ATE523500T1 - Chinazolinon- und isochinolinon-acetamid-derivate - Google Patents
Chinazolinon- und isochinolinon-acetamid-derivateInfo
- Publication number
- ATE523500T1 ATE523500T1 AT07842157T AT07842157T ATE523500T1 AT E523500 T1 ATE523500 T1 AT E523500T1 AT 07842157 T AT07842157 T AT 07842157T AT 07842157 T AT07842157 T AT 07842157T AT E523500 T1 ATE523500 T1 AT E523500T1
- Authority
- AT
- Austria
- Prior art keywords
- isoquinolinone
- quinazolinone
- acetamide derivatives
- acetamide
- derivatives
- Prior art date
Links
- AVRPFRMDMNDIDH-UHFFFAOYSA-N 1h-quinazolin-2-one Chemical compound C1=CC=CC2=NC(O)=NC=C21 AVRPFRMDMNDIDH-UHFFFAOYSA-N 0.000 title 1
- WDORHSVOZYQOQO-UHFFFAOYSA-N acetamide;2h-isoquinolin-1-one Chemical class CC(N)=O.C1=CC=C2C(=O)NC=CC2=C1 WDORHSVOZYQOQO-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84371806P | 2006-09-11 | 2006-09-11 | |
| PCT/US2007/078022 WO2008033764A2 (en) | 2006-09-11 | 2007-09-10 | Quinazolinone and isoquinolinone acetamide derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE523500T1 true ATE523500T1 (de) | 2011-09-15 |
Family
ID=39184483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07842157T ATE523500T1 (de) | 2006-09-11 | 2007-09-10 | Chinazolinon- und isochinolinon-acetamid-derivate |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7820649B2 (de) |
| EP (1) | EP2069315B1 (de) |
| JP (1) | JP5256202B2 (de) |
| KR (1) | KR20090107994A (de) |
| CN (1) | CN101600698B (de) |
| AR (1) | AR062731A1 (de) |
| AT (1) | ATE523500T1 (de) |
| AU (1) | AU2007296634B2 (de) |
| CA (1) | CA2663161C (de) |
| CL (1) | CL2007002635A1 (de) |
| CO (1) | CO6160322A2 (de) |
| EC (1) | ECSP099177A (de) |
| IL (1) | IL197530A0 (de) |
| MX (1) | MX2009002686A (de) |
| NO (1) | NO20091012L (de) |
| NZ (1) | NZ575426A (de) |
| PE (1) | PE20080841A1 (de) |
| RU (1) | RU2009113612A (de) |
| TW (1) | TW200827352A (de) |
| WO (1) | WO2008033764A2 (de) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010229035A (ja) * | 2007-08-01 | 2010-10-14 | Taisho Pharmaceutical Co Ltd | ピリドピリミジン−４−オン誘導体 |
| WO2009130231A1 (en) * | 2008-04-24 | 2009-10-29 | Glaxo Group Limited | Pyrrolo [1, 2-a] pyrazine derivatives as vasopressin vib receptor antagonists |
| JP5369721B2 (ja) * | 2009-01-30 | 2013-12-18 | 大正製薬株式会社 | ピリドピリミジン−４−オン誘導体 |
| US8841289B2 (en) | 2009-10-13 | 2014-09-23 | Merck Sharp & Dohme B.V. | Heterocyclic derivatives |
| PL2623499T3 (pl) | 2010-10-01 | 2015-09-30 | Taisho Pharmaceutical Co Ltd | Pochodne 1,2,4-triazolonu |
| WO2013062027A1 (ja) | 2011-10-27 | 2013-05-02 | 大正製薬株式会社 | アゾール誘導体 |
| NZ629944A (en) * | 2012-03-30 | 2016-02-26 | Taisho Pharmaceutical Co Ltd | Fused azole derivative |
| CN104364239B (zh) | 2012-06-13 | 2017-08-25 | 霍夫曼-拉罗奇有限公司 | 二氮杂螺环烷烃和氮杂螺环烷烃 |
| MX368615B (es) | 2012-09-25 | 2019-10-09 | Hoffmann La Roche | Derivados bicíclicos como inhibidores de la autotaxina (atx) que son inhibidores de la producción de ácido lisofosfatídico (lpa) y el uso de los mismos. |
| AR095079A1 (es) | 2013-03-12 | 2015-09-16 | Hoffmann La Roche | Derivados de octahidro-pirrolo[3,4-c]-pirrol y piridina-fenilo |
| DK3074400T3 (en) | 2013-11-26 | 2018-01-15 | Hoffmann La Roche | Octahydro-cyclobuta [1,2-c; 3,4-c '] dipyrrole derivatives as autotaxin inhibitors |
| EA032357B1 (ru) | 2014-03-26 | 2019-05-31 | Ф. Хоффманн-Ля Рош Аг | Конденсированные [1,4]диазепиновые соединения в качестве ингибиторов продукции аутотаксина (atx) и лизофосфатидиловой кислоты (lpa) |
| CA2937616A1 (en) | 2014-03-26 | 2015-10-01 | F. Hoffmann-La Roche Ag | Bicyclic compounds as autotaxin (atx) and lysophosphatidic acid (lpa) production inhibitors |
| EP3177616B1 (de) * | 2014-08-04 | 2021-02-24 | Sandoz AG | Neue routen von synthesen zur herstellung von suvorexant |
| US9617226B2 (en) | 2014-09-05 | 2017-04-11 | AbbVie Deutschland GmbH & Co. KG | Fused heterocyclic or carbocyclic compounds carrying a substituted cycloaliphatic radical and use thereof for treating vasopressin-related diseases |
| MA41898A (fr) * | 2015-04-10 | 2018-02-13 | Hoffmann La Roche | Dérivés de quinazolinone bicyclique |
| CA2992889A1 (en) | 2015-09-04 | 2017-03-09 | F. Hoffmann-La Roche Ag | Phenoxymethyl derivatives |
| JP6876685B2 (ja) | 2015-09-24 | 2021-05-26 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ａｔｘ阻害剤としての二環式化合物 |
| AU2016328436B2 (en) | 2015-09-24 | 2020-05-14 | F. Hoffmann-La Roche Ag | New bicyclic compounds as dual ATX/CA inhibitors |
| WO2017050732A1 (en) | 2015-09-24 | 2017-03-30 | F. Hoffmann-La Roche Ag | Bicyclic compounds as atx inhibitors |
| BR112017026682A2 (pt) | 2015-09-24 | 2018-08-14 | Hoffmann La Roche | novos compostos bicíclicos como inibidores de dupla ação de atx/ca |
| EP4006038A1 (de) | 2015-12-09 | 2022-06-01 | Cadent Therapeutics, Inc. | Thienopyrimidinon-nmda-rezeptor-modulatoren und verwendungen davon |
| JP7071917B2 (ja) | 2015-12-09 | 2022-05-19 | カデント セラピューティクス，インコーポレーテッド | ヘテロ芳香族ｎｍｄａ受容体モジュレーターおよびその使用 |
| US11274107B2 (en) | 2016-12-22 | 2022-03-15 | Cadent Therapeutics, Inc. | NMDA receptor modulators and uses thereof |
| RU2019132254A (ru) | 2017-03-16 | 2021-04-16 | Ф. Хоффманн-Ля Рош Аг | Гетероциклические соединения, пригодные в качестве дуальных ингибиторов atx/ca |
| JP7090099B2 (ja) | 2017-03-16 | 2022-06-23 | エフ．ホフマン－ラ ロシュ アーゲー | Ａｔｘインヒビターとしての新規二環式化合物 |
| AR115905A1 (es) | 2018-08-03 | 2021-03-10 | Cadent Therapeutics Inc | 5-(3-cloro-4-fluorofenil)-7-ciclopropil-3-(2-(3-fluoro-3-metilazetidin-1-il)-2-oxoetil)-3,7-dihidro-4h-pirrolo[2,3-d]pirimidin-4-ona como modulador de los receptores de nmda |
| CN111100063B (zh) * | 2018-10-25 | 2022-05-17 | 南京药石科技股份有限公司 | 一种合成2-氟甲基取代的吡咯烷、哌啶以及哌嗪衍生物的制备方法 |
| CN116751169B (zh) * | 2023-06-05 | 2025-08-29 | 重庆市畜牧科学院 | 一种n-(2-氧代丙基)乙酰胺衍生物及其制备方法和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2506767A1 (fr) * | 1981-05-26 | 1982-12-03 | Synthelabo | Derives heterocycliques d'amidoximes, leur preparation et leur application en therapeutique |
| RU2205831C2 (ru) | 1997-04-25 | 2003-06-10 | Янссен Фармацевтика Н.В. | Хиназолиноны, ингибирующие фарнезилтрансферазу |
| IL139199A (en) | 1999-11-02 | 2006-10-31 | Nihon Nohyaku Co Ltd | Derivatives of aminoquinazolinone (thion) or their salts, their intermediates, pesticides and method of use |
| FR2804114B1 (fr) * | 2000-01-25 | 2002-03-08 | Sanofi Synthelabo | Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant |
| FR2842527B1 (fr) | 2002-07-19 | 2005-01-28 | Sanofi Synthelabo | Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique |
| JP4533391B2 (ja) * | 2004-01-16 | 2010-09-01 | エフ．ホフマン−ラ ロシュ アーゲー | 中枢神経系疾患の処置のための５−ヒドロキシトリプタミンレセプター（５−ｈｔ）のモジュレーターとしての、１−ベンジル−５−ピペラジン−１−イル−３，４−ジヒドロ−１ｈ−キナゾリン−２−オン誘導体、ならびにそれぞれの１ｈ−ベンゾ（１，２，６）チアジアジン−２，２−ジオキシドおよび１，４−ジヒドロベンゾ（ｄ）（１，３）オキサジン−２−オン誘導体 |
| JPWO2005115993A1 (ja) * | 2004-05-31 | 2008-03-27 | 萬有製薬株式会社 | キナゾリン誘導体 |
| WO2006012577A2 (en) * | 2004-07-22 | 2006-02-02 | Bayer Pharmaceuticals Corporation | Quinazolinone derivatives useful for the regulation of glucose homeostasis and food intake |
| TW200643015A (en) * | 2005-03-11 | 2006-12-16 | Akzo Nobel Nv | 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives |
| EP2066640B1 (de) * | 2006-09-11 | 2011-09-07 | N.V. Organon | 2-(1-oxo-1h-isochinolin-2-yl) acetamid-derivate |
-
2007
- 2007-09-10 CN CN2007800416250A patent/CN101600698B/zh active Active
- 2007-09-10 MX MX2009002686A patent/MX2009002686A/es not_active Application Discontinuation
- 2007-09-10 KR KR1020097007035A patent/KR20090107994A/ko not_active Withdrawn
- 2007-09-10 AU AU2007296634A patent/AU2007296634B2/en not_active Ceased
- 2007-09-10 EP EP07842157A patent/EP2069315B1/de active Active
- 2007-09-10 WO PCT/US2007/078022 patent/WO2008033764A2/en not_active Ceased
- 2007-09-10 NZ NZ575426A patent/NZ575426A/en not_active IP Right Cessation
- 2007-09-10 JP JP2009527608A patent/JP5256202B2/ja not_active Expired - Fee Related
- 2007-09-10 RU RU2009113612/04A patent/RU2009113612A/ru unknown
- 2007-09-10 AT AT07842157T patent/ATE523500T1/de not_active IP Right Cessation
- 2007-09-10 CA CA2663161A patent/CA2663161C/en active Active
- 2007-09-10 US US11/852,762 patent/US7820649B2/en active Active
- 2007-09-11 PE PE2007001221A patent/PE20080841A1/es not_active Application Discontinuation
- 2007-09-11 TW TW096133906A patent/TW200827352A/zh unknown
- 2007-09-11 AR ARP070103999A patent/AR062731A1/es not_active Application Discontinuation
- 2007-09-11 CL CL2007002635A patent/CL2007002635A1/es unknown
-
2009
- 2009-03-06 NO NO20091012A patent/NO20091012L/no not_active Application Discontinuation
- 2009-03-11 EC EC2009009177A patent/ECSP099177A/es unknown
- 2009-03-11 IL IL197530A patent/IL197530A0/en unknown
- 2009-04-08 CO CO09036257A patent/CO6160322A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2007002635A1 (es) | 2009-10-23 |
| WO2008033764A2 (en) | 2008-03-20 |
| IL197530A0 (en) | 2009-12-24 |
| JP5256202B2 (ja) | 2013-08-07 |
| AU2007296634A1 (en) | 2008-03-20 |
| RU2009113612A (ru) | 2010-10-20 |
| US20080090802A1 (en) | 2008-04-17 |
| NO20091012L (no) | 2009-03-26 |
| CA2663161C (en) | 2014-10-28 |
| CA2663161A1 (en) | 2008-03-20 |
| US7820649B2 (en) | 2010-10-26 |
| AR062731A1 (es) | 2008-11-26 |
| EP2069315A4 (de) | 2010-11-03 |
| EP2069315A2 (de) | 2009-06-17 |
| ECSP099177A (es) | 2009-06-30 |
| JP2010502746A (ja) | 2010-01-28 |
| PE20080841A1 (es) | 2008-06-14 |
| WO2008033764A3 (en) | 2008-12-18 |
| NZ575426A (en) | 2010-09-30 |
| CN101600698B (zh) | 2012-01-11 |
| KR20090107994A (ko) | 2009-10-14 |
| EP2069315B1 (de) | 2011-09-07 |
| MX2009002686A (es) | 2009-10-13 |
| CO6160322A2 (es) | 2010-05-20 |
| AU2007296634B2 (en) | 2012-09-20 |
| CN101600698A (zh) | 2009-12-09 |
| TW200827352A (en) | 2008-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE523500T1 (de) | Chinazolinon- und isochinolinon-acetamid-derivate | |
| BRPI0720909A2 (pt) | derivados de isoquinolina e isoquinolinona substituídos | |
| DE602007010981D1 (de) | Cycloalkylaminsubstituierte isochinolin- und isochinolinonderivate | |
| DE602007010272D1 (de) | Parkhilfevorrichtung und parkhilfeverfahren | |
| DE602007010795D1 (de) | Blattsauger und -häcksler | |
| BRPI0716300A2 (pt) | Artigo e mistura | |
| SMT201400193B (it) | Isochinolinoni e chinazolinoni sostituiti | |
| DE602007003585D1 (de) | Klappbarer und höhenverstellbarer kinderwagen | |
| ATE531720T1 (de) | Aza-benzofuranylverbindungen und anwendungsverfahren dafür | |
| DK1984322T3 (da) | Benzamid- og heteroarenderivater | |
| ZA200903552B (en) | Substituted isoquinoline and isoquinolinone derivatives | |
| EP2122054A4 (de) | Vliestafel und konstruktionsverfahren dafür | |
| DE602007006394D1 (de) | Mikrofon und Befestigungsanordnung | |
| ATE413389T1 (de) | Chinazolinderivate | |
| BRPI0813355A2 (pt) | Compostos de quinazolinona e métodos de uso dos mesmos | |
| HRP20141261T1 (xx) | Spojevi tioninija i njihove uporabe | |
| CR9458A (es) | Quinolonas y naftiridonas 7-amino alquilidenil heterociclicas | |
| DE602007011305D1 (de) | Kaffee- und teedosiersystem | |
| DK2001891T3 (da) | Buprenorfinderivater samt anvendelser deraf | |
| SE0700997L (sv) | Fastsättningsapparat och -system | |
| DE602006015540D1 (de) | Durchführung und buchse | |
| EP2050739A4 (de) | Chinazolinderivat | |
| DE102007013751B8 (de) | Tiefpassfilter und Tiefpassfilter-Anordnung | |
| PL2314609T3 (pl) | Pochodne metastyny i ich zastosowanie | |
| DE112007001727A5 (de) | Fordereinheit und Forderverfahren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |