ATE527061T1 - Vorrichtung und verfahren zur probenverarbeitung - Google Patents

Vorrichtung und verfahren zur probenverarbeitung

Info

Publication number
ATE527061T1
ATE527061T1 AT01994360T AT01994360T ATE527061T1 AT E527061 T1 ATE527061 T1 AT E527061T1 AT 01994360 T AT01994360 T AT 01994360T AT 01994360 T AT01994360 T AT 01994360T AT E527061 T1 ATE527061 T1 AT E527061T1
Authority
AT
Austria
Prior art keywords
sample
thermal cycling
vessel
processing station
processing
Prior art date
Application number
AT01994360T
Other languages
English (en)
Inventor
Shuqi Chen
Original Assignee
Chen & Chen Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chen & Chen Llc filed Critical Chen & Chen Llc
Application granted granted Critical
Publication of ATE527061T1 publication Critical patent/ATE527061T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B01L2200/027—Fluid interfacing between devices or objects, e.g. connectors, inlet details for microfluidic devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0874—Three dimensional network
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0655—Valves, specific forms thereof with moving parts pinch valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1002—Reagent dispensers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
AT01994360T 2000-12-29 2001-12-26 Vorrichtung und verfahren zur probenverarbeitung ATE527061T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25902500P 2000-12-29 2000-12-29
US09/782,732 US6780617B2 (en) 2000-12-29 2001-02-13 Sample processing device and method
PCT/US2001/049707 WO2002057798A2 (en) 2000-12-29 2001-12-26 Sample processing device and method

Publications (1)

Publication Number Publication Date
ATE527061T1 true ATE527061T1 (de) 2011-10-15

Family

ID=26947016

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01994360T ATE527061T1 (de) 2000-12-29 2001-12-26 Vorrichtung und verfahren zur probenverarbeitung

Country Status (8)

Country Link
US (5) US6780617B2 (de)
EP (1) EP1347833B1 (de)
JP (1) JP4205947B2 (de)
CN (1) CN100457274C (de)
AT (1) ATE527061T1 (de)
AU (1) AU2002246765A1 (de)
CA (1) CA2433347C (de)
WO (1) WO2002057798A2 (de)

Families Citing this family (189)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030096232A1 (en) * 1997-12-19 2003-05-22 Kris Richard M. High throughput assay system
US20100105572A1 (en) * 1997-12-19 2010-04-29 Kris Richard M High throughput assay system
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
DE69940647D1 (de) 1998-05-01 2009-05-07 Gen Probe Inc Automatische diagnostische Analysevorrichtung
US6780617B2 (en) * 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
EP1005656B1 (de) * 1998-06-24 2014-05-21 Chen & Chen, LLC Testsystem für flüssige proben
US7799521B2 (en) * 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
US8518328B2 (en) * 2005-12-27 2013-08-27 Honeywell International Inc. Fluid sensing and control in a fluidic analyzer
AU2002259017B2 (en) * 2001-04-26 2007-08-16 Boston Biomedica, Inc. Multichamber device and uses thereof for processing of biological samples
EP1415113B1 (de) * 2001-07-16 2011-08-31 Idaho Technology, Inc. Temperaturwechselsystem und verwendungsverfahren
EP1427531B1 (de) 2001-09-11 2016-10-19 Iquum, Inc. Probenbehälter
KR100488281B1 (ko) 2001-09-15 2005-05-10 아람 바이오시스템 주식회사 열 대류를 이용한 염기서열 증폭 방법 및 장치
GB2403536B (en) * 2002-04-23 2006-11-08 Idaho Technology Inc Sample withdrawal and dispensing device
US7919308B2 (en) * 2002-06-14 2011-04-05 Agilent Technologies, Inc. Form in place gaskets for assays
EP1603674B1 (de) * 2003-02-05 2016-01-06 Iquum, Inc. Probenverarbeitung
EP1654066B1 (de) 2003-07-31 2014-11-12 Handylab, Inc. Verarbeitung von teilchenhaltigen proben
DE10353985A1 (de) * 2003-11-19 2005-06-23 Olympus Biosystems Gmbh Einrichtung und Verfahren zum Manipulieren und Analysieren von Mikroobjekten auf Grundlage eines zumindest bereichsweise als fluidisches Mikrosystem oder/und Chipsystem ausgeführten Mikrosystems
WO2005056748A1 (en) * 2003-12-08 2005-06-23 Covaris, Inc. Apparatus and methods for sample preparation
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
US8685724B2 (en) 2004-06-01 2014-04-01 Kwalata Trading Limited In vitro techniques for use with stem cells
WO2005121963A2 (en) * 2004-06-07 2005-12-22 Iquum, Inc. Sample multiprocessing
US7585663B2 (en) * 2004-08-26 2009-09-08 Applied Biosystems, Llc Thermal device, system, and method, for fluid processing device
GB0419294D0 (en) * 2004-08-31 2004-09-29 Evogen Ltd Reaction vessel
CA2583406A1 (en) * 2004-09-20 2007-01-04 Boston Microfluidics Microfluidic device for detecting soluble molecules
US20060094028A1 (en) * 2004-11-04 2006-05-04 Welch Allyn, Inc. Rapid diagnostic assay
KR100612879B1 (ko) * 2004-12-06 2006-08-14 삼성전자주식회사 폐쇄 시스템에서 펌프와 밸브의 제어를 통한 혼성화 장치
US7794659B2 (en) 2005-03-10 2010-09-14 Gen-Probe Incorporated Signal measuring system having a movable signal measuring device
KR100624464B1 (ko) * 2005-03-29 2006-09-19 삼성전자주식회사 반자동 마이크로 칩 개폐장치
CA2607661C (en) 2005-05-09 2017-08-08 Idaho Technology, Inc. A device and method for two-stage nucleic acid amplification
MX2007013985A (es) 2005-05-09 2008-02-22 Theranos Inc Sistemas de fluidos de punto de cuidado y usos de los mismos.
US20110206643A1 (en) * 2005-06-02 2011-08-25 In Motion Investment, Ltd. Automated Cell Therapy System
US8182767B2 (en) * 2005-12-27 2012-05-22 Honeywell International Inc. Needle-septum interface for a fluidic analyzer
US7485153B2 (en) * 2005-12-27 2009-02-03 Honeywell International Inc. Fluid free interface for a fluidic analyzer
US20080003564A1 (en) * 2006-02-14 2008-01-03 Iquum, Inc. Sample processing
TW200734462A (en) 2006-03-08 2007-09-16 In Motion Invest Ltd Regulating stem cells
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US9040288B2 (en) 2006-03-24 2015-05-26 Handylab, Inc. Integrated system for processing microfluidic samples, and method of using the same
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US8232091B2 (en) 2006-05-17 2012-07-31 California Institute Of Technology Thermal cycling system
JP2009537152A (ja) * 2006-05-17 2009-10-29 カリフォルニア インスティテュート オブ テクノロジー 温度サイクルシステム
ATE496987T1 (de) 2006-05-22 2011-02-15 Biovest Int Inc Ausserkapilläres fluidzirkulationssystem und - verfahren
DE112007001597A5 (de) * 2006-06-27 2009-07-16 Zenteris Gmbh Kühleinrichtung für eine Reaktionskammer zum Prozessieren eines Biochips und Verfahren zum Ansteuern einer solchen Kühleinrichtung
WO2008012550A2 (en) * 2006-07-28 2008-01-31 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
WO2008030433A2 (en) * 2006-09-06 2008-03-13 Canon U.S. Life Sciences, Inc. Chip and cartridge design configuration for performing micro-fluidic assays
US20080069732A1 (en) * 2006-09-20 2008-03-20 Robert Yi Diagnostic test system
US10753927B2 (en) 2006-09-22 2020-08-25 ALERE TECHNOLOGIES GmbH Methods for detecting an analyte
EP2080025A4 (de) * 2006-10-27 2011-12-07 Montecito Bio Sciences Ltd Tragbare vorrichtung für verbesserte probenanalyse
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
WO2008060604A2 (en) * 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US9102911B2 (en) 2009-05-15 2015-08-11 Biofire Diagnostics, Llc High density self-contained biological analysis
ES2809168T3 (es) 2006-11-15 2021-03-03 Biofire Diagnostics Llc Análisis biológico autónomo de alta densidad
EP2458382B1 (de) * 2006-11-22 2017-12-20 CLONDIAG GmbH Analysevorrichtung mit mehrere Testzonen, Verfahren mit der Vorrichtung
JP2008175608A (ja) * 2007-01-17 2008-07-31 Yokogawa Electric Corp 化学反応用カートリッジ及びその使用方法
WO2008104056A1 (en) 2007-02-26 2008-09-04 Groupe Gecko Alliance Inc. A method, device and system for use in configuring a bathing unit controller
JP2008272645A (ja) * 2007-04-27 2008-11-13 Yokogawa Electric Corp 内容物移送装置および化学処理システム
JPWO2008146754A1 (ja) 2007-05-23 2010-08-19 トラストメディカル株式会社 反応液用容器、及びそれを用いる反応促進装置、並びにその方法
CN103157400B (zh) 2007-06-21 2014-12-24 简·探针公司 用于将容器暴露于多个热区的仪器和方法
IL184183A0 (en) * 2007-06-25 2007-10-31 Benjamin Alspector Bi directional transfer of an aliquot of fluid between compartments
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
ES2648798T3 (es) 2007-07-13 2018-01-08 Handylab, Inc. Materiales de captura de polinucleótidos y métodos de utilización de los mismos
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
CN101358823B (zh) * 2007-07-30 2011-01-05 鸿富锦精密工业(深圳)有限公司 元件排列治具
CN104307581B (zh) * 2007-08-09 2017-04-12 诺思可有限公司 关联的多参数单细胞测定及残余生物材料回收的方法和装置
WO2009024773A1 (en) 2007-08-17 2009-02-26 Diagnostics For The Real World, Ltd Device, system and method for processing a sample
JP5479672B2 (ja) * 2007-09-27 2014-04-23 シスメックス株式会社 血液または尿の分析装置およびデータ処理装置
CN104297506B (zh) 2007-10-02 2017-05-03 赛拉诺斯股份有限公司 模块化现场护理装置及其应用
WO2009105499A1 (en) * 2008-02-20 2009-08-27 Termaat Joel R Thermocycler and sample vessel for rapid amplification of dna
WO2009111475A2 (en) 2008-03-03 2009-09-11 Heatflow Technologies, Inc. Heat flow polymerase chain reaction systems and methods
US20110127222A1 (en) * 2008-03-19 2011-06-02 Cynvenio Biosystems, Inc. Trapping magnetic cell sorting system
DE102008025992B4 (de) * 2008-05-30 2011-01-27 Siemens Healthcare Diagnostics Gmbh Titerplatte und Verfahren zur Detektion eines Analyten
US9724695B2 (en) 2008-06-23 2017-08-08 Canon U.S. Life Sciences, Inc. Systems and methods for amplifying nucleic acids
US20100099074A1 (en) * 2008-07-25 2010-04-22 Garry Nolan Collection device and method for stimulating and stabilizing a biological sample
DE102009001261A1 (de) * 2008-10-06 2010-04-15 Aj Ebiochip Gmbh Vorrichtung und Verfahren zur Ausführung mehrerer paralleler PCR-Reaktionen im Durchflussverfahren
FR2938062B1 (fr) 2008-11-05 2014-02-28 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
FR2938063B1 (fr) 2008-11-05 2014-09-19 Commissariat Energie Atomique Dispositif de preparation et/ou de traitement d'un echantillon biologique
CA2750900C (en) * 2009-01-30 2017-03-28 Gen-Probe Incorporated Systems and methods for detecting a signal and applying thermal energy to a signal transmission element
CN202830041U (zh) * 2009-04-03 2013-03-27 Illumina公司 用于加热生物样本的设备
WO2010132756A2 (en) * 2009-05-14 2010-11-18 Streck, Inc. Sample processing cassette, system, and method
CN201837588U (zh) * 2009-09-09 2011-05-18 海利克斯公司 用于多个反应的光学系统
KR102032523B1 (ko) * 2010-01-12 2019-10-15 아람 바이오시스템 주식회사 2단 열대류 장치 및 그 사용법
WO2011086497A2 (en) 2010-01-12 2011-07-21 Ahram Biosystems, Inc. Three-stage thermal convection apparatus and uses thereof
DE102010003365A1 (de) * 2010-03-26 2011-09-29 Micropelt Gmbh Vorrichtung zur Durchführung der PCR und PCR-Verfahren
EP2374541A1 (de) * 2010-04-06 2011-10-12 Symbion Medical Systems Sàrl Einweg-Ausgabekartusche für medizinische Testgeräte
FR2959312B1 (fr) 2010-04-23 2023-01-20 Biomerieux Sa Dispositif de preparation et/ou de traitement d'un echantillon biologique
JP5281042B2 (ja) * 2010-06-15 2013-09-04 株式会社日立ハイテクノロジーズ 電気泳動媒体用容器及び電気泳動装置の駆動方法
KR20130029128A (ko) 2010-07-23 2013-03-21 베크만 컬터, 인코포레이티드 실시간 pcr용 용기
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
CN102884171B (zh) * 2010-08-30 2014-08-13 松下健康医疗器械株式会社 微生物数量测定用单元、使用它的微生物数量测定装置、以及使用它的微生物数量测定方法
JP2013545475A (ja) * 2010-11-30 2013-12-26 クワンタムディーエックス・グループ・リミテッド マイクロ流体多重温度可撓性反応デバイスの設計、製造及び使用
DE102011011912B4 (de) * 2011-02-21 2020-09-03 Eppendorf Ag Laborgerät mit Deckel und Pressanordnung und Verfahren zum Anpressen
EP2678664B1 (de) 2011-02-24 2019-08-07 Gen-Probe Incorporated Systeme und verfahren zur unterscheidung optischer signale mit verschiedenen modulationsfrequenzen bei einem optischen signaldetektor
EP3270141B1 (de) 2011-03-08 2020-05-20 Universite Laval Zentripetale fluidikvorrichtung
CN106190806B (zh) 2011-04-15 2018-11-06 贝克顿·迪金森公司 扫描实时微流体热循环仪和用于同步的热循环和扫描光学检测的方法
US8889086B2 (en) * 2011-04-21 2014-11-18 Streck, Inc. Sample tube having particular utility for nucleic acid amplification
US10076757B2 (en) 2011-05-24 2018-09-18 Molecular Biology Systems B.V. System for and method of changing temperatures of substances
CA2835654A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
WO2012171030A2 (en) 2011-06-10 2012-12-13 Biovest International, Inc. Method and apparatus for antibody production and purification
EP3225972B1 (de) 2011-09-09 2025-03-19 Gen-Probe Incorporated Verfahren zur automatisierten probenhandhabung
WO2013067202A1 (en) 2011-11-04 2013-05-10 Handylab, Inc. Polynucleotide sample preparation device
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
KR20140091033A (ko) 2011-11-07 2014-07-18 베크만 컬터, 인코포레이티드 검체 컨테이너 검출
WO2013070755A2 (en) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Centrifuge system and workflow
EP3373015A1 (de) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotierungssystem und arbeitsablauf
US9910054B2 (en) 2011-11-07 2018-03-06 Beckman Coulter, Inc. System and method for processing samples
CN104040352B (zh) 2011-11-07 2016-09-07 贝克曼考尔特公司 机械臂
CA2854768C (en) 2011-11-10 2021-08-17 David E. Jones Loading vials
US9040000B2 (en) * 2012-01-26 2015-05-26 Heatflow Technologies Inc. Sample container with sensor receptacle and methods of use
CN107367626B (zh) 2012-04-18 2024-02-06 拜奥法尔诊断有限责任公司 微点样装置
USD690025S1 (en) * 2012-06-11 2013-09-17 Streck, Inc. Sample tube
CN103115807A (zh) * 2012-07-17 2013-05-22 上海聚阵生物科技有限公司 一种生物芯片点样仪
US20140200167A1 (en) 2012-08-01 2014-07-17 Nanomdx, Inc. Functionally integrated device for multiplex genetic identification
US9932632B2 (en) 2012-08-10 2018-04-03 Streck, Inc. Real-time optical system for polymerase chain reaction
CA2920957A1 (en) 2012-08-28 2014-03-06 Biovest International, Inc. Biomanufacturing suite and methods for large-scale production of cells, viruses, and biomolecules
GB201217390D0 (en) * 2012-09-28 2012-11-14 Agplus Diagnostics Ltd Test device and sample carrier
US9731847B2 (en) * 2012-12-11 2017-08-15 Ortho-Clinical Diagnostics, Inc. Method for holding multiple types of diagnostic test consumables in a random access single container
CN107831324B (zh) 2013-03-15 2021-11-19 雅培制药有限公司 具有后面可进入轨道系统的自动化诊断分析仪及相关方法
CN105190317B (zh) 2013-03-15 2018-05-04 雅培制药有限公司 具有预处理转盘的诊断分析机及相关方法
CN105378487B (zh) 2013-03-15 2018-08-21 雅培制药有限公司 具有竖直布置的圆盘传送带的自动化诊断分析仪及相关方法
JP5391350B2 (ja) * 2013-04-15 2014-01-15 株式会社日立ハイテクノロジーズ 電気泳動媒体用容器及び電気泳動装置の駆動方法
WO2014210593A1 (en) 2013-06-28 2014-12-31 Streck, Inc. Devices for real-time polymerase chain reaction
US9168533B2 (en) * 2013-07-17 2015-10-27 CrackerBio, Inc. Thermal cycler device
GB201320542D0 (en) * 2013-11-21 2014-01-01 Randox Lab Ltd Assay fluid delivery system
WO2015138343A1 (en) 2014-03-10 2015-09-17 Click Diagnostics, Inc. Cartridge-based thermocycler
US9445482B2 (en) 2014-05-23 2016-09-13 Gecko Alliance Group Inc. Light bulb and method and system for use in configuring same
US9641959B2 (en) 2014-05-23 2017-05-02 Gecko Alliance Group Inc. Household for industrial device including programmable controller and method device and system for use in configuring same
US9623415B2 (en) 2014-12-31 2017-04-18 Click Diagnostics, Inc. Devices and methods for molecular diagnostic testing
WO2016151538A2 (en) * 2015-03-25 2016-09-29 Krugel Daniel Rudolph A method and device for detecting a material
CN104815559A (zh) * 2015-05-21 2015-08-05 厦门大学 一种水样悬浮颗粒物过滤装置
US9222935B1 (en) * 2015-05-28 2015-12-29 Pixcell Medical Technologies Ltd Fluid sample analysis system
US11260386B2 (en) 2015-06-05 2022-03-01 The Emerther Company Component of a device, a device, and a method for purifying and testing biomolecules from biological samples
CN107923766A (zh) * 2015-07-29 2018-04-17 赛诺菲-安万特德国有限公司 用于药物输送装置的传感器装置
CN105181378B (zh) * 2015-09-29 2019-02-01 贵州大学 一种多功能分层取样器
USD799715S1 (en) 2015-10-23 2017-10-10 Gene POC, Inc. Fluidic centripetal device
CN115181781A (zh) 2015-11-02 2022-10-14 拜奥法尔诊断有限责任公司 困难样品类型的样品制备
CN105441321B (zh) * 2015-12-11 2018-06-08 杭州优思达生物技术有限公司 全自动一体化核酸分析仪
WO2017147085A1 (en) 2016-02-22 2017-08-31 Biofire Defense, Llc Devices and methods for rapid pcr
GB201604062D0 (en) 2016-03-09 2016-04-20 Cell Therapy Catapult Ltd A device for heating or cooling a sample
JP6979029B2 (ja) 2016-03-24 2021-12-08 バイオファイア・ダイアグノスティクス,リミテッド・ライアビリティ・カンパニー 定量的増幅方法
US11786906B2 (en) 2016-04-15 2023-10-17 Biofire Defense, Llc Resistive heaters and anisotropic thermal transfer
CN105861304B (zh) * 2016-04-22 2018-06-12 成都瀚辰光翼科技有限责任公司 一种pcr热循环装置
WO2017185067A1 (en) 2016-04-22 2017-10-26 Click Diagnostics, Inc. Printed circuit board heater for an amplification module
WO2017197040A1 (en) 2016-05-11 2017-11-16 Click Diagnostics, Inc. Devices and methods for nucleic acid extraction
US9933445B1 (en) 2016-05-16 2018-04-03 Hound Labs, Inc. System and method for target substance identification
EP3478857A1 (de) 2016-06-29 2019-05-08 Click Diagnostics, Inc. Vorrichtungen und verfahren zur detektion von molekülen unter verwendung einer durchflusszelle
USD800331S1 (en) 2016-06-29 2017-10-17 Click Diagnostics, Inc. Molecular diagnostic device
USD800914S1 (en) 2016-06-30 2017-10-24 Click Diagnostics, Inc. Status indicator for molecular diagnostic device
USD800913S1 (en) 2016-06-30 2017-10-24 Click Diagnostics, Inc. Detection window for molecular diagnostic device
CA3302085A1 (en) 2016-07-28 2026-03-02 Biofire Defense, Llc Self-contained nucleic acid processing
CN106486238A (zh) * 2016-09-13 2017-03-08 深圳振华富电子有限公司 一种叠层片式磁珠及其制备方法
CN106635781A (zh) * 2016-10-27 2017-05-10 杭州安杰思生物科技有限公司 一种分子诊断系统的温度切换机构
PL235210B1 (pl) * 2016-12-21 2020-06-15 Genomtec Spolka Akcyjna Sposób detekcji materiału genetycznego w próbce biologicznej oraz urządzenie do jego realizacji
US10427162B2 (en) 2016-12-21 2019-10-01 Quandx Inc. Systems and methods for molecular diagnostics
CN107129933A (zh) * 2017-05-08 2017-09-05 大连大学 一种基于电驱动的数字微流控pcr芯片装置
CA3064762A1 (en) 2017-05-24 2018-11-29 Northwestern University Devices and methods for rapid sample processing and analysis
JP6823204B2 (ja) 2017-05-24 2021-01-27 バイオファイアー・ディフェンス・エルエルシー アレイのポイント・オブ・ユース排出のためのシステムおよび方法
KR102000661B1 (ko) * 2017-06-26 2019-10-01 (주)아이엠 정량분석 진단기기
EP3421131A1 (de) 2017-06-30 2019-01-02 Blink AG Probenkartusche zum inkubieren und/oder zur analyse einer dispersion von partikeln, zellen oder tropfen
US11398296B2 (en) 2017-07-21 2022-07-26 Biofire Diagnostics, Llc Detection using concurrent melting curves
WO2019050976A1 (en) * 2017-09-06 2019-03-14 Access Medical Systems, Ltd. FERROMAGNETIC ROTORS FOR STIRRING A LIQUID IN A MICROCAVITY
CN110651033B (zh) * 2017-09-19 2022-11-01 瑞基海洋生物科技股份有限公司 生化反应装置的加热机构
MX2020004783A (es) 2017-11-09 2020-08-13 Visby Medical Inc Dispositivo portatil para el diagnostico molecular y metodos para la deteccion de virus objetivo.
CN108279146B (zh) * 2018-01-30 2021-03-26 北京航空航天大学 一种用于氧化锌基陶瓷成分测试的前处理方法
JP7590954B2 (ja) 2018-04-20 2024-11-27 バイオファイア・ダイアグノスティクス,リミテッド・ライアビリティ・カンパニー シーケンシングデータの正規化および定量化のための方法
WO2019236978A1 (en) 2018-06-07 2019-12-12 Biofire Diagnostics, Llc Rapid thermocycling methods
JP2021534804A (ja) 2018-09-03 2021-12-16 ビスビュー メディカル,インコーポレイテッド 抗生物質感受性検査のための装置および方法
US11396809B2 (en) * 2018-11-16 2022-07-26 Halliburton Energy Services, Inc. In-situ reservoir fluid analysis system
CN109434625A (zh) * 2018-12-03 2019-03-08 攀枝花钢城集团有限公司 光谱金相磨样机的磨样辅助机构
CN113727841B (zh) 2018-12-21 2024-05-14 拜奥法尔诊断有限责任公司 用于反应容器的原位密封的设备、方法和系统
CA3125250A1 (en) * 2019-01-04 2020-07-09 Oribiotech Ltd Cell processing unit, cell processing system and methods of use thereof
EP3908833A4 (de) 2019-01-11 2022-08-10 Fredsense Technologies Corp. Systeme und verfahren zur voltammetrischen detektion
US11007524B2 (en) * 2019-01-18 2021-05-18 National Tsing Hua University Automatic microfluidic system for rapid personalized drug screening and testing method for personalized antibiotic susceptibility
US20200245898A1 (en) 2019-01-31 2020-08-06 Hound Labs, Inc. Single-use Microfluidic Cartridge for Detection of Target Chemical Presence in Human Breath
US11977086B2 (en) 2019-03-21 2024-05-07 Hound Labs, Inc. Biomarker detection from breath samples
US12263478B2 (en) 2019-04-28 2025-04-01 Visby Medical, Inc. Molecular diagnostic devices with digital detection capability and wireless connectivity
EP4085149A4 (de) 2020-01-03 2024-03-06 Visby Medical, Inc. Vorrichtungen und verfahren zur prüfung von antibiotischer suszeptibilität
US11933731B1 (en) 2020-05-13 2024-03-19 Hound Labs, Inc. Systems and methods using Surface-Enhanced Raman Spectroscopy for detecting tetrahydrocannabinol
WO2021254518A1 (zh) 2020-06-19 2021-12-23 中国疾病预防控制中心病毒病预防控制所 一种样品处理及检测装置
CA3181809A1 (en) * 2020-06-29 2022-01-06 Aaron Kauffmann Devices and methods for plasma separation and metering
US20220042117A1 (en) 2020-08-06 2022-02-10 Roche Molecular Systems, Inc. COMPOSITIONS AND METHODS FOR THE SIMULTANEOUS DETECTION OF INFLUENZA A, INFLUENZA B, AND SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-CoV-2)
CN112553072B (zh) * 2020-12-10 2022-04-08 上海艾众生物科技有限公司 用于生物反应器罐外循环的微流道动力设备
US12392769B1 (en) 2021-01-12 2025-08-19 Hound Labs, Inc. Ambient contamination in breath analyte detection and measurement
USD1064314S1 (en) 2021-08-13 2025-02-25 Visby Medical, Inc. Molecular diagnostic device
EP4382915A1 (de) 2022-12-09 2024-06-12 Maxim Buzuk Versorgungsort-gerät zur durchführung verschiedener biochemischer reaktionen
EP4744774A4 (de) * 2023-08-23 2026-07-15 Bgi Res Shenzhen Flüssigkeitsübertragungsvorrichtung, reaktionsvorrichtung und analysevorrichtung
CN120310647A (zh) * 2024-04-17 2025-07-15 首都体育学院 一种细胞共培养平板流动腔及其梯度流体切应力刺激方法
DE102024132689A1 (de) * 2024-11-08 2026-05-13 Detechgene GmbH System zur LAMP Amplifikation von DNA und/oder RNA

Family Cites Families (146)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895475A (en) 1956-12-03 1959-07-21 Everett L Cole Container for collecting, storing and dispensing biological fluids
US3036894A (en) * 1958-10-22 1962-05-29 Jasper A Forestiere Method of using testing containers
US3260413A (en) 1964-08-31 1966-07-12 Scientific Industries Automatic chemical analyzer
USRE29725E (en) 1966-04-26 1978-08-08 E. I. Du Pont De Nemours And Company Analytical test pack and process for analysis
US3697227A (en) 1966-05-13 1972-10-10 Westinghouse Electric Corp Chemical constituent sampler
FR1513306A (fr) 1966-09-08 1968-02-16 Automatisme Cie Gle Perfectionnements aux installations d'analyses
BE702970A (de) 1966-09-08 1968-02-23
US3441205A (en) 1966-10-10 1969-04-29 Marvin Kendall Young Jr Method for separating sediment from supernatant fluid
US3607097A (en) 1967-08-09 1971-09-21 Philips Corp Analyzer for liquid samples
US3579303A (en) 1968-03-06 1971-05-18 Donald E Pickering System for handling specimens and other substances in medicine and physical sciences
FR2035058A1 (de) * 1969-03-19 1970-12-18 American Optical Corp
US3736933A (en) * 1970-12-02 1973-06-05 B Szabo Burstable seamed hypodermic applicators
CA983358A (en) 1971-09-08 1976-02-10 Kenneth D. Bagshawe Performance of chemical or biological reactions
US3819158A (en) 1972-08-17 1974-06-25 Lever Brothers Ltd Devices for blending materials
US3918913A (en) 1974-12-02 1975-11-11 Lilly Co Eli Sampler-injector for liquid chromatography
US4038030A (en) 1975-04-10 1977-07-26 American Hospital Supply Corporation Profile analysis pack and method
US4065263A (en) 1976-04-02 1977-12-27 Woodbridge Iii Richard G Analytical test strip apparatus
US4166457A (en) 1976-08-16 1979-09-04 University Of Utah Research Institute Fluid self-sealing bioelectrode
DE2753865A1 (de) 1977-12-02 1979-06-07 Ultrakust Geraetebau Verfahren und vorrichtung zum handhaben von milchproben
DE2804881C3 (de) 1978-02-04 1980-08-07 Fa. Carl Zeiss, 7920 Heidenheim Gerät zur automatischen Analyse von flüssigen Proben
US4187861A (en) 1978-02-21 1980-02-12 Heffernan Bart T Blood sample handling apparatus and method
US4381208A (en) 1978-08-15 1983-04-26 Lucas Industries Limited Method of making a ribbon cable
US4266559A (en) 1979-04-02 1981-05-12 American Hospital Supply Corporation Blood sampler
US4596271A (en) 1980-10-02 1986-06-24 Brundage Robert W Fluid pressure device
US4329698A (en) 1980-12-19 1982-05-11 International Business Machines Corporation Disposable cartridge for ink drop printer
US4426451A (en) 1981-01-28 1984-01-17 Eastman Kodak Company Multi-zoned reaction vessel having pressure-actuatable control means between zones
JPS5818167A (ja) 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd 分析フイルム及びこれを用いる分析方法
US4446232A (en) 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
US5073484A (en) 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
US4752449A (en) 1982-10-15 1988-06-21 Hemotec, Inc. Apparatus for coagulation detection by gas flow or plunger sensing techniques
US4608275A (en) 1983-07-01 1986-08-26 Macdermid, Incorporated Oxidizing accelerator
EP0139373A1 (de) 1983-08-26 1985-05-02 The Regents Of The University Of California System für vielfache Immunoassays
JPS61247965A (ja) 1985-04-25 1986-11-05 Susumu Kogyo Kk 酵素免疫測定法
US4695430A (en) 1985-10-31 1987-09-22 Bio/Data Corporation Analytical apparatus
FR2590673B1 (fr) 1985-11-05 1988-09-16 Bally Philippe Dispositif de test autonome miniaturise a usage unique
JPS62226057A (ja) 1986-03-28 1987-10-05 Minoru Tomita 全血用赤血球の凝集率測定方法及びその装置
US5057438A (en) 1986-09-24 1991-10-15 Agency Of Industrial Science And Technology Electrophoretic antigen-antibody determination with laminate of multiple membranes
US5714380A (en) 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US4846005A (en) 1986-12-12 1989-07-11 Baxter International Inc. Set with attachable sample cell
US4900321A (en) 1986-12-12 1990-02-13 Baxter International Inc. Set with integrally formed sample cell
US4820297A (en) 1986-12-12 1989-04-11 Baxter International Inc. Fluid delivery system with integrally formed sample cell
AT391213B (de) 1987-05-12 1990-09-10 Avl Verbrennungskraft Messtech Einrichtung zur wahlweisen beschickung eines analysengeraetes
US5178832A (en) 1987-09-28 1993-01-12 The Texas A&M University System Selective immobilization and detection of mycotoxins in solution
US4874691A (en) 1987-10-16 1989-10-17 Quadra Logic Technologies Inc. Membrane-supported immunoassays
DE3737604A1 (de) 1987-11-05 1989-05-24 Biotechnolog Forschung Gmbh Geraet zur fliess-injektions-analyse
CA1339723C (en) 1988-01-19 1998-03-17 Philip Mcmahon Immunoassay with multiple test spots
US5137804A (en) 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5019348A (en) 1988-05-26 1991-05-28 Beckman Instruments, Inc. Automated chemical conversion unit in a peptide/protein sequenator
US5061445A (en) 1988-11-03 1991-10-29 Igen, Inc. Apparatus for conducting measurements of electrochemiluminescent phenomena
US5354440A (en) 1988-11-29 1994-10-11 Isco, Inc. Capillary electrophoresis technique
US5229297A (en) 1989-02-03 1993-07-20 Eastman Kodak Company Containment cuvette for PCR and method of use
CA1338505C (en) 1989-02-03 1996-08-06 John Bruce Findlay Containment cuvette for pcr and method of use
CA1328359C (en) 1989-03-27 1994-04-12 Michael D. Mintz Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US5120662A (en) 1989-05-09 1992-06-09 Abbott Laboratories Multilayer solid phase immunoassay support and method of use
US5504007A (en) 1989-05-19 1996-04-02 Becton, Dickinson And Company Rapid thermal cycle apparatus
CA1329698C (en) * 1989-06-12 1994-05-24 Mark Joseph Devaney, Jr. Temperature control device
US5089233A (en) * 1989-06-12 1992-02-18 Eastman Kodak Company Processing apparatus for a chemical reaction pack
GB8917963D0 (en) 1989-08-05 1989-09-20 Scras Apparatus for repeated automatic execution of a thermal cycle for treatment of biological samples
US5185127A (en) * 1989-09-21 1993-02-09 Becton, Dickinson And Company Test device including flow control means
CA2031108A1 (en) 1989-12-26 1991-06-27 Thomas William Glanville Chemical reaction pack and method of using same
US5098660A (en) 1990-01-08 1992-03-24 Eastman Kodak Company Transfer apparatus for chemical reaction pack
US5143084A (en) 1990-05-24 1992-09-01 Spacelabs, Inc. Disposable cartridge for sampling and analyzing body fluids
US5455175A (en) 1990-06-04 1995-10-03 University Of Utah Research Foundation Rapid thermal cycling device
US5187084A (en) 1990-06-22 1993-02-16 The Dow Chemical Company Automatic air temperature cycler and method of use in polymerose chain reaction
DE4029004C1 (de) 1990-09-13 1992-04-02 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften Ev, 3400 Goettingen, De
KR100236506B1 (ko) 1990-11-29 2000-01-15 퍼킨-엘머시터스인스트루먼츠 폴리머라제 연쇄 반응 수행 장치
US5709668A (en) 1991-01-16 1998-01-20 Senetek Plc Automatic medicament injector employing non-coring needle
US5244813A (en) 1991-01-25 1993-09-14 Trustees Of Tufts College Fiber optic sensor, apparatus, and methods for detecting an organic analyte in a fluid or vapor sample
FR2672231A1 (fr) 1991-02-01 1992-08-07 Eibet Appareil d'execution automatique repetee d'un cycle thermique, notamment pour l'amplification du nombre d'une sequence definie d'acide nucleique.
US5270183A (en) 1991-02-08 1993-12-14 Beckman Research Institute Of The City Of Hope Device and method for the automated cycling of solutions between two or more temperatures
US5258314A (en) * 1991-03-18 1993-11-02 Paradigm Biotechnologies Partnership Microprocessor-based biomedical monitoring apparatus and method
EP0504772A3 (en) 1991-03-18 1993-01-27 Paradigm Biotechnologies Partnership Analytical apparatus
DE4202850A1 (de) 1992-01-31 1993-08-05 Boehringer Mannheim Gmbh Analysenelement fuer immunoassays
US5422271A (en) 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
EP0688426A1 (de) 1993-03-08 1995-12-27 WAINWRIGHT, Norman Diagnostische chromatographie mittels ausgerichteten fasern
SE9301495D0 (sv) 1993-04-30 1993-04-30 Kabi Pharmacia Ab A device for metering and administrering a liquid preparation
WO1994026414A1 (en) 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
SE9302121D0 (sv) 1993-06-18 1993-06-18 Kabi Pharmacia Ab Apparatus for controlled delivery of liquids
US5491067A (en) 1993-07-15 1996-02-13 Ortho Diagnostic Systems Inc. Agglutination reaction and separation vessel
DE69429038T2 (de) 1993-07-28 2002-03-21 Pe Corporation (Ny), Norwalk Vorrichtung und Verfahren zur Nukleinsäurevervielfältigung
IL106662A (en) 1993-08-11 1996-10-31 Yissum Res Dev Co Install a flow cell to monitor blood or any single cell suspension under flow
CA2130013C (en) 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
US5374395A (en) 1993-10-14 1994-12-20 Amoco Corporation Diagnostics instrument
US5645801A (en) * 1993-10-21 1997-07-08 Abbott Laboratories Device and method for amplifying and detecting target nucleic acids
JP3346064B2 (ja) 1993-12-28 2002-11-18 セイコーエプソン株式会社 インクジェットカートリッジ
DE69517209T2 (de) * 1994-01-06 2000-11-23 Johnson & Johnson Clinical Diagnostics, Inc. Vorrichtung zum Erwärmen einer Flüssigkeitsführenden Kammer von einer Reaktionscuvette
DE69504031T2 (de) 1994-01-11 1999-03-18 Abbott Laboratories, Abbott Park, Ill. Vorrichtung und verfahren zur durchführung von nukleinsäueretests mittels temperaturzyklen
US6143263A (en) 1994-04-29 2000-11-07 The Babcock & Wilcox Company Method and system for SO2 and SO3 control by dry sorbent/reagent injection and wet scrubbing
US5508197A (en) 1994-07-25 1996-04-16 The Regents, University Of California High-speed thermal cycling system and method of use
US5658413A (en) * 1994-10-19 1997-08-19 Hewlett-Packard Company Miniaturized planar columns in novel support media for liquid phase analysis
US5571410A (en) * 1994-10-19 1996-11-05 Hewlett Packard Company Fully integrated miniaturized planar liquid sample handling and analysis device
JP2002514886A (ja) 1994-10-24 2002-05-21 プロメガ コーポレーション クロストリジウム・ディフィシル疾患の治療及び予防のためのワクチン及び抗トキシン
JPH08196299A (ja) 1995-01-26 1996-08-06 Tosoh Corp サーマルサイクリング反応装置及びこれに用いる反応容器
US5780222A (en) 1995-04-10 1998-07-14 Alpha Therapeutic Corporation Method of PCR testing of pooled blood samples
US5591573A (en) * 1995-04-10 1997-01-07 Alpha Therapeutic Corporation Method and system for testing blood samples
GB2303799B (en) 1995-07-29 1999-03-10 Siemens Plc Improvements in or relating to aqueous sample testing apparatus
GB2303916B (en) 1995-07-29 1999-03-03 Siemens Plc Improvements in or relating to aqueous sample testing apparatus
KR100469207B1 (ko) 1995-10-20 2005-03-16 화이자 헬스 에이비 전자식주입조정장치
US5847734A (en) 1995-12-04 1998-12-08 Pawlowski, Jr.; Norman E. Air purge system for an ink-jet printer
US6068751A (en) * 1995-12-18 2000-05-30 Neukermans; Armand P. Microfluidic valve and integrated microfluidic system
US5830657A (en) 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
ES2115521B1 (es) 1996-02-26 1999-02-16 Grifols Grupo Sa Dispositivo para la realizacion de reacciones eritrocitarias.
FR2746001B1 (fr) 1996-03-12 1998-06-12 Ensemble de chirurgie orthopedique pour prothese de hanche a col amovible
WO1997040939A1 (en) 1996-05-01 1997-11-06 Visible Genetics Inc. Method and apparatus for thermal cycling and for automated sample preparation with thermal cycling
US5913232A (en) 1996-05-20 1999-06-15 Sendx Medical, Inc. reference solution container for blood gas/electrolyte measuring system
DE69739357D1 (de) 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
US5985651A (en) 1996-06-17 1999-11-16 The Board Of Trustees Of The Leland Stanford Junior University Thermocycling apparatus and method
GB9618595D0 (en) 1996-09-06 1996-10-16 Central Research Lab Ltd Reaction cell
US6210036B1 (en) 1996-09-06 2001-04-03 Gerald P. Eberle Connector thermal sensor
GB9621357D0 (en) 1996-10-12 1996-12-04 Central Research Lab Ltd Heating apparatus
DE19646116A1 (de) 1996-11-08 1998-05-14 Eppendorf Geraetebau Netheler Temperierblock mit Aufnahmen
US6180698B1 (en) 1997-02-28 2001-01-30 Candescent Technologies Corporation Polycarbonate-containing liquid chemical formulation and method for making polycarbonate film
JP3428426B2 (ja) 1997-03-26 2003-07-22 株式会社日立製作所 検体分析システム
AU736484B2 (en) 1997-03-28 2001-07-26 Applied Biosystems, Llc Improvements in thermal cycler for PCR
US6186982B1 (en) 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
AU7477398A (en) 1997-05-09 1998-11-27 Regents Of The University Of California, The Peltier-assisted microfabricated reaction chambers for thermal cycling
US6194160B1 (en) 1998-03-19 2001-02-27 Immunetics, Inc. Systems and methods for rapid blot screening
US5866366A (en) 1997-07-01 1999-02-02 Smithkline Beecham Corporation gidB
US6300138B1 (en) * 1997-08-01 2001-10-09 Qualigen, Inc. Methods for conducting tests
WO1999033559A1 (en) 1997-12-24 1999-07-08 Cepheid Integrated fluid manipulation cartridge
US6066296A (en) 1997-09-23 2000-05-23 Array Medical, Inc. Sample addition, reagent application, and testing chamber
US5942432A (en) 1997-10-07 1999-08-24 The Perkin-Elmer Corporation Apparatus for a fluid impingement thermal cycler
US6111096A (en) * 1997-10-31 2000-08-29 Bbi Bioseq, Inc. Nucleic acid isolation and purification
US6251660B1 (en) 1997-11-25 2001-06-26 Mosaic Technologies, Inc. Devices and methods for detecting target molecules in biological samples
US6210369B1 (en) 1997-12-16 2001-04-03 Meridian Medical Technologies Inc. Automatic injector
US6300308B1 (en) 1997-12-31 2001-10-09 Board Of Regents, The University Of Texas System Methods and compositions for inducing autoimmunity in the treatment of cancers
ES2229465T3 (es) 1998-05-04 2005-04-16 F. Hoffmann-La Roche Ag Tremo-variador que tiene una tapa que se coloca automaticamente en posicion.
US7799521B2 (en) 1998-06-24 2010-09-21 Chen & Chen, Llc Thermal cycling
EP1005656B1 (de) 1998-06-24 2014-05-21 Chen & Chen, LLC Testsystem für flüssige proben
WO1999067647A1 (en) 1998-06-24 1999-12-29 Chen & Chen, Llc Multi-layer testing column
US6780617B2 (en) * 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
GB9814506D0 (en) 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
GB9819897D0 (en) 1998-09-11 1998-11-04 Seward Limited Devices for blending materials
WO2000023803A1 (en) 1998-10-16 2000-04-27 Millstein Larry S Methods of making patterned arrays of analyte-binding molecules
EP1000661A1 (de) 1998-10-29 2000-05-17 Hans-Knöll-Institut für Naturstoff-Forschung e.v. Ultradünnwandige Mehrfachlochplatte für Heizblock-Thermozyklen
US6250166B1 (en) 1999-06-04 2001-06-26 General Electric Company Simulated dovetail testing
US6159727A (en) 1999-06-04 2000-12-12 Clontech Laboratories, Inc. Hybridization chamber
WO2001007892A1 (en) 1999-07-27 2001-02-01 Esperion Therapeutics, Inc. Method and device for measurement of cholesterol efflux
US6719715B2 (en) 1999-09-16 2004-04-13 Vasogen Ireland Limited Apparatus and process for conditioning organic fluid
US6471069B2 (en) 1999-12-03 2002-10-29 Becton Dickinson And Company Device for separating components of a fluid sample
US6440072B1 (en) 2000-03-30 2002-08-27 Acuson Corporation Medical diagnostic ultrasound imaging system and method for transferring ultrasound examination data to a portable computing device
EP1415113B1 (de) * 2001-07-16 2011-08-31 Idaho Technology, Inc. Temperaturwechselsystem und verwendungsverfahren
EP1603674B1 (de) 2003-02-05 2016-01-06 Iquum, Inc. Probenverarbeitung
WO2005121963A2 (en) 2004-06-07 2005-12-22 Iquum, Inc. Sample multiprocessing
US20080003564A1 (en) 2006-02-14 2008-01-03 Iquum, Inc. Sample processing

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US20120276532A1 (en) 2012-11-01
US6964862B2 (en) 2005-11-15
US9662652B2 (en) 2017-05-30
JP2004518129A (ja) 2004-06-17
US20020086417A1 (en) 2002-07-04
US6780617B2 (en) 2004-08-24
EP1347833B1 (de) 2011-10-05
AU2002246765A1 (en) 2002-07-30
JP4205947B2 (ja) 2009-01-07
US20060154341A1 (en) 2006-07-13
US8148116B2 (en) 2012-04-03
CA2433347A1 (en) 2002-07-25
US7935504B2 (en) 2011-05-03
WO2002057798A3 (en) 2002-09-19
EP1347833A2 (de) 2003-10-01
US20110207121A1 (en) 2011-08-25
US20050019875A1 (en) 2005-01-27
WO2002057798A2 (en) 2002-07-25
CN1406154A (zh) 2003-03-26
CN100457274C (zh) 2009-02-04

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