PL3565602T3 - Nowy sposób wytwarzania rozpuszczalnej w wodzie forskoliny - Google Patents

Nowy sposób wytwarzania rozpuszczalnej w wodzie forskoliny

Info

Publication number
PL3565602T3
PL3565602T3 PL18700143T PL18700143T PL3565602T3 PL 3565602 T3 PL3565602 T3 PL 3565602T3 PL 18700143 T PL18700143 T PL 18700143T PL 18700143 T PL18700143 T PL 18700143T PL 3565602 T3 PL3565602 T3 PL 3565602T3
Authority
PL
Poland
Prior art keywords
forskoline
soluble
producing
water
new method
Prior art date
Application number
PL18700143T
Other languages
English (en)
Inventor
Andreas Kubin
Original Assignee
SciPharm S.à r.l.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SciPharm S.à r.l. filed Critical SciPharm S.à r.l.
Publication of PL3565602T3 publication Critical patent/PL3565602T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
PL18700143T 2017-01-09 2018-01-09 Nowy sposób wytwarzania rozpuszczalnej w wodzie forskoliny PL3565602T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17150644 2017-01-09
PCT/EP2018/050447 WO2018127600A1 (en) 2017-01-09 2018-01-09 Novel process for preparing water soluble forskolin
EP18700143.3A EP3565602B1 (en) 2017-01-09 2018-01-09 Novel process for preparing water soluble forskolin

Publications (1)

Publication Number Publication Date
PL3565602T3 true PL3565602T3 (pl) 2021-09-13

Family

ID=57868023

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18700143T PL3565602T3 (pl) 2017-01-09 2018-01-09 Nowy sposób wytwarzania rozpuszczalnej w wodzie forskoliny

Country Status (18)

Country Link
US (1) US11234957B2 (pl)
EP (1) EP3565602B1 (pl)
JP (1) JP7138643B2 (pl)
KR (1) KR102583356B1 (pl)
CN (1) CN110325217B (pl)
CY (1) CY1124325T1 (pl)
DK (1) DK3565602T3 (pl)
ES (1) ES2872223T3 (pl)
HR (1) HRP20210863T1 (pl)
HU (1) HUE054617T2 (pl)
LT (1) LT3565602T (pl)
PL (1) PL3565602T3 (pl)
PT (1) PT3565602T (pl)
RS (1) RS61915B1 (pl)
SG (1) SG11201906321WA (pl)
SI (1) SI3565602T1 (pl)
SM (1) SMT202100499T1 (pl)
WO (1) WO2018127600A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7700133B2 (ja) 2020-01-23 2025-06-30 サイファーム ソシエテ ア レスポンサビリテ リミテ 7-デアセチル-フォルスコリンとpvpの複合体
EP4208026A1 (en) * 2020-09-01 2023-07-12 University of Iowa Research Foundation Dithiophosphate derivatives as hydrogen sulfide release chemicals for improving plant growth and crop yield

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199444B (en) * 1985-09-10 1990-02-28 Chinoin Gyogyszer Es Vegyeszet Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom
JP3040015B2 (ja) * 1991-08-21 2000-05-08 日研化学株式会社 フォルスコリンの包接化合物
IT1294205B1 (it) 1997-07-23 1999-03-24 Farmigea Spa Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive
US6884885B2 (en) * 2000-12-21 2005-04-26 Cerestar Holding B.V. Production of cyclodextrin complexes
GB0127677D0 (en) * 2001-11-19 2002-01-09 Vianex S A Inclusion complex
US7713940B2 (en) 2003-05-20 2010-05-11 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Water-soluble isoflavone composition, process for producing the same, and use thereof
US6960300B2 (en) 2003-09-08 2005-11-01 Sami Labs Limited Process for preparing water soluble diterpenes and their applications
ATE502653T1 (de) * 2004-08-02 2011-04-15 Chiesi Farma Spa Verfahren zur herstellung einer piroxicam:beta- cyclodextrin-einschlussverbindung
BRPI0705319A2 (pt) * 2007-07-23 2009-07-21 Uniao Brasileira De Educacao Manedora Da Pucrs processo para obtenção de um complexo solúvel de resveratrol e/ou seus derivados; complexo de resveratrol e/ou seus derivados; composição nutracêutica
EP2253627A1 (en) 2009-05-21 2010-11-24 ERREGIERRE S.p.A. Inclusion complex of raloxifene hydrochloride and beta-cyclodextrin.
CN103768616B (zh) * 2014-01-08 2015-08-05 中国科学院昆明植物研究所 毛萼乙素环糊精包合物、含有该包合物的药物组合物、其制备方法及应用

Also Published As

Publication number Publication date
DK3565602T3 (da) 2021-06-07
SG11201906321WA (en) 2019-08-27
SI3565602T1 (sl) 2021-07-30
KR102583356B1 (ko) 2023-09-26
CY1124325T1 (el) 2022-07-22
LT3565602T (lt) 2021-06-25
PT3565602T (pt) 2021-05-26
HRP20210863T1 (hr) 2021-08-20
SMT202100499T1 (it) 2021-09-14
CN110325217B (zh) 2023-08-08
JP7138643B2 (ja) 2022-09-16
RS61915B1 (sr) 2021-06-30
US20210145791A1 (en) 2021-05-20
KR20190107690A (ko) 2019-09-20
EP3565602B1 (en) 2021-03-03
CN110325217A (zh) 2019-10-11
ES2872223T3 (es) 2021-11-02
WO2018127600A1 (en) 2018-07-12
EP3565602A1 (en) 2019-11-13
JP2020505339A (ja) 2020-02-20
HUE054617T2 (hu) 2021-09-28
US11234957B2 (en) 2022-02-01

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