ATE503494T1 - Epitop-zusammensetzung zur enterischen verabreichung hergestellt durch hydrolyse von antigenen strukturen mit chymotrypsin - Google Patents
Epitop-zusammensetzung zur enterischen verabreichung hergestellt durch hydrolyse von antigenen strukturen mit chymotrypsinInfo
- Publication number
- ATE503494T1 ATE503494T1 AT04740162T AT04740162T ATE503494T1 AT E503494 T1 ATE503494 T1 AT E503494T1 AT 04740162 T AT04740162 T AT 04740162T AT 04740162 T AT04740162 T AT 04740162T AT E503494 T1 ATE503494 T1 AT E503494T1
- Authority
- AT
- Austria
- Prior art keywords
- chymotrypsin
- hydrolysis
- epitopic
- composition
- enteric administration
- Prior art date
Links
- 108090000317 Chymotrypsin Proteins 0.000 title abstract 2
- 230000000890 antigenic effect Effects 0.000 title abstract 2
- 229960002376 chymotrypsin Drugs 0.000 title abstract 2
- 230000007062 hydrolysis Effects 0.000 title abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 title abstract 2
- CFYIUBWVKZQDOG-UHFFFAOYSA-N 4-[[2-[[2-[[1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-oxobutanoic acid Chemical compound C=1C=C([N+]([O-])=O)C=CC=1NC(=O)C(NC(=O)CNC(=O)CNC(=O)CCC(=O)O)CC1=CC=CC=C1 CFYIUBWVKZQDOG-UHFFFAOYSA-N 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010052779 Transplant rejections Diseases 0.000 abstract 1
- 208000030961 allergic reaction Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Lead Frames For Integrated Circuits (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03014020 | 2003-06-23 | ||
| US53062903P | 2003-12-19 | 2003-12-19 | |
| EP03029356 | 2003-12-19 | ||
| PCT/EP2004/006733 WO2004112833A1 (en) | 2003-06-23 | 2004-06-22 | Epitope composition for sublingual, buccal or enteric administration prepared by hydrolysis of antigenic structures with chymotrypsin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE503494T1 true ATE503494T1 (de) | 2011-04-15 |
Family
ID=43825131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04740162T ATE503494T1 (de) | 2003-06-23 | 2004-06-22 | Epitop-zusammensetzung zur enterischen verabreichung hergestellt durch hydrolyse von antigenen strukturen mit chymotrypsin |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20070292446A9 (de) |
| AT (1) | ATE503494T1 (de) |
| DE (1) | DE602004032025D1 (de) |
| DK (1) | DK1641488T3 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20170117562A (ko) | 2015-02-20 | 2017-10-23 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 혼합 알레르겐 조성물 및 그의 사용 방법 |
| US10149904B2 (en) | 2015-02-20 | 2018-12-11 | The Board Of Trusteees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US11452774B2 (en) | 2015-02-20 | 2022-09-27 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10143742B2 (en) | 2015-02-20 | 2018-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| US10166286B2 (en) | 2015-02-20 | 2019-01-01 | The Board Of Trustees Of The Leland Stanford Junior University | Mixed allergen compositions and methods for using the same |
| WO2019018529A1 (en) | 2017-07-18 | 2019-01-24 | Before Brands, Inc. | METHODS OF MAKING MIXED ALLERGEN COMPOSITIONS |
| AU2020213085A1 (en) | 2019-01-23 | 2021-08-12 | Société des Produits Nestlé S.A. | Methods for making mixed allergen compositions |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4215036A (en) * | 1978-08-15 | 1980-07-29 | Research Corporation | Modified grass pollen antigens |
| US5898037A (en) * | 1992-11-13 | 1999-04-27 | Marx; Alvin J. | Formulations of magnesium compounds for local application and methods of treatment using the same |
| JP3818680B2 (ja) * | 1994-05-12 | 2006-09-06 | サントリー株式会社 | アレルギー症状の予防又は改善剤 |
| SE9402089D0 (sv) * | 1994-06-14 | 1994-06-14 | Rudolf Valenta | Recombinant allergen, fragments thereof, corresponding recombinant DNA molecules, vectors and hosts containing the DNA molecules, diagnostic and therapeutic uses of said allergens and fragments |
| BE1011033A6 (fr) * | 1997-03-05 | 1999-04-06 | Univ Bruxelles | Composition pharmaceutique et/ou alimentaire pour le traitement de pathologies liees a un rejet de greffe, une reaction allergique ou auto-immune ou du cancer. |
| EP1219299B2 (de) * | 2000-12-28 | 2010-11-10 | Biomay Ag | Allergievakzine sowie ihre Herstellung |
| US6319679B1 (en) * | 2001-01-26 | 2001-11-20 | Board Of Regents, The University Of Texas System | PAS kinase |
-
2004
- 2004-06-22 DE DE602004032025T patent/DE602004032025D1/de not_active Expired - Lifetime
- 2004-06-22 DK DK04740162.5T patent/DK1641488T3/da active
- 2004-06-22 AT AT04740162T patent/ATE503494T1/de active
- 2004-06-22 US US10/561,175 patent/US20070292446A9/en not_active Abandoned
-
2014
- 2014-12-01 US US14/556,930 patent/US20150150956A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060147459A1 (en) | 2006-07-06 |
| US20150150956A1 (en) | 2015-06-04 |
| DE602004032025D1 (de) | 2011-05-12 |
| US20070292446A9 (en) | 2007-12-20 |
| DK1641488T3 (da) | 2011-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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