ATE513202T1 - Verfahren und vorrichtung zur dreidimensionalen rekonstruktion der verteilung von fluoreszierenden elementen - Google Patents

Verfahren und vorrichtung zur dreidimensionalen rekonstruktion der verteilung von fluoreszierenden elementen

Info

Publication number
ATE513202T1
ATE513202T1 AT07113448T AT07113448T ATE513202T1 AT E513202 T1 ATE513202 T1 AT E513202T1 AT 07113448 T AT07113448 T AT 07113448T AT 07113448 T AT07113448 T AT 07113448T AT E513202 T1 ATE513202 T1 AT E513202T1
Authority
AT
Austria
Prior art keywords
fluorescence signal
distribution
dimensional reconstruction
fluorophore
fluorescent elements
Prior art date
Application number
AT07113448T
Other languages
English (en)
Inventor
Aurelie Laidevant
Silva Anabela Da
Jean-Marc Dinten
Original Assignee
Commissariat Energie Atomique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat Energie Atomique filed Critical Commissariat Energie Atomique
Application granted granted Critical
Publication of ATE513202T1 publication Critical patent/ATE513202T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
AT07113448T 2006-08-02 2007-07-30 Verfahren und vorrichtung zur dreidimensionalen rekonstruktion der verteilung von fluoreszierenden elementen ATE513202T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0607065A FR2904691B1 (fr) 2006-08-02 2006-08-02 Procede et dispositif de reconstruction 3d de la distribution d'elements fluorescents.

Publications (1)

Publication Number Publication Date
ATE513202T1 true ATE513202T1 (de) 2011-07-15

Family

ID=37808329

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07113448T ATE513202T1 (de) 2006-08-02 2007-07-30 Verfahren und vorrichtung zur dreidimensionalen rekonstruktion der verteilung von fluoreszierenden elementen

Country Status (4)

Country Link
US (2) US7675044B2 (de)
EP (1) EP1884765B1 (de)
AT (1) ATE513202T1 (de)
FR (1) FR2904691B1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4259879B2 (ja) 2001-05-17 2009-04-30 ゼノジェン コーポレイション 身体領域内の標的の深さ、輝度およびサイズを決定するための方法および装置
FR2904691B1 (fr) * 2006-08-02 2009-03-06 Commissariat Energie Atomique Procede et dispositif de reconstruction 3d de la distribution d'elements fluorescents.
EP3501384B1 (de) 2008-05-20 2024-07-17 University Health Network Verfahren zur bildgebung und überwachung auf fluoreszenzbasis
FR2938181B1 (fr) 2008-11-13 2012-03-09 Commissariat Energie Atomique Procede et dispositif de localisation de fluorophores ou d'absorbeurs dans un milieu environnant
DE102009005953A1 (de) * 2009-01-19 2010-07-22 Universität Tübingen Verfahren und System zur Charakterisierung einer Probe mittels bildgebender Fluoreszenzmikroskopie
JP5283525B2 (ja) * 2009-01-30 2013-09-04 富士フイルム株式会社 光断層情報の生成方法、光断層情報生成装置及び光断層情報の生成プログラム
FR2950431B1 (fr) * 2009-09-24 2011-12-09 Commissariat Energie Atomique Dispositif et procede de reconstruction spatiale d'une cartographie de fluorescence
FR2951283B1 (fr) 2009-10-08 2013-02-15 Commissariat Energie Atomique Procede et dispositif pour l'excitation diffuse en imagerie
FR2968921B1 (fr) 2010-12-15 2013-01-11 Commissariat Energie Atomique Procede de localisation d'un marqueur optique dans un milieu diffusant
FR2984502B1 (fr) * 2011-12-16 2014-02-21 Commissariat Energie Atomique Procede de reconstruction des proprietes optiques d'un milieu avec calcul d'un signal corrige en fonction d'une premiere fonction de modelisation pour un milieu de reference et d'une deuxieme distribution pour un milieu a caracteriser, et systeme de reconstruction associe
FR2984503B1 (fr) * 2011-12-16 2014-01-17 Commissariat Energie Atomique Procede de reconstruction de proprietes optiques d'un milieu diffusant a l'aide d'une combinaison d'une pluralite de transformees de mellin-laplace d'une grandeur comportant une distribution temporelle d'un signal recu, et systeme de reconstruction associe
FR2985023B1 (fr) * 2011-12-23 2016-05-06 Commissariat Energie Atomique Systeme de reconstruction de proprietes optiques d'un milieu diffusant, comprenant une source de rayonnement pulsee et au moins deux detecteurs de deux types differents, et procede de reconstruction associe
DE102013213362A1 (de) * 2013-07-08 2015-01-08 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Identifizierung und Quantifizierung von emittierenden Teilchen in Systemen
FR3016461B1 (fr) * 2014-01-10 2017-06-23 Imabiotech Procede de traitement de donnees d'imagerie moleculaire et serveur de donnees correspondant
PL3171765T3 (pl) 2014-07-24 2022-01-03 University Health Network Zbieranie i analiza danych do celów diagnostycznych
CN104188628B (zh) * 2014-09-16 2017-02-22 中国科学院自动化研究所 三维光学分子影像导航系统
DE102019000066B4 (de) * 2019-01-09 2020-10-08 Becker & Hickl Gmbh Verfahren zur Visualisierung von Fluoreszenz-Lifetime-Imaging-Daten
CN113203487B (zh) * 2021-03-18 2022-07-19 深圳大学 一种荧光寿命偏差的定量化校正方法及装置
FR3131376B1 (fr) * 2021-12-29 2023-11-10 Commissariat Energie Atomique Procédé d’estimation d’une distribution spatiale tridimensionnelle de fluorescence, à l’intérieur d’un objet.

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US5919140A (en) * 1995-02-21 1999-07-06 Massachusetts Institute Of Technology Optical imaging using time gated scattered light
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US20060149479A1 (en) 2004-12-30 2006-07-06 Art, Advanced Research Technologies Inc. Method for improving fluorescence image contrast
FR2882147B1 (fr) 2005-02-14 2007-10-05 Commissariat Energie Atomique Dispositif d'imagerie de fluorescence par reflexion a deux longueurs d'onde
US20090164130A1 (en) 2005-06-10 2009-06-25 General Hospital Corporation Fluorescence-lifetime-based tomography
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FR2904691B1 (fr) * 2006-08-02 2009-03-06 Commissariat Energie Atomique Procede et dispositif de reconstruction 3d de la distribution d'elements fluorescents.
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Also Published As

Publication number Publication date
EP1884765B1 (de) 2011-06-15
FR2904691B1 (fr) 2009-03-06
FR2904691A1 (fr) 2008-02-08
US20100224797A1 (en) 2010-09-09
US7977650B2 (en) 2011-07-12
US7675044B2 (en) 2010-03-09
EP1884765A1 (de) 2008-02-06
US20080067420A1 (en) 2008-03-20

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