ATE506347T1 - Neue organische verbindung und verfahren zur herstellung einer mit radioaktivem halogen markierten organischen verbindung unter anwendung davon - Google Patents

Neue organische verbindung und verfahren zur herstellung einer mit radioaktivem halogen markierten organischen verbindung unter anwendung davon

Info

Publication number
ATE506347T1
ATE506347T1 AT06746390T AT06746390T ATE506347T1 AT E506347 T1 ATE506347 T1 AT E506347T1 AT 06746390 T AT06746390 T AT 06746390T AT 06746390 T AT06746390 T AT 06746390T AT E506347 T1 ATE506347 T1 AT E506347T1
Authority
AT
Austria
Prior art keywords
organic compound
radioactive halogen
producing
amino
syn
Prior art date
Application number
AT06746390T
Other languages
English (en)
Inventor
Masahito Toyama
Fumie Kurosaki
Akio Hayashi
Osamu Ito
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of ATE506347T1 publication Critical patent/ATE506347T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/40—2,5-Pyrrolidine-diones
    • C07D207/404—2,5-Pyrrolidine-diones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. succinimide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT06746390T 2005-05-23 2006-05-15 Neue organische verbindung und verfahren zur herstellung einer mit radioaktivem halogen markierten organischen verbindung unter anwendung davon ATE506347T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2005149186 2005-05-23
JP2006009643 2006-05-15

Publications (1)

Publication Number Publication Date
ATE506347T1 true ATE506347T1 (de) 2011-05-15

Family

ID=37451836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06746390T ATE506347T1 (de) 2005-05-23 2006-05-15 Neue organische verbindung und verfahren zur herstellung einer mit radioaktivem halogen markierten organischen verbindung unter anwendung davon

Country Status (14)

Country Link
US (1) US7910745B2 (de)
EP (1) EP1889834B1 (de)
JP (1) JP4989467B2 (de)
KR (1) KR101315152B1 (de)
CN (1) CN101180272B (de)
AT (1) ATE506347T1 (de)
AU (1) AU2006250594B2 (de)
CA (1) CA2608919C (de)
DE (1) DE602006021418D1 (de)
DK (1) DK1889834T3 (de)
ES (1) ES2364463T3 (de)
NO (1) NO20076411L (de)
TW (1) TWI410396B (de)
WO (1) WO2006126410A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2612187C (en) * 2005-06-23 2013-05-07 Emory University Stereoselective synthesis of amino acid analogs for tumor imaging
RU2428415C2 (ru) 2005-11-29 2011-09-10 Нихон Меди-Физикс Ко., Лтд. Соединение-предшественник органического соединения, меченного радиоактивным галогеном
PT2106808T (pt) 2006-12-21 2018-03-26 Nihon Mediphysics Co Ltd Agente de imagiologia de diagnóstico radioativo compreendendo ácido 1-amino-3-[18f]fluoro-ciclobutanocarboxílico
BRPI0720465B8 (pt) * 2006-12-27 2021-07-27 Nihon Mediphysics Co Ltd processo para produção de composto de precursor para composto orgânico marcado com halogênio radioativo
JP5258583B2 (ja) * 2007-02-13 2013-08-07 日本メジフィジックス株式会社 放射性画像診断剤の製造方法
JP5121349B2 (ja) * 2007-08-10 2013-01-16 株式会社トクヤマ アミノ酸の製造方法
CN102471235A (zh) * 2009-07-11 2012-05-23 拜耳医药股份有限公司 利用环烷基的放射性标记方法
WO2012055992A2 (en) 2010-10-28 2012-05-03 Ge Healthcare Limited Stabilisation of radiopharmaceutical precursors
GB201305687D0 (en) 2013-03-28 2013-05-15 Ge Healthcare Ltd Radiolabelling process
WO2018235535A1 (ja) * 2017-06-23 2018-12-27 日本メジフィジックス株式会社 放射性ハロゲン標識化合物の製造方法および放射性医薬の製造方法
EP4049993A4 (de) 2019-10-25 2022-11-09 Jilin Asymchem Pharmaceuticals Co., Ltd. Verfahren zur herstellung von trans-cyclobutan-phthalat und derivat davon
CN110724058A (zh) * 2019-10-25 2020-01-24 吉林凯莱英制药有限公司 反式环丁烷邻二羧酸酯及其衍生物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
FR2841554B1 (fr) * 2002-07-01 2008-01-18 Commissariat Energie Atomique Composes de maleimides marques, leur procede de preparation et leur utilisation pour le marquage de macromolecules
GB0229695D0 (en) 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids

Also Published As

Publication number Publication date
AU2006250594B2 (en) 2011-06-16
US7910745B2 (en) 2011-03-22
CN101180272B (zh) 2012-04-25
EP1889834B1 (de) 2011-04-20
DE602006021418D1 (de) 2011-06-01
TWI410396B (zh) 2013-10-01
EP1889834A1 (de) 2008-02-20
CN101180272A (zh) 2008-05-14
CA2608919C (en) 2012-11-20
WO2006126410A1 (ja) 2006-11-30
AU2006250594A1 (en) 2006-11-30
HK1117529A1 (en) 2009-01-16
TW200704630A (en) 2007-02-01
JPWO2006126410A1 (ja) 2008-12-25
DK1889834T3 (da) 2011-08-08
CA2608919A1 (en) 2006-11-30
NO20076411L (no) 2008-02-13
US20090105489A1 (en) 2009-04-23
KR101315152B1 (ko) 2013-10-07
EP1889834A4 (de) 2010-06-30
KR20080016557A (ko) 2008-02-21
JP4989467B2 (ja) 2012-08-01
ES2364463T3 (es) 2011-09-02

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