ATE518960T1 - Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpression - Google Patents
Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpressionInfo
- Publication number
- ATE518960T1 ATE518960T1 AT04784464T AT04784464T ATE518960T1 AT E518960 T1 ATE518960 T1 AT E518960T1 AT 04784464 T AT04784464 T AT 04784464T AT 04784464 T AT04784464 T AT 04784464T AT E518960 T1 ATE518960 T1 AT E518960T1
- Authority
- AT
- Austria
- Prior art keywords
- gene expression
- zinc finger
- finger proteins
- regulate gene
- produced zinc
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 239000011701 zinc Substances 0.000 title 1
- 229910052725 zinc Inorganic materials 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50450203P | 2003-09-19 | 2003-09-19 | |
| PCT/US2004/030606 WO2005028630A2 (en) | 2003-09-19 | 2004-09-17 | Engineered zinc finger proteins for regulation of gene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518960T1 true ATE518960T1 (de) | 2011-08-15 |
Family
ID=34375508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04784464T ATE518960T1 (de) | 2003-09-19 | 2004-09-17 | Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpression |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7407776B2 (de) |
| EP (1) | EP1678315B1 (de) |
| AT (1) | ATE518960T1 (de) |
| AU (1) | AU2004274957B2 (de) |
| CA (1) | CA2539439C (de) |
| WO (1) | WO2005028630A2 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ533327A (en) * | 2001-12-04 | 2006-11-30 | Teva Pharma | Processes for the measurement of the potency of glatiramer acetate |
| JP5147692B2 (ja) * | 2005-07-13 | 2013-02-20 | ノボ ノルディスク ヘルス ケア アーゲー | 治療用タンパク質生成のための宿主細胞タンパク質ノックアウト細胞 |
| US9217026B2 (en) * | 2006-11-13 | 2015-12-22 | Sangamo Biosciences, Inc. | Method of inactivating a glucocorticoid receptor gene in an isolated cell |
| US9187758B2 (en) | 2006-12-14 | 2015-11-17 | Sangamo Biosciences, Inc. | Optimized non-canonical zinc finger proteins |
| JP5666903B2 (ja) | 2007-05-23 | 2015-02-12 | サンガモ バイオサイエンシーズ， インコーポレイテッド | 導入遺伝子の発現を増強するための方法および組成物 |
| RU2712833C2 (ru) | 2009-10-22 | 2020-01-31 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Конструируемые белки с цинковыми пальцами, направленные на гены растений, вовлеченные в биосинтез жирных кислот |
| KR101974036B1 (ko) * | 2010-05-03 | 2019-04-30 | 상가모 테라퓨틱스, 인코포레이티드 | 아연 핑거 모듈을 연결하기 위한 조성물 |
| JP6309461B2 (ja) | 2012-02-28 | 2018-04-11 | シグマ−アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニーＳｉｇｍａ−Ａｌｄｒｉｃｈ Ｃｏ．， ＬＬＣ | ヒストンアセチル化の標的化 |
| EP3597741A1 (de) | 2012-04-27 | 2020-01-22 | Duke University | Genetische korrektur mutierter gene |
| UA118090C2 (uk) * | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
| EP2958992A1 (de) | 2013-02-22 | 2015-12-30 | Cellular Dynamics International, Inc. | Hepatozytenproduktion über vorwärtsprogrammierung durch kombination aus gentechnik und chemotechnik |
| US9828582B2 (en) | 2013-03-19 | 2017-11-28 | Duke University | Compositions and methods for the induction and tuning of gene expression |
| WO2015164228A1 (en) | 2014-04-21 | 2015-10-29 | Cellular Dynamics International, Inc. | Hepatocyte production via forward programming by combined genetic and chemical engineering |
| GB201418965D0 (de) | 2014-10-24 | 2014-12-10 | Ospedale San Raffaele And Fond Telethon | |
| JP6929791B2 (ja) | 2015-02-09 | 2021-09-01 | デューク ユニバーシティ | エピゲノム編集のための組成物および方法 |
| US11970710B2 (en) | 2015-10-13 | 2024-04-30 | Duke University | Genome engineering with Type I CRISPR systems in eukaryotic cells |
| KR102787119B1 (ko) | 2015-11-30 | 2025-03-27 | 듀크 유니버시티 | 유전자 편집에 의한 인간 디스트로핀 유전자의 교정을 위한 치료용 표적 및 사용 방법 |
| US20190127713A1 (en) | 2016-04-13 | 2019-05-02 | Duke University | Crispr/cas9-based repressors for silencing gene targets in vivo and methods of use |
| EP4275747A3 (de) | 2016-07-19 | 2024-01-24 | Duke University | Therapeutische anwendungen von cpf1-basierter genomeditierung |
| US12509492B2 (en) | 2018-01-19 | 2025-12-30 | Duke University | Genome engineering with CRISPR-Cas systems in eukaryotes |
| EP3775214A2 (de) | 2018-03-30 | 2021-02-17 | University of Geneva | Mikrorna-expressionskonstrukte und deren verwendungen |
| CN110791523B (zh) * | 2019-12-13 | 2022-05-10 | 南京农业大学 | 一种棉花抗旱相关基因GhRCHY1及其应用 |
| CN115715295A (zh) | 2020-05-27 | 2023-02-24 | 安逊生物科学股份有限公司 | 将car t细胞重新定向到感兴趣的抗原的衔接分子 |
| GB202010075D0 (en) * | 2020-07-01 | 2020-08-12 | Imp College Innovations Ltd | Therapeutic nucleic acids, peptides and uses |
| EP4288550A4 (de) * | 2021-02-04 | 2024-12-25 | New York University | Nahtlose integration von manipulierten zinkfingern in endogene transkriptionsfaktoren zur steuerung ihrer natürlichen funktionen |
| JP2024534523A (ja) | 2021-09-21 | 2024-09-20 | スクライブ・セラピューティクス・インコーポレイテッド | 操作されたｃａｓｘリプレッサー系 |
| EP4448745A4 (de) * | 2021-12-15 | 2025-12-24 | Univ Indiana Trustees | Auf zellen abzielende zusammensetzungen und verfahren |
| EP4314267A1 (de) | 2022-06-07 | 2024-02-07 | Scribe Therapeutics Inc. | Zusammensetzungen und verfahren zum targeting von pcsk9 |
| EP4544051A2 (de) | 2022-06-24 | 2025-04-30 | Tune Therapeutics, Inc. | Zusammensetzungen, systeme und verfahren zur reduzierung von lipoprotein mit geringer dichte durch gezielte genunterdrückung |
| EP4573200A2 (de) | 2022-08-19 | 2025-06-25 | Tune Therapeutics, Inc. | Zusammensetzungen, systeme und verfahren zur regulierung des hepatitis-b-virus durch gezielte genunterdrückung |
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| ES2808687T3 (es) | 2003-08-08 | 2021-03-01 | Sangamo Therapeutics Inc | Métodos y composiciones para escisión dirigida y recombinación |
| KR100857125B1 (ko) | 2004-05-25 | 2008-09-11 | 주식회사 툴젠 | 단일클론 항체 생산을 증가시키는 폴리펩타이드, 이를코드하는 핵산 및 이의 용도 |
-
2004
- 2004-09-17 CA CA2539439A patent/CA2539439C/en not_active Expired - Lifetime
- 2004-09-17 AU AU2004274957A patent/AU2004274957B2/en not_active Expired
- 2004-09-17 WO PCT/US2004/030606 patent/WO2005028630A2/en not_active Ceased
- 2004-09-17 US US10/572,886 patent/US7407776B2/en not_active Expired - Lifetime
- 2004-09-17 EP EP04784464A patent/EP1678315B1/de not_active Expired - Lifetime
- 2004-09-17 AT AT04784464T patent/ATE518960T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2539439C (en) | 2012-10-23 |
| WO2005028630A2 (en) | 2005-03-31 |
| CA2539439A1 (en) | 2005-03-31 |
| WO2005028630A3 (en) | 2005-06-09 |
| EP1678315A2 (de) | 2006-07-12 |
| US20070059795A1 (en) | 2007-03-15 |
| EP1678315B1 (de) | 2011-08-03 |
| US7407776B2 (en) | 2008-08-05 |
| EP1678315A4 (de) | 2006-11-08 |
| AU2004274957B2 (en) | 2009-02-05 |
| AU2004274957A1 (en) | 2005-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |