ATE507308T1 - M. tuberculosis offener leserahmen rv2660c und deren verwendung - Google Patents

M. tuberculosis offener leserahmen rv2660c und deren verwendung

Info

Publication number
ATE507308T1
ATE507308T1 AT08015511T AT08015511T ATE507308T1 AT E507308 T1 ATE507308 T1 AT E507308T1 AT 08015511 T AT08015511 T AT 08015511T AT 08015511 T AT08015511 T AT 08015511T AT E507308 T1 ATE507308 T1 AT E507308T1
Authority
AT
Austria
Prior art keywords
deletions
tuberculosis
bcg
isolates
rv2660c
Prior art date
Application number
AT08015511T
Other languages
English (en)
Inventor
Marcel Behr
Peter Small
Gary Schoolnik
Michael A Wilson
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Application granted granted Critical
Publication of ATE507308T1 publication Critical patent/ATE507308T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Data Exchanges In Wide-Area Networks (AREA)
  • Door And Window Frames Mounted To Openings (AREA)
  • Multicomponent Fibers (AREA)
  • Special Wing (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT08015511T 1998-08-25 1999-08-10 M. tuberculosis offener leserahmen rv2660c und deren verwendung ATE507308T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9793698P 1998-08-25 1998-08-25
US09/318,191 US6291190B1 (en) 1998-08-25 1999-05-25 Molecular differences between species of the M. tuberculosis complex

Publications (1)

Publication Number Publication Date
ATE507308T1 true ATE507308T1 (de) 2011-05-15

Family

ID=26793800

Family Applications (3)

Application Number Title Priority Date Filing Date
AT08015511T ATE507308T1 (de) 1998-08-25 1999-08-10 M. tuberculosis offener leserahmen rv2660c und deren verwendung
AT08017907T ATE473299T1 (de) 1998-08-25 1999-08-10 M. tb offener leserahmen rv2659c, und deren verwendung
AT99939702T ATE466100T1 (de) 1998-08-25 1999-08-10 Molekulare unterschiede innerhalb von spezies des m. tuberculosis-komplexes

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT08017907T ATE473299T1 (de) 1998-08-25 1999-08-10 M. tb offener leserahmen rv2659c, und deren verwendung
AT99939702T ATE466100T1 (de) 1998-08-25 1999-08-10 Molekulare unterschiede innerhalb von spezies des m. tuberculosis-komplexes

Country Status (9)

Country Link
US (6) US6291190B1 (de)
EP (3) EP2006395B1 (de)
AT (3) ATE507308T1 (de)
AU (1) AU5394699A (de)
DE (3) DE69942310D1 (de)
DK (3) DK2006395T3 (de)
ES (1) ES2343927T3 (de)
PT (2) PT2006395E (de)
WO (1) WO2000011214A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018574A1 (en) * 1998-08-25 2004-01-29 Marcel Behr Molecular differences between species of the M. tuberculosis complex
US6291190B1 (en) * 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
FR2791067B1 (fr) * 1999-03-16 2003-01-31 Pasteur Institut Sequence deletees chez m.bovis bcg/m.ou m.tuberculosis, procede de detection des mycobacteries utilisant ces sequences et vaccins
EP2087906A1 (de) 1999-05-04 2009-08-12 The University of Medicine and Dentistry of New Jersey Durch Mycobacterium tuberculosis und nicht durch BCG exprimierte Proteine und deren Verwendung als diagnostische Reagenzien und Impfstoffe
EP1377827A2 (de) * 2001-04-10 2004-01-07 NMI Naturwissenschaftliches und Medizinisches Institut an der Universität Tübingen in Reutlingen Stiftung Bürgerlichen Rechts Methode zur bestimmung von analytmolekülen in einer probe
US7758874B2 (en) * 2002-02-19 2010-07-20 Albert Einstein College Of Medicine Of Yeshiva University Attenuated Mycobacterium tuberculosis vaccines
AU2003209345A1 (en) * 2002-02-19 2003-09-09 Albert Einstein College Of Medicine Of Yeshiva University Attenuated mycobacterium tuberculosis vaccines
DE60219589T2 (de) * 2002-02-25 2008-02-14 Institut Pasteur Spezifisch vom Genom von Mycobacterium tuberculosis deletierte Sequenzen und deren Verwendung in der Diagnostik und als Vakzine
WO2003089462A2 (en) * 2002-04-16 2003-10-30 Jun Liu Tuberculosis vaccines including recombinant bcg strains expressing alanine dehydrogenase, serine dehydratase and/or glutamine synthetase
WO2003093307A2 (en) * 2002-04-27 2003-11-13 The Secretary Of State For Environment, Food And Rural Affairs Mycobacterial antigens and uses thereof
US20070105100A1 (en) * 2003-04-28 2007-05-10 Canon Kabushiki Kaisha Process for assay of nucleic acids by competitive hybridization using a dna microarray
ITRM20030411A1 (it) * 2003-08-29 2005-02-28 Consiglio Nazionale Ricerche Uso di sequenze geniche specifiche di mycobacterium tubercolosis ecorrispondenti proteine per la diagnosi e la prevenzione di infezione tubercolare.
US7608277B2 (en) * 2004-12-01 2009-10-27 Gene Therapy Systems, Inc. Tuberculosis nucleic acids, polypeptides and immunogenic compositions
WO2006117538A2 (en) * 2005-04-29 2006-11-09 Fusion Antibodies Limited Assays for diagnosis of tuberculosis and uses thereof
CA2616766A1 (en) 2005-07-26 2007-02-01 University Of Medicine And Dentistry Of New Jersey Antibody profiles characteristic of tuberculosis state
EP1922415B1 (de) * 2005-09-05 2013-12-25 Bio-Rad Innovations Verwendung von sowohl rd9 als auch is6110 als nukleinsäureziele für die diagnose von tuberkulose und bereitstellung multiplex-tauglicher is6110- und rd-9-ziele
EP2021018A4 (de) * 2006-05-18 2009-06-03 Daniel G Ericson Rascher nachweis von mykobakteriumtuberkulose und resistenz gegen antimikrobika
BRPI0604958B1 (pt) * 2006-11-23 2022-05-17 Fundação Oswaldo Cruz Kit para distinção de mycobacterium tuberculosis, m. bovis, m. bovis bcg em uma amostra, e, método para distinguir mycobacterium tuberculosis, m. bovis, m. bovis bcg
CN101661044B (zh) * 2008-08-27 2013-10-16 复旦大学附属华山医院 一种结核病诊断试剂及试剂盒
WO2010030049A1 (en) * 2008-09-12 2010-03-18 Lg Life Sciences, Ltd. Composition for detection of m. tuberculosis complex or mycobacteria genus and simultaneous detection method for m. tuberculosis complex and mycobacteria genus with multiplex real time pcr using the same
GB0903168D0 (en) 2009-02-25 2009-04-08 Fusion Antibodies Ltd Diagnostic method and kit
CN102713629B (zh) 2009-11-20 2016-02-24 俄勒冈健康科学大学 用于检测结核分枝杆菌感染的方法
KR101158647B1 (ko) * 2010-05-27 2012-06-26 울산대학교 산학협력단 이중 실시간 중합효소연쇄반응법과 융해곡선분석을 이용하는 결핵균과 항산성비결핵균의 검출 방법
US9663758B2 (en) 2013-03-12 2017-05-30 Wisconsin Alumni Research Foundation Global gene regulators (GGR) as vaccine candidates against paratuberculosis
CN110073215B (zh) * 2016-09-22 2024-04-30 佩斯诊断公司 结核分枝杆菌蛋白诊断测定和结核病检测和诊断装置
KR102247643B1 (ko) * 2019-11-01 2021-05-03 바이오파크진단 주식회사 결핵균 및 비결핵항산균을 검출하기 위한 2단계 진단방법 및 키트

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* Cited by examiner, † Cited by third party
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US5591632A (en) 1987-03-02 1997-01-07 Beth Israel Hospital Recombinant BCG
WO1988006626A1 (en) * 1987-03-02 1988-09-07 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
EP0499003A1 (de) * 1991-02-14 1992-08-19 N.V. Innogenetics S.A. Polypeptide und Peptide, insbesondere rekombinante Polypeptide und Peptide, dafür kodierende Nukleinsäuren und Verwendung dieser Polypeptide und Peptide in der Tuberkulosediagnose
DK79793D0 (da) * 1993-07-02 1993-07-02 Statens Seruminstitut Diagnostic test
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US5700683A (en) 1995-02-17 1997-12-23 Pathogenesis Corporation Virulence-attenuating genetic deletions deleted from mycobacterium BCG
AU4996796A (en) 1995-02-28 1996-09-18 Joel R.L. Ehrenkranz Rapid, self-performing tsh immunoassay
US5686597A (en) 1995-06-06 1997-11-11 Incyte Pharmaceuticals, Inc. Thrombin receptor homolog
CA2276491C (en) * 1996-12-31 2008-01-22 New York University Early detection of mycobacterial disease
US20040013685A1 (en) * 1997-11-10 2004-01-22 Peter Andersen Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
US6291190B1 (en) * 1998-08-25 2001-09-18 The Board Of Trustees Of The Leland Stanford Junior University Molecular differences between species of the M. tuberculosis complex
JP5010079B2 (ja) * 1999-07-13 2012-08-29 スタテンズ セーラム インスティテュート マイコバクテリウム・ツベルクローシスｅｓａｔ−６遺伝子ファミリーベースの結核ワクチン及び診断法

Also Published As

Publication number Publication date
PT2006395E (pt) 2011-07-13
US6686166B2 (en) 2004-02-03
ATE473299T1 (de) 2010-07-15
DE69943401D1 (de) 2011-06-09
EP2006395B1 (de) 2011-04-27
WO2000011214B1 (en) 2000-04-13
WO2000011214A1 (en) 2000-03-02
US20020176873A1 (en) 2002-11-28
ATE466100T1 (de) 2010-05-15
US20080254052A1 (en) 2008-10-16
ES2343927T3 (es) 2010-08-12
US20060002953A1 (en) 2006-01-05
DE69942310D1 (de) 2010-06-10
EP2006395A1 (de) 2008-12-24
AU5394699A (en) 2000-03-14
PT1108060E (pt) 2010-08-04
DK1108060T3 (da) 2010-08-16
DK2006395T3 (da) 2011-07-18
US7364740B2 (en) 2008-04-29
DK2031075T3 (da) 2010-10-18
EP2031075A1 (de) 2009-03-04
EP1108060B1 (de) 2010-04-28
US6291190B1 (en) 2001-09-18
US7700118B2 (en) 2010-04-20
US20040063923A1 (en) 2004-04-01
EP2031075B1 (de) 2010-07-07
US20110206715A1 (en) 2011-08-25
EP1108060A1 (de) 2001-06-20
DE69942569D1 (de) 2010-08-19

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