ATE502653T1 - Verfahren zur herstellung einer piroxicam:beta- cyclodextrin-einschlussverbindung - Google Patents
Verfahren zur herstellung einer piroxicam:beta- cyclodextrin-einschlussverbindungInfo
- Publication number
- ATE502653T1 ATE502653T1 AT05774046T AT05774046T ATE502653T1 AT E502653 T1 ATE502653 T1 AT E502653T1 AT 05774046 T AT05774046 T AT 05774046T AT 05774046 T AT05774046 T AT 05774046T AT E502653 T1 ATE502653 T1 AT E502653T1
- Authority
- AT
- Austria
- Prior art keywords
- piroxicam
- beta
- inclusion compound
- producing
- cyclodextrin inclusion
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 2
- 239000001116 FEMA 4028 Substances 0.000 title abstract 2
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 title abstract 2
- 235000011175 beta-cyclodextrine Nutrition 0.000 title abstract 2
- 229960004853 betadex Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- QYSPLQLAKJAUJT-UHFFFAOYSA-N piroxicam Chemical compound OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 QYSPLQLAKJAUJT-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002702 piroxicam Drugs 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960000074 biopharmaceutical Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 238000001694 spray drying Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Nanotechnology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04018261 | 2004-08-02 | ||
| PCT/EP2005/008105 WO2006013039A2 (en) | 2004-08-02 | 2005-07-26 | A process for the preparation of a piroxicam: betacyclodextrin inclusion compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE502653T1 true ATE502653T1 (de) | 2011-04-15 |
Family
ID=35502714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05774046T ATE502653T1 (de) | 2004-08-02 | 2005-07-26 | Verfahren zur herstellung einer piroxicam:beta- cyclodextrin-einschlussverbindung |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090012284A1 (de) |
| EP (1) | EP1793862B1 (de) |
| JP (1) | JP2008508332A (de) |
| KR (1) | KR20070038109A (de) |
| CN (1) | CN101123989B (de) |
| AT (1) | ATE502653T1 (de) |
| AU (1) | AU2005268972A1 (de) |
| DE (1) | DE602005027092D1 (de) |
| IL (1) | IL181101A0 (de) |
| MA (1) | MA28849B1 (de) |
| MX (1) | MX2007001237A (de) |
| NO (1) | NO20070669L (de) |
| PL (1) | PL1793862T3 (de) |
| PT (1) | PT1793862E (de) |
| TN (1) | TNSN07012A1 (de) |
| WO (1) | WO2006013039A2 (de) |
| ZA (1) | ZA200700946B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101491529B (zh) * | 2009-01-23 | 2011-04-06 | 上海微丸医药开发有限公司 | 一种吡罗昔康β-环糊精包合物微丸胶囊的制备方法 |
| BR102012009317B1 (pt) * | 2012-04-20 | 2022-05-31 | Universidade Federal De Minas Gerais - Ufmg | Processo de preparação de compostos de inclusão envolvendo ciclodextrinas e fármacos, usando um sistema de fluxo contínuo |
| WO2014161131A1 (en) * | 2013-04-01 | 2014-10-09 | Arissa Pharma | PREPARING AMORPHOUS MELOXICAM-β-CYCLODEXTRIN INCLUSION COMPLEX VIA SPRAY DRYING PROCESS |
| WO2015001133A1 (en) * | 2013-12-12 | 2015-01-08 | Synthon B.V. | Pharmaceutical composition comprising amorphous ivabradine |
| EP3302781B1 (de) * | 2015-05-29 | 2020-09-16 | Givaudan S.A. | Sprühtrocknung |
| US20170056253A1 (en) * | 2015-08-28 | 2017-03-02 | Fitesa Nonwoven, Inc. | Absorbent Article Having A High Content Of Bio-Based Materials |
| JP7138643B2 (ja) * | 2017-01-09 | 2022-09-16 | サイファーム ソシエテ ア レスポンサビリテ リミテ | 水溶性フォルスコリンの新規製造法 |
| CN111148491B (zh) * | 2017-09-21 | 2023-04-07 | 宝洁公司 | 吸收制品 |
| CN110575550A (zh) * | 2019-08-13 | 2019-12-17 | 大梆(沈阳)动物保健有限公司 | 一种遮蔽兽用复方中药不良嗅味的方法 |
| CN112471565A (zh) * | 2020-12-18 | 2021-03-12 | 鲁南制药集团股份有限公司 | 一种挥发油喷雾研磨包合设备 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1196033B (it) * | 1984-02-22 | 1988-11-10 | Chiesi Farma Spa | Composto ad attivita' antiinfiammatoria ottenuto per complessazione con beta-ciclodestrina e relative formulazioni farmaceutiche |
| IT1204725B (it) * | 1987-06-17 | 1989-03-10 | Edmond Pharma Srl | Complessi di inclusione del dipiridamolo con ciclodestrine |
| US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| ZA941544B (en) * | 1993-03-05 | 1994-10-31 | Hexal Pharma Gmbh | Crystalline cyclodextrin complexes of ranitidine hydrochloride, process for their preparation and pharmaceutical compositions containing the same. |
| KR20030041577A (ko) * | 2001-11-20 | 2003-05-27 | 디디에스텍주식회사 | 난용성 약물과 치환된 시클로덱스트린을 함유하는고체분산체 및 이를 함유하는 약제학적 조성물 |
| WO2006011044A1 (en) * | 2004-07-22 | 2006-02-02 | Pfizer Products Inc. | Amorphous cyclodextrin compositions |
-
2005
- 2005-07-26 US US11/659,020 patent/US20090012284A1/en not_active Abandoned
- 2005-07-26 EP EP05774046A patent/EP1793862B1/de not_active Expired - Lifetime
- 2005-07-26 KR KR1020077000995A patent/KR20070038109A/ko not_active Withdrawn
- 2005-07-26 ZA ZA200700946A patent/ZA200700946B/xx unknown
- 2005-07-26 JP JP2007524228A patent/JP2008508332A/ja active Pending
- 2005-07-26 PL PL05774046T patent/PL1793862T3/pl unknown
- 2005-07-26 WO PCT/EP2005/008105 patent/WO2006013039A2/en not_active Ceased
- 2005-07-26 DE DE602005027092T patent/DE602005027092D1/de not_active Expired - Lifetime
- 2005-07-26 AU AU2005268972A patent/AU2005268972A1/en not_active Abandoned
- 2005-07-26 AT AT05774046T patent/ATE502653T1/de active
- 2005-07-26 CN CN2005800256534A patent/CN101123989B/zh not_active Expired - Fee Related
- 2005-07-26 PT PT05774046T patent/PT1793862E/pt unknown
- 2005-07-26 MX MX2007001237A patent/MX2007001237A/es unknown
-
2007
- 2007-01-16 TN TNP2007000012A patent/TNSN07012A1/en unknown
- 2007-01-31 NO NO20070669A patent/NO20070669L/no not_active Application Discontinuation
- 2007-02-01 IL IL181101A patent/IL181101A0/en unknown
- 2007-03-02 MA MA29734A patent/MA28849B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005027092D1 (de) | 2011-05-05 |
| ZA200700946B (en) | 2008-06-25 |
| PL1793862T3 (pl) | 2011-08-31 |
| PT1793862E (pt) | 2011-04-08 |
| HK1116054A1 (en) | 2008-12-19 |
| WO2006013039A2 (en) | 2006-02-09 |
| KR20070038109A (ko) | 2007-04-09 |
| NO20070669L (no) | 2007-05-02 |
| AU2005268972A1 (en) | 2006-02-09 |
| MX2007001237A (es) | 2007-04-18 |
| EP1793862A2 (de) | 2007-06-13 |
| EP1793862B1 (de) | 2011-03-23 |
| JP2008508332A (ja) | 2008-03-21 |
| CN101123989B (zh) | 2010-12-15 |
| TNSN07012A1 (en) | 2008-06-02 |
| IL181101A0 (en) | 2007-07-04 |
| CN101123989A (zh) | 2008-02-13 |
| US20090012284A1 (en) | 2009-01-08 |
| MA28849B1 (fr) | 2007-09-03 |
| WO2006013039A3 (en) | 2007-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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