ATE514091T1 - Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit - Google Patents
Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheitInfo
- Publication number
- ATE514091T1 ATE514091T1 AT08786791T AT08786791T ATE514091T1 AT E514091 T1 ATE514091 T1 AT E514091T1 AT 08786791 T AT08786791 T AT 08786791T AT 08786791 T AT08786791 T AT 08786791T AT E514091 T1 ATE514091 T1 AT E514091T1
- Authority
- AT
- Austria
- Prior art keywords
- procalcitonin
- prognosis
- pct
- infectious disease
- patients
- Prior art date
Links
- 108010048233 Procalcitonin Proteins 0.000 title abstract 4
- CWCXERYKLSEGEZ-KDKHKZEGSA-N procalcitonin Chemical compound C([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)NCC(O)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCSC)NC(=O)[C@H]1NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)CNC(=O)[C@@H](N)CSSC1)[C@@H](C)O)[C@@H](C)O)[C@@H](C)O)C1=CC=CC=C1 CWCXERYKLSEGEZ-KDKHKZEGSA-N 0.000 title abstract 4
- 208000031662 Noncommunicable disease Diseases 0.000 title abstract 2
- 238000004393 prognosis Methods 0.000 title abstract 2
- 238000013517 stratification Methods 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/585—Calcitonins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07015271A EP2020603A1 (de) | 2007-08-03 | 2007-08-03 | Verfahren zur Einteilung von Risikoklassen bei stabiler Erkrankung der Koronaraterien |
| EP08152651A EP2101178A1 (de) | 2008-03-12 | 2008-03-12 | Verwendung von Procalcitonin zur Prognose folgender akuter Koronarsyndromen |
| PCT/EP2008/060176 WO2009019230A2 (en) | 2007-08-03 | 2008-08-01 | Use of procalcitonin (pct) in risk stratification and prognosis of patients with a primary, non-infectious disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE514091T1 true ATE514091T1 (de) | 2011-07-15 |
Family
ID=39745280
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10188288T ATE533061T1 (de) | 2007-08-03 | 2008-08-01 | Verfahren zur diagnose bakterieller infektionen |
| AT08786791T ATE514091T1 (de) | 2007-08-03 | 2008-08-01 | Verwendung von procalcitonin (pct) zur risikostratifikation und prognose bei patienten mit einer primären nichtinfektiösen krankheit |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10188288T ATE533061T1 (de) | 2007-08-03 | 2008-08-01 | Verfahren zur diagnose bakterieller infektionen |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20110136161A1 (de) |
| EP (4) | EP2293078B1 (de) |
| JP (2) | JP5059943B2 (de) |
| CN (3) | CN110346577A (de) |
| AT (2) | ATE533061T1 (de) |
| DE (1) | DE602008021800C5 (de) |
| ES (3) | ES2401703T3 (de) |
| WO (1) | WO2009019230A2 (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2293078B1 (de) | 2007-08-03 | 2011-11-09 | B.R.A.H.M.S GmbH | Verfahren zur Diagnose bakterieller Infektionen |
| PT2419741T (pt) * | 2009-04-14 | 2019-11-04 | Brahms Gmbh | Avaliação de risco para tratamento com antibióticos em pacientes que sofrem de doença não infeciosa primária através da determinação do nível de procalcitonina |
| JP5731489B2 (ja) * | 2009-06-05 | 2015-06-10 | ベー.エル.アー.ハー.エム.エス ゲゼルシャフト ミット ベシュレンクテル ハフツング | 呼吸困難を起こした患者における細菌感染の検出 |
| EP2470910B1 (de) | 2009-08-28 | 2017-01-11 | B.R.A.H.M.S GmbH | Procalcitonin zur Prognose von Nebenwirkungen |
| ES2601104T3 (es) | 2009-10-13 | 2017-02-14 | B.R.A.H.M.S Gmbh | Procalcitonina para el diagnóstico de infecciones bacterianas y la guía del tratamiento antibiótico en pacientes con apoplejía aguda o accidente isquémico transitorio |
| WO2011110565A1 (en) * | 2010-03-08 | 2011-09-15 | B.R.A.H.M.S Gmbh | Procalcitonin for the diagnosis of bacterial infections and guidance of antibiotic treatment in patients with non-specific complaints |
| ITRM20100121A1 (it) * | 2010-03-18 | 2011-09-19 | Univ Pisa | Marcatori molecolari per infezioni delle vie urinarie. |
| EP2583103B1 (de) * | 2010-06-18 | 2016-04-20 | B.R.A.H.M.S GmbH | Biomarker zur Vorhersage der Inzidenz von Krebs |
| US20130024205A1 (en) * | 2011-07-18 | 2013-01-24 | International Business Machines Corporation | Dynamically updating electronic medical records and leveraging a person's path in a facility to mitgate risks |
| CA2863819C (en) | 2012-02-09 | 2021-11-23 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections and methods of use thereof |
| IN2014MN02101A (de) * | 2012-04-12 | 2015-08-28 | Brahms Gmbh | |
| MX357740B (es) | 2012-05-18 | 2018-07-23 | Critical Care Diagnostics Inc | Métodos para determinar el pronóstico del tratamiento de un sujeto con un desfibrilador cardíaco implantado, un dispositivo de tratamiento de resincronización cardíaca o un dispositivo combinado de desfibrilador cardíaco implantado y de resincronización cardíaca. |
| CA2882133A1 (en) | 2012-08-16 | 2014-02-20 | Critical Care Diagnostics, Inc. | Methods for predicting risk of developing hypertension |
| IN2015DN04062A (de) | 2012-11-15 | 2015-10-09 | Ortho Clinical Diagnostics Inc | |
| CN111624346A (zh) | 2014-08-14 | 2020-09-04 | 米密德诊断学有限公司 | 用于预测及/或决定预后的套组 |
| US20170234873A1 (en) | 2014-10-14 | 2017-08-17 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections in non-human subjects and methods of use thereof |
| CA2968650A1 (en) | 2014-12-11 | 2016-06-16 | Memed Diagnostics Ltd. | Marker combinations for diagnosing infections and methods of use thereof |
| CA3012985A1 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
| US20180224464A1 (en) * | 2015-06-09 | 2018-08-09 | Osaka University | Method of predicting and determining therapeutic effect on rheumatoid arthritis due to biological formulation |
| WO2017149547A1 (en) | 2016-03-03 | 2017-09-08 | Memed Diagnostics Ltd. | Analyzing rna for diagnosing infection type |
| US11466331B2 (en) | 2016-03-03 | 2022-10-11 | Memed Diagnostics Ltd. | RNA determinants for distinguishing between bacterial and viral infections |
| CN106093416B (zh) * | 2016-05-18 | 2018-10-12 | 北京北方生物技术研究所有限公司 | 一种一步法检测降钙素原的试剂盒及其制备方法 |
| WO2018011796A1 (en) | 2016-07-10 | 2018-01-18 | Memed Diagnostics Ltd. | Early diagnosis of infections |
| CA3027341A1 (en) | 2016-07-10 | 2018-01-18 | Memed Diagnostics Ltd. | Protein signatures for distinguishing between bacterial and viral infections |
| EP3519834A4 (de) | 2016-09-29 | 2020-06-17 | MeMed Diagnostics Ltd. | Verfahren zur risikobewertung und krankheitsklassifizierung |
| EP3519833B1 (de) | 2016-09-29 | 2024-08-14 | MeMed Diagnostics Ltd. | Verfahren zur prognose und behandlung |
| CN111094981B (zh) * | 2017-09-13 | 2024-04-16 | B.R.A.H.M.S有限公司 | Pct和pro-adm作为监测抗生素治疗的标记物 |
| CN111656189A (zh) * | 2017-12-20 | 2020-09-11 | B.R.A.H.M.S有限公司 | 基于合并症患者的降钙素原的抗生素疗法指导 |
| US12322100B2 (en) | 2018-12-11 | 2025-06-03 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and grading of aortic stenosis severity |
| US11931207B2 (en) | 2018-12-11 | 2024-03-19 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device |
| US11446009B2 (en) | 2018-12-11 | 2022-09-20 | Eko.Ai Pte. Ltd. | Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images |
| US12001939B2 (en) | 2018-12-11 | 2024-06-04 | Eko.Ai Pte. Ltd. | Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views |
| US12400762B2 (en) | 2018-12-11 | 2025-08-26 | Eko.Ai Pte. Ltd. | Automatic clinical workflow that recognizes and analyzes 2D and doppler modality echocardiogram images for automated cardiac measurements and diagnosis of cardiac amyloidosis and hypertrophic cardiomyopathy |
| WO2022119593A1 (en) * | 2020-12-02 | 2022-06-09 | Beckman Coulter, Inc. | Detection of probability of developing sepsis |
| US20240221958A1 (en) | 2021-04-30 | 2024-07-04 | Roche Diagnostics Operations, Inc. | Pct marker panels for early detection of sepsis |
| JP2024516677A (ja) | 2021-04-30 | 2024-04-16 | エフ. ホフマン-ラ ロシュ アーゲー | 敗血症の早期検出用のngalマーカーパネル |
| WO2022229416A2 (en) | 2021-04-30 | 2022-11-03 | Roche Diagnostics Gmbh | Esm1 marker panels for early detection of sepsis |
| WO2022229440A2 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Sflt1 marker panels for early detection of sepsis |
| CN117242350A (zh) | 2021-04-30 | 2023-12-15 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的il6标志物组 |
| US20240230673A1 (en) | 2021-04-30 | 2024-07-11 | Roche Diagnostics Operations, Inc. | Gdf15 marker panels for early detection of sepsis |
| WO2022229421A2 (en) | 2021-04-30 | 2022-11-03 | F. Hoffmann-La Roche Ag | Strem1 marker panels for early detection of sepsis |
| JP2024516679A (ja) | 2021-04-30 | 2024-04-16 | エフ. ホフマン-ラ ロシュ アーゲー | 敗血症の早期検出用のigfbp7マーカーパネル |
| CN117321419A (zh) | 2021-04-30 | 2023-12-29 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的Presepsin标志物组 |
| JP2024537774A (ja) | 2021-09-29 | 2024-10-16 | エフ. ホフマン-ラ ロシュ アーゲー | 敗血症の早期検出のためのMR-proADMマーカーパネル |
| CN118742814A (zh) | 2022-02-21 | 2024-10-01 | 豪夫迈·罗氏有限公司 | 用于脓毒症的早期检测的dll1标志物组 |
| EP4357778A1 (de) | 2022-10-20 | 2024-04-24 | Heraeus Medical GmbH | Behandlung von mikrobiellen infektionen mit diagnose durch biomarker d-lactat |
| CN119306832B (zh) * | 2023-07-11 | 2025-08-08 | 东莞市朋志生物科技有限公司 | 抗降钙素原抗体、检测降钙素原的试剂和试剂盒 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4227454C1 (de) | 1992-08-19 | 1994-02-03 | Henning Berlin Gmbh | Verfahren zur Früherkennung, zur Erkennung des Schweregrads sowie zur therapiebegleitenden Verlaufsbeurteilung einer Sepsis sowie Mittel zur Durchführung des Verfahrens |
| US6147688A (en) | 1993-06-28 | 2000-11-14 | Athena Design Systems, Inc. | Method and apparatus for defining and selectively repeating unit image cells |
| US5795725A (en) | 1995-04-18 | 1998-08-18 | Biosite Diagnostics Incorporated | Methods for the assay of troponin I and T and selection of antibodies for use in immunoassays |
| DE19600875C1 (de) * | 1996-01-12 | 1997-06-26 | Brahms Diagnostica Gmbh | Diagnostisches Verfahren zur Bestimmung der Ätiologie entzündlicher Prozesse |
| US6156521A (en) | 1997-12-19 | 2000-12-05 | Biosite Diagnostics, Inc. | Methods for the recovery and measurement of troponin complexes |
| US5993811A (en) * | 1997-02-03 | 1999-11-30 | Biology Associates, Llc | Method and compositions for preventing and treating the systemic inflammatory response syndrome including sepsis |
| US5947124A (en) | 1997-03-11 | 1999-09-07 | Biosite Diagnostics Incorporated | Diagnostic for determining the time of a heart attack |
| DE19903336C2 (de) | 1999-01-28 | 2000-12-14 | Brahms Diagnostica Gmbh | Gebrauchsfertige Kalibratoren für die Bestimmung von Procalcitonin |
| US20040253637A1 (en) * | 2001-04-13 | 2004-12-16 | Biosite Incorporated | Markers for differential diagnosis and methods of use thereof |
| US7713705B2 (en) * | 2002-12-24 | 2010-05-11 | Biosite, Inc. | Markers for differential diagnosis and methods of use thereof |
| US7632647B2 (en) | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
| DE60233301D1 (de) * | 2001-05-04 | 2009-09-24 | Biosite Inc | Diagnostische marker für akute herzerkrankungen und verfahren des gebrauchs |
| AU2003302340B8 (en) | 2002-12-24 | 2008-09-11 | Biosite Incorporated | Markers for differential diagnosis and methods of use thereof |
| DE10316583A1 (de) * | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| EP1616181B1 (de) | 2003-04-17 | 2009-08-12 | Vermillion, Inc. | Mit natriuretischen peptiden verwandte polypeptide und verfahren zu ihrer identifizierung und verwendung |
| US20050148029A1 (en) | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
| WO2005035720A2 (en) * | 2003-10-03 | 2005-04-21 | Scantibodies Laboratory, Inc. | Methods and use of binding components for improving assay specificity |
| CA2485722A1 (en) | 2003-10-22 | 2005-04-22 | Paul Lehmann | Soluble transferrin receptor |
| EP1564558B1 (de) | 2004-02-13 | 2005-12-07 | B.R.A.H.M.S Aktiengesellschaft | Verfahren zur Bestimmung der Bildung von Endothelinen zu Zwecken der medizinischen Diagnostik, sowie Antikörper und Kits für die Durchführung eines solchen Verfahrens |
| US20060024744A1 (en) | 2004-07-28 | 2006-02-02 | Mills Rhonda A | Methods for substantially simultaneous evaluation of a sample containing a cellular target and a soluble analyte |
| DE102004041659A1 (de) | 2004-08-27 | 2006-03-02 | Institut Virion/Serion Gmbh | Testvorrichtung für die in vitro Diagnostik von Multianalyt-Tests und deren Verwendung |
| AU2006264175B2 (en) | 2005-06-28 | 2012-01-12 | Nowdiagnostics, Inc. | Membrane array and analytical device |
| DE102005034174A1 (de) * | 2005-07-21 | 2007-02-08 | B.R.A.H.M.S Ag | Liquordiagnostisches in vitro Verfahren zur Diagnose von Demenz-Erkrankungen und neuroinflammatorischen Erkrankungen |
| JP2009510478A (ja) * | 2005-10-03 | 2009-03-12 | バイオサイト インコーポレイテッド | 全身性炎症反応症候群の診断および/または予後診断のための方法および組成物 |
| CN1800384A (zh) * | 2005-11-08 | 2006-07-12 | 浙江大学 | 降钙素原的制备方法 |
| EP2005168A4 (de) | 2006-03-09 | 2009-05-20 | Biosite Inc | Verfahren und zusammensetzung zur diagnose von krankheiten der aorta |
| DE102006046996A1 (de) | 2006-10-01 | 2008-04-03 | Brahms Aktiengesellschaft | Diagnose von Infektionen oder Entzündungserkrankungen der Atemwege und Lunge assoziiert mit Herzinsuffizienz |
| EP2020603A1 (de) | 2007-08-03 | 2009-02-04 | BRAHMS Aktiengesellschaft | Verfahren zur Einteilung von Risikoklassen bei stabiler Erkrankung der Koronaraterien |
| EP2293078B1 (de) * | 2007-08-03 | 2011-11-09 | B.R.A.H.M.S GmbH | Verfahren zur Diagnose bakterieller Infektionen |
| DE102008037108A1 (de) | 2008-08-08 | 2010-02-11 | Samson Aktiengesellschaft | System zum Stellen eines Stellorgans |
| ES2601104T3 (es) * | 2009-10-13 | 2017-02-14 | B.R.A.H.M.S Gmbh | Procalcitonina para el diagnóstico de infecciones bacterianas y la guía del tratamiento antibiótico en pacientes con apoplejía aguda o accidente isquémico transitorio |
| US20110263438A1 (en) | 2010-04-22 | 2011-10-27 | Mehmet Ali Soylemez | Diagnosis and complication risk assessment of pancreatic diabetes using procalcitonin |
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2008
- 2008-08-01 EP EP10188288A patent/EP2293078B1/de active Active
- 2008-08-01 AT AT10188288T patent/ATE533061T1/de active
- 2008-08-01 US US12/671,702 patent/US20110136161A1/en not_active Abandoned
- 2008-08-01 JP JP2010518695A patent/JP5059943B2/ja active Active
- 2008-08-01 DE DE602008021800.7A patent/DE602008021800C5/de active Active
- 2008-08-01 ES ES10188289T patent/ES2401703T3/es active Active
- 2008-08-01 WO PCT/EP2008/060176 patent/WO2009019230A2/en not_active Ceased
- 2008-08-01 CN CN201910283751.1A patent/CN110346577A/zh active Pending
- 2008-08-01 CN CN201210451017.XA patent/CN103123359B/zh active Active
- 2008-08-01 ES ES10188288T patent/ES2377112T3/es active Active
- 2008-08-01 EP EP10188287A patent/EP2301626B1/de active Active
- 2008-08-01 ES ES10188287T patent/ES2403310T3/es active Active
- 2008-08-01 CN CN200880101846A patent/CN101790687A/zh active Pending
- 2008-08-01 EP EP10188289A patent/EP2293076B1/de active Active
- 2008-08-01 AT AT08786791T patent/ATE514091T1/de active
- 2008-08-01 EP EP08786791A patent/EP2174143B1/de active Active
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2011
- 2011-02-25 US US13/034,752 patent/US10456364B2/en active Active
-
2012
- 2012-08-02 JP JP2012171897A patent/JP5185460B2/ja active Active
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2019
- 2019-03-29 US US16/369,966 patent/US11241395B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2293076A2 (de) | 2011-03-09 |
| CN103123359A (zh) | 2013-05-29 |
| WO2009019230A3 (en) | 2009-04-23 |
| JP2012237760A (ja) | 2012-12-06 |
| CN103123359B (zh) | 2015-07-29 |
| US20110152170A1 (en) | 2011-06-23 |
| US20190224135A1 (en) | 2019-07-25 |
| JP5059943B2 (ja) | 2012-10-31 |
| US11241395B2 (en) | 2022-02-08 |
| WO2009019230A4 (en) | 2009-06-25 |
| EP2301626A3 (de) | 2011-11-16 |
| DE602008021800C5 (de) | 2022-05-05 |
| ES2403310T3 (es) | 2013-05-17 |
| CN110346577A (zh) | 2019-10-18 |
| EP2293076B1 (de) | 2012-12-19 |
| JP5185460B2 (ja) | 2013-04-17 |
| HK1183707A1 (en) | 2014-01-03 |
| JP2010536012A (ja) | 2010-11-25 |
| EP2293076A3 (de) | 2011-03-30 |
| EP2174143B1 (de) | 2011-06-22 |
| EP2293078B1 (de) | 2011-11-09 |
| US20110136161A1 (en) | 2011-06-09 |
| WO2009019230A2 (en) | 2009-02-12 |
| EP2301626B1 (de) | 2013-01-16 |
| ATE533061T1 (de) | 2011-11-15 |
| EP2293078A3 (de) | 2011-04-06 |
| ES2401703T3 (es) | 2013-04-23 |
| US10456364B2 (en) | 2019-10-29 |
| EP2174143A2 (de) | 2010-04-14 |
| ES2377112T3 (es) | 2012-03-22 |
| EP2301626A2 (de) | 2011-03-30 |
| CN101790687A (zh) | 2010-07-28 |
| EP2293078A2 (de) | 2011-03-09 |
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