|
US6261808B1
(en)
*
|
1992-08-04 |
2001-07-17 |
Replicon, Inc. |
Amplification of nucleic acid molecules via circular replicons
|
|
WO1994003624A1
(en)
*
|
1992-08-04 |
1994-02-17 |
Auerbach Jeffrey I |
Methods for the isothermal amplification of nucleic acid molecules
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
WO2000061498A2
(en)
|
1999-04-13 |
2000-10-19 |
Semitool, Inc. |
System for electrochemically processing a workpiece
|
|
US6893868B2
(en)
|
1997-02-20 |
2005-05-17 |
Onco Immunin, Inc. |
Homo-doubly labeled compositions for the detection of enzyme activity in biological samples
|
|
US7312302B2
(en)
|
1997-02-20 |
2007-12-25 |
Oncolmmunin, Inc. |
Compositions for the detection of enzyme activity in biological samples and methods of use thereof
|
|
US6037137A
(en)
|
1997-02-20 |
2000-03-14 |
Oncoimmunin, Inc. |
Fluorogenic peptides for the detection of protease activity
|
|
US6565729B2
(en)
|
1998-03-20 |
2003-05-20 |
Semitool, Inc. |
Method for electrochemically depositing metal on a semiconductor workpiece
|
|
TWI223678B
(en)
*
|
1998-03-20 |
2004-11-11 |
Semitool Inc |
Process for applying a metal structure to a workpiece, the treated workpiece and a solution for electroplating copper
|
|
US6497801B1
(en)
*
|
1998-07-10 |
2002-12-24 |
Semitool Inc |
Electroplating apparatus with segmented anode array
|
|
US20040106110A1
(en)
*
|
1998-07-30 |
2004-06-03 |
Solexa, Ltd. |
Preparation of polynucleotide arrays
|
|
US20100130368A1
(en)
*
|
1998-07-30 |
2010-05-27 |
Shankar Balasubramanian |
Method and system for sequencing polynucleotides
|
|
US7020537B2
(en)
|
1999-04-13 |
2006-03-28 |
Semitool, Inc. |
Tuning electrodes used in a reactor for electrochemically processing a microelectronic workpiece
|
|
US7585398B2
(en)
|
1999-04-13 |
2009-09-08 |
Semitool, Inc. |
Chambers, systems, and methods for electrochemically processing microfeature workpieces
|
|
US7160421B2
(en)
*
|
1999-04-13 |
2007-01-09 |
Semitool, Inc. |
Turning electrodes used in a reactor for electrochemically processing a microelectronic workpiece
|
|
US7264698B2
(en)
|
1999-04-13 |
2007-09-04 |
Semitool, Inc. |
Apparatus and methods for electrochemical processing of microelectronic workpieces
|
|
US7189318B2
(en)
*
|
1999-04-13 |
2007-03-13 |
Semitool, Inc. |
Tuning electrodes used in a reactor for electrochemically processing a microelectronic workpiece
|
|
US6368475B1
(en)
*
|
2000-03-21 |
2002-04-09 |
Semitool, Inc. |
Apparatus for electrochemically processing a microelectronic workpiece
|
|
US7351314B2
(en)
|
2003-12-05 |
2008-04-01 |
Semitool, Inc. |
Chambers, systems, and methods for electrochemically processing microfeature workpieces
|
|
US7438788B2
(en)
|
1999-04-13 |
2008-10-21 |
Semitool, Inc. |
Apparatus and methods for electrochemical processing of microelectronic workpieces
|
|
US7351315B2
(en)
|
2003-12-05 |
2008-04-01 |
Semitool, Inc. |
Chambers, systems, and methods for electrochemically processing microfeature workpieces
|
|
US6916412B2
(en)
|
1999-04-13 |
2005-07-12 |
Semitool, Inc. |
Adaptable electrochemical processing chamber
|
|
JP2003510017A
(ja)
|
1999-06-22 |
2003-03-18 |
インビトロジェン コーポレイション |
核酸の検出および識別のために改良されたプライマーおよび方法
|
|
US6692915B1
(en)
*
|
1999-07-22 |
2004-02-17 |
Girish N. Nallur |
Sequencing a polynucleotide on a generic chip
|
|
JP4721603B2
(ja)
*
|
1999-11-08 |
2011-07-13 |
栄研化学株式会社 |
変異および/または多型の検出方法
|
|
WO2001034838A1
(en)
*
|
1999-11-08 |
2001-05-17 |
Eiken Kagaku Kabushiki Kaisha |
Method of detecting variation or polymorphism
|
|
US6664081B2
(en)
*
|
1999-12-17 |
2003-12-16 |
Gen-Probe Incorporated |
Nucleic acid amplification and detection of mycobacterium species
|
|
US7205129B1
(en)
|
2000-02-28 |
2007-04-17 |
Qiagen Gmbh |
Method for reducing artifacts in nucleic acid amplification
|
|
ES2317893T3
(es)
*
|
2000-03-31 |
2009-05-01 |
Sanko Junyaku Co., Ltd. |
Sondas para construir polimeros de sondas, procedimiento para construir un polimero de sondas y uso del mismo.
|
|
EP2253717B1
(de)
*
|
2000-04-07 |
2014-04-30 |
Eiken Kagaku Kabushiki Kaisha |
Methode zur Amplifizierung von Nukleinsäuren mit Hilfe von dopplesträngigen Nukleinsäuren als Templat
|
|
US7659054B1
(en)
*
|
2000-05-23 |
2010-02-09 |
Nuvelo, Inc. |
Methods for genetic analysis of DNA to detect sequence variances
|
|
US6531283B1
(en)
|
2000-06-20 |
2003-03-11 |
Molecular Staging, Inc. |
Protein expression profiling
|
|
US6323009B1
(en)
*
|
2000-06-28 |
2001-11-27 |
Molecular Staging, Inc. |
Multiply-primed amplification of nucleic acid sequences
|
|
US6596490B2
(en)
*
|
2000-07-14 |
2003-07-22 |
Applied Gene Technologies, Inc. |
Nucleic acid hairpin probes and uses thereof
|
|
US6380377B1
(en)
*
|
2000-07-14 |
2002-04-30 |
Applied Gene Technologies, Inc. |
Nucleic acid hairpin probes and uses thereof
|
|
US9708358B2
(en)
|
2000-10-06 |
2017-07-18 |
The Trustees Of Columbia University In The City Of New York |
Massive parallel method for decoding DNA and RNA
|
|
ATE356222T1
(de)
|
2000-10-06 |
2007-03-15 |
Univ Columbia |
Massives parallelverfahren zur dekodierung von dna und rna
|
|
CN1348096A
(zh)
*
|
2000-10-10 |
2002-05-08 |
栾国彦 |
一种均相特异性检测核酸的探针及应用方法
|
|
US6861222B2
(en)
*
|
2000-11-09 |
2005-03-01 |
Yale University |
Nucleic acid detection using structured probes
|
|
WO2002048401A2
(en)
|
2000-12-11 |
2002-06-20 |
Alexion Pharmaceuticals, Inc. |
Nested oligonucleotides containing hairpin for nucleic acid amplification
|
|
GB0101397D0
(en)
*
|
2001-01-19 |
2001-03-07 |
Amersham Pharm Biotech Uk Ltd |
Suppression of non-specific nucleic acid amplication
|
|
US8507662B2
(en)
|
2001-01-19 |
2013-08-13 |
General Electric Company |
Methods and kits for reducing non-specific nucleic acid amplification
|
|
US20020102557A1
(en)
*
|
2001-01-31 |
2002-08-01 |
Gentile-Davey Maria C. |
Self -complementary molecular probe
|
|
US20020142336A1
(en)
*
|
2001-02-02 |
2002-10-03 |
Genome Therapeutics Corporation |
Methods for determining a nucleotide at a specific location within a nucleic acid molecule
|
|
US6573051B2
(en)
*
|
2001-03-09 |
2003-06-03 |
Molecular Staging, Inc. |
Open circle probes with intramolecular stem structures
|
|
JP2004532026A
(ja)
*
|
2001-03-30 |
2004-10-21 |
アメルシャム・バイオサイエンシーズ・アクチボラグ |
P450単一ヌクレオチド多型バイオチップ分析
|
|
US7067849B2
(en)
*
|
2001-07-17 |
2006-06-27 |
Lg Electronics Inc. |
Diode having high brightness and method thereof
|
|
JP2005501180A
(ja)
|
2001-08-31 |
2005-01-13 |
セミトゥール・インコーポレイテッド |
超小型電子ワークピースの電気化学処理のための装置及び方法
|
|
US6977148B2
(en)
|
2001-10-15 |
2005-12-20 |
Qiagen Gmbh |
Multiple displacement amplification
|
|
US6617137B2
(en)
|
2001-10-15 |
2003-09-09 |
Molecular Staging Inc. |
Method of amplifying whole genomes without subjecting the genome to denaturing conditions
|
|
US7297485B2
(en)
|
2001-10-15 |
2007-11-20 |
Qiagen Gmbh |
Method for nucleic acid amplification that results in low amplification bias
|
|
US20030165859A1
(en)
|
2001-10-23 |
2003-09-04 |
Invitrogen Corporation |
Primers and methods for the detection and discrimination of nucleic acids
|
|
US7393636B2
(en)
*
|
2001-11-08 |
2008-07-01 |
Sanko Junyaku Co., Ltd. |
Method for forming self-assembly substance using oligonucleotide synthesized by gene amplification reaction, self-assembly substance and method for detecting gene
|
|
US7198897B2
(en)
|
2001-12-19 |
2007-04-03 |
Brandeis University |
Late-PCR
|
|
US7553619B2
(en)
|
2002-02-08 |
2009-06-30 |
Qiagen Gmbh |
Detection method using dissociated rolling circle amplification
|
|
US7291459B2
(en)
*
|
2002-12-10 |
2007-11-06 |
University Of Alabama At Huntsville |
Nucleic acid detector and method of detecting targets within a sample
|
|
US20040121338A1
(en)
*
|
2002-12-19 |
2004-06-24 |
Alsmadi Osama A. |
Real-time detection of rolling circle amplification products
|
|
US9487823B2
(en)
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
|
WO2004061134A1
(en)
*
|
2002-12-27 |
2004-07-22 |
University Of Medicine And Dentistry Of New Jersey |
Method for single nucleotide polymorphism detection
|
|
US6977153B2
(en)
|
2002-12-31 |
2005-12-20 |
Qiagen Gmbh |
Rolling circle amplification of RNA
|
|
WO2004061127A2
(en)
*
|
2003-01-02 |
2004-07-22 |
University Of Rochester |
Hybridization-based biosensor containing hairpin probes and use thereof
|
|
WO2004068112A2
(en)
*
|
2003-01-28 |
2004-08-12 |
Gorilla Genomics, Inc. |
Hairpin primer amplification
|
|
WO2004074447A2
(en)
*
|
2003-02-18 |
2004-09-02 |
Applera Corporation |
Compositions and methods for multiplex analysis of polynucleotides
|
|
US8043834B2
(en)
|
2003-03-31 |
2011-10-25 |
Qiagen Gmbh |
Universal reagents for rolling circle amplification and methods of use
|
|
EP1627075A4
(de)
*
|
2003-05-09 |
2006-09-20 |
Univ Tsinghua |
Verfahren und zusammensetzungen zur optimierung von multiplex-pcr-primern
|
|
US20040248103A1
(en)
*
|
2003-06-04 |
2004-12-09 |
Feaver William John |
Proximity-mediated rolling circle amplification
|
|
DE10338308B4
(de)
*
|
2003-08-15 |
2006-10-19 |
Epigenomics Ag |
Verfahren zum Nachweis von Cytosin-Methylierungen in DNA
|
|
US7598034B2
(en)
*
|
2004-01-02 |
2009-10-06 |
University Of Rochester |
Method of identifying hairpin DNA probes by partial fold analysis
|
|
WO2006020933A2
(en)
*
|
2004-08-13 |
2006-02-23 |
Stratagene California |
Dual labeled fluorescent probes
|
|
ES2668467T3
(es)
*
|
2004-10-18 |
2018-05-18 |
Brandeis University |
Métodos de amplificación LATE y secuenciación de un ácido nucleico
|
|
US20060194222A1
(en)
*
|
2004-10-20 |
2006-08-31 |
Stratagene California |
Triplex probe compositions and methods for polynucleotide detection
|
|
US20060105348A1
(en)
*
|
2004-11-15 |
2006-05-18 |
Lee Jun E |
Compositions and methods for the detection and discrimination of nucleic acids
|
|
US20060275792A1
(en)
*
|
2004-11-15 |
2006-12-07 |
Lee Jun E |
Enhancement of nucleic acid amplification using double-stranded DNA binding proteins
|
|
US8309303B2
(en)
|
2005-04-01 |
2012-11-13 |
Qiagen Gmbh |
Reverse transcription and amplification of RNA with simultaneous degradation of DNA
|
|
AU2006235364A1
(en)
*
|
2005-04-08 |
2006-10-19 |
Marina Biotech, Inc. |
RNAi therapeutic for respiratory virus infection
|
|
US20070213293A1
(en)
*
|
2005-04-08 |
2007-09-13 |
Nastech Pharmaceutical Company Inc. |
Rnai therapeutic for respiratory virus infection
|
|
WO2006113770A1
(en)
|
2005-04-15 |
2006-10-26 |
Epigenomics Ag |
A method for providing dna fragments derived from a remote sample
|
|
US20070015180A1
(en)
*
|
2005-05-02 |
2007-01-18 |
Stratagene California |
Oligonucleotide probe/primer compositions and methods for polynucleotide detection
|
|
WO2007011901A2
(en)
*
|
2005-07-15 |
2007-01-25 |
Applera Corporation |
Hot start reverse transcription by primer design
|
|
EP1762627A1
(de)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
|
|
US20100173287A1
(en)
*
|
2005-10-20 |
2010-07-08 |
Hitachi, Ltd. |
Method of analyzing nucleic acid
|
|
WO2007058898A2
(en)
*
|
2005-11-10 |
2007-05-24 |
Panomics, Inc. |
Detection of nucleic acids through amplification of surrogate nucleic acids
|
|
US20070243534A1
(en)
*
|
2006-04-12 |
2007-10-18 |
Michael Seul |
Probe density considerations and elongation of self-complementary looped probes where probes are attached to a solid phase
|
|
US11001881B2
(en)
|
2006-08-24 |
2021-05-11 |
California Institute Of Technology |
Methods for detecting analytes
|
|
WO2007146154A1
(en)
*
|
2006-06-06 |
2007-12-21 |
Gen-Probe Incorporated |
Tagged oligonucleotides and their use in nucleic acid amplification methods
|
|
US7833716B2
(en)
|
2006-06-06 |
2010-11-16 |
Gen-Probe Incorporated |
Tagged oligonucleotides and their use in nucleic acid amplification methods
|
|
WO2008011004A2
(en)
|
2006-07-17 |
2008-01-24 |
Brandeis University |
Specialized oligonucleotides and their use in nucleic acid amplification and detection
|
|
US11525156B2
(en)
|
2006-07-28 |
2022-12-13 |
California Institute Of Technology |
Multiplex Q-PCR arrays
|
|
US8048626B2
(en)
|
2006-07-28 |
2011-11-01 |
California Institute Of Technology |
Multiplex Q-PCR arrays
|
|
EP2059614A4
(de)
*
|
2006-08-15 |
2010-06-30 |
Zygene Biotech Llc |
Sonden-gegensonden-zusammensetzungen und verfahren für dna- oder rna-nachweis
|
|
US11560588B2
(en)
|
2006-08-24 |
2023-01-24 |
California Institute Of Technology |
Multiplex Q-PCR arrays
|
|
DE112007002932B4
(de)
|
2006-12-01 |
2015-08-06 |
The Trustees Of Columbia University In The City Of New York |
Vierfarben DNA-Sequenzierung mittels Synthese unter Verwendung von abspaltbaren, reversiblen, fluoreszierenden Nucleotidterminatoren
|
|
CA2673017C
(en)
|
2006-12-21 |
2015-08-04 |
Gen-Probe Incorporated |
Methods and compositions for nucleic acid amplification
|
|
DK3101141T3
(da)
|
2007-06-08 |
2020-02-03 |
Epigenomics Ag |
Fremgangsmåde til methyleringsanalyse
|
|
US7811764B2
(en)
*
|
2007-08-14 |
2010-10-12 |
University Of Rochester |
Hybridization-based biosensor containing hairpin probes and use thereof
|
|
US9115163B2
(en)
|
2007-10-19 |
2015-08-25 |
The Trustees Of Columbia University In The City Of New York |
DNA sequence with non-fluorescent nucleotide reversible terminators and cleavable label modified nucleotide terminators
|
|
EP4310194A3
(de)
|
2007-10-19 |
2024-10-16 |
The Trustees of Columbia University in the City of New York |
Entwurf und synthese von spaltbaren fluoreszierenden nukleotiden als reversible terminatoren zur dna-sequenzierung durch synthese
|
|
WO2009061783A2
(en)
|
2007-11-05 |
2009-05-14 |
University Of Rochester |
Dna microarray having hairpin probes tethered to nanostructured metal surface
|
|
US20090197254A1
(en)
*
|
2007-12-14 |
2009-08-06 |
Ming-Chou Lee |
Variant scorpion primers for nucleic acid amplification and detection
|
|
KR100987352B1
(ko)
*
|
2008-04-15 |
2010-10-12 |
주식회사 인트론바이오테크놀로지 |
비특이 증폭을 감소시킬 수 있는 pcr용 프라이머 및이를 이용한 pcr 방법
|
|
EP2406394B1
(de)
|
2009-03-12 |
2014-01-08 |
Brandeis University |
Reagentien und verfahren für pcr
|
|
WO2010108325A1
(zh)
*
|
2009-03-26 |
2010-09-30 |
厦门艾德生物医药科技有限公司 |
一种用于核酸扩增的环形引物及其应用
|
|
AU2010266234B2
(en)
|
2009-07-01 |
2013-07-25 |
Gen-Probe Incorporated |
Methods and compositions for nucleic acid amplification
|
|
DK2272978T3
(da)
*
|
2009-07-10 |
2012-07-23 |
Biotrin Internat Ltd |
Højfølsom hurtig isotermisk fremgangsmåde til påvisning af punktmutationer og SNP´er
|
|
US8815515B1
(en)
|
2009-09-24 |
2014-08-26 |
University Of Utah Research Foundation |
Methods, compositions, and kits for rare allele detection
|
|
WO2011059686A2
(en)
|
2009-10-29 |
2011-05-19 |
Wisconsin Alumni Research Foundation |
Detection of b-cell activating factor as a biomaker for antibody mediated rejection in transplant recipients
|
|
US9845492B2
(en)
*
|
2009-12-21 |
2017-12-19 |
Seegene, Inc. |
TSG primer target detection
|
|
US8940487B2
(en)
*
|
2010-02-09 |
2015-01-27 |
UmiTaq Bio |
Methods and compositions for universal detection of nucleic acids
|
|
EP2638178B1
(de)
*
|
2010-11-10 |
2016-10-05 |
Brandeis University |
Verfahren und kits zum nachweis und zur identifikation von mykobakterien
|
|
WO2012075231A1
(en)
|
2010-12-03 |
2012-06-07 |
Brandeis University |
Methods and kits for detecting nucleic acid mutants in wild-type populations
|
|
EP2697657B8
(de)
|
2011-04-15 |
2017-08-16 |
Becton, Dickinson and Company |
Mikrofluidischer abtastender echtzeit-thermocycler und verfahren zur optischen detektion mittels synchronisierter thermozyklierung und abtastung
|
|
EP2773892B1
(de)
|
2011-11-04 |
2020-10-07 |
Handylab, Inc. |
Vorrichtung zur vorbereitung von polynukleotidproben
|
|
US10472683B2
(en)
*
|
2012-06-01 |
2019-11-12 |
Akron Biotechnology, LLC. |
Detection of Mycoplasma in cell cultures and cell culture derived biologicals
|
|
US9909159B2
(en)
*
|
2013-02-07 |
2018-03-06 |
Rutgers, The State University Of New Jersey |
Highly selective nucleic acid amplification primers
|
|
US20140274779A1
(en)
*
|
2013-03-15 |
2014-09-18 |
Abbott Molecular Inc. |
Multiplex allele detection
|
|
US10648026B2
(en)
|
2013-03-15 |
2020-05-12 |
The Trustees Of Columbia University In The City Of New York |
Raman cluster tagged molecules for biological imaging
|
|
US10975371B2
(en)
*
|
2014-04-29 |
2021-04-13 |
Illumina, Inc. |
Nucleic acid sequence analysis from single cells
|
|
CA3060708A1
(en)
*
|
2014-04-29 |
2015-11-05 |
Illumina, Inc |
Multiplexed single cell gene expression analysis using template switch and tagmentation
|
|
GB201416459D0
(en)
|
2014-09-17 |
2014-10-29 |
Atlas Genetics Ltd |
Detection method
|
|
EP3204517B1
(de)
|
2014-10-10 |
2021-08-11 |
Rutgers, the State University of New Jersey |
Polymerasekettenreaktion-primer und -sonden für mycobacterium tuberculosis
|
|
KR101742681B1
(ko)
|
2015-01-30 |
2017-06-01 |
에스디 바이오센서 주식회사 |
상보적 염기서열 내지는 미스-매치된 염기를 포함하는 상보적인 염기서열과 연결된 pcr 프라이머 및 이를 이용한 핵산 증폭 방법
|
|
US9708647B2
(en)
|
2015-03-23 |
2017-07-18 |
Insilixa, Inc. |
Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
|
|
US9499861B1
(en)
|
2015-09-10 |
2016-11-22 |
Insilixa, Inc. |
Methods and systems for multiplex quantitative nucleic acid amplification
|
|
WO2017155858A1
(en)
|
2016-03-07 |
2017-09-14 |
Insilixa, Inc. |
Nucleic acid sequence identification using solid-phase cyclic single base extension
|
|
JP6681804B2
(ja)
*
|
2016-03-30 |
2020-04-15 |
大研医器株式会社 |
変異プライマーの設計方法
|
|
CN106282353B
(zh)
*
|
2016-08-26 |
2019-12-10 |
上海翼和应用生物技术有限公司 |
一种利用发夹引物进行多重pcr的方法
|
|
EP3548635B1
(de)
*
|
2016-11-30 |
2021-04-28 |
Exosome Diagnostics, Inc. |
Verfahren zum nachweis von mutationen in plasma unter verwendung von exosomaler rna und zellfreier dna von patienten mit nicht-kleinzelligem bronchialkarzinom
|
|
CN108517354A
(zh)
*
|
2017-02-28 |
2018-09-11 |
上海茂槿生物技术有限公司 |
用于多重pcr的引物组合物
|
|
JP7687957B2
(ja)
|
2019-03-14 |
2025-06-03 |
インシリクサ, インコーポレイテッド |
時間ゲート蛍光ベースの検出のための方法およびシステム
|
|
CN109988758A
(zh)
*
|
2019-04-16 |
2019-07-09 |
上海快灵生物科技有限公司 |
一种参与聚合延伸的寡核苷酸链探针及其核酸扩增试剂盒
|
|
US20220333183A1
(en)
|
2019-10-02 |
2022-10-20 |
Rutgers, The State University Of New Jersey |
Assay methods and kits for detecting rare sequence variants
|
|
CN111826421B
(zh)
*
|
2020-07-09 |
2021-09-21 |
广州迈景基因医学科技有限公司 |
一种pcr随机引物和使用其构建靶向测序文库的方法
|
|
WO2022072731A1
(en)
*
|
2020-09-30 |
2022-04-07 |
Ascella Biosystems, Inc. |
Rapid and highly sensitive luminescent biomolecule detection
|
|
CN116179655A
(zh)
*
|
2021-11-29 |
2023-05-30 |
北京迅识科技有限公司 |
一种实时荧光定量检测探针
|
|
CN113862339B
(zh)
*
|
2021-12-01 |
2022-03-22 |
广州滴纳生物科技有限公司 |
核酸组合产品、检测试剂盒和扩增靶核酸的方法
|
|
WO2024170770A1
(en)
|
2023-02-16 |
2024-08-22 |
Asecud Sa |
High nucleic acid sequence discrimination using a multifaceted nucleic acid molecule
|
|
EP4488384A1
(de)
*
|
2023-07-05 |
2025-01-08 |
Infiniplex Ltd. |
Primer zur selektiven amplifikation seltener zielsequenzen
|