ATE526036T1 - Reduzierung der interferenz zwischen ölhaltigen adjuvanzien und surfactanthaltigen antigenen - Google Patents

Reduzierung der interferenz zwischen ölhaltigen adjuvanzien und surfactanthaltigen antigenen

Info

Publication number
ATE526036T1
ATE526036T1 AT06795518T AT06795518T ATE526036T1 AT E526036 T1 ATE526036 T1 AT E526036T1 AT 06795518 T AT06795518 T AT 06795518T AT 06795518 T AT06795518 T AT 06795518T AT E526036 T1 ATE526036 T1 AT E526036T1
Authority
AT
Austria
Prior art keywords
reducing interference
surfactant containing
containing antigens
oil adjuvants
adjuvants
Prior art date
Application number
AT06795518T
Other languages
English (en)
Inventor
Mario Contorni
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37684892&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE526036(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB0515906.6A external-priority patent/GB0515906D0/en
Priority claimed from GB0522599A external-priority patent/GB0522599D0/en
Priority claimed from GB0523923A external-priority patent/GB0523923D0/en
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Application granted granted Critical
Publication of ATE526036T1 publication Critical patent/ATE526036T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AT06795518T 2005-08-02 2006-08-02 Reduzierung der interferenz zwischen ölhaltigen adjuvanzien und surfactanthaltigen antigenen ATE526036T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0515906.6A GB0515906D0 (en) 2005-08-02 2005-08-02 Mixtures of antigen and adjuvant
GB0522599A GB0522599D0 (en) 2005-11-04 2005-11-04 Adjuvants and antigens
GB0523923A GB0523923D0 (en) 2005-11-24 2005-11-24 Adjuvants and antigens
PCT/IB2006/002581 WO2007015167A2 (en) 2005-08-02 2006-08-02 Reducing interference between oil-containing adjuvants and surfactant-containing antigens

Publications (1)

Publication Number Publication Date
ATE526036T1 true ATE526036T1 (de) 2011-10-15

Family

ID=37684892

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06795518T ATE526036T1 (de) 2005-08-02 2006-08-02 Reduzierung der interferenz zwischen ölhaltigen adjuvanzien und surfactanthaltigen antigenen

Country Status (21)

Country Link
US (1) US20090220547A1 (de)
EP (1) EP1909830B1 (de)
JP (1) JP2009503051A (de)
KR (1) KR101321732B1 (de)
CN (1) CN103690945A (de)
AP (1) AP2745A (de)
AT (1) ATE526036T1 (de)
AU (1) AU2006274647B2 (de)
BR (1) BRPI0614254A2 (de)
CA (1) CA2617362A1 (de)
CY (1) CY1112149T1 (de)
DK (1) DK1909830T3 (de)
EA (1) EA014314B1 (de)
IL (1) IL189102A (de)
MX (1) MX2008001527A (de)
NO (1) NO20081033L (de)
NZ (1) NZ565512A (de)
PL (1) PL1909830T3 (de)
PT (1) PT1909830E (de)
SI (1) SI1909830T1 (de)
WO (1) WO2007015167A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101443064B1 (ko) 2008-08-28 2014-09-19 노파르티스 아게 과-생산 효모 유래 스쿠알렌의 제조
ES2731636T3 (es) 2011-03-11 2019-11-18 Km Biologics Co Ltd Composición adyuvante que contiene citrulina
FR3002454B1 (fr) 2013-02-26 2015-04-10 Commissariat Energie Atomique Composition immunogene sous forme d'emulsion
US9968673B2 (en) 2013-02-26 2018-05-15 Commissariat á l'ènergie atomique et aux ènergies alternatives Immunogenic composition in emulsion form comprising two dispersed phases, one comprising an antigen and the other comprising an immunostimulating agent
EP3377114B1 (de) * 2015-11-18 2020-07-08 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Immunogene zusammensetzung in form einer emulsion mit zwei dispergierten phasen, eine mit einem antigen und die andere mit einer immunostimulierenden verbindung
FR3043558B1 (fr) * 2015-11-18 2017-12-29 Commissariat Energie Atomique Composition immunogene sous forme d'emulsion comprenant deux phases dispersees, l'une comprenant un antigene et l'autre comprenant un agent immunostimulant
JP7555929B2 (ja) * 2018-12-24 2024-09-25 遠大賽威信生命科学（南京）有限公司 Ｂ型肝炎を治療するための薬物製剤、その製造方法及び用途
TW202245835A (zh) * 2021-02-04 2022-12-01 美商默沙東有限責任公司 用於肺炎球菌結合物疫苗之奈米乳化液佐劑組合物

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3435112A (en) * 1966-06-21 1969-03-25 Norden Lab Inc Repository vaccine and method of preparing the same
US4199565A (en) * 1979-03-26 1980-04-22 Merck & Co., Inc. Liposome particle containing viral or bacterial antigenic subunit
US4683294A (en) * 1985-04-03 1987-07-28 Smith Kline Rit, S.A. Process for the extraction and purification of proteins from culture media producing them
US4649192A (en) * 1985-05-30 1987-03-10 Smith Kline-Rit Method for the isolation and purification of hepatitis B surface antigen using polysorbate
CA2017507C (en) * 1989-05-25 1996-11-12 Gary Van Nest Adjuvant formulation comprising a submicron oil droplet emulsion
US5709879A (en) * 1990-06-29 1998-01-20 Chiron Corporation Vaccine compositions containing liposomes
GB9503863D0 (en) * 1995-02-25 1995-04-19 Smithkline Beecham Biolog Vaccine compositions
US5718904A (en) * 1995-06-02 1998-02-17 American Home Products Corporation Adjuvants for viral vaccines
ATE353225T1 (de) * 1995-11-30 2007-02-15 Chemo Sero Therapeut Res Inst Öladjuvierter impfstoff und verfahren zu seiner herstellung
GB9616351D0 (en) * 1996-08-02 1996-09-11 Smithkline Beecham Biolog Vaccine composition
CN1326564C (zh) * 1997-04-01 2007-07-18 科里克萨有限公司 单磷酰基脂质a的水性免疫佐剂组合物
GB9718901D0 (en) * 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
EP1096954B1 (de) * 1998-07-14 2004-10-06 Wyeth Holdings Corporation Monophosphoryllipid a enthaltende adjuvans- und impfstoffzusammensetzungen
KR100629028B1 (ko) * 1998-10-16 2006-09-26 글락소스미스클라인 바이오로지칼즈 에스.에이. 애쥬번트 시스템 및 백신
PT1187629E (pt) * 1999-04-19 2005-02-28 Glaxosmithkline Biolog Sa Composicao adjuvante que compreende saponina e um oligonucleotido imunoestimulador
PL355287A1 (en) * 1999-09-24 2004-04-05 Smithkline Beecham Biologicals S.A. Intranasal influenza virus vaccine
JP2001151699A (ja) * 1999-11-29 2001-06-05 Nippon Surfactant Kogyo Kk 動物用ワクチンのオイルアジュバント
KR20010105882A (ko) * 2000-05-19 2001-11-29 배길훈 스티어링 칼럼 구조
UA79735C2 (uk) * 2000-08-10 2007-07-25 Глаксосмітклайн Байолоджікалз С.А. Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах
MXPA03002643A (es) * 2000-09-28 2003-06-19 Chiron Corp Composiciones de microparticulas y metodos para producirlas.
US6479282B1 (en) * 2001-05-09 2002-11-12 Bio Merieux Hbc expression and diagnostic and therapeutic uses
MY134424A (en) * 2001-05-30 2007-12-31 Saechsisches Serumwerk Stable influenza virus preparations with low or no amount of thiomersal
NZ560930A (en) * 2005-02-16 2011-06-30 Novartis Vaccines & Diagnostic Hepatitis B virus vaccine comprising a hepatitis B virus surface antigen, aluminium phosphate, 3-O-deacylated monophosphoryl lipid A and a triethylammonium ion
CA2605179A1 (en) * 2005-04-18 2006-10-26 Novartis Vaccines And Diagnostics, Inc. Expressing hepatitis b virus surface antigen for vaccine preparation

Also Published As

Publication number Publication date
WO2007015167A3 (en) 2007-05-03
KR20080038384A (ko) 2008-05-06
US20090220547A1 (en) 2009-09-03
NZ565512A (en) 2011-08-26
EP1909830B1 (de) 2011-09-28
SI1909830T1 (sl) 2012-01-31
IL189102A (en) 2011-09-27
BRPI0614254A2 (pt) 2011-03-15
IL189102A0 (en) 2008-08-07
CY1112149T1 (el) 2015-11-04
AU2006274647B2 (en) 2013-01-10
DK1909830T3 (da) 2011-12-19
CA2617362A1 (en) 2007-02-08
EP1909830A2 (de) 2008-04-16
WO2007015167A2 (en) 2007-02-08
PL1909830T3 (pl) 2012-02-29
MX2008001527A (es) 2008-04-04
JP2009503051A (ja) 2009-01-29
AP2745A (en) 2013-09-30
PT1909830E (pt) 2011-11-24
AU2006274647A1 (en) 2007-02-08
EA200800509A1 (ru) 2008-10-30
EA014314B1 (ru) 2010-10-29
NO20081033L (no) 2008-02-27
KR101321732B1 (ko) 2013-10-29
CN103690945A (zh) 2014-04-02

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