ATE529184T1 - Verfahren zur steuerung des verlaufs einer flüssigkeit in einer mikrofluidischen einheit - Google Patents
Verfahren zur steuerung des verlaufs einer flüssigkeit in einer mikrofluidischen einheitInfo
- Publication number
- ATE529184T1 ATE529184T1 AT07730986T AT07730986T ATE529184T1 AT E529184 T1 ATE529184 T1 AT E529184T1 AT 07730986 T AT07730986 T AT 07730986T AT 07730986 T AT07730986 T AT 07730986T AT E529184 T1 ATE529184 T1 AT E529184T1
- Authority
- AT
- Austria
- Prior art keywords
- controlling
- microchannels
- pressure difference
- course
- liquid
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00286—Reactor vessels with top and bottom openings
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00418—Means for dispensing and evacuation of reagents using pressure
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/0059—Sequential processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00686—Automatic
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- B01J2219/00698—Measurement and control of process parameters
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00702—Processes involving means for analysing and characterising the products
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00718—Type of compounds synthesised
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- B01J2219/00718—Type of compounds synthesised
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00851—Additional features
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00858—Aspects relating to the size of the reactor
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- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
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- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01L2300/16—Surface properties and coatings
- B01L2300/161—Control and use of surface tension forces, e.g. hydrophobic, hydrophilic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/0318—Processes
- Y10T137/0396—Involving pressure control
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/206—Flow affected by fluid contact, energy field or coanda effect [e.g., pure fluid device or system]
- Y10T137/2224—Structure of body of device
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/87265—Dividing into parallel flow paths with recombining
- Y10T137/87298—Having digital flow controller
- Y10T137/87306—Having plural branches under common control for separate valve actuators
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/87265—Dividing into parallel flow paths with recombining
- Y10T137/87499—Fluid actuated or retarded
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Organic Chemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0601375A FR2897282B1 (fr) | 2006-02-16 | 2006-02-16 | Procede de controle de l'avancee d'un liquide dans un compos ant microfluidique |
| PCT/FR2007/000275 WO2007093712A1 (fr) | 2006-02-16 | 2007-02-15 | Procede de controle de l'avancee d'un liquide dans un composant microfluidique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE529184T1 true ATE529184T1 (de) | 2011-11-15 |
Family
ID=37056531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07730986T ATE529184T1 (de) | 2006-02-16 | 2007-02-15 | Verfahren zur steuerung des verlaufs einer flüssigkeit in einer mikrofluidischen einheit |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8215338B2 (de) |
| EP (1) | EP1984110B1 (de) |
| JP (1) | JP5031776B2 (de) |
| CN (1) | CN101384354B (de) |
| AT (1) | ATE529184T1 (de) |
| FR (1) | FR2897282B1 (de) |
| WO (1) | WO2007093712A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007049534A1 (ja) * | 2005-10-28 | 2007-05-03 | Arkray, Inc. | 送液方法、およびこれに用いるカートリッジ |
| WO2008113112A1 (en) * | 2007-03-16 | 2008-09-25 | Cleveland Biosensors Pty Ltd | Stop structure for microfluidic device |
| AU2009302464B2 (en) * | 2008-10-10 | 2014-07-03 | Cytyc Corporation | Microfluidic apparatus and method for preparing cytological specimens |
| FR2938063B1 (fr) * | 2008-11-05 | 2014-09-19 | Commissariat Energie Atomique | Dispositif de preparation et/ou de traitement d'un echantillon biologique |
| GB0912509D0 (en) * | 2009-07-17 | 2009-08-26 | Norchip As | A microfabricated device for metering an analyte |
| CN102527306B (zh) * | 2010-12-28 | 2014-01-29 | 中国科学院化学研究所 | 一种阵列式连续流动微流控芯片装置及其制作方法与应用 |
| WO2013037284A1 (en) * | 2011-09-15 | 2013-03-21 | The Chinese University Of Hong Kong | Microfluidic platform and method for controlling the same |
| EP2896457B1 (de) * | 2014-01-15 | 2017-08-23 | IMEC vzw | Mikrostrukturierte Mikrostützen-Arrays zur steuerbaren Befüllung einer kapillaren Pumpe |
| CA2966415C (en) * | 2014-10-31 | 2023-03-28 | University Of Iowa Research Foundation | Fluid handling systems for application of fluid shear stress to a fluid sample |
| US12290811B2 (en) | 2015-01-23 | 2025-05-06 | Unchained Labs | Microfluidic serial dilution platform based well-plate using an oil-free immiscible phase driven by manual or electronic pipettors |
| FR3035009B1 (fr) | 2015-04-20 | 2020-02-07 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Dispositif microfluidique de controle d'ecoulement d'un fluide |
| WO2017001436A1 (en) * | 2015-06-29 | 2017-01-05 | Imec Vzw | Valve-less mixing method and mixing device |
| FR3064621B1 (fr) * | 2017-04-03 | 2022-02-18 | Fluigent | Dispositif microfluidique |
| WO2018200896A1 (en) | 2017-04-28 | 2018-11-01 | Neofluidics, Llc | Fluidic devices with reaction wells and uses thereof |
| CA3072328A1 (en) | 2017-08-09 | 2019-02-14 | Neofluidics, Llc | Devices and methods for bioassay |
| CN108051598B (zh) * | 2017-10-19 | 2020-01-24 | 广州市第一人民医院 | 一种可预装载试剂的即用型液滴生物分析芯片及其应用 |
| EP3706905A4 (de) | 2017-11-10 | 2021-11-03 | Neofluidics, LLC | Integrierte fluidische schaltung und vorrichtung zur tröpfchenmanipulation und verfahren dafür |
| EP3787795B1 (de) * | 2018-04-30 | 2024-10-30 | Protein Fluidics, Inc. | Ventilloser fluidischer schalt-flowchip und verwendungen davon |
| EP3870369A4 (de) * | 2018-10-26 | 2022-11-09 | Neofluidics, LLC | Fluidische vorrichtungen mit reaktionsmulden und verengungskanälen und verwendungen davon |
| FR3116215B1 (fr) * | 2020-11-17 | 2024-03-29 | Magia Diagnostics | Cartouche comportant une pluralite de chambres d’analyse pour recevoir un liquide biologique |
| EP4089161A1 (de) * | 2021-05-12 | 2022-11-16 | ibidi GmbH | Substrat zur untersuchung von proben und system umfassend das substrat |
| CN113952892B (zh) * | 2021-12-03 | 2023-10-10 | 花安堂生物科技集团有限公司 | 一种利用负压制备悬浮微液滴的方法 |
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| US4390885A (en) * | 1981-06-26 | 1983-06-28 | Texas Instruments Incorporated | Apparatus and method for fluid transfer |
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| DE10022398B4 (de) * | 2000-04-28 | 2011-03-17 | Eppendorf Ag | Gaspolster-Mikrodosiersystem |
| SE0004351D0 (sv) * | 2000-11-27 | 2000-11-27 | Helen Andersson | System och metod för tidstyrd vätskehantering för reaktioner och processer i ett mikrofluidiskt flödescellsystem |
| WO2002068821A2 (en) * | 2001-02-28 | 2002-09-06 | Lightwave Microsystems Corporation | Microfluidic control using dieletric pumping |
| US7041068B2 (en) * | 2001-06-12 | 2006-05-09 | Pelikan Technologies, Inc. | Sampling module device and method |
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| NO20023398D0 (no) * | 2002-07-15 | 2002-07-15 | Osmotex As | Anordning og fremgangsmåte for transport av v¶ske gjennom materialer |
| JP4701758B2 (ja) * | 2005-03-10 | 2011-06-15 | 凸版印刷株式会社 | マイクロチャネルチップ |
-
2006
- 2006-02-16 FR FR0601375A patent/FR2897282B1/fr not_active Expired - Fee Related
-
2007
- 2007-02-15 AT AT07730986T patent/ATE529184T1/de not_active IP Right Cessation
- 2007-02-15 EP EP20070730986 patent/EP1984110B1/de not_active Not-in-force
- 2007-02-15 WO PCT/FR2007/000275 patent/WO2007093712A1/fr not_active Ceased
- 2007-02-15 JP JP2008554814A patent/JP5031776B2/ja not_active Expired - Fee Related
- 2007-02-15 US US12/223,059 patent/US8215338B2/en not_active Expired - Fee Related
- 2007-02-15 CN CN2007800058532A patent/CN101384354B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1984110A1 (de) | 2008-10-29 |
| CN101384354B (zh) | 2013-09-18 |
| US8215338B2 (en) | 2012-07-10 |
| EP1984110B1 (de) | 2011-10-19 |
| WO2007093712A1 (fr) | 2007-08-23 |
| FR2897282A1 (fr) | 2007-08-17 |
| FR2897282B1 (fr) | 2008-05-30 |
| JP5031776B2 (ja) | 2012-09-26 |
| JP2009526642A (ja) | 2009-07-23 |
| CN101384354A (zh) | 2009-03-11 |
| US20080314454A1 (en) | 2008-12-25 |
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