ZA851832B - Renin inhibitors containing statine or derivatives thereof - Google Patents
Renin inhibitors containing statine or derivatives thereofInfo
- Publication number
- ZA851832B ZA851832B ZA851832A ZA851832A ZA851832B ZA 851832 B ZA851832 B ZA 851832B ZA 851832 A ZA851832 A ZA 851832A ZA 851832 A ZA851832 A ZA 851832A ZA 851832 B ZA851832 B ZA 851832B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- glutamic acid
- lys
- cycloalkylalkyl
- phe
- Prior art date
Links
- 239000002461 renin inhibitor Substances 0.000 title 1
- 229940086526 renin-inhibitors Drugs 0.000 title 1
- DFVFTMTWCUHJBL-BQBZGAKWSA-N statine Chemical compound CC(C)C[C@H](N)[C@@H](O)CC(O)=O DFVFTMTWCUHJBL-BQBZGAKWSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 10
- 239000004220 glutamic acid Substances 0.000 abstract 6
- -1 1,2,3,4-tetrahydroquinolin-1-yl Chemical group 0.000 abstract 5
- WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 abstract 4
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 4
- 235000013922 glutamic acid Nutrition 0.000 abstract 3
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- ODHCTXKNWHHXJC-VKHMYHEASA-N 5-oxo-L-proline Chemical compound OC(=O)[C@@H]1CCC(=O)N1 ODHCTXKNWHHXJC-VKHMYHEASA-N 0.000 abstract 1
- 101100079984 Caenorhabditis elegans nhr-9 gene Proteins 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/14—Angiotensins: Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58827984A | 1984-03-12 | 1984-03-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA851832B true ZA851832B (en) | 1986-10-29 |
Family
ID=24353222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA851832A ZA851832B (en) | 1984-03-12 | 1985-03-12 | Renin inhibitors containing statine or derivatives thereof |
Country Status (13)
| Country | Link |
|---|---|
| KR (1) | KR870000371B1 (de) |
| AT (1) | ATE52519T1 (de) |
| DE (1) | DE3577562D1 (de) |
| ES (1) | ES8606397A1 (de) |
| GR (1) | GR850626B (de) |
| HU (1) | HU196833B (de) |
| IE (1) | IE57862B1 (de) |
| IL (1) | IL74572A (de) |
| NO (1) | NO850975L (de) |
| NZ (1) | NZ211403A (de) |
| PH (1) | PH23769A (de) |
| YU (1) | YU46085A (de) |
| ZA (1) | ZA851832B (de) |
-
1985
- 1985-03-12 NO NO850975A patent/NO850975L/no unknown
- 1985-03-12 NZ NZ211403A patent/NZ211403A/xx unknown
- 1985-03-12 KR KR1019850001617A patent/KR870000371B1/ko not_active Expired
- 1985-03-12 ES ES541194A patent/ES8606397A1/es not_active Expired
- 1985-03-12 GR GR850626A patent/GR850626B/el unknown
- 1985-03-12 HU HU85911A patent/HU196833B/hu not_active IP Right Cessation
- 1985-03-12 AT AT85301691T patent/ATE52519T1/de not_active IP Right Cessation
- 1985-03-12 IL IL74572A patent/IL74572A/xx not_active IP Right Cessation
- 1985-03-12 PH PH31980A patent/PH23769A/en unknown
- 1985-03-12 IE IE640/85A patent/IE57862B1/en not_active IP Right Cessation
- 1985-03-12 ZA ZA851832A patent/ZA851832B/xx unknown
- 1985-03-12 DE DE8585301691T patent/DE3577562D1/de not_active Expired - Lifetime
- 1985-03-21 YU YU00460/85A patent/YU46085A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IE57862B1 (en) | 1993-05-05 |
| NO850975L (no) | 1985-09-13 |
| IE850640L (en) | 1985-09-12 |
| KR850006940A (ko) | 1985-10-25 |
| DE3577562D1 (de) | 1990-06-13 |
| IL74572A (en) | 1989-09-28 |
| HUT37442A (en) | 1985-12-28 |
| HU196833B (en) | 1989-01-30 |
| PH23769A (en) | 1989-11-03 |
| YU46085A (en) | 1988-02-29 |
| ES541194A0 (es) | 1986-04-16 |
| IL74572A0 (en) | 1985-06-30 |
| KR870000371B1 (ko) | 1987-03-06 |
| NZ211403A (en) | 1989-01-27 |
| ES8606397A1 (es) | 1986-04-16 |
| ATE52519T1 (de) | 1990-05-15 |
| GR850626B (de) | 1985-07-11 |
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