ATE530574T1 - Für ein utrophintranskriptionsspezifisches regulatorprotein kodierende nukleinsäure, damit kodiertes protein und verwendung - Google Patents
Für ein utrophintranskriptionsspezifisches regulatorprotein kodierende nukleinsäure, damit kodiertes protein und verwendungInfo
- Publication number
- ATE530574T1 ATE530574T1 AT08807901T AT08807901T ATE530574T1 AT E530574 T1 ATE530574 T1 AT E530574T1 AT 08807901 T AT08807901 T AT 08807901T AT 08807901 T AT08807901 T AT 08807901T AT E530574 T1 ATE530574 T1 AT E530574T1
- Authority
- AT
- Austria
- Prior art keywords
- protein
- nucleic acid
- acid coding
- transcription
- utrophin
- Prior art date
Links
- 108010075653 Utrophin Proteins 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000011856 Utrophin Human genes 0.000 title 1
- 102000034356 gene-regulatory proteins Human genes 0.000 title 1
- 108091006104 gene-regulatory proteins Proteins 0.000 title 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 239000011701 zinc Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4707—Muscular dystrophy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Air Bags (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000523A ITRM20070523A1 (it) | 2007-10-05 | 2007-10-05 | Acido nucleico codificante per una proteina regolatrice specifica della trascrizione dell'utrofina proteina da esso codificata e sue applicazioni |
| PCT/IB2008/054089 WO2009044383A1 (en) | 2007-10-05 | 2008-10-06 | Nucleic acid codifying for a utrophin transcription specific regulating protein, protein codified thereby and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE530574T1 true ATE530574T1 (de) | 2011-11-15 |
Family
ID=40202864
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08807901T ATE530574T1 (de) | 2007-10-05 | 2008-10-06 | Für ein utrophintranskriptionsspezifisches regulatorprotein kodierende nukleinsäure, damit kodiertes protein und verwendung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8304235B2 (de) |
| EP (1) | EP2193200B1 (de) |
| AT (1) | ATE530574T1 (de) |
| ES (1) | ES2360916T3 (de) |
| IT (1) | ITRM20070523A1 (de) |
| WO (1) | WO2009044383A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
| KR20150030205A (ko) | 2012-05-16 | 2015-03-19 | 라나 테라퓨틱스, 인크. | Smn 유전자 패밀리 발현을 조절하기 위한 조성물 및 방법 |
| AU2013262709A1 (en) | 2012-05-16 | 2015-01-22 | Rana Therapeutics, Inc. | Compositions and methods for modulating MECP2 expression |
| SG11201407486PA (en) * | 2012-05-16 | 2014-12-30 | Rana Therapeutics Inc | Compositions and methods for modulating utrn expression |
| ITTO20130669A1 (it) | 2013-08-05 | 2015-02-06 | Consiglio Nazionale Ricerche | Vettore adeno-associato ricombinante muscolo-specifico e suo impiego nel trattamento di patologie muscolari |
| US10301367B2 (en) * | 2014-07-26 | 2019-05-28 | Consiglio Nazionale Delle Ricerche | Compositions and methods for treatment of muscular dystrophy |
| JP7401432B2 (ja) | 2017-12-01 | 2023-12-19 | エンコーデッド セラピューティクス， インコーポレイテッド | 操作されたｄｎａ結合タンパク質 |
| CA3119618A1 (en) | 2018-11-16 | 2020-05-22 | Astellas Pharma Inc. | Method for treating muscular dystrophy by targeting utrophin gene |
| WO2020243651A1 (en) | 2019-05-29 | 2020-12-03 | Encoded Therapeutics, Inc. | Compositions and methods for selective gene regulation |
| WO2021230385A1 (en) | 2020-05-15 | 2021-11-18 | Astellas Pharma Inc. | Method for treating muscular dystrophy by targeting utrophin gene |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6242568B1 (en) * | 1994-01-18 | 2001-06-05 | The Scripps Research Institute | Zinc finger protein derivatives and methods therefor |
-
2007
- 2007-10-05 IT IT000523A patent/ITRM20070523A1/it unknown
-
2008
- 2008-09-30 ES ES08804901T patent/ES2360916T3/es active Active
- 2008-10-06 US US12/680,681 patent/US8304235B2/en not_active Expired - Fee Related
- 2008-10-06 EP EP08807901A patent/EP2193200B1/de not_active Not-in-force
- 2008-10-06 AT AT08807901T patent/ATE530574T1/de not_active IP Right Cessation
- 2008-10-06 WO PCT/IB2008/054089 patent/WO2009044383A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009044383A1 (en) | 2009-04-09 |
| EP2193200A1 (de) | 2010-06-09 |
| ES2360916T3 (es) | 2011-06-10 |
| WO2009044383A8 (en) | 2009-10-01 |
| US20100216712A1 (en) | 2010-08-26 |
| ITRM20070523A1 (it) | 2009-04-06 |
| EP2193200B1 (de) | 2011-10-26 |
| US8304235B2 (en) | 2012-11-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |