ATE522812T1 - Verfahren und zusammensetzung zum bestimmen von homocystein - Google Patents
Verfahren und zusammensetzung zum bestimmen von homocysteinInfo
- Publication number
- ATE522812T1 ATE522812T1 AT04777969T AT04777969T ATE522812T1 AT E522812 T1 ATE522812 T1 AT E522812T1 AT 04777969 T AT04777969 T AT 04777969T AT 04777969 T AT04777969 T AT 04777969T AT E522812 T1 ATE522812 T1 AT E522812T1
- Authority
- AT
- Austria
- Prior art keywords
- hcy
- determining
- homocysteine
- substrate
- conversion product
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
- G01N33/6815—Assays for specific amino acids containing sulfur, e.g. cysteine, cystine, methionine, homocysteine
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48686503P | 2003-07-10 | 2003-07-10 | |
| US10/801,623 US7097968B2 (en) | 2003-07-10 | 2004-03-15 | Methods and compositions for assaying homocysteine |
| PCT/US2004/022218 WO2005008252A2 (en) | 2003-07-10 | 2004-07-09 | Methods and compositions for assaying homocysteine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE522812T1 true ATE522812T1 (de) | 2011-09-15 |
Family
ID=33567973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04777969T ATE522812T1 (de) | 2003-07-10 | 2004-07-09 | Verfahren und zusammensetzung zum bestimmen von homocystein |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7097968B2 (de) |
| EP (2) | EP2306201B1 (de) |
| JP (1) | JP4686454B2 (de) |
| CN (2) | CN101900735B (de) |
| AT (1) | ATE522812T1 (de) |
| WO (1) | WO2005008252A2 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060160896A1 (en) * | 2002-02-04 | 2006-07-20 | Jallal Messadek | Therapeutic treatment |
| BE1015608A6 (fr) * | 2003-07-15 | 2005-06-07 | Messadek Jallal | Traitement des arterites. |
| WO2004091601A1 (fr) * | 2003-04-17 | 2004-10-28 | Jallal Messadek | Formulations orales flottantes pour la liberation controlee de la betaine |
| US8476034B2 (en) * | 2003-07-10 | 2013-07-02 | General Atomics | Methods and compositions for assaying homocysteine |
| BE1016128A6 (fr) * | 2004-07-22 | 2006-03-07 | Messadek Jallal | Combinaisons therapeutiques |
| WO2006050581A2 (en) * | 2004-11-10 | 2006-05-18 | Jallal Messadek | Betaine as agent against arthropod - or mosquito -borne diseases |
| BRPI0610249A2 (pt) * | 2005-04-27 | 2010-06-08 | Jallal Messadek | associação ou combinação farmacêutica, composição farmacêutica, processo de co-cristalização e o uso de insulina ou análogo de insulina |
| US8549412B2 (en) | 2007-07-25 | 2013-10-01 | Yahoo! Inc. | Method and system for display of information in a communication system gathered from external sources |
| WO2009065193A1 (en) * | 2007-11-21 | 2009-05-28 | Jallal Messadek | Treatment of aspirin resistance with betaine and/or betaine enriched molasses |
| US20090209754A1 (en) * | 2008-01-03 | 2009-08-20 | Macdonald Peter Lindsay | Process for the preparation of capecitabine |
| US8344115B2 (en) * | 2008-04-21 | 2013-01-01 | Chan-Sui Pang, legal representative | Immunoassay for specific determination of S-adenosylmethionine and analogs thereof in biological samples |
| JP6056138B2 (ja) * | 2010-12-28 | 2017-01-11 | 東ソー株式会社 | 免疫学的測定方法 |
| JP5919914B2 (ja) * | 2012-03-15 | 2016-05-18 | 東ソー株式会社 | ホモシステイン測定用前処理試薬 |
| CN104046682B (zh) * | 2013-03-13 | 2015-12-09 | 苏州博泰安生物科技有限公司 | 同型半胱氨酸的检测方法及其诊断试剂盒 |
| WO2014144851A1 (en) * | 2013-03-15 | 2014-09-18 | Huawei Technologies Co., Ltd. | Synchronizing and collaboration of information among a mobile device group |
| CN103901211B (zh) * | 2014-03-13 | 2015-07-29 | 复旦大学 | 一种dl-高半胱氨酸可视识别的新方法 |
| CN104111338B (zh) * | 2014-05-07 | 2016-03-02 | 山东博科生物产业有限公司 | 一种抗干扰性强的同型半胱氨酸检测试剂盒 |
| CN104111337B (zh) * | 2014-05-07 | 2016-01-06 | 山东博科生物产业有限公司 | 抗干扰性强的同型半胱氨酸检测试剂盒 |
| CN104531834A (zh) * | 2014-05-09 | 2015-04-22 | 山东博科生物产业有限公司 | 一种稳定的同型半胱氨酸检测试剂 |
| CN103952461A (zh) * | 2014-05-14 | 2014-07-30 | 山东博科生物产业有限公司 | 一种重复性好的同型半胱氨酸检测试剂盒 |
| CN104140996B (zh) * | 2014-08-04 | 2016-06-01 | 宁波美康生物科技股份有限公司 | 液体稳定酶法同型半胱氨酸试剂盒 |
| CN104630324B (zh) * | 2015-02-28 | 2016-11-09 | 北京爱必信生物技术有限公司 | 改进的同型半胱氨酸检测试剂及方法 |
| AU2016267091B2 (en) * | 2015-05-25 | 2020-01-16 | Xiujuan Hao | Use of fluorescence for the quick and easy determination of S-Adenosylmethionine, S-Adenosylhomocysteine and Homocysteine |
| CN104990973B (zh) * | 2015-07-06 | 2017-12-15 | 济南大学 | 一种固载甲基转移酶电极传感器的制备及应用 |
| CN106353291A (zh) * | 2016-09-29 | 2017-01-25 | 浙江达美生物技术有限公司 | 同型半胱氨酸的测定试剂及其制备方法 |
| CN106501201B (zh) * | 2016-12-31 | 2018-06-19 | 湖南永和阳光生物科技股份有限公司 | 一种用于检测同型半胱氨酸的酶循环方法 |
| CN110346575A (zh) * | 2018-04-04 | 2019-10-18 | 南京东纳生物科技有限公司 | 一种同型半胱氨酸荧光免疫层析检测试剂盒及其检测方法 |
| CN116148476A (zh) * | 2021-11-22 | 2023-05-23 | 首都师范大学 | 一种检测血清中甲基化半胱氨酸的方法 |
| CN116840197A (zh) * | 2022-03-23 | 2023-10-03 | 中国科学院苏州生物医学工程技术研究所 | 一种2’-o-甲基转移酶活性检测方法、试剂盒及应用 |
| CN118818052B (zh) * | 2023-04-21 | 2026-01-16 | 首都师范大学 | 一种检测甲基化半胱氨酸总量的方法和试剂盒 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| JPS5811857A (ja) * | 1981-07-15 | 1983-01-22 | Yamasa Shoyu Co Ltd | アデノシンの定量法 |
| JPS6030679A (ja) * | 1983-07-29 | 1985-02-16 | Nippon Zeon Co Ltd | Ｓ−アデノシル−ｌ−ホモシステインハイドロラ−ゼの製造法 |
| JPS60241884A (ja) * | 1984-05-15 | 1985-11-30 | Tokyo Daigaku | 自動サイクリング反応装置およびこれを用いる自動分析装置 |
| US4940658A (en) * | 1986-11-20 | 1990-07-10 | University Patents, Inc. | Assay for sulfhydryl amino acids and methods for detecting and distinguishing cobalamin and folic acid deficency |
| JP3034969B2 (ja) * | 1991-03-01 | 2000-04-17 | 旭化成工業株式会社 | アンモニア、α−アミノ酸類またはα−ケト酸の高感度定量法および高感度定量用組成物 |
| WO1993015220A1 (en) * | 1992-01-22 | 1993-08-05 | Axis Biochemicals As | Homocysteine assay |
| US6063581A (en) | 1992-01-22 | 2000-05-16 | Axis-Shield Asa | Immunoassay for homocysteine |
| US5861294A (en) | 1995-06-07 | 1999-01-19 | Abbott Laboratories | Adenosine kinase polypeptides |
| US5854023A (en) | 1997-07-17 | 1998-12-29 | Incyte Pharmaceuticals, Inc. | Polynucleotides encoding human S-adenosyl-5-homocysteine hydrolase derived from bladder |
| US5985540A (en) | 1997-07-24 | 1999-11-16 | Anticancer, Inc. | High specificity homocysteine assays for biological samples |
| US5885767A (en) | 1998-05-22 | 1999-03-23 | Biocatalytics, Inc. | Methods and compositions for quantitating L-homocysteine and/or l-methionine in a solution |
| US6174696B1 (en) | 1999-11-12 | 2001-01-16 | Genzyme Corporation | Method for the determination of homocysteine |
| GB9900159D0 (en) | 1999-01-05 | 1999-02-24 | Axis Biochemicals Asa | Assay |
| US6046017A (en) | 1999-06-14 | 2000-04-04 | Virginia Commonwealth University | Rapid and sensitive assay for homocysteine |
| WO2001002600A2 (en) | 1999-07-06 | 2001-01-11 | General Atomics | Detection of analytes using attenuated enzymes |
| US6376210B1 (en) | 1999-07-06 | 2002-04-23 | General Atomics | Methods and compositions for assaying analytes |
| US7192729B2 (en) | 1999-07-06 | 2007-03-20 | General Atomics | Methods for assaying homocysteine |
| US6664073B1 (en) | 1999-11-02 | 2003-12-16 | Catch Inc. | Enzymatic cycling assays for homocysteine and cystathionine |
| US6635438B2 (en) * | 1999-11-02 | 2003-10-21 | Catch, Inc. | Enzymatic cycling assays for homocysteine and cystathionine |
| US6610504B1 (en) * | 2000-04-10 | 2003-08-26 | General Atomics | Methods of determining SAM-dependent methyltransferase activity using a mutant SAH hydrolase |
| DE60136665D1 (de) * | 2000-06-30 | 2009-01-02 | Alfresa Pharma Corp | Verfahren zur Erkennung eines ganzen Homocysteins |
| US6867012B2 (en) | 2000-12-05 | 2005-03-15 | Toyo Boseki Kabushiki Kaisha | Determination method of biological component and reagent kit used therefor |
| CN100554948C (zh) | 2004-03-08 | 2009-10-28 | 王学忠 | 同型半胱氨酸测定方法及其试剂 |
-
2004
- 2004-03-15 US US10/801,623 patent/US7097968B2/en not_active Expired - Lifetime
- 2004-07-09 AT AT04777969T patent/ATE522812T1/de not_active IP Right Cessation
- 2004-07-09 CN CN201010134298.7A patent/CN101900735B/zh not_active Expired - Lifetime
- 2004-07-09 EP EP10181606.4A patent/EP2306201B1/de not_active Expired - Lifetime
- 2004-07-09 WO PCT/US2004/022218 patent/WO2005008252A2/en not_active Ceased
- 2004-07-09 EP EP04777969A patent/EP1644741B1/de not_active Expired - Lifetime
- 2004-07-09 CN CN2004800260094A patent/CN1849513B/zh not_active Expired - Lifetime
- 2004-07-09 JP JP2006518957A patent/JP4686454B2/ja not_active Expired - Fee Related
-
2006
- 2006-03-31 US US11/394,457 patent/US20060172362A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2306201B1 (de) | 2014-10-08 |
| CN101900735A (zh) | 2010-12-01 |
| US20060172362A1 (en) | 2006-08-03 |
| US7097968B2 (en) | 2006-08-29 |
| WO2005008252A2 (en) | 2005-01-27 |
| EP1644741A2 (de) | 2006-04-12 |
| JP2007528714A (ja) | 2007-10-18 |
| WO2005008252A3 (en) | 2005-02-24 |
| EP2306201A1 (de) | 2011-04-06 |
| JP4686454B2 (ja) | 2011-05-25 |
| US20050009128A1 (en) | 2005-01-13 |
| CN101900735B (zh) | 2014-02-19 |
| CN1849513A (zh) | 2006-10-18 |
| CN1849513B (zh) | 2011-09-21 |
| EP1644741B1 (de) | 2011-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |