ATE335745T1 - Verfahren zur herstellung von protease hemmenden zwischenprodukten - Google Patents
Verfahren zur herstellung von protease hemmenden zwischenproduktenInfo
- Publication number
- ATE335745T1 ATE335745T1 AT02761678T AT02761678T ATE335745T1 AT E335745 T1 ATE335745 T1 AT E335745T1 AT 02761678 T AT02761678 T AT 02761678T AT 02761678 T AT02761678 T AT 02761678T AT E335745 T1 ATE335745 T1 AT E335745T1
- Authority
- AT
- Austria
- Prior art keywords
- intermediate products
- producing protease
- inhibiting intermediate
- present
- inhibiting
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 102000004580 Aspartic Acid Proteases Human genes 0.000 abstract 1
- 108010017640 Aspartic Acid Proteases Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- -1 cyclic alcohols Chemical class 0.000 abstract 1
- 238000010511 deprotection reaction Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32369201P | 2001-09-20 | 2001-09-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE335745T1 true ATE335745T1 (de) | 2006-09-15 |
Family
ID=23260324
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02761678T ATE335745T1 (de) | 2001-09-20 | 2002-09-16 | Verfahren zur herstellung von protease hemmenden zwischenprodukten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7145024B2 (de) |
| EP (1) | EP1465897B1 (de) |
| JP (1) | JP2005510467A (de) |
| AT (1) | ATE335745T1 (de) |
| AU (1) | AU2002326925A1 (de) |
| DE (1) | DE60213874T2 (de) |
| ES (1) | ES2265052T3 (de) |
| WO (1) | WO2003024974A2 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1532127T3 (da) * | 2002-06-27 | 2007-02-05 | Smithkline Beecham Corp | Fremstilling af stereoisomerer af (3alfa,3alfa/beta,6alfa/beta)hexahydrofuro(2,3-b)furan-3-ol |
| WO2004060895A1 (ja) * | 2002-12-27 | 2004-07-22 | Sumitomo Chemical Company, Limited | ヘキサヒドロフロフラノール誘導体の製造方法、その中間体及びその製造方法 |
| EP1638960A4 (de) * | 2003-06-27 | 2009-04-01 | Smithkline Beecham Corp | Herstellung chemischer verbindungen |
| ES2359949T3 (es) | 2006-11-09 | 2011-05-30 | Tibotec Pharmaceuticals | Métodos para preparar hexhidrofuro(2,3-b)furan-3-ol. |
| US8921415B2 (en) | 2009-01-29 | 2014-12-30 | Mapi Pharma Ltd. | Polymorphs of darunavir |
| EP2528923B1 (de) | 2010-01-28 | 2014-07-30 | Mapi Pharma Limited | Verfahren zur herstellung von darunavir und darunavir-zwischenprodukten |
| US9125625B2 (en) | 2010-06-10 | 2015-09-08 | The Regents Of The University Of California | Textile-based printable electrodes for electrochemical sensing |
| PT2643326T (pt) | 2010-11-23 | 2016-12-23 | Mylan Laboratories Ltd | Processo para a preparação de (3r,3as,6ar)-hexa-hidrofuro[2,3-b]furan-3-ol |
| JP2014533523A (ja) | 2011-09-02 | 2014-12-15 | ザ レジェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア | バイオセンシングおよび薬剤供給のためのマイクロ針アレイ |
| CN106977526A (zh) * | 2017-05-25 | 2017-07-25 | 河南省商业科学研究所有限责任公司 | 一种3,4‑二甲基噻吩[2,3‑b]并噻吩的合成方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6828894A (en) * | 1993-05-14 | 1994-12-12 | Merck & Co., Inc. | Hiv protease inhibitors |
| US5810766A (en) | 1995-02-28 | 1998-09-22 | Chiron Vision Corporation | Infusion/aspiration apparatus with removable cassette |
-
2002
- 2002-09-16 WO PCT/US2002/029315 patent/WO2003024974A2/en not_active Ceased
- 2002-09-16 ES ES02761678T patent/ES2265052T3/es not_active Expired - Lifetime
- 2002-09-16 AT AT02761678T patent/ATE335745T1/de not_active IP Right Cessation
- 2002-09-16 JP JP2003528821A patent/JP2005510467A/ja not_active Ceased
- 2002-09-16 US US10/490,186 patent/US7145024B2/en not_active Expired - Fee Related
- 2002-09-16 AU AU2002326925A patent/AU2002326925A1/en not_active Abandoned
- 2002-09-16 EP EP02761678A patent/EP1465897B1/de not_active Expired - Lifetime
- 2002-09-16 DE DE60213874T patent/DE60213874T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20040204595A1 (en) | 2004-10-14 |
| DE60213874T2 (de) | 2007-10-18 |
| DE60213874D1 (de) | 2006-09-21 |
| WO2003024974A3 (en) | 2004-07-29 |
| JP2005510467A (ja) | 2005-04-21 |
| WO2003024974A2 (en) | 2003-03-27 |
| US7145024B2 (en) | 2006-12-05 |
| AU2002326925A1 (en) | 2003-04-01 |
| EP1465897B1 (de) | 2006-08-09 |
| EP1465897A2 (de) | 2004-10-13 |
| ES2265052T3 (es) | 2007-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |