PL1812046T3 - Przeciwciała naśladowcze wiążące receptor melanokortyny, kompozycje, sposoby i zastosowania - Google Patents

Przeciwciała naśladowcze wiążące receptor melanokortyny, kompozycje, sposoby i zastosowania

Info

Publication number
PL1812046T3
PL1812046T3 PL05819741T PL05819741T PL1812046T3 PL 1812046 T3 PL1812046 T3 PL 1812046T3 PL 05819741 T PL05819741 T PL 05819741T PL 05819741 T PL05819741 T PL 05819741T PL 1812046 T3 PL1812046 T3 PL 1812046T3
Authority
PL
Poland
Prior art keywords
methods
receptor binding
compositions
melanocortin receptor
mimetibodies
Prior art date
Application number
PL05819741T
Other languages
English (en)
Inventor
Mark Cunningham
Vedrana Stojanovic-Susulic
Karyn O'neil
Chichi Huang
Jeffrey Luo
Original Assignee
Centocor Ortho Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Ortho Biotech Inc filed Critical Centocor Ortho Biotech Inc
Publication of PL1812046T3 publication Critical patent/PL1812046T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1796—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL05819741T 2004-10-25 2005-10-25 Przeciwciała naśladowcze wiążące receptor melanokortyny, kompozycje, sposoby i zastosowania PL1812046T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62196004P 2004-10-25 2004-10-25
PCT/US2005/038431 WO2006047535A2 (en) 2004-10-25 2005-10-25 Melanocortin receptor binding mimetibodies, compositions, methods and uses
EP05819741A EP1812046B1 (en) 2004-10-25 2005-10-25 Melanocortin receptor binding mimetibodies, compositions, methods and uses

Publications (1)

Publication Number Publication Date
PL1812046T3 true PL1812046T3 (pl) 2011-08-31

Family

ID=36228385

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05819741T PL1812046T3 (pl) 2004-10-25 2005-10-25 Przeciwciała naśladowcze wiążące receptor melanokortyny, kompozycje, sposoby i zastosowania

Country Status (28)

Country Link
US (1) US20060105951A1 (pl)
EP (1) EP1812046B1 (pl)
JP (1) JP2008517605A (pl)
KR (1) KR101255140B1 (pl)
CN (1) CN101437540B (pl)
AT (1) ATE501731T1 (pl)
AU (1) AU2005299440B2 (pl)
BR (1) BRPI0518411A2 (pl)
CA (1) CA2585287A1 (pl)
CY (1) CY1111486T1 (pl)
DE (1) DE602005026970D1 (pl)
DK (1) DK1812046T3 (pl)
EA (1) EA200700944A1 (pl)
EC (1) ECSP077416A (pl)
ES (1) ES2363023T3 (pl)
HR (1) HRP20110405T1 (pl)
IL (1) IL182683A0 (pl)
MA (1) MA28943B1 (pl)
ME (1) ME01234B (pl)
MX (1) MX2007004974A (pl)
NO (1) NO20072499L (pl)
PL (1) PL1812046T3 (pl)
PT (1) PT1812046E (pl)
RS (1) RS51789B (pl)
SI (1) SI1812046T1 (pl)
TN (1) TNSN07157A1 (pl)
WO (1) WO2006047535A2 (pl)
ZA (1) ZA200704260B (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7910101B2 (en) * 2004-10-25 2011-03-22 Centocor, Inc. Melanocortin receptor binding mimetibodies, compositions, methods and uses
US7790671B2 (en) * 2005-10-07 2010-09-07 Codman & Shurtleff, Inc. Implantable pump for protein delivery for obesity control by drug infusion into the brain
AR072072A1 (es) * 2008-06-09 2010-08-04 Palatin Technologies Inc Peptidos especificos del receptor de melanocortina para el tratamiento de la obesidad / 669
EP2300036B1 (en) 2008-06-09 2017-04-05 Palatin Technologies, Inc. Melanocortin receptor-specific peptides for treatment of sexual dysfunction
US8614185B2 (en) * 2009-05-04 2013-12-24 Centocor Ortho Biotech Inc. Fusion proteins of alpha-MSH derivatives and Fc
BRPI1009644B1 (pt) 2009-06-08 2022-02-08 Palatin Technologies, Inc Peptídeo cíclico ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica e uso da composição farmacêutica
UY32690A (es) 2009-06-08 2011-01-31 Astrazeneca Ab Péptidos específicos para receptores de melanocortina
WO2010144341A2 (en) 2009-06-08 2010-12-16 Palatin Technologies, Inc. Lactam-bridged melanocortin receptor-specific peptides
EP2504351A4 (en) 2009-11-23 2013-10-30 Palatin Technologies Inc MELANOCORTIN-1 RECEPTOR-SPECIFIC LINEAR PEPTIDE
AU2010321738B2 (en) 2009-11-23 2016-07-14 Palatin Technologies, Inc. Melanocortin-1 receptor-specific cyclic peptides
JP2020141710A (ja) * 2011-07-06 2020-09-10 ゲンマブ エー/エス 抗体重鎖のc末端の修飾による補体依存性細胞傷害の調節
WO2020177627A1 (zh) * 2019-03-02 2020-09-10 上海一宸医药科技有限公司 一种双特异抗体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01005818A (es) * 1998-12-09 2003-07-21 Eleanor Rooseveltl Inst Composicion y metodo para la regulacion del peso del cuerpo y condiciones asociadas.
WO2002006316A2 (en) * 2000-07-14 2002-01-24 Zycos, Inc. Alpha-msh related compounds and methods of use
WO2004002417A2 (en) * 2002-06-28 2004-01-08 Centocor, Inc. Mammalian ch1 deleted mimetibodies, compositions, methods and uses
US7241733B2 (en) * 2002-06-28 2007-07-10 Centocor, Inc. Mammalian EPO mimetic CH1 deleted mimetibodies, compositions, methods and uses
EP1750754A4 (en) * 2004-03-31 2010-09-22 Centocor Ortho Biotech Inc HUMAN GLP-1 MIMETIC BODIES, COMPOSITIONS, METHODS AND USES

Also Published As

Publication number Publication date
WO2006047535A2 (en) 2006-05-04
ATE501731T1 (de) 2011-04-15
HK1106445A1 (en) 2008-03-14
EP1812046B1 (en) 2011-03-16
PT1812046E (pt) 2011-06-28
SI1812046T1 (sl) 2011-06-30
ZA200704260B (en) 2009-03-25
CA2585287A1 (en) 2006-05-04
US20060105951A1 (en) 2006-05-18
WO2006047535A3 (en) 2008-09-04
IL182683A0 (en) 2007-09-20
RS51789B (sr) 2011-12-31
BRPI0518411A2 (pt) 2008-11-18
KR101255140B1 (ko) 2013-04-22
EA200700944A1 (ru) 2008-04-28
CY1111486T1 (el) 2015-08-05
HRP20110405T1 (hr) 2011-06-30
AU2005299440B2 (en) 2011-12-15
DK1812046T3 (da) 2011-06-06
CN101437540B (zh) 2012-12-19
CN101437540A (zh) 2009-05-20
NO20072499L (no) 2007-07-16
ECSP077416A (es) 2007-05-30
JP2008517605A (ja) 2008-05-29
MA28943B1 (fr) 2007-10-01
ME01234B (me) 2013-06-20
KR20070085416A (ko) 2007-08-27
DE602005026970D1 (de) 2011-04-28
EP1812046A2 (en) 2007-08-01
MX2007004974A (es) 2007-10-17
TNSN07157A1 (en) 2008-11-21
EP1812046A4 (en) 2009-11-11
ES2363023T3 (es) 2011-07-19
AU2005299440A1 (en) 2006-05-04

Similar Documents

Publication Publication Date Title
ZA200704260B (en) Melanocortin receptor binding mimetibodies, compositions, methods and uses
WO2007041635A3 (en) Fc variants with optimized fc receptor binding properties
TW200611910A (en) Interferon-alpha polypeptides and conjugates
HRP20190220T1 (hr) Anti-il-23 protutijela, pripravci, postupci i upotrebe
WO2006083276A3 (en) Interferon-alpha polypeptides and conjugates
WO2007087139A3 (en) MESENCHYMAL STEM CELLS EXPRESSING TNF-α RECEPTOR
IL236427A0 (en) Human anti-23-il antibodies, preparations, methods and uses
TW200631594A (en) Toll like receptor 3 antagonists, methods and uses
IL189555A0 (en) Compositions of cells enriched for combinations of various stem and progenitor cell populations, methods of use thereof and methods of private banking thereof
MX2010007716A (es) Combinacion de una proteina de fusion del anticuerpo-il-2 de anti-edb fibronectina y una molecula que se une a celulas b, progenitores de la celula b y/o sus contrapartes cancerigenas.
EP1617802A4 (en) CNGH0010 SPECIFIC POLYNUCLEOTIDES, POLYPEPTIDES, ANTIBODIES, COMPOSITIONS, METHODS AND USES
EP2214690A4 (en) THE MELANOCORTIN RECEPTOR BINDING MIMIC BODIES, COMPOSITIONS, PROCESSES AND USES
WO2007044083A3 (en) Evolved interferon-alpha polypeptides
TW200745159A (en) IL-6 binding proteins
WO2006018650A3 (en) Method of in vitro polypeptide selection using the arc dna binding domain fused to the polypeptide to be selected
MX296535B (es) Enzima laccasa novedosa y uso de la misma.
TW200711846A (en) Composite materials and methods of making the same
EP1828237A4 (en) HUMAN CANCER SUPPRESSOR GENE, PROTEIN ENCODED THEREIN, EXPRESSION VECTOR CONTAINING THE GENE, AND CELL TRANSFORMED BY THE VECTOR
WO2007056760A3 (en) Hcv-reactive t cell receptors
SG158098A1 (en) Toll like receptor 3 antagonists, methods and uses
AU2014210609B9 (en) Novel activin receptor and uses thereof
WO2005082088A3 (en) Functional genomics and gene trapping in haploid or hypodiploid cells
WO2005026207A3 (en) Adipocyte complement related protein zacrp12
GB2418913C (en) Improved peat substitute.
EP1844065A4 (en) POLYPEPTIDE WITH PYRIDOXIN BIOSYNTHESIS FUNCTION, POLYNUCLEOTIDE FOR CODING THE POLYPEPTIDE AND THEIR USE