ATE527353T1 - Pdgf-bindendes polypeptid aus protein a - Google Patents

Pdgf-bindendes polypeptid aus protein a

Info

Publication number
ATE527353T1
ATE527353T1 AT08862011T AT08862011T ATE527353T1 AT E527353 T1 ATE527353 T1 AT E527353T1 AT 08862011 T AT08862011 T AT 08862011T AT 08862011 T AT08862011 T AT 08862011T AT E527353 T1 ATE527353 T1 AT E527353T1
Authority
AT
Austria
Prior art keywords
pdgf
binding polypeptide
protein
growth factor
factor receptor
Prior art date
Application number
AT08862011T
Other languages
English (en)
Inventor
Malin Lindborg
Elin Gunneriusson
Christofer Lendel
Original Assignee
Affibody Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/002,972 external-priority patent/US8937047B2/en
Priority claimed from EP07150394A external-priority patent/EP2077272A1/de
Application filed by Affibody Ab filed Critical Affibody Ab
Application granted granted Critical
Publication of ATE527353T1 publication Critical patent/ATE527353T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/49—Platelet-derived growth factor [PDGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT08862011T 2007-12-19 2008-12-17 Pdgf-bindendes polypeptid aus protein a ATE527353T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12/002,972 US8937047B2 (en) 2007-12-19 2007-12-19 Biokinetics of fast-clearing polypeptides
EP07150394A EP2077272A1 (de) 2007-12-21 2007-12-21 Polypeptid-Bibliothek mit vorbestimmtem Gerüst
US917107P 2007-12-26 2007-12-26
PCT/EP2008/010776 WO2009077175A1 (en) 2007-12-19 2008-12-17 Polypeptide derived from protein a and able to bind pdgf

Publications (1)

Publication Number Publication Date
ATE527353T1 true ATE527353T1 (de) 2011-10-15

Family

ID=40547476

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08862011T ATE527353T1 (de) 2007-12-19 2008-12-17 Pdgf-bindendes polypeptid aus protein a

Country Status (5)

Country Link
EP (1) EP2231860B1 (de)
AT (1) ATE527353T1 (de)
DK (1) DK2231860T3 (de)
ES (1) ES2373832T3 (de)
WO (1) WO2009077175A1 (de)

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EP2072525A1 (de) 2007-12-21 2009-06-24 Affibody AB Neue Polypeptide mit Bindungsaffinität für HER2
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LT3553084T (lt) 2011-11-16 2023-03-10 Adrenomed Ag Anti-adrenomedulino (adm) antikūnas arba anti-adm antikūno fragmentas, arba anti-adm ne-ig karkasas, skirtas organų funkcijos sutrikimo arba organų nepakankamumo profilaktikai arba sumažinimui paciento, sergančio lėtine arba ūmine liga arba esančio ūminės būklės, organizme
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IL283215B2 (en) 2011-11-16 2024-05-01 Adrenomed Ag Anti-adrenomedullin (adm) antibody or anti-adm antibody fragment and pharmaceutical compostions comprising the same
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EP3511339B1 (de) 2012-02-20 2025-04-09 IPC Research, LLC An die menschliche komplementkomponente c5 bindende polypeptide
CN103308673B (zh) 2012-03-08 2017-05-31 思芬构技术有限公司 用于预测雌性对象中发生心血管事件的风险的方法
CN103308670B (zh) 2012-03-08 2017-06-09 思芬构技术有限公司 用于预测对象患糖尿病和/或代谢综合征的风险的方法
CN103308689B (zh) 2012-03-08 2017-04-12 思芬构技术有限公司 用于预测雌性对象中患上癌症的风险或诊断癌症的方法
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JP6440618B2 (ja) 2012-10-05 2018-12-19 アフィボディ・アーベー Ｈｅｒ３結合ポリペプチド
WO2014064238A1 (en) * 2012-10-25 2014-05-01 Affibody Ab Method for the separation of proteins containing an albumin-binding
CA2889037C (en) 2012-10-25 2021-06-22 Affibody Ab Abd binding polypeptide
JP6577868B2 (ja) * 2012-12-19 2019-09-18 アフィボディ・アーベー 新規ポリペプチド
ES2879023T3 (es) 2013-01-08 2021-11-19 Sphingotec Gmbh Niveles en ayunas de la hormona de crecimiento como marcador predictivo de riesgo cardiovascular
AU2014230018B2 (en) 2013-03-15 2018-02-22 Affibody Ab New polypeptides
SG11201507774YA (en) 2013-03-20 2015-10-29 Sphingotec Gmbh Adrenomedullin to guide therapy of blood pressure decline
MX367423B (es) 2013-08-28 2019-08-21 Affibody Ab Polipeptidos de union a c5.
BR112016003142A2 (pt) 2013-08-28 2017-10-17 Swedish Orphan Biovitrum Ab Publ ligação de polipeptídeos estáveis ao c5 do complemento humano
KR102399024B1 (ko) 2014-06-13 2022-05-17 애피바디 에이비 신규 폴리펩티드
US10633423B2 (en) 2014-06-13 2020-04-28 Affibody Ab IL-6-binding polypeptide complex
PL3193930T3 (pl) 2014-09-17 2019-12-31 Affibody Ab Nowe polipeptydy
EP3002589A1 (de) 2014-10-01 2016-04-06 sphingotec GmbH Verfahren zur stratifizierung einer frau zur hormonersatztherapie
EP3245224B1 (de) * 2015-01-12 2020-07-15 Affibody AB Il-17a-bindende polypeptide
CN107667294B (zh) 2015-04-24 2021-12-17 思芬构技术有限公司 用于预测慢性肾病发生风险的方法
US10364280B2 (en) 2015-10-30 2019-07-30 Affibody Ab Polypeptide
CN108290931A (zh) 2015-10-30 2018-07-17 阿菲博迪公司 对pd-l1具有亲和力的新的多肽
DE112017002105T5 (de) 2016-04-21 2019-04-25 Sphingotec Therapeutics Gmbh Verfahren zur Bestimmung von DPP3 und therapeutische Verfahren
EP3474887A1 (de) 2016-06-27 2019-05-01 AiCuris Anti-infective Cures GmbH Hcmv-eingangsinhibitoren
RU2019103403A (ru) 2016-07-08 2020-08-10 Сфинготек Гмбх Адреномедуллин для оценки застоя у индивидуума с острой сердечной недостаточностью
EP3309550A1 (de) 2016-10-12 2018-04-18 sphingotec GmbH Verfahren zum nachweis von apolipoprotein e4
EP3339324A1 (de) 2016-12-22 2018-06-27 sphingotec GmbH Anti-adrenomedullin (adm)-antikörper oder anti-adm antikörperfragment oder anti-adm-nicht-ig-gerüst zur verwendung in einer intervention und therapie von verstopfung bei einem darauf angewiesenen patienten
JP7727371B2 (ja) 2016-12-16 2025-08-21 アドレノメト アクチェンゲゼルシャフト うっ血の処置と治療を必要とする患者でその処置と治療に使用するための抗アドレノメデュリン（ＡＤＭ）抗体、または抗ＡＤＭ抗体フラグメント、または抗ＡＤＭ非Ｉｇ足場
UY37651A (es) 2017-03-31 2018-10-31 Swedish Orphan Biovitrum Ab Publ Polipéptido de unión al il-1r-i
EP3631459A1 (de) 2017-05-30 2020-04-08 SphingoTec GmbH Verfahren zur diagnose oder überwachung der nierenfunktion oder zur diagnose einer nierendysfunktion
WO2018219301A1 (zh) * 2017-05-31 2018-12-06 四川大学华西医院 一种PDGFRβ靶向性肿瘤坏死因子相关凋亡诱导配体变异体及其制备方法和用途
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WO2019077082A1 (en) 2017-10-18 2019-04-25 Adrenomed Ag SURVEILLANCE OF THERAPY UNDER TREATMENT WITH ANTI-ADRENOMEDULIN BINDER (ADM)
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CN119770645A (zh) 2018-02-08 2025-04-08 斯弗因高泰克有限公司 用于诊断和/或预测痴呆症的肾上腺髓质素和抗肾上腺髓质素结合物在治疗或预防痴呆症中的应用
EP3569614A1 (de) 2018-05-18 2019-11-20 Julius-Maximilians-Universität Würzburg Verbindungen und verfahren zur immobilisierung von myostatin-inhibitoren auf der extrazellulären matrix durch transglutaminase
EP3586865A1 (de) 2018-06-21 2020-01-01 Charité - Universitätsmedizin Berlin Ergänzende anaphylatoxinbindemittel und deren verwendung in der behandlung einer person mit okularer wunde und/oder fibrose
BR112021010069A2 (pt) 2018-12-20 2021-11-23 Sphingotec Gmbh Selenoproteína p em insuficiência cardíaca
CN113557031A (zh) 2018-12-21 2021-10-26 4Teen4制药有限公司 使用血管紧张肽受体激动剂和/或其前体的治疗的疗法指导和/或疗法监测
AU2020328194A1 (en) 2019-08-15 2022-03-17 Sphingotec Gmbh A method for diagnosing or monitoring kidney function or diagnosing kidney dysfunction in pediatric patients
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EP4687942A1 (de) 2023-03-29 2026-02-11 4TEEN4 Pharmaceuticals GmbH Dpp3-hemmer für herzmuskelschutz und prävention von myokardläsionen bei kritisch kranken patienten mit blutdruckabfall
WO2024213587A1 (en) 2023-04-11 2024-10-17 Antaros Tracer Ab Drug delivery systems
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WO2025229075A1 (en) 2024-05-03 2025-11-06 Sphingotec Gmbh A method for the specific determination of proenkephalin fragment 119-159
WO2025248139A1 (en) 2024-05-31 2025-12-04 4TEEN4 Pharmaceuticals GmbH Use of adrenomedullin or fragments thereof in the treatment of a patient in need thereof
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WO2026046968A1 (en) 2024-08-26 2026-03-05 4TEEN4 Pharmaceuticals GmbH Dpp3 binders for the treatment of endothelial dysfunction
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Family Cites Families (2)

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Also Published As

Publication number Publication date
WO2009077175A1 (en) 2009-06-25
DK2231860T3 (da) 2011-12-05
EP2231860A1 (de) 2010-09-29
EP2231860B1 (de) 2011-10-05
ES2373832T3 (es) 2012-02-09

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