ATE518960T1 - Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpression - Google Patents
Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpressionInfo
- Publication number
- ATE518960T1 ATE518960T1 AT04784464T AT04784464T ATE518960T1 AT E518960 T1 ATE518960 T1 AT E518960T1 AT 04784464 T AT04784464 T AT 04784464T AT 04784464 T AT04784464 T AT 04784464T AT E518960 T1 ATE518960 T1 AT E518960T1
- Authority
- AT
- Austria
- Prior art keywords
- gene expression
- zinc finger
- finger proteins
- regulate gene
- produced zinc
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 239000011701 zinc Substances 0.000 title 1
- 229910052725 zinc Inorganic materials 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50450203P | 2003-09-19 | 2003-09-19 | |
| PCT/US2004/030606 WO2005028630A2 (en) | 2003-09-19 | 2004-09-17 | Engineered zinc finger proteins for regulation of gene expression |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE518960T1 true ATE518960T1 (de) | 2011-08-15 |
Family
ID=34375508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04784464T ATE518960T1 (de) | 2003-09-19 | 2004-09-17 | Gentechnisch hergestellte zinkfingerproteine zur regulation der genexpression |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7407776B2 (de) |
| EP (1) | EP1678315B1 (de) |
| AT (1) | ATE518960T1 (de) |
| AU (1) | AU2004274957B2 (de) |
| CA (1) | CA2539439C (de) |
| WO (1) | WO2005028630A2 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2469393C (en) * | 2001-12-04 | 2010-05-25 | Teva Pharmaceutical Industries, Ltd. | Processes for the measurement of the potency of glatiramer acetate |
| US20080311095A1 (en) * | 2007-05-23 | 2008-12-18 | Sangamo Biosciences, Inc. | Methods and compositions for increased transgene expression |
| US7696318B2 (en) | 2005-07-13 | 2010-04-13 | Novo Nordisk Health Care Ag | Host cell protein knock-out cells for production of therapeutic proteins |
| WO2008060510A2 (en) | 2006-11-13 | 2008-05-22 | Sangamo Biosciences, Inc. | Zinc finger nuclease for targeting the human glucocorticoid receptor locus |
| ES2586210T3 (es) * | 2006-12-14 | 2016-10-13 | Sangamo Biosciences, Inc. | Proteínas de dedo de zinc no canónicas optimizadas |
| KR101813981B1 (ko) | 2009-10-22 | 2018-01-04 | 다우 아그로사이언시즈 엘엘씨 | 지방산 생합성에 포함된 식물 유전자를 표적하는 조작된 징크 핑거 단백질 |
| PL2566972T3 (pl) * | 2010-05-03 | 2020-06-29 | Sangamo Therapeutics, Inc. | Kompozycje do wiązania modułów z motywem palca cynkowego |
| JP6309461B2 (ja) | 2012-02-28 | 2018-04-11 | シグマ−アルドリッチ・カンパニー・リミテッド・ライアビリティ・カンパニーＳｉｇｍａ−Ａｌｄｒｉｃｈ Ｃｏ．， ＬＬＣ | ヒストンアセチル化の標的化 |
| WO2013163628A2 (en) | 2012-04-27 | 2013-10-31 | Duke University | Genetic correction of mutated genes |
| UA118090C2 (uk) * | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
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| US9828582B2 (en) | 2013-03-19 | 2017-11-28 | Duke University | Compositions and methods for the induction and tuning of gene expression |
| WO2015164228A1 (en) | 2014-04-21 | 2015-10-29 | Cellular Dynamics International, Inc. | Hepatocyte production via forward programming by combined genetic and chemical engineering |
| GB201418965D0 (de) | 2014-10-24 | 2014-12-10 | Ospedale San Raffaele And Fond Telethon | |
| JP6929791B2 (ja) | 2015-02-09 | 2021-09-01 | デューク ユニバーシティ | エピゲノム編集のための組成物および方法 |
| EP4089175A1 (de) | 2015-10-13 | 2022-11-16 | Duke University | Genom-engineering mit typ-i-crispr-systemen in eukaryotischen zellen |
| WO2017095967A2 (en) | 2015-11-30 | 2017-06-08 | Duke University | Therapeutic targets for the correction of the human dystrophin gene by gene editing and methods of use |
| EP3443081A4 (de) | 2016-04-13 | 2019-10-30 | Duke University | Crispr/cas9-basierte repressoren zur in-vivo-ausschaltung von gen-targets und verfahren zur verwendung |
| EP4275747A3 (de) | 2016-07-19 | 2024-01-24 | Duke University | Therapeutische anwendungen von cpf1-basierter genomeditierung |
| US12509492B2 (en) | 2018-01-19 | 2025-12-30 | Duke University | Genome engineering with CRISPR-Cas systems in eukaryotes |
| WO2019186274A2 (en) | 2018-03-30 | 2019-10-03 | University Of Geneva | Micro rna expression constructs and uses thereof |
| CN110791523B (zh) * | 2019-12-13 | 2022-05-10 | 南京农业大学 | 一种棉花抗旱相关基因GhRCHY1及其应用 |
| IL298558A (en) | 2020-05-27 | 2023-01-01 | Antion Biosciences Sa | Adapter molecules redirect CAR T cells to the antigen of interest |
| GB202010075D0 (en) * | 2020-07-01 | 2020-08-12 | Imp College Innovations Ltd | Therapeutic nucleic acids, peptides and uses |
| KR20230147644A (ko) * | 2021-02-04 | 2023-10-23 | 뉴욕 유니버시티 | 천연 기능을 징발하기 위한 내인성 전사 인자에 조작된 징크 핑거의 원활한 통합 |
| KR20240095525A (ko) | 2021-09-21 | 2024-06-25 | 스크라이브 테라퓨틱스 인크. | 조작된 casx 억제 시스템 |
| US20250051406A1 (en) * | 2021-12-15 | 2025-02-13 | The Trustees Of Indiana University | Cell targeting compositions and methods |
| GB2634837A (en) | 2022-06-07 | 2025-04-23 | Scribe Therapeutics Inc | Compositions and methods for the targeting of PCSK9 |
| KR20250044484A (ko) | 2022-06-24 | 2025-03-31 | 튠 쎄라퓨틱스, 인코포레이티드 | 표적 유전자 억제를 통해 저밀도 지단백질을 감소시키기 위한 조성물, 시스템, 및 방법 |
| CN120435557A (zh) | 2022-08-19 | 2025-08-05 | 图恩疗法股份有限公司 | 通过靶向基因阻遏调节乙型肝炎病毒的组合物、系统和方法 |
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-
2004
- 2004-09-17 US US10/572,886 patent/US7407776B2/en not_active Expired - Lifetime
- 2004-09-17 EP EP04784464A patent/EP1678315B1/de not_active Expired - Lifetime
- 2004-09-17 AU AU2004274957A patent/AU2004274957B2/en not_active Expired
- 2004-09-17 AT AT04784464T patent/ATE518960T1/de not_active IP Right Cessation
- 2004-09-17 CA CA2539439A patent/CA2539439C/en not_active Expired - Lifetime
- 2004-09-17 WO PCT/US2004/030606 patent/WO2005028630A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1678315A4 (de) | 2006-11-08 |
| US20070059795A1 (en) | 2007-03-15 |
| AU2004274957B2 (en) | 2009-02-05 |
| EP1678315B1 (de) | 2011-08-03 |
| US7407776B2 (en) | 2008-08-05 |
| WO2005028630A3 (en) | 2005-06-09 |
| CA2539439C (en) | 2012-10-23 |
| EP1678315A2 (de) | 2006-07-12 |
| WO2005028630A2 (en) | 2005-03-31 |
| AU2004274957A1 (en) | 2005-03-31 |
| CA2539439A1 (en) | 2005-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |