ATE501731T1 - Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen - Google Patents

Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen

Info

Publication number
ATE501731T1
ATE501731T1 AT05819741T AT05819741T ATE501731T1 AT E501731 T1 ATE501731 T1 AT E501731T1 AT 05819741 T AT05819741 T AT 05819741T AT 05819741 T AT05819741 T AT 05819741T AT E501731 T1 ATE501731 T1 AT E501731T1
Authority
AT
Austria
Prior art keywords
methods
compositions
melanocortin receptor
mimetibodies
binding
Prior art date
Application number
AT05819741T
Other languages
English (en)
Inventor
Mark Cunningham
Vedrana Stojanovic-Susulic
Karyn O'neil
Chichi Huang
Jeffrey Luo
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Application granted granted Critical
Publication of ATE501731T1 publication Critical patent/ATE501731T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68Melanocyte-stimulating hormone [MSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05819741T 2004-10-25 2005-10-25 Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen ATE501731T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62196004P 2004-10-25 2004-10-25
PCT/US2005/038431 WO2006047535A2 (en) 2004-10-25 2005-10-25 Melanocortin receptor binding mimetibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
ATE501731T1 true ATE501731T1 (de) 2011-04-15

Family

ID=36228385

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05819741T ATE501731T1 (de) 2004-10-25 2005-10-25 Melanocortin-rezeptor-bindende mimetibodies, zusammensetzungen, verfahren und verwendungen

Country Status (28)

Country Link
US (1) US20060105951A1 (de)
EP (1) EP1812046B1 (de)
JP (1) JP2008517605A (de)
KR (1) KR101255140B1 (de)
CN (1) CN101437540B (de)
AT (1) ATE501731T1 (de)
AU (1) AU2005299440B2 (de)
BR (1) BRPI0518411A2 (de)
CA (1) CA2585287A1 (de)
CY (1) CY1111486T1 (de)
DE (1) DE602005026970D1 (de)
DK (1) DK1812046T3 (de)
EA (1) EA200700944A1 (de)
EC (1) ECSP077416A (de)
ES (1) ES2363023T3 (de)
HR (1) HRP20110405T1 (de)
IL (1) IL182683A0 (de)
MA (1) MA28943B1 (de)
ME (1) ME01234B (de)
MX (1) MX2007004974A (de)
NO (1) NO20072499L (de)
PL (1) PL1812046T3 (de)
PT (1) PT1812046E (de)
RS (1) RS51789B (de)
SI (1) SI1812046T1 (de)
TN (1) TNSN07157A1 (de)
WO (1) WO2006047535A2 (de)
ZA (1) ZA200704260B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
WO2009151383A1 (en) * 2008-06-09 2009-12-17 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for the treatment of obesity and other diseases associated with melanocortin receptor function
KR101687037B1 (ko) 2008-06-09 2016-12-15 팔라틴 테크놀로지스 인코포레이티드 성기능 장애 치료용 멜라노코르틴 수용체-특이적 펩티드
US8614185B2 (en) * 2009-05-04 2013-12-24 Centocor Ortho Biotech Inc. Fusion proteins of alpha-MSH derivatives and Fc
EP2440572B1 (de) 2009-06-08 2017-04-05 Palatin Technologies, Inc. Lactam-gebrückte melanocortinrezeptorspezifische peptide
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
CA2761607C (en) 2009-06-08 2018-09-04 Yi-Qun Shi Melanocortin receptor-specific peptides
BR112012011780A2 (pt) 2009-11-23 2019-09-24 Palatin Technologies, Inc peptídeo linear,composição farmacêutica,métodopara tratamento de umadoença,indicação,condição ou sídrome mediadsa por receptor de melanocortina emum mamífero humano ou não humano e método para tratamento de uma condição responsiva ás alterações em função de receptor de melanocortina em um mamifero humano ou não humano
JP5999702B2 (ja) 2009-11-23 2016-09-28 パラティン テクノロジーズ, インコーポレイテッドPalatin Technologies, Inc. メラノコルチン−1受容体特異的環状ペプチド
JP2020141710A (ja) * 2011-07-06 2020-09-10 ゲンマブ エー/エス 抗体重鎖のc末端の修飾による補体依存性細胞傷害の調節
WO2020177627A1 (zh) * 2019-03-02 2020-09-10 上海一宸医药科技有限公司 一种双特异抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1137340A4 (de) * 1998-12-09 2005-12-21 Eleanor Roosevelt Inst Zusammensetzung und verfahren zur regulation des körpergewichtes und damit zusammenhängender zustände
AU7593001A (en) * 2000-07-14 2002-01-30 Zycos Inc Alpha-msh related compounds and methods of use
CA2490409A1 (en) * 2002-06-28 2004-01-08 Centocor, Inc. Mammalian ch1 deleted mimetibodies, compositions, methods and uses
US7241733B2 (en) * 2002-06-28 2007-07-10 Centocor, Inc. Mammalian EPO mimetic CH1 deleted mimetibodies, compositions, methods and uses
US20070135338A1 (en) * 2004-03-31 2007-06-14 Karyn O'neil Human GLP-1 mimetibodies, compositions, methods and uses

Also Published As

Publication number Publication date
AU2005299440A1 (en) 2006-05-04
DK1812046T3 (da) 2011-06-06
US20060105951A1 (en) 2006-05-18
EP1812046A4 (de) 2009-11-11
ME01234B (me) 2013-06-20
EP1812046B1 (de) 2011-03-16
EP1812046A2 (de) 2007-08-01
HK1106445A1 (en) 2008-03-14
RS51789B (sr) 2011-12-31
MX2007004974A (es) 2007-10-17
DE602005026970D1 (de) 2011-04-28
MA28943B1 (fr) 2007-10-01
ZA200704260B (en) 2009-03-25
ES2363023T3 (es) 2011-07-19
IL182683A0 (en) 2007-09-20
CA2585287A1 (en) 2006-05-04
PT1812046E (pt) 2011-06-28
HRP20110405T1 (hr) 2011-06-30
KR20070085416A (ko) 2007-08-27
ECSP077416A (es) 2007-05-30
WO2006047535A2 (en) 2006-05-04
CN101437540A (zh) 2009-05-20
AU2005299440B2 (en) 2011-12-15
PL1812046T3 (pl) 2011-08-31
KR101255140B1 (ko) 2013-04-22
EA200700944A1 (ru) 2008-04-28
BRPI0518411A2 (pt) 2008-11-18
WO2006047535A3 (en) 2008-09-04
JP2008517605A (ja) 2008-05-29
CY1111486T1 (el) 2015-08-05
TNSN07157A1 (en) 2008-11-21
NO20072499L (no) 2007-07-16
SI1812046T1 (sl) 2011-06-30
CN101437540B (zh) 2012-12-19

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