ATE532856T1 - Modifizierte polymerasen des typs b zum verbesserten einbau von nukleotidanaloga - Google Patents

Modifizierte polymerasen des typs b zum verbesserten einbau von nukleotidanaloga

Info

Publication number
ATE532856T1
ATE532856T1 AT04768438T AT04768438T ATE532856T1 AT E532856 T1 ATE532856 T1 AT E532856T1 AT 04768438 T AT04768438 T AT 04768438T AT 04768438 T AT04768438 T AT 04768438T AT E532856 T1 ATE532856 T1 AT E532856T1
Authority
AT
Austria
Prior art keywords
polymerases
nucleotide analogs
improved incorporation
modified type
incorporation
Prior art date
Application number
AT04768438T
Other languages
English (en)
Inventor
Geoffrey Paul Smith
David Mark Dunstan Bailey
Raquel Maria Sanches
Harold Swerdlow
David James Earnshaw
Original Assignee
Illumina Cambridge Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29226911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE532856(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Illumina Cambridge Ltd filed Critical Illumina Cambridge Ltd
Application granted granted Critical
Publication of ATE532856T1 publication Critical patent/ATE532856T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/07—Nucleotidyltransferases (2.7.7)
    • C12Y207/07007—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT04768438T 2003-09-11 2004-09-10 Modifizierte polymerasen des typs b zum verbesserten einbau von nukleotidanaloga ATE532856T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0321306.3A GB0321306D0 (en) 2003-09-11 2003-09-11 Modified polymerases for improved incorporation of nucleotide analogues
PCT/GB2004/003891 WO2005024010A1 (en) 2003-09-11 2004-09-10 Modified polymerases for improved incorporation of nucleotide analogues

Publications (1)

Publication Number Publication Date
ATE532856T1 true ATE532856T1 (de) 2011-11-15

Family

ID=29226911

Family Applications (2)

Application Number Title Priority Date Filing Date
AT10180445T ATE557084T1 (de) 2003-09-11 2004-09-10 Modifizierte dna-polymerasen zur verbesserten inkorporation von nukleotidanaloga
AT04768438T ATE532856T1 (de) 2003-09-11 2004-09-10 Modifizierte polymerasen des typs b zum verbesserten einbau von nukleotidanaloga

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT10180445T ATE557084T1 (de) 2003-09-11 2004-09-10 Modifizierte dna-polymerasen zur verbesserten inkorporation von nukleotidanaloga

Country Status (7)

Country Link
US (7) US8460910B2 (de)
EP (2) EP1664287B1 (de)
JP (1) JP5706057B2 (de)
AT (2) ATE557084T1 (de)
DK (1) DK2325304T3 (de)
GB (1) GB0321306D0 (de)
WO (1) WO2005024010A1 (de)

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