ATE516297T1 - Mit copolymer 1 verwandte polypeptide zur verwendung als molekulargewichtsmarker und zur therapeutischen verwendung - Google Patents

Mit copolymer 1 verwandte polypeptide zur verwendung als molekulargewichtsmarker und zur therapeutischen verwendung

Info

Publication number: ATE516297T1
Authority: AT; Austria
Prior art keywords: molecular weight; weight markers; copolymer; copolymers; glatiramer acetate
Prior art date: 1998-09-25

Application number

AT09004306T

Other languages

English (en)

Inventor

Alexander Gad

Dora Lis

Original Assignee

Yeda Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-09-25

Filing date

1999-09-24

Publication date

2011-07-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22285926&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE516297(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-09-24 Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev

2011-07-15 Application granted granted Critical

2011-07-15 Publication of ATE516297T1 publication Critical patent/ATE516297T1/de

Links

229920001577 copolymer Polymers 0.000 title abstract 4
229920001184 polypeptide Polymers 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
108010072051 Glatiramer Acetate Proteins 0.000 abstract 3
FHEAIOHRHQGZPC-KIWGSFCNSA-N acetic acid;(2s)-2-amino-3-(4-hydroxyphenyl)propanoic acid;(2s)-2-aminopentanedioic acid;(2s)-2-aminopropanoic acid;(2s)-2,6-diaminohexanoic acid Chemical compound CC(O)=O.C[C@H](N)C(O)=O.NCCCC[C@H](N)C(O)=O.OC(=O)[C@@H](N)CCC(O)=O.OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 FHEAIOHRHQGZPC-KIWGSFCNSA-N 0.000 abstract 3
229960003776 glatiramer acetate Drugs 0.000 abstract 3
230000004071 biological effect Effects 0.000 abstract 1
208000026278 immune system disease Diseases 0.000 abstract 1
230000014759 maintenance of location Effects 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Immunology (AREA)
Diabetes (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Dermatology (AREA)
Biomedical Technology (AREA)
Orthopedic Medicine & Surgery (AREA)
Biochemistry (AREA)
Rheumatology (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Physical Education & Sports Medicine (AREA)
Neurosurgery (AREA)
Microbiology (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Emergency Medicine (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Pulmonology (AREA)

AT09004306T 1998-09-25 1999-09-24 Mit copolymer 1 verwandte polypeptide zur verwendung als molekulargewichtsmarker und zur therapeutischen verwendung ATE516297T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US10169398P	1998-09-25	1998-09-25

Publications (1)

Publication Number	Publication Date
ATE516297T1 true ATE516297T1 (de)	2011-07-15

Family

ID=22285926

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT09004306T ATE516297T1 (de)	1998-09-25	1999-09-24	Mit copolymer 1 verwandte polypeptide zur verwendung als molekulargewichtsmarker und zur therapeutischen verwendung
AT99949923T ATE431359T1 (de)	1998-09-25	1999-09-24	Copolymer-1-verwandte polypeptide für die verwendung als molekulargewichtsmarker und zur therapie

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT99949923T ATE431359T1 (de)	1998-09-25	1999-09-24	Copolymer-1-verwandte polypeptide für die verwendung als molekulargewichtsmarker und zur therapie

Country Status (17)

Country	Link
EP (3)	EP2239269B1 (de)
JP (2)	JP4629229B2 (de)
AT (2)	ATE516297T1 (de)
AU (1)	AU757413B2 (de)
CA (2)	CA2343929C (de)
CY (3)	CY1110490T1 (de)
DE (2)	DE69940888D1 (de)
DK (3)	DK2239269T3 (de)
ES (3)	ES2369642T3 (de)
HU (3)	HU229719B1 (de)
IL (4)	IL142116A0 (de)
NO (2)	NO329877B1 (de)
NZ (1)	NZ511020A (de)
PT (3)	PT2090583E (de)
SI (1)	SI1115743T1 (de)
WO (1)	WO2000018794A1 (de)
ZA (1)	ZA200102269B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2527760T3 (es)	1998-07-23	2015-01-29	Yeda Research And Development Co., Ltd.	Tratamiento de enfermedad de Crohn con copolímero 1 y polipéptidos
IL141021A0 (en)	1998-07-23	2002-02-10	Yeda Res & Dev	Treatment of autoimmune conditions with copolymer 1 and related copolymers
US6800287B2 (en)	1998-09-25	2004-10-05	Yeda Research And Development Co., Ltd.	Copolymer 1 related polypeptides for use as molecular weight markers and for therapeutic use
US7022663B2 (en)	2000-02-18	2006-04-04	Yeda Research And Development Co., Ltd.	Oral, nasal and pulmonary dosage formulations of copolymer 1
US20020077278A1 (en)	2000-06-05	2002-06-20	Yong V. Wee	Use of glatiramer acetate (copolymer 1) in the treatment of central nervous system disorders
AU6887101A (en) *	2000-06-20	2002-01-02	Caprion Pharmaceuticals, Inc.	Copolymers and methods of treating prion-related diseases
WO2002076503A1 (en)	2000-06-20	2002-10-03	Mayo Foundation For Medical Education And Research	Treatment of central nervous system diseases by antibodies against glatiramer acetate
US20040037828A1 (en) *	2002-07-09	2004-02-26	Bar-Ilan University	Methods and pharmaceutical compositions for healing wounds
DE02800437T1 (de)	2001-10-03	2004-11-11	The President And Fellows Of Harvard College, Cambridge	Copolymere zur unterdrückung von autoimmunkrankheiten und anwendungsverfahren
US7429374B2 (en)	2001-12-04	2008-09-30	Teva Pharmaceutical Industries, Ltd.	Process for the measurement of the potency of glatiramer acetate
RU2339397C2 (ru)	2003-01-21	2008-11-27	Йеда Рисерч Энд Дивелопмент Ко.Лтд.	Сор1 для лечения воспалительных заболеваний кишечника
WO2005013885A2 (en)	2003-08-07	2005-02-17	Healor Ltd.	Pharmaceutical compositions and methods for accelerating wound healing
AU2005219876A1 (en) *	2004-03-01	2005-09-15	Peptimmune, Inc.	Methods and compositions for treatment of autoimmune diseases
US7655221B2 (en)	2004-05-07	2010-02-02	Peptimmune, Inc.	Methods of treating disease with random copolymers
HRP20160455T1 (hr)	2004-09-09	2016-07-15	Yeda Research And Development Co., Ltd.	Smjese polipeptida, sastavi koji ih sadrže i postupci za njihovu pripremu, te njihove primjene
US7858337B2 (en)	2007-03-08	2010-12-28	Novartis Ag	Process for the manufacture of a composite material
NZ598661A (en)	2009-08-20	2013-02-22	Yeda Res & Dev	Low frequency glatiramer acetate therapy
USRE49251E1 (en)	2010-01-04	2022-10-18	Mapi Pharma Ltd.	Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en)	2010-03-16	2014-06-24	Teva Pharmaceutical Industries, Ltd.	Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
CA2814500A1 (en)	2010-10-11	2012-04-19	Teva Pharmaceutical Industries Ltd	Cytokine biomarkers as predictive biomarkers of clinical response for glatiramer acetate
CA2827275A1 (en)	2011-02-14	2012-09-20	Usv Limited	Copolymer-1, process for preparation and analytical methods thereof
HK1200274A1 (en)	2011-10-10	2015-08-07	Teva Pharmaceutical Industries Ltd.	Single nucleotide polymorphisms useful to predict clinical response for glatiramer acetate
HK1213830A1 (zh)	2012-10-10	2016-07-15	Teva Pharmaceutical Industries Ltd.	用於预测醋酸格拉替雷临床反应的生物标志物
CN104098655B (zh) *	2013-04-09	2018-01-30	深圳翰宇药业股份有限公司	用于合成醋酸格拉替雷的质谱内标的多肽
UY35790A (es)	2013-10-21	2015-05-29	Teva Pharma	Marcadores genéticos que predicen la respuesta al acetato de glatiramer
CN105218646B (zh) *	2014-06-24	2018-09-21	深圳翰宇药业股份有限公司	一种用于检测醋酸格拉替雷样本的uplc方法
US9155775B1 (en)	2015-01-28	2015-10-13	Teva Pharmaceutical Industries, Ltd.	Process for manufacturing glatiramer acetate product
CN112649538B (zh) *	2015-04-28	2024-03-29	深圳翰宇药业股份有限公司	多肽混合物高效液相色谱分析方法
EP3147667B1 (de) *	2015-09-24	2019-06-12	CHEMI S.p.A.	Analyse der molekulargewichtsverteilung von komplexen polypeptidmischungen
US12097292B2 (en)	2016-08-28	2024-09-24	Mapi Pharma Ltd.	Process for preparing microparticles containing glatiramer acetate
CN109982712A (zh)	2016-08-31	2019-07-05	Mapi医药公司	包含醋酸格拉替雷的储库系统
CN110382052A (zh)	2017-03-26	2019-10-25	Mapi医药公司	用于治疗进展型形式的多发性硬化症的格拉替雷储库系统

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CA2009996A1 (en) *	1989-02-17	1990-08-17	Kathleen S. Cook	Process for making genes encoding random polymers of amino acids
IL113812A (en)	1994-05-24	2000-06-29	Yeda Res & Dev	Copolymer-1 pharmaceutical compositions containing it and its use

1999
- 1999-09-24 DK DK10171553.0T patent/DK2239269T3/da active
- 1999-09-24 PT PT09004306T patent/PT2090583E/pt unknown
- 1999-09-24 PT PT101715530T patent/PT2239269E/pt unknown
- 1999-09-24 AT AT09004306T patent/ATE516297T1/de active
- 1999-09-24 EP EP10171553A patent/EP2239269B1/de not_active Expired - Lifetime
- 1999-09-24 EP EP99949923A patent/EP1115743B1/de not_active Expired - Lifetime
- 1999-09-24 AU AU62695/99A patent/AU757413B2/en not_active Expired
- 1999-09-24 HU HU1300505A patent/HU229719B1/hu unknown
- 1999-09-24 HU HU1300337A patent/HU229720B1/hu unknown
- 1999-09-24 HU HU0103889A patent/HU229289B1/hu unknown
- 1999-09-24 JP JP2000572252A patent/JP4629229B2/ja not_active Expired - Lifetime
- 1999-09-24 SI SI9931035T patent/SI1115743T1/sl unknown
- 1999-09-24 DE DE69940888T patent/DE69940888D1/de not_active Expired - Lifetime
- 1999-09-24 DK DK99949923T patent/DK1115743T3/da active
- 1999-09-24 CA CA2343929A patent/CA2343929C/en not_active Expired - Lifetime
- 1999-09-24 ES ES09004306T patent/ES2369642T3/es not_active Expired - Lifetime
- 1999-09-24 ZA ZA200102269A patent/ZA200102269B/en unknown
- 1999-09-24 IL IL14211699A patent/IL142116A0/xx unknown
- 1999-09-24 WO PCT/US1999/022402 patent/WO2000018794A1/en not_active Ceased
- 1999-09-24 NZ NZ511020A patent/NZ511020A/xx not_active IP Right Cessation
- 1999-09-24 EP EP09004306A patent/EP2090583B1/de not_active Expired - Lifetime
- 1999-09-24 AT AT99949923T patent/ATE431359T1/de active
- 1999-09-24 DE DE09004306T patent/DE09004306T1/de active Pending
- 1999-09-24 ES ES10171553T patent/ES2408706T3/es not_active Expired - Lifetime
- 1999-09-24 CA CA2794705A patent/CA2794705C/en not_active Expired - Lifetime
- 1999-09-24 ES ES99949923T patent/ES2327301T3/es not_active Expired - Lifetime
- 1999-09-24 DK DK09004306.8T patent/DK2090583T3/da active
- 1999-09-24 PT PT99949923T patent/PT1115743E/pt unknown
2001
- 2001-03-20 IL IL142116A patent/IL142116A/en not_active IP Right Cessation
- 2001-03-21 NO NO20011441A patent/NO329877B1/no not_active IP Right Cessation
2009
- 2009-08-06 CY CY20091100835T patent/CY1110490T1/el unknown
2010
- 2010-03-25 NO NO20100442A patent/NO336685B1/no not_active IP Right Cessation
- 2010-06-23 JP JP2010142689A patent/JP4903886B2/ja not_active Expired - Lifetime
- 2010-11-07 IL IL209189A patent/IL209189A/en not_active IP Right Cessation
- 2010-11-07 IL IL209190A patent/IL209190A/en not_active IP Right Cessation
2011
- 2011-10-05 CY CY20111100947T patent/CY1112197T1/el unknown
2013
- 2013-04-15 CY CY20131100310T patent/CY1113932T1/el unknown

Also Published As

Publication number	Publication date
PT2239269E (pt)	2013-04-09
EP2239269A1 (de)	2010-10-13
DK1115743T3 (da)	2009-07-27
HUP0103889A3 (en)	2004-03-01
IL142116A (en)	2010-12-30
CY1112197T1 (el)	2015-12-09
PT1115743E (pt)	2009-07-07
ZA200102269B (en)	2002-03-19
JP4903886B2 (ja)	2012-03-28
JP4629229B2 (ja)	2011-02-09
ATE431359T1 (de)	2009-05-15
DE69940888D1 (de)	2009-06-25
IL209189A0 (en)	2011-01-31
HU229719B1 (en)	2014-05-28
NO336685B1 (no)	2015-10-19
ES2408706T3 (es)	2013-06-21
IL142116A0 (en)	2002-03-10
EP2090583A1 (de)	2009-08-19
EP2090583B1 (de)	2011-07-13
IL209190A (en)	2017-11-30
EP1115743A1 (de)	2001-07-18
AU757413B2 (en)	2003-02-20
SI1115743T1 (sl)	2010-01-29
CA2794705A1 (en)	2000-04-06
IL209190A0 (en)	2011-01-31
HK1133021A1 (en)	2010-03-12
CY1110490T1 (el)	2015-04-29
DK2090583T3 (da)	2011-09-12
JP2002525378A (ja)	2002-08-13
EP1115743A4 (de)	2005-04-27
CY1113932T1 (el)	2016-07-27
HK1149279A1 (en)	2011-09-30
JP2010271325A (ja)	2010-12-02
PT2090583E (pt)	2011-09-14
ES2369642T3 (es)	2011-12-02
CA2794705C (en)	2017-07-18
HU229289B1 (en)	2013-10-28
NO20100442L (no)	2001-05-25
CA2343929C (en)	2013-01-29
EP2239269B1 (de)	2013-01-16
HU229720B1 (en)	2014-05-28
HUP0103889A2 (hu)	2002-03-28
DE09004306T1 (de)	2010-12-09
HK1040521A1 (en)	2002-06-14
NO329877B1 (no)	2011-01-17
IL209189A (en)	2017-11-30
NO20011441D0 (no)	2001-03-21
WO2000018794A1 (en)	2000-04-06
NO20011441L (no)	2001-05-25
EP1115743B1 (de)	2009-05-13
NZ511020A (en)	2003-06-30
DK2239269T3 (da)	2013-04-29
ES2327301T3 (es)	2009-10-27
AU6269599A (en)	2000-04-17
CA2343929A1 (en)	2000-04-06

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ATE516297T1 (de)	2011-07-15	Mit copolymer 1 verwandte polypeptide zur verwendung als molekulargewichtsmarker und zur therapeutischen verwendung
DK0737207T3 (da)	2005-01-31	Inhibitorer for humant plasmin afledt af Kunitz-domæner
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ATE226634T1 (de)	2002-11-15	Fibronektin bindendes protein
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