ATE517892T1 - Enantioselektive synthese pyrrolidinsubstituierter flavone - Google Patents

Enantioselektive synthese pyrrolidinsubstituierter flavone

Info

Publication number
ATE517892T1
ATE517892T1 AT06766035T AT06766035T ATE517892T1 AT E517892 T1 ATE517892 T1 AT E517892T1 AT 06766035 T AT06766035 T AT 06766035T AT 06766035 T AT06766035 T AT 06766035T AT E517892 T1 ATE517892 T1 AT E517892T1
Authority
AT
Austria
Prior art keywords
pyrrolidine
enantioselective synthesis
substituted flavones
flavones
substituted
Prior art date
Application number
AT06766035T
Other languages
English (en)
Inventor
Meenakshi Sivakumar
Manoj Shukla
Pramod Kumar Jadhav
Ajit Borhade
Original Assignee
Piramal Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Piramal Life Sciences Ltd filed Critical Piramal Life Sciences Ltd
Application granted granted Critical
Publication of ATE517892T1 publication Critical patent/ATE517892T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT06766035T 2006-07-07 2006-07-07 Enantioselektive synthese pyrrolidinsubstituierter flavone ATE517892T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2006/052294 WO2008007169A1 (en) 2006-07-07 2006-07-07 An enantioselective synthesis of pyrrolidine-substituted flavones

Publications (1)

Publication Number Publication Date
ATE517892T1 true ATE517892T1 (de) 2011-08-15

Family

ID=37546592

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06766035T ATE517892T1 (de) 2006-07-07 2006-07-07 Enantioselektive synthese pyrrolidinsubstituierter flavone

Country Status (17)

Country Link
US (1) US7951961B2 (de)
EP (1) EP2041121B1 (de)
JP (1) JP5006396B2 (de)
KR (1) KR101285957B1 (de)
CN (1) CN101484445B (de)
AR (1) AR061964A1 (de)
AT (1) ATE517892T1 (de)
AU (1) AU2006346193C1 (de)
BR (1) BRPI0621851A2 (de)
CA (1) CA2658215C (de)
DK (1) DK2041121T3 (de)
IL (1) IL196298A0 (de)
MX (1) MX2009000109A (de)
NZ (1) NZ573841A (de)
PT (1) PT2041121E (de)
TW (1) TWI391388B (de)
WO (1) WO2008007169A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7884127B2 (en) 2002-07-08 2011-02-08 Pirimal Life Sciences Ltd. Inhibitors of cyclin dependent kinases and their use
LV14179B (lv) * 2008-12-03 2010-08-20 Ivars Kalvins 2,2'-ciklopropilidēn-bis-oksazolīnu reģenerēšana
TWI461194B (zh) 2009-05-05 2014-11-21 Piramal Entpr Ltd 吡咯啶取代黃酮作為輻射致敏劑
WO2012069972A1 (en) 2010-11-19 2012-05-31 Piramal Life Sciences Limited A pharmaceutical combination for the treatment of breast cancer
KR101264012B1 (ko) * 2010-12-31 2013-05-13 주식회사 코리아나화장품 플라바논 화합물 및 그 제조방법, 이로부터 제조된 화장료 조성물
TW201242597A (en) 2011-03-14 2012-11-01 Piramal Life Sciences Ltd A synergistic pharmaceutical combination for the treatment of pancreatic cancer
AU2012274990A1 (en) 2011-06-24 2014-02-06 Piramal Enterprises Limited Compounds for the treatment of cancers associated with human papillomavirus
EP2802323B1 (de) 2012-01-13 2016-08-10 Piramal Enterprises Limited Pyrrolidine-substituierte flavonderivate zur prävention oder behandlung oraler mucositis
WO2014018741A1 (en) * 2012-07-27 2014-01-30 Emory University Heterocyclic flavone derivatives, compositions, and methods related thereto
JP5988305B2 (ja) * 2013-03-29 2016-09-07 国立大学法人山口大学 光学活性α−ブロモベンゾイル酢酸エステル類の製造方法
CN111053768B (zh) 2013-07-12 2023-12-12 皮拉马尔企业有限公司 用于治疗黑素瘤的药物组合
CN104725279B (zh) * 2015-02-12 2018-03-02 威海迪素制药有限公司 一种N‑Boc‑联苯丙氨酸衍生物的制备方法
PL3294743T3 (pl) * 2015-05-12 2020-03-31 Fmc Corporation Podstawione arylem związki bicykliczne jako środki chwastobójcze

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849733A (en) * 1996-05-10 1998-12-15 Bristol-Myers Squibb Co. 2-thio or 2-oxo flavopiridol analogs
EP1280789A1 (de) * 2000-05-03 2003-02-05 LG Life Sciences Ltd. Cdk-inhibitoren mit 3-hydroxychromen-4-on-struktur
US6784167B2 (en) * 2000-09-29 2004-08-31 Bayer Pharmaceuticals Corporation 17-beta-hydroxysteroid dehydrogenase-II inhibitors
TWI331034B (en) * 2002-07-08 2010-10-01 Piramal Life Sciences Ltd Inhibitors of cyclin-dependent kinases and their use
JP5498782B2 (ja) 2006-06-21 2014-05-21 ピラマル エンタープライジーズ リミテッド 増殖性疾患治療用のエナンチオマー的に純粋なフラボン誘導体の調製方法

Also Published As

Publication number Publication date
CN101484445B (zh) 2012-09-05
TWI391388B (zh) 2013-04-01
TW200815413A (en) 2008-04-01
AR061964A1 (es) 2008-08-10
JP5006396B2 (ja) 2012-08-22
AU2006346193A2 (en) 2009-02-12
EP2041121B1 (de) 2011-07-27
BRPI0621851A2 (pt) 2013-01-29
MX2009000109A (es) 2009-03-16
CA2658215C (en) 2013-08-27
NZ573841A (en) 2011-11-25
DK2041121T3 (da) 2011-11-14
JP2009542796A (ja) 2009-12-03
US20100113803A1 (en) 2010-05-06
AU2006346193A1 (en) 2008-01-17
EP2041121A1 (de) 2009-04-01
US7951961B2 (en) 2011-05-31
CA2658215A1 (en) 2008-01-17
CN101484445A (zh) 2009-07-15
PT2041121E (pt) 2011-09-12
AU2006346193C1 (en) 2014-02-20
IL196298A0 (en) 2009-09-22
KR20090033465A (ko) 2009-04-03
KR101285957B1 (ko) 2013-07-12
AU2006346193B2 (en) 2012-11-15
HK1126762A1 (en) 2009-09-11
WO2008007169A1 (en) 2008-01-17

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