ATE541035T1 - Modifizierte creatininamid-hydrolase mit verbesserter substrataffinität und reagenszusammensetzung zur bestimmung von creatinin - Google Patents
Modifizierte creatininamid-hydrolase mit verbesserter substrataffinität und reagenszusammensetzung zur bestimmung von creatininInfo
- Publication number
- ATE541035T1 ATE541035T1 AT07742029T AT07742029T ATE541035T1 AT E541035 T1 ATE541035 T1 AT E541035T1 AT 07742029 T AT07742029 T AT 07742029T AT 07742029 T AT07742029 T AT 07742029T AT E541035 T1 ATE541035 T1 AT E541035T1
- Authority
- AT
- Austria
- Prior art keywords
- creatinine
- hydrolase
- determination
- modified
- reagent composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006120313 | 2006-04-25 | ||
| JP2006247681 | 2006-09-13 | ||
| JP2006303451 | 2006-11-09 | ||
| PCT/JP2007/058594 WO2007125824A1 (ja) | 2006-04-25 | 2007-04-20 | 基質との親和性が向上したクレアチニンアミドヒドロラーゼ改変体、および、クレアチニン測定用試薬組成物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE541035T1 true ATE541035T1 (de) | 2012-01-15 |
Family
ID=38655350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07742029T ATE541035T1 (de) | 2006-04-25 | 2007-04-20 | Modifizierte creatininamid-hydrolase mit verbesserter substrataffinität und reagenszusammensetzung zur bestimmung von creatinin |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7816116B2 (de) |
| EP (1) | EP2011868B1 (de) |
| JP (1) | JP4214264B2 (de) |
| CN (1) | CN101426911B (de) |
| AT (1) | ATE541035T1 (de) |
| WO (1) | WO2007125824A1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009041409A1 (ja) * | 2007-09-27 | 2009-04-02 | Toyo Boseki Kabushiki Kaisha | クレアチニンアミドヒドロラーゼ改変体 |
| RU2354645C1 (ru) * | 2007-11-21 | 2009-05-10 | Закрытое Акционерное Общество "Вертекс" | Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием |
| WO2010074591A1 (ru) * | 2008-12-24 | 2010-07-01 | Закрытое Акционерное Общество "Beptekc" | Амиды креатина, способ их получения, средство, обладающее нейропротекторным действием |
| CN101587076B (zh) * | 2009-06-05 | 2011-12-14 | 深圳大学 | 定量检测肌氨酸含量的方法及反应试剂盒 |
| CN104133057B (zh) * | 2009-07-23 | 2016-09-07 | 深圳迈瑞生物医疗电子股份有限公司 | 一种消除临床检验中抗坏血酸干扰的方法、试剂及试剂盒 |
| CN103013941A (zh) * | 2012-12-28 | 2013-04-03 | 卫生部北京医院 | 一种制备肌氨酸氧化酶的方法及应用 |
| JP6514849B2 (ja) * | 2014-03-03 | 2019-05-15 | 学校法人東京薬科大学 | 低温における酵素活性を向上させた好熱菌由来酵素の改変体の取得方法、及び低温における酵素活性が向上しているサーマス・サーモフィラス由来３−イソプロピルリンゴ酸脱水素酵素の改変体 |
| JP6049795B2 (ja) * | 2014-04-10 | 2016-12-21 | ヤマサ醤油株式会社 | Ｌ−グルタミン測定キット |
| JP2021509289A (ja) * | 2017-12-21 | 2021-03-25 | メオン・メディカル・ソリューションズ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング・ウント・コムパニー・コマンディットゲゼルシャフトＭＥＯＮ Ｍｅｄｉｃａｌ Ｓｏｌｕｔｉｏｎｓ ＧｍｂＨ ＆ Ｃｏ．ＫＧ | クレアチニンデイミナーゼおよびその使用 |
| JP7276327B2 (ja) * | 2018-05-10 | 2023-05-18 | 東洋紡株式会社 | 生体成分測定試薬キットの感度低下抑制方法 |
| JP2019195300A (ja) * | 2018-05-10 | 2019-11-14 | 東洋紡株式会社 | 測定感度を改善した生体成分測定キット及び生体成分測定方法 |
| CN115820614A (zh) * | 2022-10-21 | 2023-03-21 | 武汉瀚海新酶生物科技有限公司 | 肌酐酶的制备方法及发酵培养基 |
| CN117802076B (zh) * | 2023-12-29 | 2024-08-27 | 南京诺唯赞生物科技股份有限公司 | 一种高活性的肌酐酶及其冻干剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51115989A (en) | 1975-04-05 | 1976-10-13 | Noda Sangyo Kagaku Kenkyusho | Process for preparing creatinine amide hydrolase |
| JP2527035B2 (ja) | 1989-06-16 | 1996-08-21 | 東洋紡績株式会社 | クレアチニン・アミドヒドロラ―ゼをコ―ドする遺伝子を含有するｄｎａ断片、該ｄｎａ断片を有する組換えベクタ―及び該組換えベクタ―を有する形質転換体、並びにクレアチニン・アミドヒドロラ―ゼの製造方法 |
| CA2404293C (en) | 2001-09-20 | 2007-05-15 | F. Hoffmann-La Roche Ag | Variants of an erwinia-type creatinase |
-
2007
- 2007-04-20 EP EP07742029A patent/EP2011868B1/de not_active Not-in-force
- 2007-04-20 WO PCT/JP2007/058594 patent/WO2007125824A1/ja not_active Ceased
- 2007-04-20 CN CN2007800145598A patent/CN101426911B/zh active Active
- 2007-04-20 AT AT07742029T patent/ATE541035T1/de active
- 2007-04-20 US US12/297,572 patent/US7816116B2/en active Active
- 2007-04-20 JP JP2007111753A patent/JP4214264B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP4214264B2 (ja) | 2009-01-28 |
| CN101426911A (zh) | 2009-05-06 |
| JP2008136477A (ja) | 2008-06-19 |
| EP2011868A1 (de) | 2009-01-07 |
| CN101426911B (zh) | 2013-05-01 |
| US20090170145A1 (en) | 2009-07-02 |
| US7816116B2 (en) | 2010-10-19 |
| EP2011868A4 (de) | 2009-04-29 |
| WO2007125824A1 (ja) | 2007-11-08 |
| EP2011868B1 (de) | 2012-01-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE541035T1 (de) | Modifizierte creatininamid-hydrolase mit verbesserter substrataffinität und reagenszusammensetzung zur bestimmung von creatinin | |
| ATE522812T1 (de) | Verfahren und zusammensetzung zum bestimmen von homocystein | |
| ATE485401T1 (de) | Neue primer und sonden zum nachweis von parvovirus b19 | |
| ATE489482T1 (de) | Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon | |
| WO2008105896A3 (en) | Analyte determination utilizing mass tagging reagents comprising a non-encoded detectable label | |
| CY1111229T1 (el) | Μεθοδος προσδιορισμου ρευματοειδους αρθριτιδας με μετρηση αντι-ccp και ιντερλευκλινης 6 | |
| WO2010065781A3 (en) | Lateral flow strip assay with immobilized conjugate | |
| ATE541054T1 (de) | Bio-barcode erkennung für zielmoleküle | |
| WO2005106036A3 (en) | Methods and compositions for assaying analytes | |
| ATE548467T1 (de) | Verfahren zur identifizierung von biomarkern mit eignung bei der diagnose biologischer zustände | |
| NZ598226A (en) | Method and apparatus for conducting an assay | |
| ATE437237T1 (de) | Verfahren zur messung von hochdichtem lipoproteincholesterol | |
| Cetecioğlu et al. | Biogeographical distribution and diversity of bacterial and archaeal communities within highly polluted anoxic marine sediments from the Marmara Sea | |
| WO2009034842A1 (ja) | 核酸検出方法、および核酸検出キット | |
| WO2007035864A3 (en) | Electrophoresis standards, methods and kits | |
| MX2009010751A (es) | Composiciones y metodos de deteccion. | |
| ATE519116T1 (de) | Verfahren zur normierung der konzentration von analyten in einer urinprobe | |
| ATE546550T1 (de) | Verfahren zum nachweis von hpv sowie sonden, primer und kits | |
| ATE347105T1 (de) | Verfahren, assay und kit zur quantifizierung von hiv-proteasehemmer | |
| SI1721162T1 (sl) | Postopek za ugotavljanje revmatoidnega artritisa z merjenjem anti-CCP in serumskega amiloida A | |
| ATE466105T1 (de) | Verfahren, zusammensetzungen und kits zur anreicherung und zum nachweis von mikroorganismen | |
| ATE414786T1 (de) | Verfahren zur erkennung eines ganzen homocysteins | |
| ATE495267T1 (de) | Diagnostisches verfahren zum nachweis von helicobacter pylori | |
| DE60232466D1 (de) | Verfahren zum testen von weizen | |
| ATE482283T1 (de) | Verfahren, biosensoren und kits zum nachweis und zur identifizierung von pilzen |