ja) * 2017-11-24 2023-04-18 株式会社リコー デバイス、検査装置の性能評価プログラム、検査装置の性能評価方法、及び検査装置の性能評価装置
EP4461817A3 (de) 2018-02-06 2025-01-22 Gen-Probe Incorporated Dunkelrote farbstoffsondenformulierungen
GB2597566B (en) 2018-06-13 2023-02-01 Gen Probe Inc Compositions and methods for detecting group B streptococcus nucleic acid
EP3830302B1 (de) 2018-08-01 2022-10-05 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von nukleinsäuren des epstein-barr-virus
JP7579779B2 (ja) 2018-08-21 2024-11-08 ジェン－プローブ・インコーポレーテッド ヒトサイトメガロウイルスを増幅、検出、または定量化するための組成物および方法
KR102868953B1 (ko) 2018-08-24 2025-10-13 젠-프로브 인코포레이티드 세균성 핵산을 검출하고 세균성 질염을 진단하기 위한 조성물 및 방법
EP3856934A2 (de) 2018-09-27 2021-08-04 Gen-Probe Incorporated Zusammensetzungen und verfahren zur detektion von bordetella-pertussis- und bordetella-parapertussis-nukleinsäure
EP3861141B1 (de) 2018-10-01 2026-03-11 Gen-Probe Incorporated Zusammensetzungen und verfahren zur amplifikation oder zum nachweis von varicella-zoster-virus
JP7477095B2 (ja) * 2018-12-18 2024-05-01 株式会社リコー デバイス、核酸の検査方法及び核酸の検査装置、並びに遺伝子検査方法
WO2020129874A1 (en) * 2018-12-18 2020-06-25 Ricoh Company, Ltd. Device, nucleic acid testing method and nucleic acid testing device, and gene testing method
TW202030333A (zh) 2018-12-20 2020-08-16 美商簡 探針公司 用於檢測瘧原蟲物種核酸之組成物及方法
US20220307093A1 (en) 2019-07-03 2022-09-29 Gen-Probe Incorporated Oligonucleotides for use in determining the presence of trichomonas vaginalis in a sample
US20220333162A1 (en) * 2019-09-05 2022-10-20 Gen-Probe Incorporated Detection of chlamydia trachomatis nucleic acid variants
AU2020402029B2 (en) 2019-12-09 2022-12-15 Gen-Probe Incorporated Quantification of polynucleotide analytes from dried samples
EP4582563A3 (de) 2020-03-04 2025-10-08 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von sars-cov-2-nukleinsäure
EP4146821A1 (de) 2020-05-07 2023-03-15 Grifols Diagnostic Solutions Inc. Verfahren und zusammensetzungen zum nachweis von sars-cov-2-nukleinsäure
WO2021252574A1 (en) 2020-06-10 2021-12-16 Sera Prognostics, Inc. Nucleic acid biomarkers for placental dysfunction
CA3218222A1 (en) 2021-05-14 2022-11-17 Gen-Probe Incorporated Compositions and methods for detecting human adenovirus nucleic acid
WO2023021330A1 (en) 2021-08-16 2023-02-23 University Of Oslo Compositions and methods for determining a treatment course of action
WO2023175434A1 (en) 2022-03-15 2023-09-21 Diagenode S.A. Detection of methylation status of a dna sample
EP4282980A1 (de) 2022-05-23 2023-11-29 Mobidiag Oy Methoden zum verstärken einer nukleinsäure
EP4638804A2 (de) 2022-12-19 2025-10-29 Gen-Probe Incorporated Zusammensetzungen und verfahren zum nachweis von gastrointestinalen pathogenen
WO2024161179A1 (en) 2023-01-31 2024-08-08 Mobidiag Oy Compositions and methods for detecting stx nucleic acids
WO2024192338A1 (en) 2023-03-16 2024-09-19 Gen-Probe Incorporated Compositions and methods for detecting gastrointestinal parasites
EP4455304A1 (de) 2023-04-28 2024-10-30 Mobidiag Oy Kontrollen für nukleinsäureamplifikationsverfahren
EP4455303A1 (de) 2023-04-28 2024-10-30 Mobidiag Oy Kontrollen für nukleinsäureamplifikationsverfahren
EP4454758A1 (de) 2023-04-28 2024-10-30 Mobidiag Oy Kontrollen für nukleinsäureamplifikationsverfahren
WO2024233375A1 (en) 2023-05-05 2024-11-14 Gen-Probe Incorporated Method and system for improving specificity of analyte detection using real-time nucleic acid amplification
WO2026050332A1 (en) 2024-08-29 2026-03-05 Gen-Probe Incorporated Methods and compositions for amplifying and/or detecting rotavirus nucleic acids

Family Cites Families (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060237A (en) 1985-02-26 2000-05-09 Biostar, Inc. Devices and methods for optical detection of nucleic acid hybridization
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
EP0232967B1 (de) 1986-01-10 1993-04-28 Amoco Corporation Kompetitiver homogener Test
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US6150517A (en) 1986-11-24 2000-11-21 Gen-Probe Methods for making oligonucleotide probes for the detection and/or quantitation of non-viral organisms
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
IE72468B1 (en) 1987-07-31 1997-04-09 Univ Leland Stanford Junior Selective amplification of target polynucleotide sequences
US6090591A (en) 1987-07-31 2000-07-18 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
US6031091A (en) 1987-09-21 2000-02-29 Gen-Probe Incorporated Non-nucleotide linking reagents for nucleotide probes
US5283174A (en) 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5585481A (en) 1987-09-21 1996-12-17 Gen-Probe Incorporated Linking reagents for nucleotide probes
US5030557A (en) 1987-11-24 1991-07-09 Ml Technology Venture Means and method for enhancing nucleic acid hybridization
JP2650159B2 (ja) 1988-02-24 1997-09-03 アクゾ・ノベル・エヌ・ベー 核酸増幅方法
CA1340807C (en) * 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5130238A (en) * 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
IE66597B1 (en) 1989-05-10 1996-01-24 Akzo Nv Method for the synthesis of ribonucleic acid (RNA)
US5766849A (en) * 1989-07-11 1998-06-16 Gen-Probe Incorporated Methods of amplifying nucleic acids using promoter-containing primer sequence
CA2020958C (en) * 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5539082A (en) 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US5169766A (en) 1991-06-14 1992-12-08 Life Technologies, Inc. Amplification of nucleic acid molecules
EP0566751B1 (de) 1992-03-23 1996-01-10 F. Hoffmann-La Roche Ag Verfahren zum DNS-Nachweis
AU681082B2 (en) 1992-05-06 1997-08-21 Gen-Probe Incorporated Nucleic acid sequence amplification method, composition and kit
CA2137563C (en) 1992-06-08 2005-06-28 Thomas B. Ryder Preparation of nucleic acid from mononuclear cells
US5339491A (en) 1992-11-06 1994-08-23 United Technologies Automotive, Inc. Sealed retainer grommet
KR100189229B1 (ko) 1993-07-23 1999-06-01 다니엘 엘. 캐시앙, 헨리 엘. 노르호프 핵산 증폭을 강화하는 방법
US5925517A (en) * 1993-11-12 1999-07-20 The Public Health Research Institute Of The City Of New York, Inc. Detectably labeled dual conformation oligonucleotide probes, assays and kits
JP3866762B2 (ja) 1993-11-29 2007-01-10 ジェン−プローブ・インコーポレイテッド 広範な生物からの核酸抽出法
FR2721945B1 (fr) * 1994-07-04 1996-10-18 David Fabrice Accroissement genique, un procede d'amplicication genique isotherme et ses applications
JP3189000B2 (ja) 1994-12-01 2001-07-16 東ソー株式会社 特定核酸配列の検出方法
DE69534217T2 (de) 1994-12-09 2006-01-12 Wakunaga Seiyaku K.K. Verfahren zur hemmung von nichtspezifischer hybridisierung in primerverlängerungsreaktionen
US5556771A (en) 1995-02-10 1996-09-17 Gen-Probe Incorporated Stabilized compositions of reverse transcriptase and RNA polymerase for nucleic acid amplification
US5710029A (en) 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
JPH0965880A (ja) 1995-08-29 1997-03-11 Hitachi Ltd Ｄｎａ解析法
AU713667B2 (en) 1996-04-12 1999-12-09 Phri Properties, Inc. Detection probes, kits and assays
US6117635A (en) * 1996-07-16 2000-09-12 Intergen Company Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon
US6130038A (en) 1996-07-16 2000-10-10 Gen-Probe Incorporated Method for amplifying target nucleic acids using modified primers
US6025133A (en) * 1996-12-30 2000-02-15 Gen-Probe Incorporated Promoter-sequestered oligonucleoside and method of use
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
US5849497A (en) 1997-04-03 1998-12-15 The Research Foundation Of State University Of New York Specific inhibition of the polymerase chain reaction using a non-extendable oligonucleotide blocker
US6534273B2 (en) 1997-05-02 2003-03-18 Gen-Probe Incorporated Two-step hybridization and capture of a polynucleotide
US6794499B2 (en) 1997-09-12 2004-09-21 Exiqon A/S Oligonucleotide analogues
AU762728B2 (en) 1998-07-02 2003-07-03 Gen-Probe Incorporated Molecular torches
US6303305B1 (en) 1999-03-30 2001-10-16 Roche Diagnostics, Gmbh Method for quantification of an analyte
EP1055734B1 (de) 1999-05-24 2004-10-13 Tosoh Corporation Methode zum Nachweis von Ribonukleinsäuren
WO2000071652A2 (en) * 1999-05-26 2000-11-30 The Procter & Gamble Company Detergent compositions comprising polymeric suds volume and suds duration enhancers
US6692918B2 (en) * 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
US6582938B1 (en) * 2001-05-11 2003-06-24 Affymetrix, Inc. Amplification of nucleic acids
JP2004513617A (ja) 2000-06-26 2004-05-13 ニューゲン　テクノロジーズ，　インコーポレイテッド 転写に基づく核酸増幅のための方法および組成物
US6946251B2 (en) * 2001-03-09 2005-09-20 Nugen Technologies, Inc. Methods and compositions for amplification of RNA sequences using RNA-DNA composite primers
US7214780B2 (en) 2001-11-02 2007-05-08 Gen-Probe Incorporated Probes, compositions and kits for determining the presence of Mycoplasma pneuomoniae in a test sample
CA2480525A1 (en) 2002-03-29 2003-10-09 Nugen Technologies, Inc. Single primer isothermal nucleic acid amplification-enhanced analyte detection and quantification
JP2004154088A (ja) 2002-11-08 2004-06-03 Sysmex Corp Ｃｅａ検出のための核酸増幅用プライマーおよび該プライマーを用いた検査方法
EP1576188B1 (de) * 2002-11-21 2008-10-15 Epicentre Technologies Verfahren zur verwendung von riboprimern zur strangverdrängungsreplikation von zielsequenzen
US7374885B2 (en) 2004-08-27 2008-05-20 Gen-Probe Incorporated Single-primer nucleic acid amplification methods
US7713697B2 (en) * 2004-08-27 2010-05-11 Gen-Probe Incorporated Methods and kits for amplifying DNA
US7833716B2 (en) 2006-06-06 2010-11-16 Gen-Probe Incorporated Tagged oligonucleotides and their use in nucleic acid amplification methods
PL2017356T3 (pl) * 2006-06-06 2012-03-30 Gen Probe Inc Znakowane oligonukleotydy i ich zastosowanie w sposobach amplifikacji kwasu nukleinowego
US20080131875A1 (en) 2006-06-07 2008-06-05 Third Wave Technologies, Inc. Multiplex assays
WO2008045251A2 (en) 2006-10-04 2008-04-17 Third Wave Technologies, Inc. Snap-back primers and detectable hairpin structures
CA2678799A1 (en) * 2007-03-01 2008-09-12 Gen-Probe Incorporated Methods and kits for amplifying dna
US8183359B2 (en) 2007-03-01 2012-05-22 Gen-Probe Incorporated Kits for amplifying DNA

Also Published As

Publication number Publication date
EP2071031A1 (de) 2009-06-17
CA2957197C (en) 2017-12-12
CA2898814A1 (en) 2006-03-09
US7939260B2 (en) 2011-05-10
EP1786916A4 (de) 2008-09-24
CA2980050A1 (en) 2006-03-09
EP1970454A3 (de) 2008-10-01
US7696337B2 (en) 2010-04-13
AU2005280162B2 (en) 2012-04-26
EP2071031B1 (de) 2013-10-09
WO2006026388A3 (en) 2007-01-18
CA2577122C (en) 2017-06-13
CA2898814C (en) 2015-12-29
CA2980050C (en) 2018-01-23
JP2008511327A (ja) 2008-04-17
AU2005280162A1 (en) 2006-03-09
WO2006026388A2 (en) 2006-03-09
CA2577122A1 (en) 2006-03-09
US20060046265A1 (en) 2006-03-02
US7374885B2 (en) 2008-05-20
EP1975242B1 (de) 2011-03-02
EP1975242A1 (de) 2008-10-01
EP1786916B1 (de) 2013-05-08
CA2957197A1 (en) 2006-03-09
JP4861324B2 (ja) 2012-01-25
EP1970454A2 (de) 2008-09-17
EP1970454B1 (de) 2012-09-19
US20070299254A1 (en) 2007-12-27
EP1786916A2 (de) 2007-05-23
DE602005026730D1 (de) 2011-04-14
US20090170168A1 (en) 2009-07-02

Similar Documents

Publication Publication Date Title
ATE500344T1 (de) Einfach-primernukleinsäuren-erweiterungsverfahr n
JP2008511327A5 (de)
US9255291B2 (en) Oligonucleotide ligation methods for improving data quality and throughput using massively parallel sequencing
JP4903725B2 (ja) 二重特異性オリゴヌクレオチドを使用した方法及び二重特異性オリゴヌクレオチド
KR101243266B1 (ko) 이중 특이성 올리고뉴클레오타이드를 사용한 방법 및 이중 특이성 올리고뉴클레오타이드
JP2012505641A5 (de)
EP1871897B1 (de) Verfahren zur herstellung von oligonukleotiden
JP2010519896A5 (de)
CA2985631A1 (en) Allele-specific amplification using a composition of overlapping non-allele-specific primer and allele-specific blocker oligonucleotides
KR900018376A (ko) 리보핵산(rna)의 합성방법
CA2639819A1 (en) Selective terminal tagging of nucleic acids
WO2003051901A3 (en) Pseudonucleotide comprising an intercalator
CN106795569B (zh) 减少引物二聚体扩增的方法
WO2004040019A1 (ja) 核酸の増幅法
CN109328235A (zh) 一步逆转录模板转换pcr
EP1047794A2 (de) Verfahren zum nachweis von nukleinsäuresequenzen
US20180016632A1 (en) System and method for transposase-mediated amplicon sequencing
US7943347B2 (en) Nucleic acid amplification method
JP2009504192A5 (de)
WO2004046378A3 (de) Microarray-basiertes verfahren zur amplifikation und detektion von nukleinsäuren in einem kontinuierlichen prozess
EP3252168B1 (de) Pcr-primer im zusammenhang mit komplementärer nukleotidsequenz oder komplementärer nukleotidsequenz mit fehlangepassten nukleotiden und verfahren zur amplifikation von nukleinsäure damit
US7501254B2 (en) Methods and compositions for amplification and capture of nucleic acid sequences
KR20140129644A (ko) Ｄｎａ 제한효소에 의해 활성 조절이 가능한 프라이머 및 이를 이용한 유전자 증폭방법 그리고 이러한 프라이머의 설계방법
WO2008143367A1 (en) Haplotyping method by multiplex amplification
JP2003199568A (ja) Ｄｎａ増幅反応の効率向上方法

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties