ATE52519T1 - Renin hemmende verbindungen welche statin enthalten oder dessen derivate. - Google Patents

Renin hemmende verbindungen welche statin enthalten oder dessen derivate.

Info

Publication number: ATE52519T1
Authority: AT; Austria
Prior art keywords: alkyl; glutamic acid; lys; cycloalkylalkyl; phe
Prior art date: 1984-03-12

Application number

AT85301691T

Other languages

English (en)

Inventor

Jasjit Singh Bindra

Edward Fox Kleinman

Robert Louis Rosati

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-03-12

Filing date

1985-03-12

Publication date

1990-05-15

1985-03-12 Application filed by Pfizer filed Critical Pfizer

1985-03-12 Priority claimed from EP85301691A external-priority patent/EP0155809B1/de

1990-05-15 Application granted granted Critical

1990-05-15 Publication of ATE52519T1 publication Critical patent/ATE52519T1/de

Links

229940121710 HMGCoA reductase inhibitor Drugs 0.000 title 1
102100028255 Renin Human genes 0.000 title 1
108090000783 Renin Proteins 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 10
239000004220 glutamic acid Substances 0.000 abstract 6
-1 1,2,3,4-tetrahydroquinolin-1-yl Chemical group 0.000 abstract 5
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 4
125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 4
235000013922 glutamic acid Nutrition 0.000 abstract 3
125000000753 cycloalkyl group Chemical group 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 abstract 1
101100079984 Caenorhabditis elegans nhr-9 gene Proteins 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
102000004196 processed proteins & peptides Human genes 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Vascular Medicine (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Pyrrole Compounds (AREA)

AT85301691T 1984-03-12 1985-03-12 Renin hemmende verbindungen welche statin enthalten oder dessen derivate. ATE52519T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US58827984A	1984-03-12	1984-03-12
EP85301691A EP0155809B1 (de)	1984-03-12	1985-03-12	Renin hemmende Verbindungen welche Statin enthalten oder dessen Derivate

Publications (1)

Publication Number	Publication Date
ATE52519T1 true ATE52519T1 (de)	1990-05-15

Family

ID=24353222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85301691T ATE52519T1 (de)	1984-03-12	1985-03-12	Renin hemmende verbindungen welche statin enthalten oder dessen derivate.

Country Status (13)

Country	Link
KR (1)	KR870000371B1 (de)
AT (1)	ATE52519T1 (de)
DE (1)	DE3577562D1 (de)
ES (1)	ES8606397A1 (de)
GR (1)	GR850626B (de)
HU (1)	HU196833B (de)
IE (1)	IE57862B1 (de)
IL (1)	IL74572A (de)
NO (1)	NO850975L (de)
NZ (1)	NZ211403A (de)
PH (1)	PH23769A (de)
YU (1)	YU46085A (de)
ZA (1)	ZA851832B (de)

1985
- 1985-03-12 NO NO850975A patent/NO850975L/no unknown
- 1985-03-12 NZ NZ211403A patent/NZ211403A/xx unknown
- 1985-03-12 KR KR1019850001617A patent/KR870000371B1/ko not_active Expired
- 1985-03-12 ES ES541194A patent/ES8606397A1/es not_active Expired
- 1985-03-12 GR GR850626A patent/GR850626B/el unknown
- 1985-03-12 HU HU85911A patent/HU196833B/hu not_active IP Right Cessation
- 1985-03-12 AT AT85301691T patent/ATE52519T1/de not_active IP Right Cessation
- 1985-03-12 IL IL74572A patent/IL74572A/xx not_active IP Right Cessation
- 1985-03-12 PH PH31980A patent/PH23769A/en unknown
- 1985-03-12 IE IE640/85A patent/IE57862B1/en not_active IP Right Cessation
- 1985-03-12 ZA ZA851832A patent/ZA851832B/xx unknown
- 1985-03-12 DE DE8585301691T patent/DE3577562D1/de not_active Expired - Lifetime
- 1985-03-21 YU YU00460/85A patent/YU46085A/xx unknown

Also Published As

Publication number	Publication date
IE57862B1 (en)	1993-05-05
NO850975L (no)	1985-09-13
IE850640L (en)	1985-09-12
KR850006940A (ko)	1985-10-25
DE3577562D1 (de)	1990-06-13
IL74572A (en)	1989-09-28
HUT37442A (en)	1985-12-28
ZA851832B (en)	1986-10-29
HU196833B (en)	1989-01-30
PH23769A (en)	1989-11-03
YU46085A (en)	1988-02-29
ES541194A0 (es)	1986-04-16
IL74572A0 (en)	1985-06-30
KR870000371B1 (ko)	1987-03-06
NZ211403A (en)	1989-01-27
ES8606397A1 (es)	1986-04-16
GR850626B (de)	1985-07-11

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Legal Events

Date	Code	Title	Description
1990-10-15	UEP	Publication of translation of european patent specification
1994-12-15	REN	Ceased due to non-payment of the annual fee