ATE530672T1 - Rekombinante adenoviren mit affen-adenovirus proteinen und verwendung davon. - Google Patents
Rekombinante adenoviren mit affen-adenovirus proteinen und verwendung davon.Info
- Publication number
- ATE530672T1 ATE530672T1 AT02756264T AT02756264T ATE530672T1 AT E530672 T1 ATE530672 T1 AT E530672T1 AT 02756264 T AT02756264 T AT 02756264T AT 02756264 T AT02756264 T AT 02756264T AT E530672 T1 ATE530672 T1 AT E530672T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- recombinant adenoviruses
- adenovirus proteins
- monkey adenovirus
- monkey
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 4
- 241000701161 unidentified adenovirus Species 0.000 title abstract 2
- 241000282693 Cercopithecidae Species 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 241000282577 Pan troglodytes Species 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30050101P | 2001-06-22 | 2001-06-22 | |
| US38563202P | 2002-06-04 | 2002-06-04 | |
| PCT/US2002/019735 WO2003000851A2 (en) | 2001-06-22 | 2002-06-20 | Method for rapid screening of bacterial transformants and novel simian adenovirus proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE530672T1 true ATE530672T1 (de) | 2011-11-15 |
Family
ID=26971814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02756264T ATE530672T1 (de) | 2001-06-22 | 2002-06-20 | Rekombinante adenoviren mit affen-adenovirus proteinen und verwendung davon. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7344872B2 (de) |
| EP (1) | EP1409748B1 (de) |
| JP (1) | JP4399255B2 (de) |
| AT (1) | ATE530672T1 (de) |
| AU (1) | AU2002322285A1 (de) |
| CA (1) | CA2450470C (de) |
| ES (1) | ES2375557T3 (de) |
| WO (1) | WO2003000851A2 (de) |
Families Citing this family (85)
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|---|---|---|---|---|
| DE3928858A1 (de) * | 1989-08-31 | 1991-03-07 | Beiersdorf Ag | Vernetzte hydrogele und verfahren zu deren herstellung |
| US20040136963A1 (en) * | 2001-06-22 | 2004-07-15 | The Trustees Of The University Of Pennsylvania | Simian adenovirus vectors and methods of use |
| AU2002322285A1 (en) | 2001-06-22 | 2003-01-08 | The Trustees Of The University Of Pennsylvania | Method for rapid screening of bacterial transformants and novel simian adenovirus proteins |
| HU230364B1 (hu) | 2001-11-21 | 2016-03-29 | The Trustees Of The University Of Pennsylvania | Simian adenovírus nukleinsav és aminosav-szekvencia, azt tartalmazó vektorok, és eljárások annak alkalmazására |
| US7491508B2 (en) * | 2003-06-20 | 2009-02-17 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| US7291498B2 (en) * | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| SI2163260T1 (sl) | 2004-01-23 | 2017-07-31 | Msd Italia S.R.L. | Nosilci šimpanzjih adenovirusnih cepiv |
| AU2011247887B2 (en) * | 2004-01-23 | 2014-11-20 | Msd Italia S.R.L. | Chimpanzee adenovirus vaccine carriers |
| EP1773303A2 (de) * | 2004-05-25 | 2007-04-18 | Chimeracore, Inc. | Selbstmontierendes nanopartikel-wirkstofffreisetzungssystem |
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| NZ581306A (en) | 2004-11-16 | 2011-03-31 | Crucell Holland Bv | Multivalent vaccines comprising recombinant viral vectors |
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| WO2009105084A2 (en) * | 2007-11-28 | 2009-08-27 | The Trustees Of The University Of Pennsylvania | Simian subfamily c adenoviruses sadv-40, -31, and-34 and uses thereof |
| PT2220242T (pt) | 2007-11-28 | 2017-04-03 | Univ Pennsylvania | Adenovírus símio da subfamília b sadv-28,27,-29,-32,-33 e -35 e suas utilizações |
| KR101761691B1 (ko) * | 2007-11-28 | 2017-07-26 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 유인원 ｅ 아데노바이러스 ｓａｄｖ-39, -25.2, -26, -30, -37, 및 -38 |
| EP2250255A2 (de) | 2008-03-04 | 2010-11-17 | The Trustees of the University of Pennsylvania | Simian-adenoviren sadv-36, -42.1, -42.2 und -44 sowie anwendungen davon |
| US9217155B2 (en) | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
| US8940290B2 (en) * | 2008-10-31 | 2015-01-27 | The Trustees Of The University Of Pennsylvania | Simian adenoviruses SAdV-43, -45, -46, -47, -48, -49, and -50 and uses thereof |
| CA2749325C (en) | 2009-02-02 | 2021-03-30 | Okairos Ag | Simian adenovirus nucleic acid- and amino acid-sequences, vectors containing same, and uses thereof |
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| WO2010138263A2 (en) | 2009-05-28 | 2010-12-02 | University Of Massachusetts | Novel aav 's and uses thereof |
| WO2010138675A1 (en) | 2009-05-29 | 2010-12-02 | The Trustees Of The University Of Pennsylvania | Simian adenovirus 41 and uses thereof |
| CA2833905C (en) | 2010-04-23 | 2019-09-10 | University Of Massachusetts | Multicistronic expression constructs |
| EP3567106A1 (de) | 2010-04-23 | 2019-11-13 | University of Massachusetts | Auf das zns abzielende aav-vektoren und verfahren zur verwendung davon |
| US9272053B2 (en) | 2010-04-23 | 2016-03-01 | University Of Massachusetts | AAV-based treatment of cholesterol-related disorders |
| CN103118702A (zh) | 2010-09-20 | 2013-05-22 | 克鲁塞尔荷兰公司 | 活动性结核病的治疗性接种 |
| AU2011332025B2 (en) | 2010-11-23 | 2015-06-25 | The Trustees Of The University Of Pennsylvania | Subfamily E simian adenoviruses A1321, A1325, A1295, A1309 and A1322 and uses thereof |
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| SG10201609511XA (en) | 2012-05-18 | 2016-12-29 | Univ Pennsylvania | Subfamily e simian adenoviruses a1302, a1320, a1331 and a1337 and uses thereof |
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| WO2019135816A2 (en) | 2017-10-23 | 2019-07-11 | The Broad Institute, Inc. | Novel nucleic acid modifiers |
| EP3710039A4 (de) | 2017-11-13 | 2021-08-04 | The Broad Institute, Inc. | Verfahren und zusammensetzungen zur behandlung von krebs durch targeting des clec2d-klrb1-wegs |
| JP7653013B2 (ja) | 2018-01-04 | 2025-03-28 | アイコニック セラピューティクス リミテッド ライアビリティ カンパニー | 抗組織因子抗体、抗体薬物コンジュゲート、及び関連する方法 |
| JP7430395B2 (ja) | 2018-04-09 | 2024-02-13 | ソーク インスティテュート フォー バイオロジカル スタディーズ | 複製特質が増強された腫瘍溶解性アデノウイルス組成物 |
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| AU2019406778A1 (en) | 2018-12-17 | 2021-07-22 | Massachusetts Institute Of Technology | Crispr-associated transposase systems and methods of use thereof |
| CN113924115A (zh) | 2019-01-31 | 2022-01-11 | 俄勒冈健康与科学大学 | 用于aav衣壳的使用转录依赖性定向进化的方法 |
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Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770442A (en) | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| WO1998010087A1 (en) | 1996-09-06 | 1998-03-12 | Trustees Of The University Of Pennsylvania | Chimpanzee adenovirus vectors |
| US5922315A (en) | 1997-01-24 | 1999-07-13 | Genetic Therapy, Inc. | Adenoviruses having altered hexon proteins |
| ATE342350T1 (de) | 1998-02-17 | 2006-11-15 | Uab Research Foundation | Modifizierte adenoviren welche ein faserersatzprotein enthalten |
| US20030017138A1 (en) * | 1998-07-08 | 2003-01-23 | Menzo Havenga | Chimeric adenoviruses |
| AU2002322285A1 (en) | 2001-06-22 | 2003-01-08 | The Trustees Of The University Of Pennsylvania | Method for rapid screening of bacterial transformants and novel simian adenovirus proteins |
| US20030092161A1 (en) | 2001-09-19 | 2003-05-15 | The Trustees Of The University Of Pennsylvania | Compositions and methods for production of recombinant viruses, and uses therefor |
| HU230364B1 (hu) | 2001-11-21 | 2016-03-29 | The Trustees Of The University Of Pennsylvania | Simian adenovírus nukleinsav és aminosav-szekvencia, azt tartalmazó vektorok, és eljárások annak alkalmazására |
| US7291498B2 (en) * | 2003-06-20 | 2007-11-06 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| US7491508B2 (en) * | 2003-06-20 | 2009-02-17 | The Trustees Of The University Of Pennsylvania | Methods of generating chimeric adenoviruses and uses for such chimeric adenoviruses |
| FR2860004A1 (fr) | 2003-09-18 | 2005-03-25 | Roussy Inst Gustave | Nouveau vecteur adenoviral pour l'infection de cellules deficientes ou depourvues en recepteurs car |
| EP2012822B1 (de) * | 2006-04-28 | 2010-01-20 | The Trustees of the University of Pennsylvania | Modifiziertes adenovirus-hexon-protein und anwendungen davon |
-
2002
- 2002-06-20 AU AU2002322285A patent/AU2002322285A1/en not_active Abandoned
- 2002-06-20 AT AT02756264T patent/ATE530672T1/de not_active IP Right Cessation
- 2002-06-20 CA CA2450470A patent/CA2450470C/en not_active Expired - Fee Related
- 2002-06-20 WO PCT/US2002/019735 patent/WO2003000851A2/en not_active Ceased
- 2002-06-20 EP EP02756264A patent/EP1409748B1/de not_active Expired - Lifetime
- 2002-06-20 JP JP2003507238A patent/JP4399255B2/ja not_active Expired - Fee Related
- 2002-06-20 US US10/477,527 patent/US7344872B2/en not_active Expired - Lifetime
- 2002-06-20 ES ES02756264T patent/ES2375557T3/es not_active Expired - Lifetime
-
2008
- 2008-01-25 US US12/011,377 patent/US7838277B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2450470A1 (en) | 2003-01-03 |
| WO2003000851A2 (en) | 2003-01-03 |
| US20080219954A1 (en) | 2008-09-11 |
| WO2003000851A3 (en) | 2003-02-20 |
| US20040171807A1 (en) | 2004-09-02 |
| ES2375557T3 (es) | 2012-03-02 |
| EP1409748A4 (de) | 2005-03-30 |
| JP2004537300A (ja) | 2004-12-16 |
| US7344872B2 (en) | 2008-03-18 |
| US7838277B2 (en) | 2010-11-23 |
| CA2450470C (en) | 2012-08-28 |
| EP1409748A2 (de) | 2004-04-21 |
| EP1409748B1 (de) | 2011-10-26 |
| JP4399255B2 (ja) | 2010-01-13 |
| AU2002322285A1 (en) | 2003-01-08 |
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