ATE523592T1 - Dehydratisierte chitosan-nanopartikel - Google Patents
Dehydratisierte chitosan-nanopartikelInfo
- Publication number
- ATE523592T1 ATE523592T1 AT08758308T AT08758308T ATE523592T1 AT E523592 T1 ATE523592 T1 AT E523592T1 AT 08758308 T AT08758308 T AT 08758308T AT 08758308 T AT08758308 T AT 08758308T AT E523592 T1 ATE523592 T1 AT E523592T1
- Authority
- AT
- Austria
- Prior art keywords
- nanoparticles
- dehydrated
- particles
- nucleic acid
- chitosan nanoparticles
- Prior art date
Links
- 239000002105 nanoparticle Substances 0.000 title abstract 4
- 229920001661 Chitosan Polymers 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 108020004459 Small interfering RNA Proteins 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity
- C12N2320/51—Methods for regulating/modulating their activity modulating the chemical stability, e.g. nuclease-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Nanotechnology (AREA)
- Optics & Photonics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Separation Of Suspended Particles By Flocculating Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200701004 | 2007-07-06 | ||
| PCT/DK2008/050171 WO2009006905A1 (en) | 2007-07-06 | 2008-07-04 | Dehydrated chitosan nanoparticles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE523592T1 true ATE523592T1 (de) | 2011-09-15 |
Family
ID=39790018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08758308T ATE523592T1 (de) | 2007-07-06 | 2008-07-04 | Dehydratisierte chitosan-nanopartikel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110033547A1 (de) |
| EP (1) | EP2164964B1 (de) |
| AT (1) | ATE523592T1 (de) |
| CA (1) | CA2729923A1 (de) |
| DK (1) | DK2164964T3 (de) |
| ES (1) | ES2376200T3 (de) |
| WO (1) | WO2009006905A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100272813A1 (en) | 2007-07-23 | 2010-10-28 | Aarhus Universitet | Nanoparticle-mediated treatment for inflammatory diseases |
| JP5804453B2 (ja) * | 2009-05-14 | 2015-11-04 | 国立大学法人 東京大学 | 結晶性ポリオール微粒子及びその調製方法 |
| WO2013042125A2 (en) * | 2011-09-21 | 2013-03-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Nano delivery systems |
| US20130122096A1 (en) * | 2011-11-14 | 2013-05-16 | Silenseed Ltd. | Compositions for drug delivery and methods of manufacturing and using same |
| EP2806896B1 (de) | 2012-01-27 | 2018-01-03 | F. Hoffmann-La Roche AG | Kovalent an kleinmolekülige integrinantagonisten gebundenes chitosan für gezielte abgabe |
| GB201220675D0 (en) * | 2012-11-16 | 2013-01-02 | Univ Singapore | Process and materials for medical applications |
| US20160130606A1 (en) * | 2013-06-10 | 2016-05-12 | Polyvalor, Société En Commandite | Freeze-dried polyelectrolyte complexes that maintain size and biological activity |
| WO2015123778A1 (en) * | 2014-02-20 | 2015-08-27 | Polyvalor, Limited Partnership | Freeze-dried polymer compositions for mixing with platelet rich plasma to form implants for tissue repair and/or compositions for therapeutic intra-articular injections |
| CN105031746B (zh) * | 2015-09-10 | 2017-11-03 | 李健 | 一种壳聚糖携载siRNA涂层血管支架及其制备方法 |
| GB201520600D0 (en) | 2015-11-23 | 2016-01-06 | Univ Leuven Kath | Treatment of central nervous tumours |
| MX2018013122A (es) | 2016-04-26 | 2019-03-28 | Viaqua Therapeutics Ltd | Composiciones y procedimientos para tratar infecciones viricas en gambas. |
| EP3585364B1 (de) | 2017-02-24 | 2021-04-28 | The Regents of the University of California | Partikeltropfenstrukturen und verfahren zur herstellung und verwendung davon |
| CN107875400B (zh) * | 2017-11-20 | 2020-10-30 | 南通大学 | 一种壳-核结构的siRNA仿病毒递送系统及应用 |
| KR20240019077A (ko) | 2021-04-14 | 2024-02-14 | 파틸리온 바이오사이언스 코포레이션 | 나노규모 반응 챔버 및 이를 사용하는 방법 |
| PE20241353A1 (es) | 2021-11-09 | 2024-07-03 | Viaqua Therapeutics Ltd | Composiciones para acuicultura |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE216264T1 (de) * | 1996-07-10 | 2002-05-15 | West Pharm Serv Drug Res Ltd | Gentherapiesystem zur zielung des endotheliums |
| JP2003265171A (ja) * | 2002-03-15 | 2003-09-24 | Koike Kagaku Kk | 遺伝子ドライパウダー及びその調製方法並びに遺伝子ドライパウダーの調製装置 |
| EP1898833A2 (de) * | 2005-06-03 | 2008-03-19 | Biohesion, Inc. | Mit einer hitzestabilen und chemisch resistenten polypeptidschicht beschichtete goldoberflächen und anwendungen davon |
| US20070299043A1 (en) * | 2005-10-03 | 2007-12-27 | Hunter William L | Anti-scarring drug combinations and use thereof |
| DOP2006000268A (es) * | 2005-12-22 | 2007-07-31 | Pfizer Prod Inc | Agentes antibacterianos |
| JP2007224012A (ja) * | 2006-01-30 | 2007-09-06 | Fujifilm Corp | 酵素架橋したタンパク質ナノ粒子 |
| CA2652530A1 (en) * | 2006-05-24 | 2007-11-29 | Advanced In Vitro Cell Technologies, S.L. | Nanoparticles of chitosan and hyaluronan for the administration of active molecules |
| US20100092572A1 (en) * | 2007-01-29 | 2010-04-15 | Peter Kaeuper | Chitosan-based colloidal particles for rna delivery |
-
2008
- 2008-07-04 DK DK08758308.4T patent/DK2164964T3/da active
- 2008-07-04 AT AT08758308T patent/ATE523592T1/de not_active IP Right Cessation
- 2008-07-04 ES ES08758308T patent/ES2376200T3/es active Active
- 2008-07-04 US US12/667,204 patent/US20110033547A1/en not_active Abandoned
- 2008-07-04 WO PCT/DK2008/050171 patent/WO2009006905A1/en not_active Ceased
- 2008-07-04 EP EP08758308A patent/EP2164964B1/de not_active Not-in-force
- 2008-07-04 CA CA2729923A patent/CA2729923A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2164964A1 (de) | 2010-03-24 |
| WO2009006905A1 (en) | 2009-01-15 |
| CA2729923A1 (en) | 2009-01-15 |
| US20110033547A1 (en) | 2011-02-10 |
| EP2164964B1 (de) | 2011-09-07 |
| ES2376200T3 (es) | 2012-03-09 |
| DK2164964T3 (da) | 2011-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |