ATE527264T1 - Kondensierte heterozyklische verbindungen als hemmer von proteinkinasen - Google Patents

Kondensierte heterozyklische verbindungen als hemmer von proteinkinasen

Info

Publication number
ATE527264T1
ATE527264T1 AT08780617T AT08780617T ATE527264T1 AT E527264 T1 ATE527264 T1 AT E527264T1 AT 08780617 T AT08780617 T AT 08780617T AT 08780617 T AT08780617 T AT 08780617T AT E527264 T1 ATE527264 T1 AT E527264T1
Authority
AT
Austria
Prior art keywords
inhibitors
heterocyclic compounds
protein kinases
condensed heterocyclic
compounds
Prior art date
Application number
AT08780617T
Other languages
English (en)
Inventor
Michael MICHAELIDES
Zhiqin Ji
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE527264T1 publication Critical patent/ATE527264T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT08780617T 2007-05-09 2008-05-09 Kondensierte heterozyklische verbindungen als hemmer von proteinkinasen ATE527264T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US91683807P 2007-05-09 2007-05-09
US91684607P 2007-05-09 2007-05-09
PCT/US2008/063197 WO2008141145A1 (en) 2007-05-09 2008-05-09 Condensed heterocyclic compounds as inhibitors of protein kinases

Publications (1)

Publication Number Publication Date
ATE527264T1 true ATE527264T1 (de) 2011-10-15

Family

ID=39650562

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08780617T ATE527264T1 (de) 2007-05-09 2008-05-09 Kondensierte heterozyklische verbindungen als hemmer von proteinkinasen

Country Status (8)

Country Link
EP (1) EP2150553B1 (de)
JP (1) JP5412424B2 (de)
CN (1) CN101730700A (de)
AT (1) ATE527264T1 (de)
CA (1) CA2685351A1 (de)
ES (1) ES2372559T3 (de)
MX (1) MX2009012079A (de)
WO (1) WO2008141145A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8624027B2 (en) * 2005-05-12 2014-01-07 Abbvie Inc. Combination therapy for treating cancer and diagnostic assays for use therein
US8124759B2 (en) 2007-05-09 2012-02-28 Abbott Laboratories Inhibitors of protein kinases
CN102532042A (zh) * 2010-12-30 2012-07-04 上海医药工业研究院 一种芳基脲类化合物、其中间体及其应用
JP2015532287A (ja) 2012-09-26 2015-11-09 ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア Ｉｒｅ１の調節

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA83509C2 (en) * 2003-10-15 2008-07-25 Оси Фармасьютикалз, Инк. Imidazopyrazines as tyrosine kinase inhibitors
EP2168968B1 (de) * 2004-04-02 2017-08-23 OSI Pharmaceuticals, LLC 6,6-bizylische ringsubstituierte heterobizyklische Proteinkinasehemmer
JP5052518B2 (ja) * 2005-10-06 2012-10-17 シェーリング コーポレイション プロテインキナーゼインヒビターとしてのピラゾロピリミジン
ES2365869T3 (es) * 2005-11-17 2011-10-11 OSI Pharmaceuticals, LLC COMPUESTOS BICÍCLICOS FUSIONADOS INHIBIDORES DE LA mTOR.
AR057960A1 (es) * 2005-12-02 2007-12-26 Osi Pharm Inc Inhibidores de proteina quinasa biciclicos
TW200738725A (en) * 2006-01-25 2007-10-16 Osi Pharm Inc Unsaturated mTOR inhibitors
EP1996193A2 (de) * 2006-03-13 2008-12-03 OSI Pharmaceuticals, Inc. Kombinierte behandlung mit einem egfr-kinase-hemmber und einem wirkstoff, der tumorzellen für die wirkung von egfr-kinase-hemmern sensibilisiert

Also Published As

Publication number Publication date
EP2150553B1 (de) 2011-10-05
CA2685351A1 (en) 2008-11-20
MX2009012079A (es) 2009-11-19
EP2150553A1 (de) 2010-02-10
JP2010526833A (ja) 2010-08-05
JP5412424B2 (ja) 2014-02-12
WO2008141145A1 (en) 2008-11-20
ES2372559T3 (es) 2012-01-23
CN101730700A (zh) 2010-06-09

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