ATE529747T1 - Verfahren zur bestimmung der transportaktivität eines transportproteins - Google Patents

Verfahren zur bestimmung der transportaktivität eines transportproteins

Info

Publication number
ATE529747T1
ATE529747T1 AT07802629T AT07802629T ATE529747T1 AT E529747 T1 ATE529747 T1 AT E529747T1 AT 07802629 T AT07802629 T AT 07802629T AT 07802629 T AT07802629 T AT 07802629T AT E529747 T1 ATE529747 T1 AT E529747T1
Authority
AT
Austria
Prior art keywords
transport
determining
activity
protein
transport activity
Prior art date
Application number
AT07802629T
Other languages
English (en)
Inventor
Yunhai Cui
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Application granted granted Critical
Publication of ATE529747T1 publication Critical patent/ATE529747T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/44—Multiple drug resistance

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT07802629T 2006-08-25 2007-08-15 Verfahren zur bestimmung der transportaktivität eines transportproteins ATE529747T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06119511A EP1892530A1 (de) 2006-08-25 2006-08-25 Verfahren zur Bestimmung der Transportaktivität eines Transportproteins
PCT/EP2007/058473 WO2008022956A1 (en) 2006-08-25 2007-08-15 Method for determining transport activity of a transport protein

Publications (1)

Publication Number Publication Date
ATE529747T1 true ATE529747T1 (de) 2011-11-15

Family

ID=37996584

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07802629T ATE529747T1 (de) 2006-08-25 2007-08-15 Verfahren zur bestimmung der transportaktivität eines transportproteins

Country Status (8)

Country Link
US (1) US20100015727A1 (de)
EP (2) EP1892530A1 (de)
JP (1) JP5161219B2 (de)
AT (1) ATE529747T1 (de)
CA (1) CA2660512A1 (de)
DK (1) DK2064548T3 (de)
ES (1) ES2372317T3 (de)
WO (1) WO2008022956A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010052337A2 (en) * 2008-11-10 2010-05-14 Ecole Polytechnique Federale De Lausanne (Epfl) Bioanalytical procedure to detect membrane receptor activation
KR20140073215A (ko) * 2012-12-06 2014-06-16 삼성전자주식회사 세포 분리용 조성물, 키트 및 이를 이용한 세포 분리 방법
WO2014200816A1 (en) 2013-06-14 2014-12-18 Biotranex, Llc Method for measuring bile salt export transport and/or formation activity
WO2016167953A1 (en) 2015-04-16 2016-10-20 Biotranex, Llc Method of measuring inhibition of phosphatidylcholine export transport and/or formation activity
CN110105368B (zh) * 2019-05-09 2022-01-07 上海大学 去氧紫杉烷类似物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6247555A (ja) * 1985-08-23 1987-03-02 エフ．ホフマン　―　ラ　ロシュ　アーゲー シンチレ−シヨン近接定量法
WO1997010502A1 (en) * 1995-09-15 1997-03-20 Merck & Co., Inc. A high throughput assay using fusion proteins
DE60035163T2 (de) * 1999-03-15 2008-02-21 University Of British Columbia, Vancouver Abc1 polypeptide und verfahren und reagenzien zur modulation des cholesterolgehalts
GB9922352D0 (en) * 1999-09-21 1999-11-24 Avidex Ltd Screening method
GB2383329A (en) * 2000-08-18 2003-06-25 Sense Proteomic Ltd Lipo-or amphiphilic scintillators and their use in assays
JP2004537265A (ja) * 2000-12-15 2004-12-16 ファルマシア・アンド・アップジョン・カンパニー オキサゾリジノンフォトアフィニティープローブ、その使用および化合物
US20040072746A1 (en) * 2001-10-16 2004-04-15 Michael Sullivan Inhibitors of monocarboxylate transport
EP1697744A1 (de) * 2003-11-21 2006-09-06 AstraZeneca AB Screeningverfahren
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
JP2006197832A (ja) * 2005-01-19 2006-08-03 Tohoku Univ 環境感受性蛍光プローブを用いたシステイン残基が変異導入されたａｂｃトランスポーターの汎用的な基質親和性検出方法

Also Published As

Publication number Publication date
EP2064548B1 (de) 2011-10-19
US20100015727A1 (en) 2010-01-21
DK2064548T3 (da) 2012-02-06
JP5161219B2 (ja) 2013-03-13
EP1892530A1 (de) 2008-02-27
EP2064548A1 (de) 2009-06-03
JP2010501837A (ja) 2010-01-21
WO2008022956A1 (en) 2008-02-28
ES2372317T3 (es) 2012-01-18
CA2660512A1 (en) 2008-02-28

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